[{"data":1,"prerenderedAt":370},["ShallowReactive",2],{"slug-cheap-genome-sequencing-now":3},{"post":4,"relatedPosts":176,"relatedBooks":292},{"id":5,"date":6,"date_gmt":7,"guid":8,"modified":10,"modified_gmt":11,"slug":12,"status":13,"type":14,"link":15,"title":16,"content":18,"excerpt":21,"author":23,"featured_media":24,"comment_status":25,"ping_status":25,"sticky":26,"template":27,"format":28,"meta":29,"categories":30,"tags":33,"project_category":45,"contact_email_category":47,"yst_prominent_words":48,"class_list":58,"better_featured_image":79,"acf":111,"yoast_meta":121,"_links":123},15142,"2022-10-18T10:00:00","2022-10-18T08:00:00",{"rendered":9},"http:\u002F\u002Fmedicalfuturist.com\u002F?p=15142","2022-10-18T09:36:04","2022-10-18T07:36:04","cheap-genome-sequencing-now","publish","post","https:\u002F\u002Fmedicalfuturist.com\u002Fcheap-genome-sequencing-now",{"rendered":17},"What Could You Do With Cheap Genome Sequencing Now?",{"rendered":19,"protected":20},"\n\u003Cp>Genome sequencing does definitely not equal fortune telling: it cannot predict how long you will live or what your body mass index will look like. However, it can tell you a lot about your sensitivity to drugs, your family history or whether you are a carrier of monogenic conditions.\u003C\u002Fp>\n\n\n\n\u003Cp>After the Human Genome Project was completed 20 years ago (for a whopping $2.7 billion), the dream was to be able to sequence a person’s genome for 1000 USD. After this became feasible, the next dream was to make it even cheaper: now it costs around 200 USD after\u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Fthe-era-of-fast-cheap-genome-sequencing-is-here\u002F\" target=\"_blank\" rel=\"noreferrer noopener\"> Illumina’s innovation came to life\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cp>What is the next dream? To be able to analyse the data and draw clinical conclusions from that.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Wait, I can already have my genome sequenced for $100, can’t I? \u003C\u002Fh3>\n\n\n\n\u003Cp>Although it is often not trivial from the names of various service offerings, there is a difference between full genome sequencing and the sub-$100 offers that are based on “Genome-wide association studies” or GWAS in short. \u003C\u002Fp>\n\n\n\n\u003Cp>You can imagine the difference like this: your DNA is a thick book. \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Full genome sequencing\u003C\u002Fstrong> is reading the book from cover to cover. Still, we are not necessarily understanding all of the content, but we are able to read all the letters and sentences. \u003C\u002Fp>\n\n\n\n\u003Cp>Meanwhile, \u003Cstrong>GWAS\u003C\u002Fstrong> services – like 23andMe, Ancestry and the like – look into the book here and there, reading some sentences at one point, looking for a letter at another point and then using studies to find statistically relevant correlations between your results and results documented scientifically. Let’s say, ideally they provide you with an executive summary of the full story. \u003C\u002Fp>\n\n\n\n\u003Cp>The real significance of the huge price drop in full-genome sequencing – from the short-term, consumer point of view – is that it drives down the prices of all other services. You can’t sell a GWAS result for 200 dollars if anyone can get their full genomes sequenced for the same price.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What are your genes worth?\u003C\u002Fh3>\n\n\n\n\u003Cp>Certainly, with the advancement of technology, the price dropped faster and more dramatically than the fame and fortune of the blood-testing start-up, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-12-most-overhyped-technologies-in-healthcare\u002F\" target=\"_blank\">Theranos\u003C\u002Fa>. In 30 years, the price fell from billions of dollars to the millesimal of the original cost.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-768x432.jpg\" alt=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Fthe-era-of-fast-cheap-genome-sequencing-is-here\u002F\" class=\"wp-image-47569\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-768x432.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-370x208.jpg 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-1536x864.jpg 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-2048x1153.jpg 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-scaled.jpg 1919w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>That all sounds fantastic and very exciting for every science-savvy person out there, but what should the average person do with it? What could you find out with the help of cheap genome sequencing?