[{"data":1,"prerenderedAt":2177},["ShallowReactive",2],{"category-genomics":3},{"category":4,"posts":42,"featured":2175,"ebooks":2176},{"id":5,"count":6,"description":7,"link":8,"name":9,"slug":10,"taxonomy":11,"parent":12,"meta":13,"acf":14,"z_taxonomy_image_url":17,"yoast_meta":18,"taxonomy_image":17,"_links":21},488,56,"Combining each individual’s genetic makeup from their DNA code with the characteristics they have helps design personalized therapies tailored to every patient’s specific needs.","https:\u002F\u002Fapi.medicalfuturist.com\u002Fcategory\u002Fgenomics\u002F","Genomics","genomics","category",0,[],{"listing_order":15,"child_category_ids":16},"11",false,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F051_genomsequence_v2.png",{"yoast_wpseo_title":19,"yoast_wpseo_metadesc":20},"Genomics - The Medical Futurist","Find the latest genomics articles from The Medical Futurist!",{"self":22,"collection":28,"about":31,"wp:post_type":34,"curies":37},[23],{"href":24,"targetHints":25},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories\u002F488",{"allow":26},[27],"GET",[29],{"href":30},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories",[32],{"href":33},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftaxonomies\u002Fcategory",[35],{"href":36},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts?categories=488",[38],{"name":39,"href":40,"templated":41},"wp","https:\u002F\u002Fapi.w.org\u002F{rel}",true,[43,261,421,562,671,820,990,1131,1253,1373,1499,1622,1742,1855,1964,2062],{"id":44,"date":45,"date_gmt":46,"guid":47,"modified":49,"modified_gmt":50,"slug":51,"status":52,"type":53,"link":54,"title":55,"content":57,"excerpt":59,"author":61,"featured_media":62,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":66,"categories":67,"tags":70,"project_category":93,"contact_email_category":94,"yst_prominent_words":95,"class_list":114,"better_featured_image":146,"acf":191,"yoast_meta":209,"_links":212},23437,"2026-05-11T10:36:13","2026-05-11T08:36:13",{"rendered":48},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=23437&_wpnonce=5e1f7e7cd0&status=auto-draft&type=post","2026-05-11T10:36:15","2026-05-11T08:36:15","the-most-pressing-issues-in-bioethics","publish","post","https:\u002F\u002Fmedicalfuturist.com\u002Fthe-most-pressing-issues-in-bioethics",{"rendered":56},"The Most Pressing Issues In Bioethics",{"rendered":58,"protected":16},"\n\u003Cp>Who owns medical and genetic data? How to regulate gene editing? Where is the boundary of enhancing physical or cognitive human capabilities? What to do with biological differences widening the gap of the haves and have-nots? Could we define where the boundary is to augment life? Will we sue robots or algorithms for medical malpractice? With the constant advancement of technology, unprecedented moral, ethical and legal concerns are surfacing. Channeling them into substantial debates will get us closer to their fair solution step by step. Here, we collected the most pressing bioethics issues.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Bioethicists\nof the world, unite!\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>In 2018, a scientist in China \u003Ca href=\"https:\u002F\u002Fwww.nytimes.com\u002F2018\u002F11\u002F26\u002Fhealth\u002Fgene-editing-babies-china.html?rref=collection%2Fsectioncollection%2Fscience&action=click&contentCollection=science&region=stream&module=inline&version=latest&contentPlacement=6&pgtype=sectionfront\">claimed to have edited\u003C\u002Fa> a gene in two human embryos and implanted them in their mother’s womb, resulting in the birth of genetically altered twin girls. The case caused international outrage in scientific circles, and a couple of months later, many \u003Ca href=\"https:\u002F\u002Fwww.theguardian.com\u002Fscience\u002F2019\u002Fmar\u002F13\u002Fscientists-call-for-global-moratorium-on-crispr-gene-editing\">scientists called for a global moratorium on gene-editing embryos\u003C\u002Fa>. However, that’s just one story from the ethically challenging situations on the edges of medical scientific innovation.\u003C\u002Fp>\n\n\n\n\u003Cp>The billionaires of Silicon Valley, as well as other\nprime examples of the “haves”, are pouring money into research of longevity and\naging, which might result in the even more widening gap between the life\nexpectancies of the affluent and the masses. Dr. David\nHimmelstein, the co-founder of the Physicians for a National Health Program and\na lecturer in medicine at Harvard Medical School, told Healthline that the \u003Ca href=\"https:\u002F\u002Fwww.healthline.com\u002Fhealth-news\u002Fcan-money-determine-how-long-you-live#2\">gap between the wealthiest and poorest Americans is already\nabout 10 years for women and 15 for men\u003C\u002Fa> – and we could expect an\nexponential increase there.\u003C\u002Fp>\n\n\n\n\u003Cp>Besides, we haven’t even touched upon bioethical topics around private and sensitive medical data, not to say genetic data. Who’s the owner, the distributor or the user of that data? What is it worth and who uses it for what purposes? Or what about connected medical devices used for healthy people? Could the use of an exoskeleton be allowed in a warehouse to enhance capabilities? What about brain implants or digital tattoos? Where should or might the augmentation of human bodies or cyborgization stop?\u003C\u002Fp>\n\n\n\n\u003Cp>We’re no longer in the realm of science fiction. These issues are real, well and alive. \u003Cstrong>While The Medical Futurist takes an overall optimistic approach to technology and emphasizes its benefits, we have to deal with the dark side – in order to take steps to counter them as soon as possible. Physicians, patients, regulators, and all other stakeholders must prepare for the coming waves of change. To do that, we need to start talking openly about the dangers we face. To spark discourse and urge bioethicists to speak a lot more and a lot louder about the most pressing \u003Cstrong>bioethics\u003C\u002Fstrong>\u003C\u002Fstrong> \u003Cstrong>issues and topics,\u003C\u002Fstrong> here’s the ultimate list of the ones we consider the most relevant.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>1) Medical and genetic data privacy\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>The most important bioethics issue of our times is how to treat data, more specifically how to treat private and sensitive medical and genetic data. How should we secure, share or trade with sensitive data? Should sensitive fitness and medical data be shared with insurance companies? What if you ate red meat and your insurance company immediately raised your insurance rates because you’re not eating healthy enough?\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-genomic-data-challenges-of-the-future\">What to do with genetic and genomic\ndata\u003C\u002Fa>\u003C\u002Fstrong>\u003Cstrong>? If you already purchased a direct-to-consumer\ngenetic test or any other one, what can companies do with your data? Can\nyou delete it or force the companies to make your genetic information\ndisappear? \u003C\u002Fstrong>\u003Cstrong>Could it be allowed for companies, research\nconglomerates or pharma enterprises to purchase or sell such data, and if anyone\ndoes that, how to set the price for it? What is the price for a single person’s\nsequenced genome? Should there be a price?\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>These are not far away and remote concerns. For example, \u003Ca href=\"https:\u002F\u002Fwww.gsk.com\u002Fen-gb\u002Fmedia\u002Fpress-releases\u002Fgsk-and-23andme-sign-agreement-to-leverage-genetic-insights-for-the-development-of-novel-medicines\u002F\">in July 2018, GlaxoSmithKline decided to invest $300 million in 23andMe\u003C\u002Fa> and forge an exclusive drug development deal with the Silicon Valley consumer genetics company to research and develop innovative new medicines and potential cures, using human genetics as the basis for discovery. Ancestry, which maintains a more than \u003Ca href=\"https:\u002F\u002Fwww.ancestry.com\u002Fcorporate\u002Fnewsroom\u002Fpress-releases\u002Fancestry-surpasses-5-million-people-dna-database-giving-customers-even-more\">5-million-person\u003C\u002Fa> consumer database of genetic information, \u003Ca href=\"https:\u002F\u002Fwww.businessinsider.com\u002Fgoogle-calico-ancestry-dna-genetics-aging-partnership-ended-2018-7\">once partnered with Google’s stealthy life-extension spinoff\u003C\u002Fa> Calico to study aging. \u003Ca href=\"https:\u002F\u002Fwww.reuters.com\u002Farticle\u002Fus-health-dna\u002Fcashing-in-on-dna-race-on-to-unlock-value-in-genetic-data-idUSKBN1KO0XC\">Caitlin Curtis, a research fellow at the University of Queensland, estimates\u003C\u002Fa> 23andMe made around $130 million from selling access to about a million genotypes, before the GSK deal, implying an average price of around $130. That means if you purchased 23andMe’s genetic test for $100-150, your genetic information could have been bought for another $130 on average price. The question is whether we are okay with that…\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"256\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FBioethics_Helix-512x256.png\" alt=\"bioethics\" class=\"wp-image-23440\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FBioethics_Helix-512x256.png 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FBioethics_Helix-768x384.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FBioethics_Helix-1536x768.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FBioethics_Helix.png 2040w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: https:\u002F\u002Fblog.helix.com\u002Fbioethics\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>2\u003C\u002Fstrong>\u003Cstrong>)\n\u003C\u002Fstrong>\u003Cstrong>Cyber\u003C\u002Fstrong>\u003Cstrong> \u003C\u002Fstrong>\u003Cstrong>attacks\u003C\u002Fstrong>\u003Cstrong> against \u003C\u002Fstrong>\u003Cstrong>medical\ndevices\u003C\u002Fstrong>\u003Cstrong>\nand systems\u003C\u002Fstrong>\u003Cstrong>\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>Do you remember \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-nhs-ransomware-attack-data-privacy-in-digital-health-part-one\">the\nWannaCry scandal\u003C\u002Fa>, the global cyber attack\nthat infected 300,000 computers in 150 countries using hacking tools? It also\ncrippled the National Health Service (NHS) in the United Kingdom. UK hospitals\nwere shut down and had to turn away non-emergency patients after ransomware\nransacked its networks. That was the complete and utter failure of the health\nIT infrastructure. \u003C\u002Fp>\n\n\n\n\u003Cp>Since that attack, not only hospitals doubled down on cybersecurity, but Microsoft also started to take cybersecurity in healthcare as seriously as never before. The ransomware \u003Ca href=\"https:\u002F\u002Fwww.beckershospitalreview.com\u002Fhealthcare-information-technology\u002F6-updates-on-the-worldwide-ransomware-attack.html\">exploited\u003C\u002Fa> a vulnerability that Microsoft had created a patch for two months earlier, but many organizations — including hospitals — had not appropriately updated their systems before the attack. \u003Cstrong>But is okaying the updates enough? And did huge medical facilities or tech companies dealing with vulnerable data even do the homework ever since?\u003C\u002Fstrong> It doesn’t seem so, although they should! Recently, \u003Ca href=\"https:\u002F\u002Ftechcrunch.com\u002F2019\u002F03\u002F17\u002Fmedical-health-data-leak\u002F\">it turned out that California-based Meditab, a health tech company was leaking thousands of doctor’s notes\u003C\u002Fa>, medical records, and prescriptions daily after a security lapse left a fax server without a password.\u003C\u002Fp>\n\n\n\n\u003Cp>The situation is not rosy regarding \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-nhs-ransomware-attack-part-ii\">the security of medical devices\u003C\u002Fa> either. In 2011, \u003Ca href=\"http:\u002F\u002Fwww.theregister.co.uk\u002F2011\u002F10\u002F27\u002Ffatal_insulin_pump_attack\u002F\">a researcher from the McAfee tech company demonstrated\u003C\u002Fa> at a conference in Miami how insulin pumps might be hacked to deliver fatal doses to diabetes patients. \u003Ca href=\"https:\u002F\u002Ftechcrunch.com\u002F2019\u002F03\u002F22\u002Fmedtronic-defibrillators-critical-flaws\u002F?fbclid=IwAR0IH13HUO1BmCTEuTOmzxXXENKZu3RIoyS_xvaSi9qVKNBmYnACFnr5kP4\">According to the latest news\u003C\u002Fa>, Homeland Security has issued a warning for a set of critical-rated vulnerabilities in Medtronic defibrillators that put the devices at risk of manipulation. \u003Cstrong>The question is – what can we do to protect wearable devices that are connected to our physiological system from being hacked and controlled from a distance? Companies developing such technologies should make sure they are safe and users should be as vigilant as possible when using them.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"205\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyberattack_Data-breach-512x205.jpg\" alt=\"bioethics\" class=\"wp-image-23442\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyberattack_Data-breach-512x205.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyberattack_Data-breach-768x307.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyberattack_Data-breach-1536x614.jpg 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyberattack_Data-breach.jpg 1920w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.healthitnews.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>3) What to do\nwith biohackers?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cstrong>With the \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Frevolution-access-healthcare-diy-labs-makerspaces\">rise of the maker movement\u003C\u002Fa>, the availability of know-how, raw materials, and an active community, the appearance of “garage solutions” in medicine have multiplied. However, they cannot be considered as unambiguously positive or negative\u003C\u002Fstrong>. Some people have been working out long-term solutions for serious medical conditions outside of the traditional „ivory tower of medical knowledge” as they considered regulation to be too slow compared to innovation. \u003C\u002Fp>\n\n\n\n\u003Cp>Our favorite example is the \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fliving-with-an-artificial-pancreas\u002F\">#wearenotwaiting\nTwitter-movement for patients suffering from diabetes\u003C\u002Fa>. The initiator of the\ncommunity, \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fliving-with-an-artificial-pancreas\u002F\">Dana\nLewis\u003C\u002Fa>, and her husband built a so-called artificial pancreas at home and\nstarted to spread the blueprints and know-how on Twitter to other diabetes\npatients – without waiting for the approval of the FDA or any other agency.