[{"data":1,"prerenderedAt":428},["ShallowReactive",2],{"slug-top-digital-health-trends":3},{"post":4,"relatedPosts":192,"relatedBooks":339},{"id":5,"date":6,"date_gmt":7,"guid":8,"modified":10,"modified_gmt":11,"slug":12,"status":13,"type":14,"link":15,"title":16,"content":18,"excerpt":21,"author":23,"featured_media":24,"comment_status":25,"ping_status":25,"sticky":26,"template":27,"format":28,"meta":29,"categories":30,"tags":33,"project_category":43,"contact_email_category":49,"yst_prominent_words":50,"class_list":61,"better_featured_image":84,"acf":121,"yoast_meta":136,"_links":139},34041,"2024-08-29T11:43:13","2024-08-29T09:43:13",{"rendered":9},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=34041&_wpnonce=7a602e7496&status=auto-draft&type=post","2024-09-04T08:58:05","2024-09-04T06:58:05","top-digital-health-trends","publish","post","https:\u002F\u002Fmedicalfuturist.com\u002Ftop-digital-health-trends",{"rendered":17},"The Top 20 Digital Health Trends For The Near Future: Here Is The 2024 Ebook",{"rendered":19,"protected":20},"\n\u003Cp>What is going to happen in the future of medicine? What will healthcare look like? And how will our roles change as healthcare goes increasingly digital? Which digital health trends are worthy of attention and which will prove to be just hype? These are some of the questions most often asked by healthcare professionals and industry experts. \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>In the 2024 update of \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fleanpub.com\u002Ftop-20-digital-health-trends\u002F\" target=\"_blank\">The Top 20 Digital Health Trends For The Near Future\u003C\u002Fa> we highlighted 20 developments likely to happen in the upcoming 2-5 years. They are based on our analyses of trends and relevant technologies that we have been constantly monitoring.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>We would encourage you to get a copy on LeanPub for our exclusive insights into those 20 trends that we believe will have the most significance in shaping the digital health landscape in the near future. \u003C\u002Fp>\n\n\n\n\u003Cp>If you are still on the fence, we prepared this article with 3 trends discussed in the e-book, which provides a glimpse of what is further elaborated in it.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">“Around the pill” strategies indicate the future business model for the pharmaceutical industry\u003C\u002Fh3>\n\n\n\n\u003Cp>Get a prescription, take your medication, report any side effects to your physician and repeat those steps for the whole duration of the treatment, which in some cases means a lifetime. This has been the traditional relationship between patients and the drug industry but is an obsolete one in the digital age.\u003C\u002Fp>\n\n\n\n\u003Cp>To revamp this stale dynamic, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fhbr.org\u002F2015\u002F07\u002Fhow-pharma-can-offer-more-than-pills\" target=\"_blank\">“around the pill” strategies\u003C\u002Fa> could be an adequate solution. They involve pairing a pharmacological product with a digital health service as a package for the patient, rather than selling the product as-is. Pharma giant Roche had such a strategy in mind when it acquired startup \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.mysugr.com\u002F\" target=\"_blank\">mySugr\u003C\u002Fa>. Roche \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.businesstimes.com.sg\u002Fconsumer\u002Froches-sinking-diabetes-unit-looks-towards-a-monster-for-a-boost\" target=\"_blank\">paired mySugr’s innovative diabetes management app\u003C\u002Fa> with their existing Accu-Chek Guide glucose meter to create the mySugr Bundle. This bundle augmented diabetics’ management of their condition. They further continued to integrate the app with other devices like \u003Ca href=\"https:\u002F\u002Fwww.mobihealthnews.com\u002Fnews\u002Froches-mysugr-app-integrate-novo-nordisks-smart-insulin-pens\" target=\"_blank\" rel=\"noreferrer noopener\">Novo Nordisk’s smart insulin pens in 2021\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>Other companies like Partners Healthcare Center and Japanese drug maker Daichii-Sankyo also partnered for \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.mobihealthnews.com\u002F40991\u002Fwhy-partners-and-daiichi-sankyo-partnered-on-an-afib-remote-patient-monitoring-pilot\" target=\"_blank\">an “around the pill” digital offering\u003C\u002Fa> of their own for cardiac patients; and this approach is one that pharma companies, providers and payers alike will favour in the coming years given how it makes the offering more attractive to all parties involved.