\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What could you learn from your DNA if I gave you the data right now?\u003C\u002Fh3>\n\n\n\n\u003Cp>I have had several genetic tests in my life. Among a handful of others, I had \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fi-got-my-whole-genome-sequenced-heres-what-i-learned\u002F\" target=\"_blank\">my whole genome sequenced\u003C\u002Fa> by Dante Labs, had the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fatlas-biomed-genetic-test-review\u002F\" target=\"_blank\">genetic test from Atlas Biomed\u003C\u002Fa>, and \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fmydna-review\u002F\" target=\"_blank\">another test by MyDNA\u003C\u002Fa>. I learned valuable takeaways from all of these, helping me form a lifestyle that aims to counter my risks. Knowing that I have a higher-than-average risk of melanoma makes me especially conscious about regular dermatology checkups and minimizing the UV load on my skin. I try to fight my elevated chance of developing type 2 diabetes by eating healthy, exercising regularly, not smoking and minimising stress. The fact that I am at risk of knee arthritis is another factor in maintaining a healthy weight.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"768\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002FDNA-loads-the-gun-768x768.png\" alt=\"\" class=\"wp-image-47587\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002FDNA-loads-the-gun-768x768.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002FDNA-loads-the-gun-150x150.png 150w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002FDNA-loads-the-gun.png 1080w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Let’s see some practical, useful info you can learn from your own test:\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">a) Sensitivity to drugs\u003C\u002Fh4>\n\n\n\n\u003Cp>The \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.mydna.life\u002F\" target=\"_blank\">myDNA genetic test\u003C\u002Fa> promises to help you and your doctor personalise your treatment by selecting the most appropriate medications based on how your body metabolizes drugs and the doses that may work best for you. As a consequence, your physician could improve your health outcomes, reduce the risk of side effects and you could also save a significant amount of money by avoiding ineffective medications. It is the best embodiment of \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC2014592\u002F\" target=\"_blank\">pharmacogenetics\u003C\u002Fa> to date. Based on the cheek swab sample I provided them, the company was able to show whether I have drug sensitivity for various basic drug ingredients, as well as whether I will have side effects when taking given types of medications. Truly useful information!\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">b) Genealogy\u003C\u002Fh4>\n\n\n\n\u003Cp>One of the most common uses of DNA testing is in uncovering family genealogy. Using consumer DNA testing services, you can uncover your family lines going back several generations. You can identify your racial makeup, familial ties and geographical background. For example, I found out that I am distantly related to Benjamin Franklin, which is kind of cool. At least, I can refer to my leadership skills as something I inherited from one of my famous ancestors (well, at least I’m going to claim that…). If you have a genetic test with \u003Ca href=\"http:\u002F\u002Fwww.23andme.com\" target=\"_blank\" rel=\"noreferrer noopener\">23andme\u003C\u002Fa>, \u003Ca href=\"https:\u002F\u002Fwww.ancestry.com\u002Fdna\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">AncestryDNA\u003C\u002Fa> or \u003Ca href=\"https:\u002F\u002Fwww.familytreedna.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">FTDNA\u003C\u002Fa>, they will definitely provide you with information about your unique family history and past relations.\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">c) Information about monogenic medical conditions\u003C\u002Fh4>\n\n\n\n\u003Cp>In primary school, I had a very nice biology teacher, who tried to explain genetics through the genes which determine your hair colour. If you have parents with blond hair, you are most likely to become a blonde. However, if your dad is the carrier of brown hair genes, you might end up being brown-haired. So we have more genetic possibilities stored in ourselves than what actually appears. Concerning your health, it is really useful to know whether you have “monogenic medical conditions”. For example, a genetic test can show you whether you have any such conditions, which you might transmit to your children; and if your partner also has it, even cause health problems for them.