\nWhy? Because it works and patients needed it. Dana had been using the device\nfor almost two years by the time the \u003Ca href=\"https:\u002F\u002Fwww.bloomberg.com\u002Fnews\u002Farticles\u002F2016-09-28\u002Fartificial-pancreas-approved-by-fda-is-first-such-device-in-u-s\">US\nFood and Drug Administration finally approved it.\u003C\u002Fa>\u003C\u002Fp>\n\n\n\n\u003Cp>On the other hand, \u003Cstrong>experimenting at home with unapproved or not well-tested technologies is dangerous. Does it mean that patients who will be able to scan themselves, 3D print medications at home or even do genetic engineering should also be allowed to do all these? How should we go about biohackers? Where should the line be drawn between supporting innovation and refusing reckless experimentation?\u003C\u002Fstrong> Do you think that it’s just another far-fetched, non-existent gobbledygook? Have you heard about the biohacker who tried to do CRISPR therapy on himself at his own home? Josiah Zayner \u003Ca href=\"http:\u002F\u002Fwww.buzzfeed.com\u002Fstephaniemlee\u002Fthis-biohacker-wants-to-edit-his-own-dna?utm_term=.rsJBR678M#.evELlvD9p\">injected his arm with DNA encoding for CRISPR\u003C\u002Fa> that could theoretically enhance his muscles—in between taking swigs of Scotch at a live-streamed event during an October conference. Now, \u003Ca href=\"https:\u002F\u002Fwww.theatlantic.com\u002Fscience\u002Farchive\u002F2018\u002F02\u002Fbiohacking-stunts-crispr\u002F553511\u002F\">he believes that wasn’t a good idea\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"256\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FDigital-Tattoos-Look-Like-Biohacking-512x256.jpg\" alt=\"bioethics\" class=\"wp-image-23443\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FDigital-Tattoos-Look-Like-Biohacking-512x256.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FDigital-Tattoos-Look-Like-Biohacking-768x384.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FDigital-Tattoos-Look-Like-Biohacking-1536x768.jpg 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FDigital-Tattoos-Look-Like-Biohacking.jpg 2048w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.dailydot.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>4) What if\nhealthy people turn\u003C\u002Fstrong>\u003Cstrong>ed\u003C\u002Fstrong>\u003Cstrong> to technology?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>As technological innovations in\nthe field of medicine and healthcare multiply day by day, it will be \u003Cstrong>more and more usual to augment our bodies\nwith the help of machines. It makes us faster, stronger or more sensitive to\nthe environment. This means that the boundaries of “human-ness” are stretched.\nHow far can we and should we go?\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>At first, we might \u003Ca href=\"https:\u002F\u002Fieet.org\u002Findex.php\u002FIEET2\u002Fmore\u002Fbjmurphy20160228\">experiment with exoskeletons\u003C\u002Fa> that let warehouse workers lift\nheavy boxes or allow doctors to stand through operations for more than 10\nhours. Those are easily removable mechanic extensions, but what about digital\ntattoos or other implants? What if someone wants to have a brain implant which\nlets him experience sensations better? We surely know that could go wrong –\njust think of \u003Ca href=\"https:\u002F\u002Fwww.imdb.com\u002Ftitle\u002Ftt5058700\u002F?ref_=ttep_ep_cur\">the horrible episode of Black Mirror, Black\nMuseum\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cp>However, digital tattoos could also be removed upon request, we assume, but what if people go one step even further in \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-worlds-most-famous-real-life-cyborgs\">cyborgization\u003C\u002Fa> and request irreversible changes in their bodies? What if people start asking their doctors to replace their healthy limbs for robotic ones because it would let them run faster? What if they start asking for indelible brain chips to get smarter? Currently, you can get a new nose or larger breasts, what would prevent you from getting new muscles or brain implants?\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"292\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyborg-Brain-512x292.jpg\" alt=\"bioethics\" class=\"wp-image-23444\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyborg-Brain-512x292.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyborg-Brain-768x438.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FCyborg-Brain.jpg 1226w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.transpolitica.org\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>5) Biological differences based on inequalities in wealth\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>Both staying healthy and healing\nfrom a condition cost enormous sums of money (well, for the average person, not\nthe Bugatti-buying upper 0.1 percent). Americans are even worse off than other\ndeveloped nations as the US spent 17.8 percent of its GDP on health care in\n2016. Meanwhile, the average spending of 11 high-income countries assessed in a\nreport published in the \u003Ca href=\"https:\u002F\u002Fjamanetwork.com\u002Fjournals\u002Fjama\u002Ffullarticle\u002F2674671\">Journal of the\nAmerican Medical Association\u003C\u002Fa> – Canada, Germany, Australia, the U.K, Japan,\nSweden, France, the Netherlands, Switzerland, Denmark, and the U.S. – was only\n11.5 percent.\u003C\u002Fp>\n\n\n\n\u003Cp>Moreover, the \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fis-crowdfunding-the-grim-future-of-health-insurance\">average\ncost of hospital stays for cancer patients in 2015 was $31,390\u003C\u002Fa>, according\nto U.S. government figures — about half that year’s median household income. In\naddition, \u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC3273528\u002F\">medical\nexpenses are the leading cause of bankruptcy in the U.S, according to a study\nthat\u003C\u002Fa> indicated about 62 percent of personal bankruptcies in 2007 were\nreportedly due to medical bills, even though most of those people had insurance\n— up from about 46 percent in 2001.\u003C\u002Fp>\n\n\n\n\u003Cp>It is even widely \u003Cstrong>reported that the differences in the financial background of people cause visible biological differences. As mentioned above, the \u003Ca href=\"https:\u002F\u002Fwww.healthline.com\u002Fhealth-news\u002Fcan-money-determine-how-long-you-live#2\">gap between the wealthiest and poorest Americans is about 10 years for women and 15 for men\u003C\u002Fa>, so there is a big spread with more affluent people living much longer than the poorer masses. And some are even expecting the widening of the chasm.\u003C\u002Fstrong> With the appearance of direct-to-consumer genetics, (for some) affordable whole-genome sequencing, and later on technologies which can truly augment human capabilities – exoskeletons, implants, digital tattoos, artificial limbs and so on – people with the appropriate means will \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fcan-money-buy-you-longevity-and-health\">live longer and healthier lives\u003C\u002Fa>. \u003Cstrong>How can we mitigate the differences? How can we make innovations more accessible to all kinds of communities? At the same time, how do we prepare society for a time when financial differences lead to biological ones?\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"498\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FPeople-walking-on-the-street-512x498.jpg\" alt=\"bioethics\" class=\"wp-image-23445\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FPeople-walking-on-the-street-512x498.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FPeople-walking-on-the-street-768x746.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FPeople-walking-on-the-street.jpg 1024w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.nytimes.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>6) \u003C\u002Fstrong>\u003Cstrong>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhat-if-we-all-lived-beyond-130-years\">What if we live beyond 130 years\u003C\u002Fa>\u003C\u002Fstrong>\u003Cstrong>?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.theatlantic.com\u002Fmagazine\u002Farchive\u002F2014\u002F10\u002Fwhat-happens-when-we-all-live-to-100\u002F379338\u002F\">Since 1840, life expectancy at birth has\nrisen about three months per year\u003C\u002Fa>. Thus, every year a newborn lives three months longer than those born\nthe previous year. Sweden, which keeps excellent demographic records,\ndocuments female life expectancy at 45 years of age in 1840 and 83 today. \u003Ca href=\"https:\u002F\u002Fwww.telegraph.co.uk\u002Fnews\u002Fscience\u002Fscience-news\u002F11562492\u002FMeet-the-doctor-who-is-convinced-he-will-live-to-150.html\">Experts\neven believe that\u003C\u002Fa> with recent breakthroughs in science and medicine coupled\nwith lifestyle changes, this number could reach far beyond 100 years. Tons of\nethical and philosophical questions appear with that possibility. \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>What would longevity bring for the individual and for society? Does a longer life also go hand in hand with a physically and cognitively stable older age? Do we even want to live longer if we cannot keep our bodies fit for the task? And what about our societies? How would governments, institutions, communities and even our ideas about life itself cope with the changes? \u003C\u002Fstrong>How could we extend our lifespan beyond 100 years of age if the effects of an aging population already strain our societies? If younger generations cannot sustain the social system to provide care for their elders as they are growing older and older, significant structural changes will be necessary. Are we ready for those?\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"257\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F07\u002Faging-man-512x257.png\" alt=\"augment life\" class=\"wp-image-21309\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F07\u002Faging-man-512x257.png 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F07\u002Faging-man-768x385.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F07\u002Faging-man.png 870w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.longevitynetwork.org\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>7) The horrors of\n\u003C\u002Fstrong>\u003Cstrong>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fdisruptive-technologies-bioterrorism\">bioterrorism\u003C\u002Fa>\u003C\u002Fstrong>\u003Cstrong>\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cstrong>The sensitivity of medical and genetic data is mostly due to fears that\nthey could end up in the wrong hands – and for the time being, nothing can be\ndone to counter a potential attack\u003C\u002Fstrong>. Although wrongdoers have to possess\nvery sophisticated skills, so the risks are very low, but there are \u003Cstrong>some experts who worry that precision\nbioterrorism could appear alongside precision medicine and targeted treatments.\nThat would mean that according to genetic markers or any other biological\nmarkers, attackers could choose a target\npopulation and tailor their biological attack according to their genetic\nmake-up or medical data. As you cannot change your genome as you do with your passwords or credit cards,\nanyone can be completely defenseless against such an attack\u003C\u002Fstrong>. Some \u003Ca href=\"https:\u002F\u002Fleapsmag.com\u002Fbad-actors-getting-your-health-data-is-the-fbis-latest-worry\u002F\">FBI\nagents reported\u003C\u002Fa> they worry about healthcare data generated for precision\nmedicine leaving the US vulnerable to such scenarios.\u003C\u002Fp>\n\n\n\n\u003Cp>Alongside with that, hacking of medical devices, complete infrastructures, and systems, manipulation of implants, digital tattoos or robots might leave us utterly assailable. As in the far future, \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhy-people-should-not-fear-digital-health\u002F\">robots on the nanoscale could live in our bloodstream\u003C\u002Fa> or on our eyeballs, some people are also afraid that by using such tiny devices, total surveillance would become feasible – since nothing can remain hidden when there is a robot swimming through your bodily fluids. Let’s do everything in our power to counter these risks and come up with defensive measures as soon as possible.\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"384\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F05\u002Fclose-up-of-male-scientist-hand-inoculating-an-agar-plates-with-bacteria-in-microbiology-lab-512x384.jpg\" alt=\"microbiome testing\" class=\"wp-image-17777\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F05\u002Fclose-up-of-male-scientist-hand-inoculating-an-agar-plates-with-bacteria-in-microbiology-lab-512x384.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F05\u002Fclose-up-of-male-scientist-hand-inoculating-an-agar-plates-with-bacteria-in-microbiology-lab-768x576.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F05\u002Fclose-up-of-male-scientist-hand-inoculating-an-agar-plates-with-bacteria-in-microbiology-lab-334x250.jpg 334w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F05\u002Fclose-up-of-male-scientist-hand-inoculating-an-agar-plates-with-bacteria-in-microbiology-lab.jpg 870w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.genomemag.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>8) \u003C\u002Fstrong>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-future-of-sex-and-sexuality\">Sexuality becoming technological\u003C\u002Fa>\u003Cstrong>\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>Long-distance kisses, hugs, and\ncaresses. Virtual reality porn stars. Sex robots threatening the world’s oldest\nprofession. Technosexuals living with life-sized dolls. At the dawn of a new\nsexual revolution, it’s time to face where technology may take the most intimate\narea of our lives, where will that take humanity, where are our boundaries and\nwhether we want any of it.