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Portable diagnostic device manufacturers might want to follow the path of handheld ECG companies\u003C\u002Fh3>\n\n\n\n\u003Cp>Bringing clinical-grade portable diagnostic devices that populate the digital health landscape from the concept stage into clinical practice relies on regulatory measures. Traditionally, this can represent several years if not decades-long processes. To accelerate these in an effective manner, companies could look at the path taken by manufacturers of portable ECG monitors like \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.alivecor.com\u002F\" target=\"_blank\">AliveCor\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>Since releasing its first FDA-approved portable ECG device in 2012, the company has pushed to have its devices tested in clinical trials while refining their design. By 2022, AliveCor’s products were tested in \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fs41746-020-00333-z\" target=\"_blank\">more than 60 clinical studies\u003C\u002Fa>, integrated technologies like AI and had their device \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.jacc.org\u002Fdoi\u002Ffull\u002F10.1016\u002Fj.jacc.2018.03.003\" target=\"_blank\">deemed comparable\u003C\u002Fa> to a traditional (and bulky) 12-lead ECG by a study.\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F12\u002F128_tmf_illu-768x432.png\" alt=\"Kardia ECG evolution\" class=\"wp-image-25529\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F12\u002F128_tmf_illu-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F12\u002F128_tmf_illu-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F12\u002F128_tmf_illu-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F12\u002F128_tmf_illu-512x288.png 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F12\u002F128_tmf_illu.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Cp>As such devices have the longest track record of regulatory approvals and studies in digital health, companies developing other technologies might want to follow in their footsteps. They could similarly lead the regulatory race and have an edge over their competitors while helping create a more regulated landscape for secure adoption.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Generative AI could be the ultimate interface between physicians and AI\u003C\u002Fh3>\n\n\n\n\u003Cp>In the past two years, \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fgenerative-ai-explained-its-impact-and-future-in-healthcare\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">generative AI\u003C\u002Fa> has swept across the globe like a whirlwind, bringing about astonishing advancements. The most striking breakthrough is that suddenly, almost anyone in the world can use artificial intelligence, which was previously the plaything of only a very few.\u003C\u002Fp>\n\n\n\n\u003Cp>Based on the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fchatgpt-in-healthcare-what-the-science-says\u002F\" target=\"_blank\">first published studies\u003C\u002Fa>, three main areas of focus for ChatGPT emerged, namely 1. clinical use, 2. answering medical questions and assisting in education, and 3. scientific writing and research. \u003C\u002Fp>\n\n\n\n\u003Cp>But to grasp the full scope of generative AI potential, we need to talk about another key concept that will play a significant role in the transformation of medicine: \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhy-it-is-important-to-understand-multimodal-large-language-models-in-healthcare\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">multimodality\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cimg decoding=\"async\" src=\"https:\u002F\u002Flh7-rt.googleusercontent.com\u002Fdocsz\u002FAD_4nXf-CuXVM7tUJVcnAphZy0QDWEflziJOjYN0m1VTl50M9S0b_cAhf8u54v1gUursjgolK0UjiXHsu0I6Gmh8ifyG1GRCJ94YZ32UZzbuobAaglk0G-klwFlTzjkcei5z4Ax-ZNWTLvS97VQkwsuxdH3k-wVo?key=fnJ6ggDn3AF2QRwDD5s_hw\" style=\"width: 1800px;\">\u003C\u002Fp>\n\n\n\n\u003Cp>A multimodal system can process and interpret multiple types of input data, such as text, images, audio, and video, simultaneously. Current medical AIs only process one type of data, for example, text or X-ray images. \u003C\u002Fp>\n\n\n\n\u003Cp>The development of multimodal large language models (M-LLMs) is crucial for the future of medicine as they can process and interpret multiple types of data simultaneously, unlike current unimodal AI systems. This will enable comprehensive analysis in medicine, helping communication between healthcare providers and patients speaking different languages, and serve as a central hub for various unimodal AI applications in hospitals.\u003C\u002Fp>\n\n\n\n\u003Cp>There is still a long way to go before these generative AI tools can safely assist physicians in diagnostic work or can indeed serve as a central hub in a clinic. “Everyday” models are not suitable for this purpose; algorithms specifically trained for medical use will be needed, tested and regulated.