\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">d) Information about your multifactorial medical conditions\u003C\u002Fh4>\n\n\n\n\u003Cp>Generally, there are two types of diseases. One of them is called the multifactorial disease, where genetic components and environmental factors play significant roles. When you get your genome sequenced, you will get to know certain risk factors, which show you how much chance you have of getting a particular disease later in your life. Thus, you can get to know yourself better and get personalised solutions for preventing such diseases to get you. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What you could definitely not learn from your genetic test\u003C\u002Fh3>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">1) No prophecies on your fate\u003C\u002Fh4>\n\n\n\n\u003Cp>Many believe that the sequenced genome carries information about the person’s fate itself: what kind of diseases they may have, or when they are going to die. But that is simply not true. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fgene-editing.jpg\" alt=\"tmf\" class=\"wp-image-43425\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fgene-editing.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fgene-editing-370x208.jpg 370w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Genetic tests usually provide information about how likely it is for a given person to be taken ill by a given disease, percentages and ranges for various risks that are “written” into our genetic code. Sometimes it impacts your life, sometimes it does not. It depends pretty much on your lifestyle. If you are susceptible to diabetes, but you have a healthy lifestyle, perhaps you will never be aware of that fact. However, if there are no signs of the risk of diabetes in your genetic code, but you are overweight, don’t regularly do sports and have a stressful life, you might also end up diabetic.\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">2) No definitive answers on your due date\u003C\u002Fh4>\n\n\n\n\u003Cp>Many believe that the genetic code is something static and never-changing as if written in the stone of Ayers Rock in Australia or the Rock of Gibraltar. Unfortunately, I have to disappoint everyone who thought that the genome is a constant imprint of our fate. It is rather an ever-changing roadmap where various DNA “regions” impact each other in complex and sometimes incomprehensible ways, altering it continuously.\u003C\u002Fp>\n\n\n\n\u003Cp>However, for me, the most absurd idea concerning genome sequencing was that you might find out the date of your death if you do a genetic test. It is an outright falsehood: we are not programmed through our DNA and you cannot know what and when will things happen to you. I also believe it is better that way. Let the universe work in its own ways while you work in your own.\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">3) Healthcare is not prepared for mass genome sequencing\u003C\u002Fh4>\n\n\n\n\u003Cp>Many assume that with the drop in prices and the time necessary for mapping a whole genome, the potential in genetics and genetically-related medicine is widely known in medical circles, moreover, it is leveraged by more and more medical professionals. However, I have to disappoint again. Healthcare is definitely not prepared for mass genome sequencing. Although it is not niche anymore, most general practitioners are still not prepared to make sense of your DNA report and include its findings in their everyday practices. \u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">4. No recipe for super-humans\u003C\u002Fh4>\n\n\n\n\u003Cp>A couple of years ago, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.vice.com\u002Fen_us\u002Farticle\u002Fchinas-taking-over-the-world-with-a-massive-genetic-engineering-program\" target=\"_blank\">China apparently started a massive genetic engineering program\u003C\u002Fa>: they sequenced the genome of 2000 individuals chosen as the smartest people on the planet to find out the genes which determine human intelligence. They believe(d) if they find it, they will be able to allow parents to choose the most intelligent zygote as their future kid. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-768x432.png\" alt=\"artificial womb\" class=\"wp-image-24181\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-2048x1152.png 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>I believe it is sheer nonsense. As I mentioned before, your DNA cannot determine your exact future and it definitely cannot tell your particular characteristics down to the ground. You cannot figure out your weight, intelligence, mood or any other future trait from genome sequencing since the environment, lifestyle or eating habits have just too much of an impact. It’s the same with your risks for multifactorial medical conditions. There is no definitive percentage, there are too many factors influencing such health issues.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Genetics loads the gun, lifestyle pulls the trigger\u003C\u002Fh3>\n\n\n\n\u003Cp>So while we have no impact on what we inherit from our ancestors (although the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fcrispr\u002F\" target=\"_blank\">CRISPR genome editing method\u003C\u002Fa> might bring some changes there in the future), lifestyle depends on our decisions. We can improve it with data, feedback and good technologies. Also, the more we can learn from our genome, the more precautions we can take to prevent diseases or catch them as soon as possible. \u003C\u002Fp>\n\n\n\n\u003Cp>So, do not hesitate to order a genetic test (but be careful when choosing one and do not buy an uncontrolled test), and try to make some adjustments to your lifestyle based on the results and their interpretation by a genetic counsellor or your own physician. And of course, if you have any doubts or questions, I’m more than happy to help as well! Reach out to me on \u003Ca href=\"https:\u002F\u002Fwww.facebook.com\u002Fmedicalfuturist\u002F\">Facebook\u003C\u002Fa> or \u003Ca href=\"https:\u002F\u002Ftwitter.com\u002FBerci\">Twitter\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",false,{"rendered":22,"protected":20},"\u003Cp>Genome sequencing does definitely not equal with fortune telling: it cannot predict how long you will live or what your body mass index will look like. However, it can tell you a lot about your sensitivity to drugs, your family history or whether you are a carrier of monogenic conditions.\u003C\u002Fp>\n",6,47669,"closed",true,"","standard",{"_acf_changed":20,"footnotes":27},[31,32],488,489,[34,35,36,37,38,39,40,41,42,43,44],212,522,213,655,259,260,261,262,275,289,355,[46],951,[],[49,50,51,52,53,54,55,56,57],3023,3025,1723,1727,1883,1969,1995,2045,2657,[59,14,60,61,62,63,64,65,66,67,68,69,70,71,72,73,74,75,76,77,78],"post-15142","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-genomics","category-personalized-medicine","tag-dna","tag-gc3","tag-dna-testing","tag-genome-sequencing","tag-genetic-testing","tag-genetics","tag-genome","tag-genomics","tag-healthcare","tag-innovation","tag-personalized-medicine","project_category-patients",{"id":24,"alt_text":80,"caption":27,"description":27,"media_type":81,"media_details":82,"post":5,"source_url":110},"TMF DNA sequence","image",{"width":83,"height":84,"file":85,"sizes":86,"image_meta":108},1800,1012,"2022\u002F10\u002Ftmf_article_335-v2-01.png",{"medium":87,"large":93,"thumbnail":98,"medium_large":102,"1536x1536":103},{"file":88,"width":89,"height":90,"mime-type":91,"source_url":92},"tmf_article_335-v2-01-370x208.png","370","208","image\u002Fpng","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01-370x208.png",{"file":94,"width":95,"height":96,"mime-type":91,"source_url":97},"tmf_article_335-v2-01-768x432.png","768","432","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01-768x432.png",{"file":99,"width":100,"height":100,"mime-type":91,"source_url":101},"tmf_article_335-v2-01-150x150.png","150","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01-150x150.png",{"file":94,"width":95,"height":96,"mime-type":91,"source_url":97},{"file":104,"width":105,"height":106,"mime-type":91,"source_url":107},"tmf_article_335-v2-01-1536x864.png","1536","864","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01-1536x864.png",{"aperture":109,"credit":27,"camera":27,"caption":27,"created_timestamp":109,"copyright":27,"focal_length":109,"iso":109,"shutter_speed":109,"title":27,"orientation":109},"0","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01.png",{"related_posts":20,"related_posts_footer":112,"cta_type":116,"cta_color":27,"subtitle":27,"related_books":117},[113,114,115],15120,17450,47495,"subscribe",[118,119,120],24765,30419,47427,{"yoast_wpseo_title":17,"yoast_wpseo_metadesc":122,"yoast_wpseo_canonical":15},"Genome