\u003C\u002Fp>\n\n\n\n\u003Cp>According to the \u003Ca href=\"https:\u002F\u002Ffutureofsex.net\u002FFuture_of_Sex_Report.pdf\">Future of Sex report\nwritten by Jenna Owsianik and Ross Dawson\u003C\u002Fa>, haptic body suits or social\nnetworking sites enhanced with sensual touch interfaces might soon enable fully\nphysical long-distance sex between lovers or hook-up partners thousands of\nkilometers away. Not to mention the possibility of intimate video chats combining\nremote sex devices and holographic partners. \u003Cstrong>The authors even estimate that by 2028, that means in ten years (!),\nover a quarter of young people will have had a long-distance sexual experience.\nBy 2025, 3D-printed body parts could add more realism to the over-the-line sex\ngame. \u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>The other line of innovation includes robots resembling human sex partners. \u003Cstrong>\u003Ca href=\"http:\u002F\u002Fgraphics.bondara.com\u002FFuture_sex_report.pdf\">Some futurists even speculated\u003C\u002Fa> that by 2050, human-robot sex will be more common than human-human sex. But can you imagine having sex with a remote program or a robot? And what if something goes wrong? Do you see such, right now seemingly impossible future news headlines as “Woman Sues Robotics Company for Breaking Her Leg During Sex With Robot”?\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"512\" height=\"288\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F03\u002Fsex-robot-512x288.jpg\" alt=\"Future of Sex\" class=\"wp-image-17357\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F03\u002Fsex-robot-512x288.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F03\u002Fsex-robot-370x208.jpg 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F03\u002Fsex-robot-768x432.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F03\u002Fsex-robot-445x250.jpg 445w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F03\u002Fsex-robot.jpg 770w\" sizes=\"auto, (max-width: 512px) 100vw, 512px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.zdnet.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ch2 class=\"wp-block-heading\">Key Takeaways on Bioethics Issues\u003C\u002Fh2>\n\n\n\n\u003Cp>These questions and bioethics issues cannot be answered by 90-minute-long keynotes and a Q&A session afterward. All kinds of stakeholders need to be brought together by bioethicists to see a vivid palette of opinions, after which, the potential ethical, moral or even legal rules can be set up concerning each of the issues in bioethics. That doesn’t mean only formal discussions – let’s discuss these bioethical topics at home, at the workplace, and on public forums. This way, we can prepare to exploit the advantages technology offers, while keeping the potential dangers at bay.\u003C\u002Fp>\n\n\n\n\u003Cp>And we shall never forget: “Primum non nocere”!\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",{"rendered":60,"protected":16},"\u003Cp>Who owns medical and genetic data? How to regulate gene editing? Where is the boundary of enhancing physical or cognitive human capabilities? What to do with biological differences widening the gap of the haves and have-nots? Could we define where is the boundary to augment life? Will we sue robots or algorithms for medical malpractice? With the constant advancement of technology, unprecedented moral, ethical and legal issues are surfacing. Channeling them into substantial debates will get us closer to their fair solution step by step. Here, we collected the 10 most pressing issues in bioethics.\u003C\u002Fp>\n",6,23447,"closed","","standard",{"_acf_changed":16,"footnotes":64},[68,69,5],511,506,[71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90,91,92],1284,196,830,1285,212,831,1286,246,833,260,904,262,924,289,959,304,996,425,997,1101,1104,194,[],[],[96,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111,112,113],4489,4497,4499,1583,4501,1631,4503,1693,4505,1723,4507,1883,4511,1969,4513,1975,4515,2933,[115,53,116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,145],"post-23437","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-bioethics","category-cyborgization","category-genomics","tag-moral","tag-data-2","tag-sex","tag-debate","tag-dna","tag-sexuality","tag-medical-data","tag-future","tag-cyborgization","tag-genetics","tag-gene-editing","tag-genomics","tag-longevity","tag-innovation","tag-legal","tag-medical","tag-bioethics","tag-technology-2","tag-bioethical","tag-genomic","tag-genetic","tag-cyborg",{"id":62,"alt_text":147,"caption":148,"description":64,"media_type":149,"media_details":150,"post":44,"source_url":190},"bioethics","Source: www.youtube.com","image",{"width":151,"height":152,"file":153,"sizes":154,"image_meta":187},1280,720,"2019\u002F03\u002FFuture-Of-Humanity.jpg",{"medium":155,"large":161,"thumbnail":166,"medium_large":170,"large_old_512x288":171,"thumbnail_old_150x150":176,"medium_old_370x208":178,"medium_large_old_768x432":181,"large_old_512x288_old_512x288":184},{"file":156,"width":157,"height":158,"mime-type":159,"source_url":160},"Future-Of-Humanity-370x208.jpg",370,208,"image\u002Fjpeg","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FFuture-Of-Humanity-370x208.jpg",{"file":162,"width":163,"height":164,"mime-type":159,"source_url":165},"Future-Of-Humanity-768x432.jpg",768,432,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FFuture-Of-Humanity-768x432.jpg",{"file":167,"width":168,"height":168,"mime-type":159,"source_url":169},"Future-Of-Humanity-150x150.jpg",150,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FFuture-Of-Humanity-150x150.jpg",{"file":162,"width":163,"height":164,"mime-type":159,"source_url":165},{"file":172,"width":173,"height":174,"mime-type":159,"source_url":175},"Future-Of-Humanity-512x288.jpg",512,288,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FFuture-Of-Humanity-512x288.jpg",{"file":167,"width":177,"height":177,"mime-type":159,"source_url":169},"150",{"file":156,"width":179,"height":180,"mime-type":159,"source_url":160},"370","208",{"file":162,"width":182,"height":183,"mime-type":159,"source_url":165},"768","432",{"file":172,"width":185,"height":186,"mime-type":159,"source_url":175},"512","288",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188,"keywords":189},"0",[],"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F03\u002FFuture-Of-Humanity.jpg",{"related_posts":192,"related_posts_footer":196,"cta_type":64,"cta_color":64,"subtitle":64,"related_books":16,"key_takeaways":200},[193,194,195],13373,13990,21303,[197,198,199],22549,20686,17353,[201,203,205,207],{"title":202},"\u003Cp>\u003Cstrong>Bioethics examines the ethical, social, and legal dilemmas\u003C\u002Fstrong> that emerge in the fields of biomedicine and biomedical research.\u003C\u002Fp>\n",{"title":204},"\u003Cp>Key bioethical issues include genetic engineering, particularly CRISPR, raising concerns about designer babies and genetic inequality.\u003C\u002Fp>\n",{"title":206},"\u003Cp>Data privacy and security are critical as health data becomes increasingly digitized, posing risks to patient confidentiality.\u003C\u002Fp>\n",{"title":208},"\u003Cp>AI in healthcare presents ethical dilemmas regarding decision-making, bias, and the potential dehumanization of patient care.\u003C\u002Fp>\n",{"yoast_wpseo_title":210,"yoast_wpseo_metadesc":211,"yoast_wpseo_canonical":54},"Top 8 Issues in Bioethics in 2024 - The Medical Futurist","Top Issues & Topics in Bioethics 1) The most important bioethical topic is medical data privacy 2) Bioethical issues of increasing life expectancy 3)",{"self":213,"collection":218,"about":221,"author":224,"replies":227,"version-history":230,"predecessor-version":234,"wp:featuredmedia":238,"wp:attachment":241,"wp:term":244,"curies":259},[214],{"href":215,"targetHints":216},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F23437",{"allow":217},[27],[219],{"href":220},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts",[222],{"href":223},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftypes\u002Fpost",[225],{"embeddable":41,"href":226},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fusers\u002F6",[228],{"embeddable":41,"href":229},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=23437",[231],{"count":232,"href":233},16,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F23437\u002Frevisions",[235],{"id":236,"href":237},60731,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F23437\u002Frevisions\u002F60731",[239],{"embeddable":41,"href":240},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F23447",[242],{"href":243},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=23437",[245,247,250,253,256],{"taxonomy":11,"embeddable":41,"href":246},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=23437",{"taxonomy":248,"embeddable":41,"href":249},"post_tag","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=23437",{"taxonomy":251,"embeddable":41,"href":252},"project_category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=23437",{"taxonomy":254,"embeddable":41,"href":255},"contact_email_category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=23437",{"taxonomy":257,"embeddable":41,"href":258},"yst_prominent_words","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=23437",[260],{"name":39,"href":40,"templated":41},{"id":262,"date":263,"date_gmt":264,"guid":265,"modified":267,"modified_gmt":268,"slug":269,"status":52,"type":53,"link":270,"title":271,"content":273,"excerpt":275,"author":61,"featured_media":277,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":278,"categories":279,"tags":282,"project_category":296,"contact_email_category":297,"yst_prominent_words":298,"class_list":312,"better_featured_image":329,"acf":359,"yoast_meta":376,"_links":379},24598,"2026-03-02T09:05:23","2026-03-02T08:05:23",{"rendered":266},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=24598&_wpnonce=1e9b26d6a0&status=auto-draft&type=post","2026-03-02T09:05:26","2026-03-02T08:05:26","how-much-is-life-worth","https:\u002F\u002Fmedicalfuturist.com\u002Fhow-much-is-life-worth",{"rendered":272},"How Much Is Life Worth?",{"rendered":274,"protected":16},"\n\u003Cp>Multivitamins, drugs, gene therapies, human skin, heart, eyeballs, kidneys, entire dead bodies – everything comes with a price tag. Putting aside the moral questions of why and how the capitalist market prices even our body parts and health, we asked the question of how much life is worth. What is the maximum that you would\u002Fshould pay for a life-saving drug? \u003C\u002Fp>\n\n\n\n\u003Cp>How high is too high a cost if a drug can save 200-300 babies a year from a debilitating illness or death? And ultimately, does the pricing of new technologies, especially gene therapies, enable them to fulfill their promise? \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"How Much Is Your Life Worth? \u002F Episode 17 - The Medical Futurist\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002Fv4ymhGtzcKo?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>There’s a\nprice for everything: butterflies, pieces of moon land, organs\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>The world is a giant supermarket where you find price tags on everything. A rare butterfly \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ebay.co.uk\u002Fsch\u002Fi.html?_from=R40&_trksid=p2334524.m570.l1313&_nkw=butterfly+taxidermy&_sacat=0&LH_TitleDesc=0&_odkw=rare+butterfly+taxidermy&_sop=3\" target=\"_blank\">can cost up to a grand on eBay\u003C\u002Fa>, an acre on the surface of the Moon is \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Flunarembassy.com\u002Fproduct\u002Fbuy-land-on-the-moon\u002F\" target=\"_blank\">available from $34.99\u003C\u002Fa> – although \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.forbes.com\u002Fsites\u002Fquora\u002F2019\u002F01\u002F16\u002Fcan-people-buy-plots-of-land-on-the-moon\u002F?sh=249e010642bc\" target=\"_blank\">we strongly discourage you from actually buying it \u003C\u002Fa> –, and your organs are also for sale. \u003C\u002Fp>\n\n\n\n\u003Cp>If you could harvest \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=yNOsoe44c40\" target=\"_blank\">every organ and chemical in your body\u003C\u002Fa>, you could make a $45 million. But in reality, as Medical Transcription estimates, the average price of a human dead body is more likely to fetch around $550,000 (with a few key body parts driving up the price). \u003C\u002Fp>\n\n\n\n\u003Cp>Contrary to popular belief, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.donoralliance.org\u002Fnewsroom\u002Fdonation-essentials\u002Fcan-you-sell-organs\u002F#:~:text=Selling%20Organs%20in%20the%20United,tissues%20in%20the%20United%20States.\" target=\"_blank\">you are not allowed to sell your organs for transplantation\u003C\u002Fa> purposes in the US. (Nor in any developed country). Although there is\u002Fwas a loophole not specifically banning the sale of bodies and organs for research purposes, the bad news for wannabe millionaires is that the only one making money from their tissues is a \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fnypost.com\u002F2023\u002F06\u002F28\u002Fthe-body-parts-industry-is-boomingwith-heads-going-for-2k\u002F\" target=\"_blank\">cadaver broker\u003C\u002Fa>. And although \u003Ca href=\"https:\u002F\u002Fnfda.org\u002Fnews\u002Fmedia-center\u002Fnfda-news-releases\u002Fid\u002F7475\u002Fcongress-takes-significant-step-to-regulate-body-brokers\" target=\"_blank\" rel=\"noreferrer noopener\">some regulatory adjustments\u003C\u002Fa> are happening, the progress is slow and not yet complete. \u003C\u002Fp>\n\n\n\n\u003Cp>According to the \u003Ca href=\"https:\u002F\u002Fonlinedegreeinfinance.com\u002Fblack-market-body-worth\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">widely used\u003C\u002Fa>, although somewhat hard-to-find-credit-for figures, a heart is worth around $1 million in the US. Livers come in second, worth about $557,000 and kidneys cost about $262,000 each. Not to speak about human skin ($10\u002Finch), stomach ($500), and eyeballs ($1,500 each). \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F03\u002Forgan-design-768x432.png\" alt=\"organ design, tmf, heart, tissue, bioprinting\" class=\"wp-image-41555\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F03\u002Forgan-design-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F03\u002Forgan-design-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F03\u002Forgan-design-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F03\u002Forgan-design.