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Healthcare-defining trends\u003C\u002Fh3>\n\n\n\n\u003Cp>We hope that these 3 glimpses gave you an idea of what more to expect out of the full e-book on the healthcare-defining trends for the near future. Across each of its 20 sections, we further walk you through that area with relevant descriptions and examples that we find interesting. Moreover, we include reading suggestions at the end of every section, which you can turn to so as to dive deeper into the subject. \u003C\u002Fp>\n\n\n\n\u003Cp>We also hope that reading the\u003Ca href=\"https:\u002F\u002Fleanpub.com\u002Ftop-20-digital-health-trends\u002F\" target=\"_blank\" rel=\"noreferrer noopener\"> e-book\u003C\u002Fa> will help provide more context around digital health developments and where the field is headed in the coming years. And do share your feedback with us once you’ve read it through!\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cem>Written by Dr. Bertalan Meskó & Dr. Pranavsingh Dhunnoo\u003C\u002Fem>\u003C\u002Fp>\n\n\n\n\u003Cdiv style=\"height:100px\" aria-hidden=\"true\" class=\"wp-block-spacer\">\u003C\u002Fdiv>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",false,{"rendered":22,"protected":20},"\u003Cp>Our exclusive insights into those 20 trends that we believe will have the most importance in shaping the digital health landscape in the near future.\u003C\u002Fp>\n",16,57837,"closed",true,"","standard",{"_acf_changed":20,"footnotes":27},[31,32],6261,798,[34,35,36,37,38,39,40,41,42],6043,138,224,6981,591,6983,723,6985,734,[44,45,46,47,48],947,948,950,951,952,[],[51,52,53,54,55,56,57,58,59,60],2173,5505,1571,1617,1681,1687,1709,1713,1883,2157,[62,14,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78,79,80,81,82,83],"post-34041","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-forecast","category-digital-health-research","tag-cdc","tag-alivecor","tag-ecg","tag-around-the-pill","tag-portable-diagnostics","tag-daichii-sankyo","tag-telemedicine","tag-coronavirus-self-checker","tag-chatbots","project_category-company","project_category-developers","project_category-medical-professionals","project_category-patients","project_category-policy-makers",{"id":24,"alt_text":27,"caption":27,"description":27,"media_type":85,"media_details":86,"post":5,"source_url":120},"image",{"width":87,"height":88,"file":89,"filesize":90,"sizes":91,"image_meta":117},1920,1280,"2024\u002F08\u002FTop-20-DH-trends-ebook.jpg",127436,{"medium":92,"large":99,"thumbnail":105,"medium_large":110,"1536x1536":111},{"file":93,"width":94,"height":95,"mime-type":96,"filesize":97,"source_url":98},"Top-20-DH-trends-ebook-370x208.jpg",370,208,"image\u002Fjpeg",7204,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002FTop-20-DH-trends-ebook-370x208.jpg",{"file":100,"width":101,"height":102,"mime-type":96,"filesize":103,"source_url":104},"Top-20-DH-trends-ebook-768x512.jpg",768,512,23456,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002FTop-20-DH-trends-ebook-768x512.jpg",{"file":106,"width":107,"height":107,"mime-type":96,"filesize":108,"source_url":109},"Top-20-DH-trends-ebook-150x150.jpg",150,3008,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002FTop-20-DH-trends-ebook-150x150.jpg",{"file":100,"width":101,"height":102,"mime-type":96,"filesize":103,"source_url":104},{"file":112,"width":113,"height":114,"mime-type":96,"filesize":115,"source_url":116},"Top-20-DH-trends-ebook-1536x1024.jpg",1536,1024,64062,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002FTop-20-DH-trends-ebook-1536x1024.jpg",{"aperture":118,"credit":27,"camera":27,"caption":27,"created_timestamp":118,"copyright":27,"focal_length":118,"iso":118,"shutter_speed":118,"title":27,"orientation":118,"keywords":119},"0",[],"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002FTop-20-DH-trends-ebook.jpg",{"cta_type":122,"cta_color":27,"subtitle":27,"related_books":123,"related_posts_footer":127,"related_posts":20,"key_takeaways":131},"subscribe",[124,125,126],24764,30419,24761,[128,129,130],14848,57779,57335,[132,134],{"title":133},"\u003Cp>Using futures methods, we put together a list of the 20 most important digital health and healthcare AI trends.\u003C\u002Fp>\n",{"title":135},"\u003Cp>In this article, we highlight three examples of such trends from the e-book we just updated.\u003C\u002Fp>\n",{"yoast_wpseo_title":137,"yoast_wpseo_metadesc":138,"yoast_wpseo_canonical":15},"Top 20 Digital Health Trends For The Near Future: 2024 Ebook","Our exclusive insights into those 20 trends that we believe will have the most importance in shaping the digital health landscape in the near