sequencing can tell you a lot about your sensitivity to drugs, your family history or whether you're a carrier of monogenic conditions. Check it out!",{"self":124,"collection":130,"about":133,"author":136,"replies":139,"version-history":142,"predecessor-version":146,"wp:featuredmedia":150,"wp:attachment":153,"wp:term":156,"curies":172},[125],{"href":126,"targetHints":127},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15142",{"allow":128},[129],"GET",[131],{"href":132},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts",[134],{"href":135},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftypes\u002Fpost",[137],{"embeddable":26,"href":138},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fusers\u002F6",[140],{"embeddable":26,"href":141},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=15142",[143],{"count":144,"href":145},44,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15142\u002Frevisions",[147],{"id":148,"href":149},47663,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15142\u002Frevisions\u002F47663",[151],{"embeddable":26,"href":152},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F47669",[154],{"href":155},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=15142",[157,160,163,166,169],{"taxonomy":158,"embeddable":26,"href":159},"category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=15142",{"taxonomy":161,"embeddable":26,"href":162},"post_tag","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=15142",{"taxonomy":164,"embeddable":26,"href":165},"project_category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=15142",{"taxonomy":167,"embeddable":26,"href":168},"contact_email_category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=15142",{"taxonomy":170,"embeddable":26,"href":171},"yst_prominent_words","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=15142",[173],{"name":174,"href":175,"templated":26},"wp","https:\u002F\u002Fapi.w.org\u002F{rel}",[177],{"id":115,"date":178,"date_gmt":179,"guid":180,"modified":182,"modified_gmt":183,"slug":184,"status":13,"type":14,"link":185,"title":186,"content":188,"excerpt":190,"author":23,"featured_media":192,"comment_status":25,"ping_status":25,"sticky":26,"template":27,"format":28,"meta":193,"categories":194,"tags":197,"project_category":203,"contact_email_category":204,"yst_prominent_words":205,"class_list":209,"better_featured_image":218,"acf":241,"yoast_meta":248,"_links":250},"2022-10-11T10:00:00","2022-10-11T08:00:00",{"rendered":181},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=47495&_wpnonce=78901681de&status=auto-draft&type=post","2022-10-11T00:38:18","2022-10-10T22:38:18","here-is-how-you-get-friendly-with-a-i-before-it-gets-to-the-office","https:\u002F\u002Fmedicalfuturist.com\u002Fhere-is-how-you-get-friendly-with-a-i-before-it-gets-to-the-office",{"rendered":187},"Here Is How You Get Friendly With A.I. Before It Gets To The Office",{"rendered":189,"protected":20},"\n\u003Cp>If you ask a random person whether they use artificial intelligence in their everyday lives, the answer will likely be a firm negative. However, this answer is incorrect: most of us use it a good number of times every day. A.I. is everywhere around us, it just doesn’t look like the mental picture we have, which usually resembles T-1000 from Terminator 2: Judgement Day or the Borg Queen from the Star Trek series. Ugly, evil, and almost omnipotent.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"768\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_the_Borg_Queen_and_T-1000_from_Terminator_2_in_on_0e9a3e05-e6a3-4994-8fb2-5f709c019d7b-768x768.png\" alt=\"AI generated art from Midjourney algorithm\" class=\"wp-image-47499\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_the_Borg_Queen_and_T-1000_from_Terminator_2_in_on_0e9a3e05-e6a3-4994-8fb2-5f709c019d7b-768x768.