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Unsurprisingly, organs are offered for less on the black market – but you never know where those body parts come from. And although the black market for organs is obviously not very transparent, it has been \u003Ca href=\"https:\u002F\u002Fwww.euronews.com\u002F2022\u002F01\u002F12\u002Fextreme-poverty-drives-afghans-to-sell-vital-organs-to-feed-families\" target=\"_blank\" rel=\"noreferrer noopener\">reported\u003C\u002Fa> numerous times that organ donors in developing countries – most often selling body parts to feed their families – will never see anything like the sums mentioned above, what they get is most likely a thousand dollars or maybe two. And we should also mention that transplantation tourism generates thousands, maybe tens of thousands of \u003Ca href=\"https:\u002F\u002Fwww.interpol.int\u002Fen\u002FNews-and-Events\u002FNews\u002F2021\u002FNorth-and-West-Africa-INTERPOL-report-highlights-human-trafficking-for-organ-removal\" target=\"_blank\" rel=\"noreferrer noopener\">victim donors\u003C\u002Fa> around the world every year.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.researchgate.net\u002Ffigure\u002FAnnual-turnover-of-crime-from-illegal-trafficking-of-vital-organs_tbl1_375245443\" target=\"_blank\">This paper lists a price range\u003C\u002Fa>, stating that illegally harvested\u002Fsold kidneys are sold for $50,000 to $120,000, livers go for $99,000 to $145,000, the price tag of a heart is between $130,000 to $290,000, lungs for $150,000 to $290,000, while a pancreas can cost $110,000 to $140,000.\u003C\u002Fp>\n\n\n\n\u003Cp>The prices of course are completely different if the intended use is not to implant organs, as we can read \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fnypost.com\u002F2023\u002F06\u002F28\u002Fthe-body-parts-industry-is-boomingwith-heads-going-for-2k\u002F\" target=\"_blank\">in this news report\u003C\u002Fa> discussing the criminal case of Cedric Lodge, who \u003Ca href=\"https:\u002F\u002Fnypost.com\u002F2023\u002F06\u002F14\u002Fseven-charged-with-stealing-and-selling-human-remains\u002F\">stole body parts including heads and brains\u003C\u002Fa> that were donated for research at Harvard Medical School, and sold them online. \u003C\u002Fp>\n\n\n\n\u003Cp>Still, the black market for organs is flourishing. Until technology, e.g. 3D bioprinting, doesn’t offer a viable solution for organ donation, it will remain that way – as \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002F3d-bioprinting-overview\" target=\"_blank\" rel=\"noreferrer noopener\">there are too many waiting for organ transplantations\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cblockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n\u003Cp>\u003Cem>\u003Cstrong>This article is one of the most popular ever written by The Medical Futurist, resulting in the team receiving a couple of offers about organs for sale each week. We would like to draw your attention to the fact that we have never been\u002Fand will never be involved in organ sales, and we strongly advise our readers to follow suit. We truly believe in the official organ donor systems of countries and are encouraging everyone to opt-in, as all countries are facing constant organ shortages and the transplantation waiting lists are long. In the unfortunate case of our untimely death, declaring our willingness to become donors can save 8 lives and help a number of others. \u003Cbr>\u003C\u002Fstrong>\u003C\u002Fem>\u003Cbr>\u003Cem>\u003Cstrong>But any black market transaction involving human body parts should have the direst legal consequences for organ brokers, human traffickers, and wealthy organ recipients knowingly tricking people in need to sell out their body parts – often for very little money.\u003C\u002Fstrong>\u003C\u002Fem>\u003C\u002Fp>\n\u003C\u002Fblockquote>\n\n\n\n\u003Cp>So, it seems that your body parts are already labeled with a price tag. Scary, isn’t it? But in terms of the pricing practice, there’s not much difference when it comes to our overall health and life either. The distinction lies in that organs with price tags are not as visible to us as the price of therapies, drugs, or prosthetic body parts. \u003C\u002Fp>\n\n\n\n\u003Cp>Almost every day you pay for your health by buying vitamins, pain medication, or lactose-free milk. The question is how much is the maximum that you would\u002Fshould pay for a life-saving drug? Is it fair to pay for life-saving drugs at all? \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Insulin and polio vaccines were not patented by their inventor\u003C\u002Fstrong>s\u003C\u002Fh2>\n\n\n\n\u003Cp>Medication, especially life-saving drugs, should be available to everyone in need. In an ideal, utopian world, the means of healing people, the instruments for alleviating pain and suffering, and the assets to save lives wouldn’t cost a penny. \u003C\u002Fp>\n\n\n\n\u003Cp>When \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.vox.com\u002F2019\u002F4\u002F3\u002F18293950\u002Fwhy-is-insulin-so-expensive\" target=\"_blank\">inventor Frederick Banting discovered insulin in 1923\u003C\u002Fa>, he \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fthelancet.com\u002Fjournals\u002Flandia\u002Farticle\u002FPIIS2213-8587(17)30115-8\u002Ffulltext\" target=\"_blank\">refused to put his name on the patent\u003C\u002Fa>. He felt it was unethical for a doctor to profit from a discovery that would save lives. Banting’s co-inventors, James Collip, and Charles Best sold the insulin patent to the University of Toronto for a mere $1. They wanted everyone who needed their medication to be able to afford it. But we could list similar examples from Jonas Salk’s \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fdepts.washington.edu\u002Fglobalhealthjustice\u002Fwaivers-on-vaccine-patents-would-save-lives\u002F\" target=\"_blank\">polio vaccine\u003C\u002Fa> to Röntgen’s \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.dpma.de\u002Fenglish\u002Four_office\u002Fpublications\u002Fmilestones\u002Finventionsthatmadehistory\u002Froentgensx-rays\u002Findex.html#:~:text=R%C3%B6ntgen%20was%20considered%20an%20introverted,become%20a%20millionaire%20by%20inheritance).\" target=\"_blank\">X-ray machine\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>These noble gentlemen would definitely turn in their graves if they saw how far we have come since then: if they saw the price tags for certain drugs today or the pricing policies of certain pharma companies. \u003C\u002Fp>\n\n\n\n\u003Cp>Many surely remember \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ftc.gov\u002Fnews-events\u002Fnews\u002Fpress-releases\u002F2024\u002F01\u002Fstatement-second-circuit-order-upholding-pharma-bro-martin-shkrelis-lifetime-ban\" target=\"_blank\">ill-famed Martin Shkreli\u003C\u002Fa> and the outrage he caused when he raised the price of Daraprim, a drug that treats the parasitic infection \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.cdc.gov\u002Fparasites\u002Ftoxoplasmosis\u002F\" target=\"_blank\">toxoplasmosis\u003C\u002Fa> and is used in some cases to treat cancer and AIDS, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nytimes.com\u002F2015\u002F09\u002F21\u002Fbusiness\u002Fa-huge-overnight-increase-in-a-drugs-price-raises-protests.html?_r=0&pagewanted=all\" target=\"_blank\">from $13.50 to $750.00 per pill\u003C\u002Fa> in 2015, which means a more than a 5,000 percent increase! Although a Bloomberg reporter \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.bloomberg.com\u002Fnews\u002Fvideos\u002F2015-09-21\u002Fwhy-turing-increased-price-of-daraprim-over-500-\" target=\"_blank\">suggested\u003C\u002Fa> it should cost around $1 to make, and Shkreli himself acknowledged the drug takes “very little money” to make, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.huffpost.com\u002Fentry\u002Fmartin-shkreli-aids-drug-price-the-same_n_5aa3117fe4b07047bec694cb?guccounter=1&guce_referrer=aHR0cHM6Ly93d3cuZ29vZ2xlLmNvbS8&guce_referrer_sig=AQAAAJ_Hw2-dKv5wlQAxVRIJcWbSTrplnb7wBElDXYp_gQnmAEV2o_GFhiuO96CYx8mPyIF5q1XWOi6hxomEbt91UpJhW49-E0vMWccQHSS2_weonvqQWU5Ff1ZN_hFKPk7aozSu8uB9hctdsiCqu_zprVjlebRIzXaSzlFLhZ4PtI6Q\" target=\"_blank\">the medication still sells for hundreds of dollars\u003C\u002Fa>. Shkreli and his company were able to gouge the price as they acquired the sole rights to the drug’s sale in the U.S. without anyone else offering an alternative. A little side note: Shkreli was \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.npr.org\u002F2022\u002F05\u002F19\u002F1100019063\u002Fpharma-bro-martin-shkreli-been-released-from-prison\" target=\"_blank\">just released from prison\u003C\u002Fa> after he was found guilty of two counts of securities fraud and one count of conspiracy to commit securities fraud. He was sentenced to seven years in prison in 2018.\u003C\u002Fp>\n\n\n\n\u003Cp>Although Shkreli’s example is outrageous, he’s not the only one who did something similar. An article in \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.nejm.org\u002Fdoi\u002Ffull\u002F10.1056\u002FNEJMp1408376\" target=\"_blank\">The New England Journal of Medicine\u003C\u002Fa> focused on how companies buy up the rights to old, inexpensive generic drugs, lock out competitors and raise prices. \u003C\u002Fp>\n\n\n\n\u003Cp>For instance, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nytimes.com\u002F2015\u002F01\u002F15\u002Fopinion\u002Fwhy-drugs-cost-so-much.html\" target=\"_blank\">albendazole, a drug for certain kinds of parasitic infections was approved back in 1996\u003C\u002Fa>. In 2010, its average wholesale cost was $5.92 per day, but by 2013, it rose to $119.58. Perhaps the most concerning piece of news was, though, that the price of insulin has risen uncontrollably in the United States. The cost of the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fjamanetwork.com\u002Fjournals\u002Fjamainternalmedicine\u002Ffullarticle\u002F2717498\" target=\"_blank\">four most popular types of insulin\u003C\u002Fa> has tripled over the past decade, and the out-of-pocket prescription costs patients now face have doubled. By 2016, the average price per month \u003Ca href=\"https:\u002F\u002Fwww.nytimes.com\u002F2019\u002F04\u002F03\u002Fhealth\u002Fdrug-prices-insulin-express-scripts.html\">rose to $450\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cp>Fortunately, governmental regulation started to take note and act on it. The \u003Ca href=\"https:\u002F\u002Fwww.govinfo.gov\u002Fapp\u002Fdetails\u002FBILLS-117hr6833pcs\u002Fsummary\">Affordable Insulin Now Act\u003C\u002Fa> \u003Ca href=\"https:\u002F\u002Fwww.pharmaceutical-technology.com\u002Fanalysis\u002Finsulin-pricing-reform-senate\u002F\">was supported by Congress\u003C\u002Fa> in 2022 and \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fedition.cnn.com\u002F2024\u002F01\u002F01\u002Fpolitics\u002Finsulin-price-cap\u002Findex.html\" target=\"_blank\">was approved in 2024\u003C\u002Fa> introducing a $35 cap on insulin prices\u002Fmonth nationwide.  \u003C\u002Fp>\n\n\n\n\u003Cp>It’s certain that without efficient regulatory intervention, pharma companies won’t change their exaggerated pricing policies in the U.S. It is visible, for example, that in Western European countries where \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Ftheconversation.com\u002Fwhy-the-us-has-higher-drug-prices-than-other-countries-111256\" target=\"_blank\">price controls are in place, medication costs are lower\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Rare diseases, unique therapies, unspeakable prices\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>However, the problem is not just the increase in the price of generic drugs such as insulin, but also the incredibly high prices of new therapies and treatment options for rare diseases. \u003C\u002Fp>\n\n\n\n\u003Cp>The most expensive drug on the market in May 2024 \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fda.gov\u002Fnews-events\u002Fpress-announcements\u002Ffda-approves-first-gene-therapy-children-metachromatic-leukodystrophy\" target=\"_blank\">was Lenmeldy\u003C\u002Fa>, a gene therapy used to treat types of \u003Ca href=\"https:\u002F\u002Fwww.drugs.com\u002Fcondition\u002Fmetachromatic-leukodystrophy.html\">metachromatic leukodystrophy\u003C\u002Fa> in children. A single dose costs $4,25 million, and it works by helping the body make the ARSA enzyme to help stop the progression of MLD, it does this using the patient’s own stem cells that have been modified. Lenmeldy is given as a one-time infusion. The FDA approved this drug in March 2024. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F12\u002Ftmf_article_393_CRISPR_gene_editing-768x432.png\" alt=\"gene editing, CRISPR, DNA\" class=\"wp-image-54001\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F12\u002Ftmf_article_393_CRISPR_gene_editing-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F12\u002Ftmf_article_393_CRISPR_gene_editing-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F12\u002Ftmf_article_393_CRISPR_gene_editing.png 1520w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Another well-known example is \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fda.gov\u002Fnews-events\u002Fpress-announcements\u002Ffda-approves-innovative-gene-therapy-treat-pediatric-patients-spinal-muscular-atrophy-rare-disease\" target=\"_blank\">Zolgensma\u003C\u002Fa>, a gene therapy for a rare childhood disease, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fghr.nlm.nih.gov\u002Fcondition\u002Fspinal-muscular-atrophy\" target=\"_blank\">spinal muscular atrophy (SMA)\u003C\u002Fa> caused by a single gene. At the moment, it costs $2.1 million per patient. This experimental therapy means \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.npr.org\u002Fsections\u002Fhealth-shots\u002F2019\u002F05\u002F24\u002F725404168\u002Fat-2-125-million-new-gene-therapy-is-the-most-expensive-drug-ever?t=1566983817416\" target=\"_blank\">infusing the patient with genetically modified viruses carrying healthy copies of the gene needed\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cp>Other revolutionary gene therapies are underway – and many fear that while they have the potential to eliminate lethal childhood diseases and other rare conditions, no one’s going to pay for them as their price is set too high.\u003C\u002Fp>\n\n\n\n\u003Cp>Are the “\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.drugs.com\u002Farticle\u002Ftop-10-most-expensive-drugs.html\" target=\"_blank\">most expensive therapies ever\u003C\u002Fa>” really the most expensive ever? \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fpubmed.ncbi.nlm.nih.gov\u002F33908277\u002F#:~:text=At%20an%20upfront%20price%20of,characterization%20raises%20important%20methodological%20and\" target=\"_blank\">This study\u003C\u002Fa> tried to assess the values of these therapies and came to the conclusion that economic evaluation of novel therapies requires careful comparison of lifetime cost and benefits vs standard of care, including adjustments for pricing distortions. We also have to note though that the study was funded by Novartis Gene Therapies Inc., so we might have to wait for more research before drawing a final conclusion. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Why are gene therapies so highly priced?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>The pricing of medication and therapies is often way too complex and sometimes, as in the above cases of insulin and Daraprim, it seems to be way too arbitrary. \u003Ca href=\"https:\u002F\u002Fwww.nytimes.com\u002F2019\u002F08\u002F25\u002Fhealth\u002Fdrug-prices-rare-diseases.html\" target=\"_blank\" rel=\"noreferrer noopener\">Experts say\u003C\u002Fa> that now that cheaper generic drugs account for about 90 percent of all prescriptions filled in the United States, pharmaceutical companies are turning to rare disease treatments and gene therapies as their next profit engine, with major companies like Pfizer and Novartis investing in drugs for tiny pools of patients. \u003C\u002Fp>\n\n\n\n\u003Cp>The question arises naturally: should a premium be paid for the treatment of diseases that are considered ‘rare’? What should be a reasonable price for what is called an orphan drug? Is it a viable method that rare disease drugs are priced based on a patient’s weight – meaning that a prescription for an adult costs many times more than one for a child? Could it be the solution when \u003Ca href=\"https:\u002F\u002Fwww.bloomberg.com\u002Fnews\u002Farticles\u002F2019-04-07\u002Fgene-therapy-was-hailed-as-a-revolution-then-came-the-bill\" target=\"_blank\" rel=\"noreferrer noopener\">therapies are paid for in installments\u003C\u002Fa>?\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F04\u002Ftmf_article_409_b-768x432.png\" alt=\"\" class=\"wp-image-55697\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F04\u002Ftmf_article_409_b-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F04\u002Ftmf_article_409_b-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F04\u002Ftmf_article_409_b-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F04\u002Ftmf_article_409_b-2048x1152.png 2048w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>When \u003Ca href=\"https:\u002F\u002Fdailynous.com\u002F2015\u002F09\u002F28\u002Fphilosophers-on-drug-prices\u002F\">asked about\u003C\u002Fa> fair pricing on drugs, Samia Hurst bioethicist said that “making a profit from finding, developing, and selling pharmaceuticals is legitimate, although we were never truly clear about what made it so. Perhaps we approve of this profit because we believe that the effort and creativity involved in bringing a new drug to the market deserve to be paid for. Perhaps we consider that the manufacture of a drug also merits payment. Perhaps we are not considering merit at all, but looking to the consequences: we want to incentivize the development of new therapeutic advances. Perhaps we want to guarantee that access to needed medical therapies is kept up by the profit motive”. That all could be a drive behind allowing pharma companies to ask for fair profit margins put above the costs of research and development.\u003C\u002Fp>\n\n\n\n\u003Cp>Also, \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fdailynous.com\u002F2015\u002F09\u002F28\u002Fphilosophers-on-drug-prices\u002F\" target=\"_blank\">political philosopher Matt Zwolinski argues\u003C\u002Fa> that those high prices are not only necessary to recoup the cost spent researching and developing that drug but also the hundreds of other drugs that never made it to market. Charging a price that’s well above the “marginal cost of production” is the only way companies can make a normal level of profit over the long run, and therefore the only way to ensure that society gets the new drugs it needs.\u003C\u002Fp>\n\n\n\n\u003Cp>Moreover, if we compare \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fprecision-medicine-best-hope-fight-cancer\" target=\"_blank\">personalised thera\u003C\u002Fa>pies with generic solutions that have been used up until now, their advantage is clear. On the one hand, they offer an efficient solution – and heal patients from diseases that were untreatable before, and on the other hand, they are much more cost-efficient in the long run when looking at the entire society. Thus, the development of personalised treatment solutions is definitely the way forward – although companies should come up with better options for payment.\u003C\u002Fp>\n\n\n\n\u003Cp>Ultimately, the \u003Ca style=\"\" href=\"https:\u002F\u002Fpubmed.ncbi.nlm.nih.gov\u002F22789042\u002F\">Human Rights Guidelines for Pharmaceutical Companies in Relation to Access to Medicines\u003C\u002Fa> specify that “companies must do all they reasonably can to ensure that medicines are available in sufficient quantities in the countries where they are needed.” \u003C\u002Fp>\n\n\n\n\u003Cp>They also suggest that companies are \u003Ca href=\"http:\u002F\u002Fdailynous.com\u002F2015\u002F09\u002F28\u002Fphilosophers-on-drug-prices\u002F\">obligated to contribute to the development of drugs for neglected diseases\u003C\u002Fa>. Thus, companies must make sure the drugs they produce are accessible to all patient groups – not just rich patients or those in developed countries, driving others to desperate solutions such as \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fis-crowdfunding-the-grim-future-of-health-insurance\">crowdfunding\u003C\u002Fa> or not going to the hospital for treatment at all. Only then could gene therapies and other revolutionary healing methods fulfill their potential in making patients’ lives better.\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs?hl=en&cc_lang_pref=en&cc=1\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",{"rendered":276,"protected":16},"\u003Cp>We asked the question how much life is worth? A heart can be purchased for $1000000. Livers are worth about $557000 & kidneys cost about $262000.\u003C\u002Fp>\n",24604,{"_acf_changed":16,"footnotes":64},[68,280,281,5],500,490,[283,284,87,285,286,287,288,80,289,88,290,291,292,293,294,295],994,229,253,1154,255,1455,1456,1457,1458,1459,1460,846,217,[],[],[299,300,301,107,302,303,304,305,306,307,308,309,310,311],1613,3271,1633,2215,2217,2219,2227,2233,2235,1599,2239,1609,2241,[313,53,116,117,118,119,120,121,314,315,123,316,317,140,318,319,320,321,133,322,141,323,324,325,326,327,328],"post-24598","category-biotechnology","category-future-of-pharma","tag-life","tag-ethics","tag-gene","tag-medication","tag-gene-therapy","tag-rare-disease","tag-daraprim","tag-drug-price","tag-pricing-policy","tag-rare-disorder","tag-cost","tag-insulin","tag-drug",{"id":277,"alt_text":330,"caption":64,"description":64,"media_type":149,"media_details":331,"post":262,"source_url":358},"life worth",{"width":332,"height":333,"file":334,"sizes":335,"image_meta":357},1920,1080,"2019\u002F08\u002F104_How-much-is-life-worth.png",{"medium":336,"large":340,"thumbnail":343,"medium_large":346,"1536x1536":347,"2048x2048":352},{"file":337,"width":179,"height":180,"mime-type":338,"source_url":339},"104_How-much-is-life-worth-370x208.png","image\u002Fpng","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F08\u002F104_How-much-is-life-worth-370x208.png",{"file":341,"width":182,"height":183,"mime-type":338,"source_url":342},"104_How-much-is-life-worth-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F08\u002F104_How-much-is-life-worth-768x432.png",{"file":344,"width":177,"height":177,"mime-type":338,"source_url":345},"104_How-much-is-life-worth-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F08\u002F104_How-much-is-life-worth-150x150.png",{"file":341,"width":182,"height":183,"mime-type":338,"source_url":342},{"file":348,"width":349,"height":350,"mime-type":338,"source_url":351},"104_How-much-is-life-worth-1536x864.png","1536","864","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F08\u002F104_How-much-is-life-worth-1536x864.png",{"file":353,"width":354,"height":355,"mime-type":338,"source_url":356},"104_How-much-is-life-worth-2048x1152.png","2048","1152","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F08\u002F104_How-much-is-life-worth-2048x1152.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F08\u002F104_How-much-is-life-worth-scaled.png",{"related_posts":16,"related_posts_footer":360,"cta_type":364,"cta_color":64,"subtitle":64,"related_books":365,"key_takeaways":369},[361,362,363],55683,55459,55791,"subscribe",[366,367,368],24765,52203,55605,[370,372,374],{"title":371},"\u003Cp>If you try hard enough, you can put a price tag on everything, from rare butterflies to kidneys and human hearts, everyday and rare treatments and ultimately human health\u003C\u002Fp>\n",{"title":373},"\u003Cp>While there is a serious shortage of available donor organs all over the world, the illegal organ trade can not be stopped, illegal transplants being a trillion-dollar trade globally.\u003C\u002Fp>\n",{"title":375},"\u003Cp>We need to raise a range of ethical, financial, and philosophical questions when trying to answer the question: how much is life worth.\u003C\u002Fp>\n",{"yoast_wpseo_title":377,"yoast_wpseo_metadesc":378,"yoast_wpseo_canonical":270},"How Much Is Life Worth? - The Medical Futurist - Bioethics","We asked the question How Much is Life Worth? A heart can be purchased for $1000000. Livers are worth about $557000 & kidneys cost about $262000",{"self":380,"collection":385,"about":387,"author":389,"replies":391,"version-history":394,"predecessor-version":398,"wp:featuredmedia":402,"wp:attachment":405,"wp:term":408,"curies":419},[381],{"href":382,"targetHints":383},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F24598",{"allow":384},[27],[386],{"href":220},[388],{"href":223},[390],{"embeddable":41,"href":226},[392],{"embeddable":41,"href":393},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=24598",[395],{"count":396,"href":397},41,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F24598\u002Frevisions",[399],{"id":400,"href":401},58531,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F24598\u002Frevisions\u002F58531",[403],{"embeddable":41,"href":404},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F24604",[406],{"href":407},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=24598",[409,411,413,415,417],{"taxonomy":11,"embeddable":41,"href":410},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=24598",{"taxonomy":248,"embeddable":41,"href":412},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=24598",{"taxonomy":251,"embeddable":41,"href":414},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=24598",{"taxonomy":254,"embeddable":41,"href":416},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=24598",{"taxonomy":257,"embeddable":41,"href":418},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=24598",[420],{"name":39,"href":40,"templated":41},{"id":422,"date":423,"date_gmt":424,"guid":425,"modified":427,"modified_gmt":428,"slug":429,"status":52,"type":53,"link":430,"title":431,"content":433,"excerpt":435,"author":61,"featured_media":437,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":438,"categories":439,"tags":443,"project_category":451,"contact_email_category":454,"yst_prominent_words":455,"class_list":458,"better_featured_image":472,"acf":502,"yoast_meta":517,"_links":520},57335,"2026-02-17T14:14:59","2026-02-17T13:14:59",{"rendered":426},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=57335&_wpnonce=16aa64a13b&status=auto-draft&type=post","2026-02-17T14:15:00","2026-02-17T13:15:00","gene-therapys-giant-leap-from-rare-conditions-to-common-cures","https:\u002F\u002Fmedicalfuturist.com\u002Fgene-therapys-giant-leap-from-rare-conditions-to-common-cures",{"rendered":432},"Gene Therapy’s Giant Leap: From Rare Conditions To Common Cures",{"rendered":434,"protected":16},"\n\u003Cp>Gene therapy is a medical field that aims to treat or prevent diseases by modifying the genes within a patient’s cells. It often uses vectors, typically viruses, to deliver therapeutic genes into target cells. The concept of gene therapy is to fix a genetic problem at its source. This quickly developing medical segment brought so many exciting novelties in the past year (even \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fda.gov\u002Fnews-events\u002Fpress-announcements\u002Ffda-approves-first-gene-therapy-treat-adults-metastatic-synovial-sarcoma\" target=\"_blank\">in the past few days\u003C\u002Fa>) that we wanted to provide an overview of the most important milestones from the recent period. \u003C\u002Fp>\n\n\n\n\u003Cp>Let’s start with a short overview of what gene therapy is and what the basics are worth knowing about these cutting-edge treatments. \u003C\u002Fp>\n\n\n\n\u003Cp>Gene therapy has various forms, including \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Gene replacement\u003C\u002Fstrong>: for diseases caused by a single faulty gene, gene therapy can provide a working copy of that gene to restore normal function. An example of this is Luxturna, which treats Leber’s congenital amaurosis, a form of inherited blindness, by providing a functional copy of the RPE65 gene.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Gene augmentation\u003C\u002Fstrong>: this broader category involves adding new genes to cells, either to replace faulty ones or to enhance cellular functions. An example is Zolgensma, which treats spinal muscular atrophy (SMA) by adding a functional copy of the SMN1 gene to replace the missing or nonfunctional one, thereby restoring muscle function.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Gene silencing\u003C\u002Fstrong>: for diseases caused by overactive genes, therapy can “silence” those genes to reduce their harmful effects. An example is Onpattro (Patisiran), which treats hereditary transthyretin-mediated amyloidosis by using RNA interference to silence the TTR gene, reducing the production of the harmful amyloid protein.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Gene editing\u003C\u002Fstrong>: technologies like \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-state-of-crispr-clinical-trials-and-their-future-potentials\" target=\"_blank\" rel=\"noreferrer noopener\">CRISPR\u003C\u002Fa> allow scientists to edit the genetic code to correct mutations. Casgevy is the first approved CRISPR-based therapy, receiving regulatory approval in 2023 for sickle cell disease. \u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Prosthetic gene therapy\u003C\u002Fstrong> aims to enable cells to take on new functions that they do not naturally perform. One example is vision restoration gene therapy, which aims to restore vision in patients with end-stage retinal diseases by delivering light-sensitive proteins into the remaining cells of the retina, rendering them light-sensitive and enabling them to signal visual information to the brain. No approved therapies exist yet, but promising research is underway.