future.",{"self":140,"collection":146,"about":149,"author":152,"replies":155,"version-history":158,"predecessor-version":162,"wp:featuredmedia":166,"wp:attachment":169,"wp:term":172,"curies":188},[141],{"href":142,"targetHints":143},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F34041",{"allow":144},[145],"GET",[147],{"href":148},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts",[150],{"href":151},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftypes\u002Fpost",[153],{"embeddable":26,"href":154},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fusers\u002F16",[156],{"embeddable":26,"href":157},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=34041",[159],{"count":160,"href":161},36,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F34041\u002Frevisions",[163],{"id":164,"href":165},57887,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F34041\u002Frevisions\u002F57887",[167],{"embeddable":26,"href":168},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F57837",[170],{"href":171},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=34041",[173,176,179,182,185],{"taxonomy":174,"embeddable":26,"href":175},"category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=34041",{"taxonomy":177,"embeddable":26,"href":178},"post_tag","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=34041",{"taxonomy":180,"embeddable":26,"href":181},"project_category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=34041",{"taxonomy":183,"embeddable":26,"href":184},"contact_email_category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=34041",{"taxonomy":186,"embeddable":26,"href":187},"yst_prominent_words","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=34041",[189],{"name":190,"href":191,"templated":26},"wp","https:\u002F\u002Fapi.w.org\u002F{rel}",[193],{"id":130,"date":194,"date_gmt":195,"guid":196,"modified":198,"modified_gmt":199,"slug":200,"status":13,"type":14,"link":201,"title":202,"content":204,"excerpt":206,"author":208,"featured_media":209,"comment_status":25,"ping_status":25,"sticky":26,"template":27,"format":28,"meta":210,"categories":211,"tags":216,"project_category":226,"contact_email_category":227,"yst_prominent_words":228,"class_list":232,"better_featured_image":247,"acf":277,"yoast_meta":293,"_links":296},"2026-02-17T14:14:59","2026-02-17T13:14:59",{"rendered":197},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=57335&_wpnonce=16aa64a13b&status=auto-draft&type=post","2026-02-17T14:15:00","2026-02-17T13:15:00","gene-therapys-giant-leap-from-rare-conditions-to-common-cures","https:\u002F\u002Fmedicalfuturist.com\u002Fgene-therapys-giant-leap-from-rare-conditions-to-common-cures",{"rendered":203},"Gene Therapy’s Giant Leap: From Rare Conditions To Common Cures",{"rendered":205,"protected":20},"\n\u003Cp>Gene therapy is a medical field that aims to treat or prevent diseases by modifying the genes within a patient’s cells. It often uses vectors, typically viruses, to deliver therapeutic genes into target cells. The concept of gene therapy is to fix a genetic problem at its source. This quickly developing medical segment brought so many exciting novelties in the past year (even \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fda.gov\u002Fnews-events\u002Fpress-announcements\u002Ffda-approves-first-gene-therapy-treat-adults-metastatic-synovial-sarcoma\" target=\"_blank\">in the past few days\u003C\u002Fa>) that we wanted to provide an overview of the most important milestones from the recent period. \u003C\u002Fp>\n\n\n\n\u003Cp>Let’s start with a short overview of what gene therapy is and what the basics are worth knowing about these cutting-edge treatments. \u003C\u002Fp>\n\n\n\n\u003Cp>Gene therapy has various forms, including \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Gene replacement\u003C\u002Fstrong>: for diseases caused by a single faulty gene, gene therapy can provide a working copy of that gene to restore normal function. An example of this is Luxturna, which treats Leber’s congenital amaurosis, a form of inherited blindness, by providing a functional copy of the RPE65 gene.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Gene augmentation\u003C\u002Fstrong>: this broader category involves adding new genes to cells, either to replace faulty ones or to enhance cellular functions. An example is Zolgensma, which treats spinal muscular atrophy (SMA) by adding a functional copy of the SMN1 gene to replace the missing or nonfunctional one, thereby restoring muscle function.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Gene silencing\u003C\u002Fstrong>: for diseases caused by overactive genes, therapy can “silence” those genes to reduce their harmful effects. An example is Onpattro (Patisiran), which treats hereditary transthyretin-mediated amyloidosis by using RNA interference to silence the TTR gene, reducing the production of the harmful amyloid protein.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Gene editing\u003C\u002Fstrong>: technologies like \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-state-of-crispr-clinical-trials-and-their-future-potentials\" target=\"_blank\" rel=\"noreferrer noopener\">CRISPR\u003C\u002Fa> allow scientists to edit the genetic code to correct mutations. Casgevy is the first approved CRISPR-based therapy, receiving regulatory approval in 2023 for sickle cell disease. \u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Prosthetic gene therapy\u003C\u002Fstrong> aims to enable cells to take on new functions that they do not naturally perform. One example is vision restoration gene therapy, which aims to restore vision in patients with end-stage retinal diseases by delivering light-sensitive proteins into the remaining cells of the retina, rendering them light-sensitive and enabling them to signal visual information to the brain. No approved therapies exist yet, but promising research is underway.