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_the_Borg_Queen_and_T-1000_from_Terminator_2_in_on_0e9a3e05-e6a3-4994-8fb2-5f709c019d7b-150x150.png 150w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_the_Borg_Queen_and_T-1000_from_Terminator_2_in_on_0e9a3e05-e6a3-4994-8fb2-5f709c019d7b.png 1024w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003Cfigcaption>All images in this article were generated by Midjourney, a text-to-art algorithm. This was its take on \u003Cbr>“The Borg Queen and T-1000 from Terminator 2 in one picture”\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Most of us use A.I. all the time: when navigating through the town with an app, when opening a social media platform and scrolling through its recommendations, browsing on an online marketplace, interacting with a chatbot or talking to Siri\u002FAlexa\u002FGoogle. There are algorithms everywhere, we just don’t recognise them as artificial intelligence, although this is what they are. \u003C\u002Fp>\n\n\n\n\u003Cp>However, things will not stop at this point, and in the coming decades, we will have to form a deeper relationship with A.I. as it will become a prominent part of our daily lives on a more active level. In the healthcare setting, for example, we can be assured that A.I. will become a member of the care team – so we better figure out how to deal with it.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">A.I. will take over repetitive and data-based tasks and will transform your work\u003C\u002Fh2>\n\n\n\n\u003Cp>It is easy to determine how not to relate to this upcoming new era. Getting paralysed with desperation “A.I. will take my job and there is nothing I can do about it” (potentially with mental pictures of ending up under a bridge) is not the way. \u003C\u002Fp>\n\n\n\n\u003Cp>Ok, so how to relate? First, make it clear: yes, A.I. will take over many, many tasks from humans. And it will execute them faster, better, and cheaper. Tasks that are\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>data-based\u003C\u002Fli>\u003Cli>repetitive\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Cp>will be taken over by algorithms, whatever your line of work is. \u003C\u002Fp>\n\n\n\n\u003Cp>This process will not be materially different from what we experienced with multiple technological revolutions centuries or decades ago. Computers took over a good number of tasks from humans – accountants don’t have to do all the calculus for a giant firm on a notebook with a pencil anymore, but computers did not take the work of accountants, they lent advanced computational skills to them. Computers also created new jobs, jobs we never knew in 1980 would exist in a few decades.  \u003C\u002Fp>\n\n\n\n\u003Cp>A similar shift is expected with algorithms and machines becoming better at certain tasks. A nurse might not need to do the blood draw in the future – machines will do it better -, or try and move heavy patients alone while changing their sheets. But this will not eliminate the need for nurses, it will transform what and how they do. They will probably have more time to empathically respond to patients, more time to talk about their cases and help them understand how to manage their conditions. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Learn to deal with A.I. now, in a non-commital way\u003C\u002Fh2>\n\n\n\n\u003Cp>To prepare for the future, the best we can do is to familiarise ourselves with how artificial intelligence works – outside of our professional lives. This, again, will be a cultural transformation, and it is much better to learn it before it gets to the office. \u003C\u002Fp>\n\n\n\n\u003Cp>Midjourney, the \u003Ca href=\"https:\u002F\u002Fwww.pcworld.com\u002Farticle\u002F820518\u002Fmidjourneys-ai-art-goes-live-for-everyone.html\">text-to-art image algorithm\u003C\u002Fa> is a good example. Granted, you need to have (or register) a discord account to use it, but after that, you are free to play with it for a while, get a grasp of how it “thinks”, and what is the best way to interact with it to get the result you imagined. \u003C\u002Fp>\n\n\n\n\u003Cp>I wanted to see if Midjourney can generate a picture of a futuristic hospital, so I told it what I typically tell our graphic designers with a task like that: I’d like a picture and the topic should be “\u003Cem>futuristic, hospital, doctors, AI\u003C\u002Fem>”.\u003C\u002Fp>\n\n\n\n\u003Cp>Well, Midjourney certainly needs more details than Adam, our lead designer, as this is what I got at the first go:\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-resized is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fthe-first-4-results-of-AI-drawing.jpg\" alt=\"Futuristic doctors from the text to art algorithm Midjourney\" class=\"wp-image-47509\" width=\"804\" height=\"641\"\u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Apart from the interesting fact that futuristic doctors seem to be exclusively caucasian females in Midjourney’s books, this was quite far from the results I wanted to see. \u003C\u002Fp>\n\n\n\n\u003Cp>So I went on and defined the task better: “\u003Cem>A hospital environment with patients, beds, healthcare devices, where doctors, patients and robots work together in a futuristic hospital setting.