\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg decoding=\"async\" src=\"https:\u002F\u002Flh7-rt.googleusercontent.com\u002Fdocsz\u002FAD_4nXc8RwA75w3xXlAXYQoC3InSuZxNfk09DC7VDiDo-7-W-GlUsmicJkyh4QbU9KafKhub6SQH4MM6j2KwC12tqJnSkYrRN5aIBOKjfmDTuVC2h9dJTGopnpqjvTwG8EZnXSUDltaA8hLlTwSPvr6kayA7vzAT?key=E7Oc6LH-jUx-IzXAjsJ4HQ\" alt=\"\"\u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The method of delivery can be categorised into two main approaches: \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>In \u003Cstrong>in vivo gene therapy\u003C\u002Fstrong>, a vector (typically, a virus) is introduced to the patient, which then achieves the desired biological effect by passing the genetic material (e.g. for a missing protein) into the patient’s cells.  \u003C\u002Fli>\n\n\n\n\u003Cli>In \u003Cstrong>ex vivo gene therapies\u003C\u002Fstrong>, such as CAR-T therapeutics, the patient’s own cells (autologous) or healthy donor cells (allogeneic) are modified outside the body (hence, ex vivo) using a vector to express a particular protein.\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cp>Gene therapy is classified into two types by the type of cell it affects: \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Somatic cell therapy (SCGT) \u003C\u002Fstrong>affects non-reproductive cells and is not inherited by offspring. \u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Germline gene therapy (GGT)\u003C\u002Fstrong> affects reproductive cells and can be passed down. Countries like Australia, Canada, Germany, Israel, Switzerland, and the Netherlands prohibit GGT in humans due to ethical concerns.\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cp>The delivery of DNA into cells can be accomplished by multiple methods: \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Viral vectors\u003C\u002Fstrong>: recombinant viruses, often preferred for their efficiency and specificity\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Non-viral methods\u003C\u002Fstrong>: naked DNA or DNA complexes, offering lower immunogenicity\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cblockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n\u003Cp>It is impossible to paint a comprehensive picture of this complex field without writing a novel, so \u003Cstrong>we decided to focus only on the latest developments\u003C\u002Fstrong>, to show the most recent updates and peek into the near future, estimating the immediate progress.\u003C\u002Fp>\n\u003C\u002Fblockquote>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">The first regulatory approval in the world for a CRISPR-based therapy\u003C\u002Fh2>\n\n\n\n\u003Cp>Casgevy, from Vertex Pharmaceuticals and CRISPR Therapeutics was approved in November 2023 in the United Kingdom for treating the blood disorders sickle cell disease and beta thalassemia for patients 12 and older. This is a one-time treatment, and \u003Ca href=\"https:\u002F\u002Fmedcitynews.com\u002F2023\u002F11\u002Fu-k-is-first-to-approve-a-crispr-based-therapy-covering-two-blood-disorders\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">here is how it works\u003C\u002Fa>: \u003C\u002Fp>\n\n\n\n\u003Cp>“Casgevy is made by collecting a patient’s stem cells from the bone marrow. In a lab, CRISPR is used to edit a gene in those cells to produce high levels of fetal hemoglobin. Before these modified stem cells are administered, a conditioning regimen is required to kill the remaining cells in a patient that are making faulty hemoglobin. Infused into the patient, the modified stem cells make their way to the bone marrow.\u003C\u002Fp>\n\n\n\n\u003Cp>Patients may need to remain hospitalized for at least a month while those cells take up residence in the bone marrow and start producing red blood cells that incorporate fetal hemoglobin.”\u003C\u002Fp>\n\n\n\n\u003Cp>The \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fda.gov\u002Fnews-events\u002Fpress-announcements\u002Ffda-approves-first-gene-therapies-treat-patients-sickle-cell-disease\" target=\"_blank\">FDA approval\u003C\u002Fa> came about a month later, also clearing Lyfgenia, which uses a lentiviral vector for genetic modification and is approved for the treatment of patients 12 years of age and older with sickle cell disease and a history of vaso-occlusive events. \u003C\u002Fp>\n\n\n\n\u003Cp>The latest \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fda.gov\u002Fnews-events\u002Fpress-announcements\u002Ffda-approves-first-gene-therapy-treat-adults-metastatic-synovial-sarcoma\" target=\"_blank\">FDA-approved treatment is Tecelra\u003C\u002Fa>, a gene therapy indicated for the treatment of adults with unresectable or metastatic synovial sarcoma. Tecelra is also the first FDA-approved T cell receptor (TCR) gene therapy, administered as a single intravenous dose.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">A baby born deaf can hear after breakthrough gene therapy\u003C\u002Fh2>\n\n\n\n\u003Cp>Opal Sandy was born with a rare genetic condition, auditory neuropathy, and was completely deaf due to the disruption of nerve impulses traveling from the inner ear to the brain.\u003C\u002Fp>\n\n\n\n\u003Cp>She was the first patient treated in a \u003Ca href=\"https:\u002F\u002Fwww.senselab.neurosciences.medschl.cam.ac.uk\u002Four-research\u002Fchord-gene-therapy-clinical-trial\" target=\"_blank\" rel=\"noreferrer noopener\">global gene therapy trial\u003C\u002Fa>, and within four weeks of having the gene therapy infusion to her right ear, \u003Ca href=\"https:\u002F\u002Fwww.cuh.nhs.uk\u002Fnews\u002Fbaby-born-deaf-can-hear-after-breakthrough-gene-therapy\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Opal responded to sound\u003C\u002Fa>, even with the cochlear implant in her left ear switched off. The 24-week checkup confirmed close to normal hearing levels for soft sounds, such as whispering, in her treated ear.\u003C\u002Fp>\n\n\n\n\u003Cp>According to the reports, at the age of 18 months, the baby girl was able to respond to her parents’ voices and started saying basic words, such as “Dada” and “bye-bye.”\u003C\u002Fp>\n\n\n\n\u003Cp>Along very similar lines, \u003Ca href=\"https:\u002F\u002Fwww.thelancet.com\u002Fjournals\u002Flancet\u002Farticle\u002FPIIS0140-6736(23)02874-X\u002Fabstract\" target=\"_blank\" rel=\"noreferrer noopener\">a research team from China reported\u003C\u002Fa> that six kids with a type of hereditary deafness received an experimental gene therapy injected into one of their ears. Five out of the six children experienced significant improvements in their hearing, with their auditory thresholds improving by 40-57 decibels. This enhancement in hearing ability also led to improved speech perception in these children.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Small-scale human trial shows promise in lowering cholesterol\u003C\u002Fh2>\n\n\n\n\u003Cp>Following the previous, existing use cases of gene therapies, it is worth discussing what potential we see in this area. The next examples are not patient-ready innovations yet, but show how versatile help we can expect from these technologies.\u003C\u002Fp>\n\n\n\n\u003Cp>While \u003Ca href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fd41586-023-03543-z\" target=\"_blank\" rel=\"noreferrer noopener\">the VERVE-101\u003C\u002Fa> trial only included 10 participants with heterozygous familial hypercholesterolemia (HeFH), which causes lifelong high levels of low-density lipoprotein (LDL) cholesterol, the \u003Ca href=\"https:\u002F\u002Fwww.vervetx.com\u002Fsites\u002Fdefault\u002Ffiles\u002F2023-11\u002FVerve_AHA_2023_LBS_for%20website.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">interim results are promising\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg decoding=\"async\" src=\"https:\u002F\u002Flh7-rt.googleusercontent.com\u002Fdocsz\u002FAD_4nXfUVm0t7UGDQv074N14SXAfbAngwdUCJX8eOtjHszpPdr2hSKQJsZ2YnPf2JK6IDS7B34LJj_A-qrTcHjAgsMXPksGTVj5AckdwEISTMq66k2vVwVPTgr3R0R7g-PXNweoiMplPaakS1DLXI5cDEnXXk5xR?key=E7Oc6LH-jUx-IzXAjsJ4HQ\" alt=\"\"\u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The trial used a treatment called VERVE-101, which involves a one-time injection that permanently deactivates the PCSK9 gene in the liver. This gene is known to regulate LDL levels, a significant contributor to heart disease. By turning off PCSK9, the treatment successfully reduced LDL cholesterol levels by up to 55% in participants.\u003C\u002Fp>\n\n\n\n\u003Cp>This was a Phase-1 trial so there is still a long way to go, but imagine the possibilities of having a one-time injection that could get rid of high cholesterol for good! \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Gene therapy relieves back pain and repairs damaged discs in mice\u003C\u002Fh2>\n\n\n\n\u003Cp>Here is \u003Ca href=\"https:\u002F\u002Fnews.osu.edu\u002Fgene-therapy-relieves-back-pain-repairs-damaged-disc-in-mice\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">an interesting new area\u003C\u002Fa> for gene therapies! If you suffer from back pain due to a damaged disc, this might be great news for you. It seems it works in animal studies:\u003C\u002Fp>\n\n\n\n\u003Cp>“Scientists engineered nanocarriers using mouse connective-tissue cells called fibroblasts as a model of skin cells and loaded them with genetic material for a protein key to tissue development.\u003C\u002Fp>\n\n\n\n\u003Cp>The team injected a solution containing the carriers into damaged discs in mice at the same time the back injury occurred.”\u003C\u002Fp>\n\n\n\n\u003Cp>It’s one thing that gene therapies have been proven to be effective in certain genetic conditions (even though they are incredibly expensive), but how about relieving back pain? \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">The costs will determine the success and accessibility\u003C\u002Fh2>\n\n\n\n\u003Cp>As the examples above show, we have seen incredible progress in gene therapies in the past decade, with many exciting results emerging just in the last year. From treating rare genetic disorders to targeting more common conditions, the potential of gene therapy has expanded remarkably. Looking ahead, the future of gene therapy is even more exciting, with applications extending into broader fields that impact millions or even hundreds of millions of people. \u003C\u002Fp>\n\n\n\n\u003Cp>However, these treatments are still incredibly, frighteningly expensive, so we cannot expect widespread use in the short term. \u003C\u002Fp>\n\n\n\n\u003Cp>The\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.bloomberg.com\u002Fnews\u002Farticles\u002F2024-03-20\u002Fworld-s-most-expensive-drug-is-now-4-25-million-gene-therapy?embedded-checkout=true\" target=\"_blank\"> world’s most expensive drug\u003C\u002Fa> is the FDA-approved gene therapy, Libmeldy, with a staggering $4.25 million for a one-time treatment. Hemgenix, with its $3.5 million price tag was the record holder before, but gene therapies like Skysona ($3 million)and Zynteglo ($2.8 million) are not cheap either. Zolgensma has a price of $2.1 million per one-time treatment. Compared to these Luxturna seems like a bargain at $425,000 per eye \u002F $850,000 per patient. The price of the latest approved gene therapy, Tecelra, has a list price of $727,000 for the one-time treatment. \u003C\u002Fp>\n\n\n\n\u003Cp>This is why research targeting more common conditions is particularly intriguing. By focusing on treatments for widespread health issues, we may eventually develop therapies that are accessible and affordable for everyone. \u003C\u002Fp>\n",{"rendered":436,"protected":16},"\u003Cp>Gene therapy can potentially cure cancer, genetic defects or infectious diseases, but the million-dollar pricetags are a major problem. We have reason for optimism. \u003C\u002Fp>\n",57337,{"_acf_changed":16,"footnotes":64},[440,441,5,442],7079,521,489,[444,445,446,447,81,448,449,287,450],7979,7981,570,7983,7985,7987,7977,[452,453],950,951,[],[456,302,457],1841,2947,[459,53,116,117,118,119,120,460,461,123,462,463,464,465,466,134,467,468,320,469,470,471],"post-57335","category-tmf","category-future-medicine","category-personalized-medicine","tag-luxturna","tag-zolgensma","tag-crispr","tag-onpattro","tag-casgevy","tag-car-t","tag-gene-replacement","project_category-medical-professionals","project_category-patients",{"id":437,"alt_text":473,"caption":64,"description":64,"media_type":149,"media_details":474,"post":422,"source_url":501},"gene therapy",{"width":475,"height":476,"file":477,"filesize":478,"sizes":479,"image_meta":499},1820,1024,"2024\u002F08\u002Ftmf_article_426-01.png",560115,{"medium":480,"large":484,"thumbnail":488,"medium_large":492,"1536x1536":493},{"file":481,"width":157,"height":158,"mime-type":338,"filesize":482,"source_url":483},"tmf_article_426-01-370x208.png",44637,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01-370x208.png",{"file":485,"width":163,"height":164,"mime-type":338,"filesize":486,"source_url":487},"tmf_article_426-01-768x432.png",129136,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01-768x432.png",{"file":489,"width":168,"height":168,"mime-type":338,"filesize":490,"source_url":491},"tmf_article_426-01-150x150.png",20793,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01-150x150.png",{"file":485,"width":163,"height":164,"mime-type":338,"filesize":486,"source_url":487},{"file":494,"width":495,"height":496,"mime-type":338,"filesize":497,"source_url":498},"tmf_article_426-01-1536x864.png",1536,864,356993,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01-1536x864.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188,"keywords":500},[],"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2024\u002F08\u002Ftmf_article_426-01.png",{"cta_type":364,"cta_color":64,"related_posts_footer":503,"related_posts":16,"related_books":507,"subtitle":64,"key_takeaways":510},[504,505,506],57249,57079,14811,[367,508,509],31417,24759,[511,513,515],{"title":512},"\u003Cp>\u003Cspan style=\"font-weight: 400;\">Gene therapy offers fantastic solutions for genetically derived diseases and shows potential in fighting cancer and certain infectious diseases. \u003C\u002Fspan>\u003C\u002Fp>\n",{"title":514},"\u003Cp>\u003Cspan style=\"font-weight: 400;\">The field is advancing at an astonishing pace. We wanted to highlight the many exciting breakthroughs research labs reported over the past year.