\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg decoding=\"async\" src=\"https:\u002F\u002Flh7-rt.googleusercontent.com\u002Fdocsz\u002FAD_4nXc8RwA75w3xXlAXYQoC3InSuZxNfk09DC7VDiDo-7-W-GlUsmicJkyh4QbU9KafKhub6SQH4MM6j2KwC12tqJnSkYrRN5aIBOKjfmDTuVC2h9dJTGopnpqjvTwG8EZnXSUDltaA8hLlTwSPvr6kayA7vzAT?key=E7Oc6LH-jUx-IzXAjsJ4HQ\" alt=\"\"\u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The method of delivery can be categorised into two main approaches: \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>In \u003Cstrong>in vivo gene therapy\u003C\u002Fstrong>, a vector (typically, a virus) is introduced to the patient, which then achieves the desired biological effect by passing the genetic material (e.g. for a missing protein) into the patient’s cells.  \u003C\u002Fli>\n\n\n\n\u003Cli>In \u003Cstrong>ex vivo gene therapies\u003C\u002Fstrong>, such as CAR-T therapeutics, the patient’s own cells (autologous) or healthy donor cells (allogeneic) are modified outside the body (hence, ex vivo) using a vector to express a particular protein.\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cp>Gene therapy is classified into two types by the type of cell it affects: \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Somatic cell therapy (SCGT) \u003C\u002Fstrong>affects non-reproductive cells and is not inherited by offspring. \u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Germline gene therapy (GGT)\u003C\u002Fstrong> affects reproductive cells and can be passed down. Countries like Australia, Canada, Germany, Israel, Switzerland, and the Netherlands prohibit GGT in humans due to ethical concerns.\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cp>The delivery of DNA into cells can be accomplished by multiple methods: \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Viral vectors\u003C\u002Fstrong>: recombinant viruses, often preferred for their efficiency and specificity\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Non-viral methods\u003C\u002Fstrong>: naked DNA or DNA complexes, offering lower immunogenicity\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cblockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n\u003Cp>It is impossible to paint a comprehensive picture of this complex field without writing a novel, so \u003Cstrong>we decided to focus only on the latest developments\u003C\u002Fstrong>, to show the most recent updates and peek into the near future, estimating the immediate progress.\u003C\u002Fp>\n\u003C\u002Fblockquote>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">The first regulatory approval in the world for a CRISPR-based therapy\u003C\u002Fh2>\n\n\n\n\u003Cp>Casgevy, from Vertex Pharmaceuticals and CRISPR Therapeutics was approved in November 2023 in the United Kingdom for treating the blood disorders sickle cell disease and beta thalassemia for patients 12 and older. This is a one-time treatment, and \u003Ca href=\"https:\u002F\u002Fmedcitynews.com\u002F2023\u002F11\u002Fu-k-is-first-to-approve-a-crispr-based-therapy-covering-two-blood-disorders\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">here is how it works\u003C\u002Fa>: \u003C\u002Fp>\n\n\n\n\u003Cp>“Casgevy is made by collecting a patient’s stem cells from the bone marrow. In a lab, CRISPR is used to edit a gene in those cells to produce high levels of fetal hemoglobin. Before these modified stem cells are administered, a conditioning regimen is required to kill the remaining cells in a patient that are making faulty hemoglobin. Infused into the patient, the modified stem cells make their way to the bone marrow.\u003C\u002Fp>\n\n\n\n\u003Cp>Patients may need to remain hospitalized for at least a month while those cells take up residence in the bone marrow and start producing red blood cells that incorporate fetal hemoglobin.”\u003C\u002Fp>\n\n\n\n\u003Cp>The \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fda.gov\u002Fnews-events\u002Fpress-announcements\u002Ffda-approves-first-gene-therapies-treat-patients-sickle-cell-disease\" target=\"_blank\">FDA approval\u003C\u002Fa> came about a month later, also clearing Lyfgenia, which uses a lentiviral vector for genetic modification and is approved for the treatment of patients 12 years of age and older with sickle cell disease and a history of vaso-occlusive events. \u003C\u002Fp>\n\n\n\n\u003Cp>The latest \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fda.gov\u002Fnews-events\u002Fpress-announcements\u002Ffda-approves-first-gene-therapy-treat-adults-metastatic-synovial-sarcoma\" target=\"_blank\">FDA-approved treatment is Tecelra\u003C\u002Fa>, a gene therapy indicated for the treatment of adults with unresectable or metastatic synovial sarcoma. Tecelra is also the first FDA-approved T cell receptor (TCR) gene therapy, administered as a single intravenous dose.