\u003C\u002Fem>” One of the 4 results seemed to get closer to my concept, so asked Midjourney to refine the fourth picture, and we ended up with this: \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"768\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002FAI-generated-image-about-a-futuristic-hospital-setting-768x768.png\" alt=\"Futuristic hospital scene from the text-to-art algorithm Midjourney\" class=\"wp-image-47511\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002FAI-generated-image-about-a-futuristic-hospital-setting-768x768.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002FAI-generated-image-about-a-futuristic-hospital-setting-150x150.png 150w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002FAI-generated-image-about-a-futuristic-hospital-setting.png 1024w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>As this was still quite far from what I originally had in my mind – an \u003Ca class=\"img\" href=\"https:\u002F\u002Fpenji.co\u002Fisometric-design\u002F\">isometric \u003C\u002Fa>scene of a futuristic hospital, full of patients, devices, human and non-human personnel, something like \u003Ca href=\"https:\u002F\u002Fdatapopalliance.org\u002Fwp-content\u002Fuploads\u002F2022\u002F05\u002FEthics-AI-blog.jpg\"\u003C\u002Fa>this\u003C\u002Fa> or \u003Ca class=\"img\" href=\"https:\u002F\u002Fdeveloper-blogs.nvidia.com\u002Fwp-content\u002Fuploads\u002F2021\u002F06\u002FNVIDIA-Clara-Guardian-featured.png\"\u003C\u002Fa>this \u003C\u002Fa>– I tried to define the task even better, asking Midjourney to imagine an “\u003Cem>isometric image of a futuristic hospital building suit with patients in beds, machines, healthcare devices, human doctors and robots working together with AI\u003C\u002Fem>”. \u003C\u002Fp>\n\n\n\n\u003Cp>Results this time got further from my mental picture, they were neither  isometric nor grasped the buzzing futuristic hospital scene I wanted to see: \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-resized is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_isometric_image_of_a_futuristic_hospital_building_8097d939-5a17-41ff-842a-4dc2b16d519e.png\" alt=\"Neither isometric, nor buzzing image from text to art algorithm Midjourney\" class=\"wp-image-47507\" width=\"772\" height=\"772\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_isometric_image_of_a_futuristic_hospital_building_8097d939-5a17-41ff-842a-4dc2b16d519e.png 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_isometric_image_of_a_futuristic_hospital_building_8097d939-5a17-41ff-842a-4dc2b16d519e-150x150.png 150w\" sizes=\"auto, (max-width: 772px) 100vw, 772px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Ok, one last go before you get super bored with my imaginary science fiction hospital. I tried to define the task much better, by breaking my initial mental picture into shorter and simpler sentences and stressing the missing details. \u003C\u002Fp>\n\n\n\n\u003Cp>So it went: “\u003Cem>buzzing hospital emergency unit setting with many people in the picture. There are several patients in hospital beds. Lots of medical machines and devices. Several human doctors and human nurses. Also working with medical robots and A.I. Futuristic setting\u003C\u002Fem>.”\u003C\u002Fp>\n\n\n\n\u003Cp>Looks like this did not help a lot, while each of the four images incorporated some new details, none of them incorporated all of it. There are many hospital beds in the first one, a good number of healthcare workers in the second one, a robot in the third, and a sort-of-buzzing emergency unit in the last one. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-resized is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_buzzing_hospital_emergency_unit_setting_with_many_a559e934-f7ae-4a24-923b-a88a8da86c0e.png\" alt=\"Text to art AI Midjourney hospital scenes\" class=\"wp-image-47505\" width=\"763\" height=\"763\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_buzzing_hospital_emergency_unit_setting_with_many_a559e934-f7ae-4a24-923b-a88a8da86c0e.png 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_buzzing_hospital_emergency_unit_setting_with_many_a559e934-f7ae-4a24-923b-a88a8da86c0e-150x150.png 150w\" sizes=\"auto, (max-width: 763px) 100vw, 763px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>I’m not sure how long I have to keep trying to redefine the task until I eventually get there, I suppose I will exhaust the free limit of 25 tries before I succeed in my quest. But all these queries helped me understand slightly better how this particular algorithm thinks and adjust my thinking to it.