\u003C\u002Fspan>\u003C\u002Fp>\n",{"title":516},"\u003Cp>\u003Cspan style=\"font-weight: 400;\">While these treatments are currently prohibitively expensive, there is hope for change. \u003C\u002Fspan>\u003C\u002Fp>\n",{"yoast_wpseo_title":518,"yoast_wpseo_metadesc":519,"yoast_wpseo_canonical":430},"Gene Therapy's Giant Leap: From Rare Conditions To Common Cures","Gene therapy could be a game-changer, but the million-dollar price tags are a major problem. However, with new research, we can hope it becomes affordable.",{"self":521,"collection":526,"about":528,"author":530,"replies":532,"version-history":535,"predecessor-version":539,"wp:featuredmedia":543,"wp:attachment":546,"wp:term":549,"curies":560},[522],{"href":523,"targetHints":524},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F57335",{"allow":525},[27],[527],{"href":220},[529],{"href":223},[531],{"embeddable":41,"href":226},[533],{"embeddable":41,"href":534},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=57335",[536],{"count":537,"href":538},10,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F57335\u002Frevisions",[540],{"id":541,"href":542},57379,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F57335\u002Frevisions\u002F57379",[544],{"embeddable":41,"href":545},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F57337",[547],{"href":548},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=57335",[550,552,554,556,558],{"taxonomy":11,"embeddable":41,"href":551},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=57335",{"taxonomy":248,"embeddable":41,"href":553},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=57335",{"taxonomy":251,"embeddable":41,"href":555},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=57335",{"taxonomy":254,"embeddable":41,"href":557},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=57335",{"taxonomy":257,"embeddable":41,"href":559},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=57335",[561],{"name":39,"href":40,"templated":41},{"id":563,"date":564,"date_gmt":565,"guid":566,"modified":568,"modified_gmt":569,"slug":570,"status":52,"type":53,"link":571,"title":572,"content":574,"excerpt":576,"author":61,"featured_media":578,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":579,"categories":580,"tags":581,"project_category":582,"contact_email_category":583,"yst_prominent_words":584,"class_list":593,"better_featured_image":595,"acf":621,"yoast_meta":627,"_links":629},59445,"2025-11-04T12:48:43","2025-11-04T11:48:43",{"rendered":567},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=59445&_wpnonce=4946f5c993&status=auto-draft&type=post","2025-11-10T08:33:03","2025-11-10T07:33:03","genetic-testing-with-sequencing-com","https:\u002F\u002Fmedicalfuturist.com\u002Fgenetic-testing-with-sequencing-com",{"rendered":573},"Genetic Testing With Sequencing.com",{"rendered":575,"protected":16},"\n\u003Cp>I’ve had countless \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fgenetic-testing-whats-next\">genetic tests over the years\u003C\u002Fa>. I know my medication sensitivities, disease risks, and even my skin cancer predisposition. But when the Creator Marketing Manager at \u003Ca href=\"https:\u002F\u002Fsequencing.com\">Sequencing.com\u003C\u002Fa> — a platform for whole-genome analysis — reached out, I was curious to dive in again.\u003C\u002Fp>\n\n\n\n\u003Cp>As \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fhow-do-we-review-technologies\u002F\">always\u003C\u002Fa>, this is \u003Cstrong>not a sponsored post\u003C\u002Fstrong>. I received a free test, but I don’t accept payment for reviews. What follows is my honest, hands-on experience.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Who Are They?\u003C\u002Fh3>\n\n\n\n\u003Cp>Sequencing.com provides comprehensive insights into health, wellness, medication reactions, and genealogy by analyzing your \u003Cstrong>entire genome\u003C\u002Fstrong>. Their mission is simple but ambitious: to empower people to take control of their health and make informed decisions based on their DNA.\u003C\u002Fp>\n\n\n\n\u003Cp>Sampling is straightforward: a quick buccal swab that takes only a few minutes. The waiting time for results is about a month, which is fairly standard for full-genome sequencing.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What Kind of Results Do You Get?\u003C\u002Fh3>\n\n\n\n\u003Cp>Once the data is processed, you get access to a wide range of reports organized into categories like:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>Nutritional & Metabolic Health\u003C\u002Fli>\n\n\n\n\u003Cli>Medication & Drug Response\u003C\u002Fli>\n\n\n\n\u003Cli>Brain Health\u003C\u002Fli>\n\n\n\n\u003Cli>AI Cardiovascular Health\u003C\u002Fli>\n\n\n\n\u003Cli>Cancer Risk\u003C\u002Fli>\n\n\n\n\u003Cli>Healthcare Pro\u003C\u002Fli>\n\n\n\n\u003Cli>Wellness and Longevity\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cp>Each report lists how many \u003Cstrong>conditions, genes, and variants\u003C\u002Fstrong> were screened. They’re also categorized by \u003Cstrong>confidence level\u003C\u002Fstrong> (high, medium, or low), with clear counts for risk factors, carrier states, and medication responses.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"416\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2025\u002F11\u002FScreen-Shot-11-04-25-at-11.42-AM-768x416.png\" alt=\"\" class=\"wp-image-59447\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2025\u002F11\u002FScreen-Shot-11-04-25-at-11.42-AM-768x416.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2025\u002F11\u002FScreen-Shot-11-04-25-at-11.42-AM.png 1446w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">My Key Findings\u003C\u002Fh3>\n\n\n\n\u003Col class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Carrier of Two Rare Genetic Conditions\u003C\u002Fstrong>\u003Cbr>The first was \u003Cstrong>3-Methylglutaconic Aciduria Type I (MGCA1)\u003C\u002Fstrong>—a rare metabolic disorder caused by mutations in the \u003Cem>AUH\u003C\u002Fem> gene. It affects how the body breaks down the amino acid leucine. Since the condition is \u003Cstrong>autosomal recessive\u003C\u002Fstrong>, it only manifests if both parents carry faulty copies.\u003Cbr>I also carry a variant for \u003Cstrong>Glycogen Storage Disease XV\u003C\u002Fstrong>.\u003Cbr>We already have two children and don’t plan to have more, but if we were before family planning, I’d definitely want to know this and have my partner tested as well.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Medication Sensitivities Confirmed\u003C\u002Fstrong>\u003Cbr>The report reaffirmed previous results: I’m sensitive to \u003Cstrong>statins\u003C\u002Fstrong> and certain \u003Cstrong>antidepressants\u003C\u002Fstrong>. It’s always reassuring to see cross-validation between tests.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Cancer Risks\u003C\u002Fstrong>\u003Cbr>With medium confidence, the software suggested elevated risks for \u003Cstrong>lip and oral cavity carcinoma\u003C\u002Fstrong> and \u003Cstrong>lung cancer\u003C\u002Fstrong>.\u003Cbr>I already see my dentist twice a year and get a low-dose CT every two years: so my preventive routines are in place.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Healthcare Pro Report Highlights\u003C\u002Fstrong>\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Hypercholesterolemia:\u003C\u002Fstrong> Genetic, so not easily improved through diet, but statin sensitivity complicates treatment.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Factor V Leiden mutation:\u003C\u002Fstrong> I’ll visit a thrombosis specialist to learn preventive steps, especially before long flights.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Cardiovascular Risk:\u003C\u002Fstrong> 57% compared to a 40% population average. I don’t smoke, exercise regularly, eat well, and just had a cardiac CT scan.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Knee Osteoarthritis:\u003C\u002Fstrong> High genetic risk. I still run and play football, but I counterbalance that with therapy and recovery tools.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Atrial Fibrillation:\u003C\u002Fstrong> My smartwatch and recent cardiac exam help me monitor it closely.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Colon Cancer:\u003C\u002Fstrong> Regular colonoscopies every five years since age 35.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Melanoma:\u003C\u002Fstrong> I get screened yearly, and practically live like a vampire.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Brain Aneurysm:\u003C\u002Fstrong> Recent MRI was clear.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Noise-Induced Hearing Loss:\u003C\u002Fstrong> No issues detected.\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Asthma & Lactose Intolerance:\u003C\u002Fstrong> The latter appeared in adulthood, which I can confirm first-hand.\u003C\u002Fli>\n\u003C\u002Ful>\n\u003C\u002Fli>\n\u003C\u002Fol>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What’s New: AI Integration and Evolving Reports\u003C\u002Fh3>\n\n\n\n\u003Cp>Sequencing.com includes \u003Cstrong>generative AI\u003C\u002Fstrong> as part of its platform. You can chat with an AI assistant trained to interpret your genetic data, an interesting step toward making genomics more accessible.\u003C\u002Fp>\n\n\n\n\u003Cp>They also \u003Cstrong>update reports as new research emerges\u003C\u002Fstrong>, and you can buy additional reports in their marketplace. For example, I tried the \u003Cem>Einstein Report\u003C\u002Fem> to see if we might be distantly related. Sadly, no luck there.\u003C\u002Fp>\n\n\n\n\u003Cp>However, not all results are clear-cut. Many findings come with \u003Cstrong>low confidence levels\u003C\u002Fstrong>, which is why I strongly recommend reviewing them with a \u003Cstrong>genetic counselor\u003C\u002Fstrong> rather than making any decisions on your own. For example, it was incredibly hard to find out whether I’m heterozygous or homozygous for Factor V Leiden mutation.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">How Much Does It Cost?\u003C\u002Fh3>\n\n\n\n\u003Cp>Depending on the package, prices range from \u003Cstrong>$399 to $999\u003C\u002Fstrong>, which is competitive for full-genome sequencing services.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">My Verdict\u003C\u002Fh3>\n\n\n\n\u003Cp>The sampling and setup processes were effortless, and accessing results was simple. The \u003Cstrong>dashboard is modern and intuitive\u003C\u002Fstrong>, but the \u003Cstrong>overlap between reports\u003C\u002Fstrong> (e.g., cancer risks appearing in both Cancer and Healthcare Pro sections) can be confusing.\u003C\u002Fp>\n\n\n\n\u003Cp>Overall, \u003Cstrong>Sequencing.com delivers on its promise\u003C\u002Fstrong>: empowering individuals with deep genomic insight.\u003Cbr>But interpreting the findings requires \u003Cstrong>care, context, and professional guidance\u003C\u002Fstrong>, because having your entire genome in front of you is as humbling as it is empowering.\u003C\u002Fp>\n",{"rendered":577,"protected":16},"\u003Cp>I’ve had countless genetic tests over the years. I know my medication sensitivities, disease risks, and even my skin cancer predisposition. But when the Creator […]\u003C\u002Fp>\n",22404,{"_acf_changed":16,"footnotes":64},[441,5],[],[],[],[585,586,587,588,589,590,591,592,109],2967,3563,3821,4705,5469,1571,1683,1833,[594,53,116,117,118,119,120,461,123],"post-59445",{"id":578,"alt_text":596,"caption":64,"description":64,"media_type":149,"media_details":597,"post":620,"source_url":17},"TMF genome DNA genetic test human jump",{"width":598,"height":442,"file":599,"sizes":600,"image_meta":618},870,"2018\u002F11\u002F051_genomsequence_v2.png",{"medium":601,"large":604,"thumbnail":607,"medium_large":610,"large_old_512x288":611,"thumbnail_old_150x150":614,"medium_old_370x208":615,"medium_large_old_768x432":616,"large_old_512x288_old_512x288":617},{"file":602,"width":157,"height":158,"mime-type":338,"source_url":603},"051_genomsequence_v2-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F051_genomsequence_v2-370x208.png",{"file":605,"width":163,"height":164,"mime-type":338,"source_url":606},"051_genomsequence_v2-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F051_genomsequence_v2-768x432.png",{"file":608,"width":168,"height":168,"mime-type":338,"source_url":609},"051_genomsequence_v2-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F051_genomsequence_v2-150x150.png",{"file":605,"width":163,"height":164,"mime-type":338,"source_url":606},{"file":612,"width":173,"height":174,"mime-type":338,"source_url":613},"051_genomsequence_v2-512x288.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F051_genomsequence_v2-512x288.png",{"file":608,"width":177,"height":177,"mime-type":338,"source_url":609},{"file":602,"width":179,"height":180,"mime-type":338,"source_url":603},{"file":605,"width":182,"height":183,"mime-type":338,"source_url":606},{"file":612,"width":185,"height":186,"mime-type":338,"source_url":613},{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188,"keywords":619},[],22360,{"cta_type":64,"cta_color":64,"subtitle":64,"key_takeaways":622,"related_books":16,"related_posts_footer":16,"related_posts":16},[623,625],{"title":624},"\u003Cp>I’ve had countless genetic tests over the years. I know my medication sensitivities, disease risks, and even my skin cancer predisposition. But, I was curious to dive in again.\u003C\u002Fp>\n",{"title":626},"\u003Cp>I share my key findings and some future considerations too, alongside my verdict about the service.