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">A baby born deaf can hear after breakthrough gene therapy\u003C\u002Fh2>\n\n\n\n\u003Cp>Opal Sandy was born with a rare genetic condition, auditory neuropathy, and was completely deaf due to the disruption of nerve impulses traveling from the inner ear to the brain.\u003C\u002Fp>\n\n\n\n\u003Cp>She was the first patient treated in a \u003Ca href=\"https:\u002F\u002Fwww.senselab.neurosciences.medschl.cam.ac.uk\u002Four-research\u002Fchord-gene-therapy-clinical-trial\" target=\"_blank\" rel=\"noreferrer noopener\">global gene therapy trial\u003C\u002Fa>, and within four weeks of having the gene therapy infusion to her right ear, \u003Ca href=\"https:\u002F\u002Fwww.cuh.nhs.uk\u002Fnews\u002Fbaby-born-deaf-can-hear-after-breakthrough-gene-therapy\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Opal responded to sound\u003C\u002Fa>, even with the cochlear implant in her left ear switched off. The 24-week checkup confirmed close to normal hearing levels for soft sounds, such as whispering, in her treated ear.\u003C\u002Fp>\n\n\n\n\u003Cp>According to the reports, at the age of 18 months, the baby girl was able to respond to her parents’ voices and started saying basic words, such as “Dada” and “bye-bye.”\u003C\u002Fp>\n\n\n\n\u003Cp>Along very similar lines, \u003Ca href=\"https:\u002F\u002Fwww.thelancet.com\u002Fjournals\u002Flancet\u002Farticle\u002FPIIS0140-6736(23)02874-X\u002Fabstract\" target=\"_blank\" rel=\"noreferrer noopener\">a research team from China reported\u003C\u002Fa> that six kids with a type of hereditary deafness received an experimental gene therapy injected into one of their ears. Five out of the six children experienced significant improvements in their hearing, with their auditory thresholds improving by 40-57 decibels. This enhancement in hearing ability also led to improved speech perception in these children.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Small-scale human trial shows promise in lowering cholesterol\u003C\u002Fh2>\n\n\n\n\u003Cp>Following the previous, existing use cases of gene therapies, it is worth discussing what potential we see in this area. The next examples are not patient-ready innovations yet, but show how versatile help we can expect from these technologies.\u003C\u002Fp>\n\n\n\n\u003Cp>While \u003Ca href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fd41586-023-03543-z\" target=\"_blank\" rel=\"noreferrer noopener\">the VERVE-101\u003C\u002Fa> trial only included 10 participants with heterozygous familial hypercholesterolemia (HeFH), which causes lifelong high levels of low-density lipoprotein (LDL) cholesterol, the \u003Ca href=\"https:\u002F\u002Fwww.vervetx.com\u002Fsites\u002Fdefault\u002Ffiles\u002F2023-11\u002FVerve_AHA_2023_LBS_for%20website.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">interim results are promising\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg decoding=\"async\" src=\"https:\u002F\u002Flh7-rt.googleusercontent.com\u002Fdocsz\u002FAD_4nXfUVm0t7UGDQv074N14SXAfbAngwdUCJX8eOtjHszpPdr2hSKQJsZ2YnPf2JK6IDS7B34LJj_A-qrTcHjAgsMXPksGTVj5AckdwEISTMq66k2vVwVPTgr3R0R7g-PXNweoiMplPaakS1DLXI5cDEnXXk5xR?key=E7Oc6LH-jUx-IzXAjsJ4HQ\" alt=\"\"\u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The trial used a treatment called VERVE-101, which involves a one-time injection that permanently deactivates the PCSK9 gene in the liver. This gene is known to regulate LDL levels, a significant contributor to heart disease. By turning off PCSK9, the treatment successfully reduced LDL cholesterol levels by up to 55% in participants.\u003C\u002Fp>\n\n\n\n\u003Cp>This was a Phase-1 trial so there is still a long way to go, but imagine the possibilities of having a one-time injection that could get rid of high cholesterol for good! \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Gene therapy relieves back pain and repairs damaged discs in mice\u003C\u002Fh2>\n\n\n\n\u003Cp>Here is \u003Ca href=\"https:\u002F\u002Fnews.osu.edu\u002Fgene-therapy-relieves-back-pain-repairs-damaged-disc-in-mice\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">an interesting new area\u003C\u002Fa> for gene therapies! If you suffer from back pain due to a damaged disc, this might be great news for you. It seems it works in animal studies:\u003C\u002Fp>\n\n\n\n\u003Cp>“Scientists engineered nanocarriers using mouse connective-tissue cells called fibroblasts as a model of skin cells and loaded them with genetic material for a protein key to tissue development.\u003C\u002Fp>\n\n\n\n\u003Cp>The team injected a solution containing the carriers into damaged discs in mice at the same time the back injury occurred.”