\u003C\u002Fp>\n\n\n\n\u003Cp>I will take a break from Midjourney for now and will get back in a little while, trying to figure out how to get to the result I want to see. \u003C\u002Fp>\n\n\n\n\u003Cp>Is it good or useful? – you might ask. Well, yes and no. No in a way that we obviously can’t use Midjourney to generate images for publication – apart from this article. Also no in a way that after a number of tries – not all are documented above – I didn’t even get close to the picture I wanted to see.\u003C\u002Fp>\n\n\n\n\u003Cp>On the other hand, it was useful. It helped me think about my thinking process. It helped me think about the algorithm’s thinking. It was interesting to see how it gets to a visual answer and what kinds of answers it provides. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Be curious and never stop playing with new technologies\u003C\u002Fh2>\n\n\n\n\u003Cp>The above examples with Midjourney show how un-straightforward it is to use a text-to-art application – said to be the best at the moment – to make it generate the picture you want. However, it also shows that it can come up with many things, and some of these might surprise you. This is, what the algorithm thinks an overworked nurse looks like: \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-resized is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_an_overworked_nurse_in_a_hopsital_tending_for_pat_cc67d6f4-77ba-48dc-affc-79dccd29519c.png\" alt=\"Overworked nurse depicted by text to art  Midjourney\" class=\"wp-image-47503\" width=\"743\" height=\"743\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_an_overworked_nurse_in_a_hopsital_tending_for_pat_cc67d6f4-77ba-48dc-affc-79dccd29519c.png 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_an_overworked_nurse_in_a_hopsital_tending_for_pat_cc67d6f4-77ba-48dc-affc-79dccd29519c-150x150.png 150w\" sizes=\"auto, (max-width: 743px) 100vw, 743px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Quite some pieces of socio-documenting art, aren’t they?\u003C\u002Fp>\n\n\n\n\u003Cp>So I urge you to stay curious and open-minded, and grab the opportunities to play around with algorithms, should it be Midjourney, the A.I. in your favourite game, or the chatbots you interact with. Get as comfortable with them as possible and form a “relationship”, as you will need it in a few years and decades. And never think you will be left behind, instead focus on how it will enhance what you are capable of doing. \u003C\u002Fp>\n\n\n\n\u003Cp>Although I was dead-set on pushing out a header image of the algorithm, my first attempts on a “\u003Cem>16:9 ratio image of a human doctor and an A.I. doctor shaking hands in the hospital\u003C\u002Fem>” ended up with quite disturbing results (and a square image format – note: you need to use aspect ratio or the –ar command). Even if we skip the confusing faces, it is slightly unsettling how Midjourney seemed to take the “shaking hands” part a little too literally. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"768\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_A_human_doctor_and_an_AI_doctor_shaking_hands_in__d65ed142-2785-4fdd-902c-ec62d08d1cb7-768x768.png\" alt=\"Shaking hands a little too literally by the Midjourney text to art algorithm\" class=\"wp-image-47497\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_A_human_doctor_and_an_AI_doctor_shaking_hands_in__d65ed142-2785-4fdd-902c-ec62d08d1cb7-768x768.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_A_human_doctor_and_an_AI_doctor_shaking_hands_in__d65ed142-2785-4fdd-902c-ec62d08d1cb7-150x150.png 150w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Fvilaggazdasag_A_human_doctor_and_an_AI_doctor_shaking_hands_in__d65ed142-2785-4fdd-902c-ec62d08d1cb7.png 1024w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>So, to be on the safe side, I stuck with a simple command of “\u003Cem>doctor in a futuristic hospital with a big AI terminal\u003C\u002Fem> –ar 16:9″, this is the header image of this article. Pretty not bad, right? \u003C\u002Fp>\n\n\n\n\u003Cp>All in all, good job, algorithm, it was fun to work with you! \u003C\u002Fp>\n",{"rendered":191,"protected":20},"\u003Cp>To prepare for the future, the best we can do is to familiarise ourselves with how artificial intelligence works – outside of our professional lives. 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