\u003C\u002Fp>\n\n\n\n\u003Cp>It’s one thing that gene therapies have been proven to be effective in certain genetic conditions (even though they are incredibly expensive), but how about relieving back pain? \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">The costs will determine the success and accessibility\u003C\u002Fh2>\n\n\n\n\u003Cp>As the examples above show, we have seen incredible progress in gene therapies in the past decade, with many exciting results emerging just in the last year. From treating rare genetic disorders to targeting more common conditions, the potential of gene therapy has expanded remarkably. Looking ahead, the future of gene therapy is even more exciting, with applications extending into broader fields that impact millions or even hundreds of millions of people. \u003C\u002Fp>\n\n\n\n\u003Cp>However, these treatments are still incredibly, frighteningly expensive, so we cannot expect widespread use in the short term. \u003C\u002Fp>\n\n\n\n\u003Cp>The\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.bloomberg.com\u002Fnews\u002Farticles\u002F2024-03-20\u002Fworld-s-most-expensive-drug-is-now-4-25-million-gene-therapy?embedded-checkout=true\" target=\"_blank\"> world’s most expensive drug\u003C\u002Fa> is the FDA-approved gene therapy, Libmeldy, with a staggering $4.25 million for a one-time treatment. Hemgenix, with its $3.5 million price tag was the record holder before, but gene therapies like Skysona ($3 million)and Zynteglo ($2.8 million) are not cheap either. Zolgensma has a price of $2.1 million per one-time treatment. Compared to these Luxturna seems like a bargain at $425,000 per eye \u002F $850,000 per patient. The price of the latest approved gene therapy, Tecelra, has a list price of $727,000 for the one-time treatment. \u003C\u002Fp>\n\n\n\n\u003Cp>This is why research targeting more common conditions is particularly intriguing. By focusing on treatments for widespread health issues, we may eventually develop therapies that are accessible and affordable for everyone. \u003C\u002Fp>\n",{"rendered":207,"protected":20},"\u003Cp>Gene therapy can potentially cure cancer, genetic defects or infectious diseases, but the million-dollar pricetags are a major problem. We have reason for optimism. \u003C\u002Fp>\n",6,57337,{"_acf_changed":20,"footnotes":27},[212,213,214,215],7079,521,488,489,[217,218,219,220,221,222,223,224,225],7977,7979,7981,570,7983,904,7985,7987,255,[46,47],[],[229,230,231],1841,2215,2947,[233,14,63,64,65,66,67,234,235,236,237,238,239,240,241,242,243,244,245,246,81,82],"post-57335","category-tmf","category-future-medicine","category-genomics","category-personalized-medicine","tag-gene-replacement","tag-luxturna","tag-zolgensma","tag-crispr","tag-onpattro","tag-gene-editing","tag-casgevy","tag-car-t","tag-gene-therapy",{"id":209,"alt_text":248,"caption":27,"description":27,"media_type":85,"media_details":249,"post":130,"source_url":276},"gene therapy",{"width":250,"height":114,"file":251,"filesize":252,"sizes":253,"image_meta":274},1820,"2024\u002F08\u002Ftmf_article_426-01.png",560115,{"medium":254,"large":259,"thumbnail":264,"medium_large":268,"1536x1536":269},{"file":255,"width":94,"height":95,"mime-type":256,"filesize":257,"source_url":258},"tmf_article_426-01-370x208.png","image\u002Fpng",44637,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01-370x208.png",{"file":260,"width":101,"height":261,"mime-type":256,"filesize":262,"source_url":263},"tmf_article_426-01-768x432.png",432,129136,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01-768x432.png",{"file":265,"width":107,"height":107,"mime-type":256,"filesize":266,"source_url":267},"tmf_article_426-01-150x150.png",20793,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01-150x150.png",{"file":260,"width":101,"height":261,"mime-type":256,"filesize":262,"source_url":263},{"file":270,"width":113,"height":271,"mime-type":256,"filesize":272,"source_url":273},"tmf_article_426-01-1536x864.png",864,356993,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01-1536x864.png",{"aperture":118,"credit":27,"camera":27,"caption":27,"created_timestamp":118,"copyright":27,"focal_length":118,"iso":118,"shutter_speed":118,"title":27,"orientation":118,"keywords":275},[],"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01.png",{"cta_type":122,"cta_color":27,"related_posts_footer":278,"related_posts":20,"related_books":282,"subtitle":27,"key_takeaways":286},[279,280,281],57249,57079,14811,[283,284,285],52203,31417,24759,[287,289,291],{"title":288},"\u003Cp>\u003Cspan style=\"font-weight: 400;\">Gene therapy offers fantastic solutions for genetically derived diseases and shows potential in fighting cancer and certain infectious diseases. \u003C\u002Fspan>\u003C\u002Fp>\n",{"title":290},"\u003Cp>\u003Cspan style=\"font-weight: 400;\">The field is advancing at an astonishing pace. We wanted to highlight the many exciting breakthroughs research labs reported over the past year.\u003C\u002Fspan>\u003C\u002Fp>\n",{"title":292},"\u003Cp>\u003Cspan style=\"font-weight: 400;\">While these treatments are currently prohibitively expensive, there is hope for change. \u003C\u002Fspan>\u003C\u002Fp>\n",{"yoast_wpseo_title":294,"yoast_wpseo_metadesc":295,"yoast_wpseo_canonical":201},"Gene Therapy's Giant Leap: From Rare Conditions To Common Cures","Gene therapy could be a game-changer, but the million-dollar price tags are a major problem. However, with new research, we can hope it becomes affordable.",{"self":297,"collection":302,"about":304,"author":306,"replies":309,"version-history":312,"predecessor-version":316,"wp:featuredmedia":320,"wp:attachment":323,"wp:term":326,"curies":337},[298],{"href":299,"targetHints":300},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F57335",{"allow":301},[145],[303],{"href":148},[305],{"href":151},[307],{"embeddable":26,"href":308},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fusers\u002F6",[310],{"embeddable":26,"href":311},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=57335",[313],{"count":314,"href":315},10,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F57335\u002Frevisions",[317],{"id":318,"href":319},57379,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F57335\u002Frevisions\u002F57379",[321],{"embeddable":26,"href":322},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F57337",[324],{"href":325},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=57335",[327,329,331,333,335],{"taxonomy":174,"embeddable":26,"href":328},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=57335",{"taxonomy":177,"embeddable":26,"href":330},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=57335",{"taxonomy":180,"embeddable":26,"href":332},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=57335",{"taxonomy":183,"embeddable":26,"href":334},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=57335",{"taxonomy":186,"embeddable":26,"href":336},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=57335",[338],{"name":190,"href":191,"templated":26},[340],{"id":126,"date":341,"date_gmt":342,"guid":343,"modified":345,"modified_gmt":346,"slug":347,"status":13,"type":348,"link":349,"title":350,"content":352,"excerpt":354,"author":314,"featured_media":356,"comment_status":25,"ping_status":25,"template":27,"yst_prominent_words":357,"class_list":360,"better_featured_image":363,"acf":381,"yoast_meta":397,"_links":399},"2023-11-01T15:46:07","2023-11-01T14:46:07",{"rendered":344},"https:\u002F\u002Fapi.medicalfuturist.com\u002F?post_type=book&p=24761","2023-11-01T15:46:17","2023-11-01T14:46:17","tech-giants-in-healthcare","book","https:\u002F\u002Fapi.medicalfuturist.com\u002Fbooks\u002Ftech-giants-in-healthcare\u002F",{"rendered":351},"Tech Giants in Healthcare – Updated Edition",{"rendered":353,"protected":20},"\n\u003Cp>This comprehensive guide, Tech Giants in Healthcare, clarifies how and why big tech companies step into healthcare, and breaks it down from one market player to the other in what direction they are going, what tools they are using and what horizons they have in front of them.\u003C\u002Fp>\n",{"rendered":355,"protected":20},"\u003Cp>This comprehensive guide, Tech Giants in Healthcare, clarifies how and why big tech companies step into healthcare, and breaks it down from one market player […]\u003C\u002Fp>\n",53261,[358,359],1683,1595,[361,348,362,64,66,67],"post-24761","type-book",{"id":356,"alt_text":27,"caption":27,"description":27,"media_type":85,"media_details":364,"post":126,"source_url":380},{"width":365,"height":366,"file":367,"filesize":368,"sizes":369,"image_meta":378},700,906,"2020\u002F05\u002F1031_techgiants_2023-5-1-1.png",1092124,{"medium":370,"thumbnail":374},{"file":371,"width":94,"height":95,"mime-type":256,"filesize":372,"source_url":373},"1031_techgiants_2023-5-1-1-370x208.png",112044,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-1-370x208.png",{"file":375,"width":107,"height":107,"mime-type":256,"filesize":376,"source_url":377},"1031_techgiants_2023-5-1-1-150x150.png",42366,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-1-150x150.png",{"aperture":118,"credit":27,"camera":27,"caption":27,"created_timestamp":118,"copyright":27,"focal_length":118,"iso":118,"shutter_speed":118,"title":27,"orientation":118,"keywords":379},[],"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-1.png",{"leanpub_url":382,"buy_button_text":383,"preview":384},"https:\u002F\u002Fleanpub.com\u002Ftech-giants-in-healthcare","Get it on Leanpub",[385,387,389,391,393,395],{"image":386},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-10-01.png",{"image":388},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-10-02.png",{"image":390},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-10-03.png",{"image":392},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-10-04.png",{"image":394},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-10-05.png",{"image":396},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F05\u002F1031_techgiants_2023-5-1-10-06.png",{"yoast_wpseo_title":398,"yoast_wpseo_metadesc":27,"yoast_wpseo_canonical":349},"Tech 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