\u003C\u002Fp>\n",{"yoast_wpseo_title":628,"yoast_wpseo_metadesc":64,"yoast_wpseo_canonical":571},"Genetic Testing With Sequencing.com - The Medical Futurist",{"self":630,"collection":635,"about":637,"author":639,"replies":641,"version-history":644,"predecessor-version":648,"wp:featuredmedia":652,"wp:attachment":655,"wp:term":658,"curies":669},[631],{"href":632,"targetHints":633},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F59445",{"allow":634},[27],[636],{"href":220},[638],{"href":223},[640],{"embeddable":41,"href":226},[642],{"embeddable":41,"href":643},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=59445",[645],{"count":646,"href":647},3,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F59445\u002Frevisions",[649],{"id":650,"href":651},59481,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F59445\u002Frevisions\u002F59481",[653],{"embeddable":41,"href":654},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F22404",[656],{"href":657},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=59445",[659,661,663,665,667],{"taxonomy":11,"embeddable":41,"href":660},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=59445",{"taxonomy":248,"embeddable":41,"href":662},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=59445",{"taxonomy":251,"embeddable":41,"href":664},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=59445",{"taxonomy":254,"embeddable":41,"href":666},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=59445",{"taxonomy":257,"embeddable":41,"href":668},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=59445",[670],{"name":39,"href":40,"templated":41},{"id":672,"date":673,"date_gmt":674,"guid":675,"modified":677,"modified_gmt":678,"slug":679,"status":52,"type":53,"link":680,"title":681,"content":683,"excerpt":685,"author":61,"featured_media":687,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":688,"categories":689,"tags":697,"project_category":708,"contact_email_category":712,"yst_prominent_words":713,"class_list":718,"better_featured_image":740,"acf":763,"yoast_meta":776,"_links":778},14484,"2025-06-17T10:12:28","2025-06-17T08:12:28",{"rendered":676},"http:\u002F\u002Fmedicalfuturist.com\u002F?p=14484","2025-06-17T10:12:29","2025-06-17T08:12:29","the-amazing-future-of-dentistry-and-oral-health","https:\u002F\u002Fmedicalfuturist.com\u002Fthe-amazing-future-of-dentistry-and-oral-health",{"rendered":682},"9 Technologies That Will Shape The Future Of Dentistry",{"rendered":684,"protected":16},"\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">One of the most common childhood fears is going to the dentist. Who would not relate? Sitting in a huge chair illuminated by blinding light, enduring lengthy seated sessions with someone looking and poking inside your mouth using edgy and frightening devices, producing sounds like the screams of tortured souls from hell. And finally, when the misery is over, that same someone tells you not to eat your favourite sweets and instructs you to brush your teeth regularly. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">We’ve all been through this as a kid and childhood memories stick with us, just recalling this might send a shiver down your spine. No one likes to go to the dentist although everyone knows how crucial oral health is and how strongly it is connected to our overall health. But an armada of new technologies\u003C\u002Fspan> \u003Cspan style=\"font-weight: 400;\">from virtual reality through artificial intelligence (AI) to CRISPR will revolutionise dentistry and our whole attitude towards oral health in the future.\u003C\u002Fspan>\u003Cbr>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"455\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Fsitting-in-the-dentist-s-chair.jpg\" alt=\"Sitting in the dentist's chair - Future of Dentistry\" class=\"wp-image-14485\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Fsitting-in-the-dentist-s-chair.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Fsitting-in-the-dentist-s-chair-768x402.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Fsitting-in-the-dentist-s-chair-512x268.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Fsitting-in-the-dentist-s-chair-458x239.jpg 458w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Just like in the case of \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fmedical-specialties-with-the-biggest-potential-in-the-future\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">other medical specialties\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, disruptive innovations will have a huge impact on how dentistry will be practiced and how patients will take care of themselves in the future. Can you imagine that you might get your 3D-printed prosthesis in an hour instead of 4-5 sessions at the dentist? How about having a teledentist consultation? Or being able to grow new teeth at the age of 80? \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Let’s see how these can be the case in the future thanks to the following 9 technologies.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cb>1. Artificial intelligence\u003C\u002Fb>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Already, dentists \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fpii\u002FS1991790220301434#:~:text=AI%20has%20been%20used%20mainly,with%20superior%20quality%20patient%20care.\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">employ software\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> to get insights into clinical decision-making, but \u003C\u002Fspan>AI is changing the face of dentistry, just like it is in many other fields. For dentists, it’s transforming diagnosis, decision-making, and treatment planning. For patients, it promises more accurate care and better outcomes. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.frontiersin.org\u002Farticles\u002F10.3389\u002Ffdmed.2023.1085251\u002Ffull\" target=\"_blank\">This study\u003C\u002Fa> summarises how AI is adding value to various segments of the field.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Operative dentistry: finding cavities earlier\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Even with X-rays, dentists sometimes miss small cavities, especially in tricky spots like between teeth. AI can detect early-stage dental caries and vertical root fractures more accurately than traditional methods in a cost-effective way. Problems that get treated earlier, prevent the need for major work later – a huge win for all of us as patients. This is not science fiction, using neural networks can better \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.rdhmag.com\u002Fcareer-profession\u002Farticle\u002F14185563\u002Fartificial-intelligence-ai-in-dentistry\" target=\"_blank\">detect dental decay\u003C\u002Fa> (and periodontal disease) from radiographs.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Periodontics: protecting your gums\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Gum disease (periodontitis) can be hard to spot in its early stages, but it’s a major cause of tooth loss. AI helps dentists catch it early, so treatment can be simpler and more effective. It’s like adding an expert gum specialist to the team.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Orthodontics: planning the perfect smile\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Creating the ideal orthodontic treatment plan (braces and Co.) is time-consuming and takes lots of measurements and analysis. AI models help orthodontists create the best treatment plans, and predict how the result will look like. This means faster results and less guesswork.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>AI in oral and maxillofacial pathology: early detection, targeted treatments\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Oral cancers and other serious issues can lurk undetected with biopsies being the only way to diagnose them. AI is getting good at analysing scans and microscope slides. It can identify suspicious areas that need closer examination and can help distinguish between tumor types. This can lead to earlier cancer detection and more targeted treatment. Researchers in 2019 \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fs41598-019-49710-z\" target=\"_blank\">developed a machine learning method\u003C\u002Fa> to accurately quantify immune cells in the vicinity of oral cancer cells. This gives better insights into the spread of and resistance to cancer; thereby \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalxpress.com\u002Fnews\u002F2019-09-ai-chances-surviving-oral-cancer.html\" target=\"_blank\">helping in determining\u003C\u002Fa> the chances of survival.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Prosthodontics: designing better restorations\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Crowns, dentures, and other restorations have to be custom-made for a perfect fit – a time-consuming process. Various AI models can assist this process by generating perfect dental crowns and dentures through CAD integration and improving shade matching. \u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image is-style-default\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"1080\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F10\u002F214_tmf-01-1.png\" alt=\"\" class=\"wp-image-30807\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F10\u002F214_tmf-01-1.png 1920w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F10\u002F214_tmf-01-1-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F10\u002F214_tmf-01-1-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F10\u002F214_tmf-01-1-1536x864.png 1536w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \u002F>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">To think even more ahead: \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Frise-in-population-genomics-local-government-in-india-will-use-blockchain-to-secure-genetic-data\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">genomic data\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> can offer a \u003C\u002Fspan>deeper understanding \u003Cspan style=\"font-weight: 400;\">for personalised care. With AI tools having access to such information, they can instantly offer the best treatment options and probabilities of success.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cstrong>2. Smart toothbrush\u003C\u002Fstrong>\u003C\u002Fh3>\n\n\n\n\u003Cp>While AI helps dental professionals provide better treatments, smart toothbrushes enable all of us to take better care of our teeth. Our home will be filled with connected, smart devices in the future, so why would our bathroom be an exception?\u003Cspan style=\"font-weight: 400;\"> At first, it might feel a bit strange to let a sensor into one of your most intimate activities, tooth brushing, but it makes a lot easier to maintain oral hygiene and prevent plaque or cavities. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">The \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.kolibree.com\u002Fen\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Kolibree smart electric toothbrush\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> makes sure you are brushing your teeth the right way through its app and offers kids fun games to keep up the good habit of regularly cleaning their teeth. Philips’ \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.usa.philips.com\u002Fc-m-pe\u002Felectric-toothbrushes#triggername=color_white\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Sonicare smart toothbrush\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> comes packed with sensors in its handle. These provide real-time feedback via a companion app warning you if you are applying too much pressure, where you are brushing and even coach the user as to how to brush properly. And there are so many such devices \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.amazon.com\u002Fs?k=smart+toothbrush&crid=1MFD8ISN5WMO0&sprefix=smart+tooth%2Caps%2C180&ref=nb_sb_ss_ts-doa-p_1_11\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">on the market\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"439\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fsmart-toothbrush-768x439.jpg\" alt=\"smart toothbrush\" class=\"wp-image-56057\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fsmart-toothbrush-768x439.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fsmart-toothbrush-1536x878.jpg 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fsmart-toothbrush.jpg 1792w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">While having a personal coach to optimise your daily oral hygiene might sound enticing, not everyone is enthusiastic about the technology. Firstly, dental experts emphasise \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nytimes.com\u002Fwirecutter\u002Fblog\u002Fsmart-toothbrushes-dont-recommend\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">the need for proper brushing techniques\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, which \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nytimes.com\u002Fwirecutter\u002Freviews\u002Fbest-electric-toothbrush\u002F#what-about-smart-toothbrushes\" target=\"_blank\">these devices won’t improve upon\u003C\u002Fa>. Rather, it’s a dental professional who can demonstrate the proper techniques at your next appointment. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Additionally, by buying smart toothbrushes from companies like\u003C\u002Fspan> \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.pg.com\u002Fprivacy\u002Fenglish\u002Fprivacy_statement.shtml\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Procter & Gamble\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> and \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.usa.philips.com\u002Fa-w\u002Fmobile-privacy-notice\u002Fsonicare-connected-app-gdpr.html\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Philips Oral Healthcare\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> you agree to their privacy policies that enable them to share your data with third parties. Now that \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fyour-privacy-in-the-digital-health-era-the-medical-futurists-guide\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">health data is the new oil\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, companies will want to profit off of these in as many ways as possible. So you might want to adopt a smart toothbrush from a company that gives you more control over your data or one that doesn’t share it with third parties at all.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cstrong>3. Augmented Reality\u003C\u002Fstrong>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">You might be familiar with \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Faugmented-reality-in-healthcare-will-be-revolutionary\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Augmented Reality\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> (AR) through social media apps; it’s the same technology that Snapchat uses to \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=Pc2aJxnmzh0&ab_channel=Vox\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">superimpose filters\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> on your face during your guilt trip selfie with a dog face filter. But AR also found a home in dentistry for both educational and clinical purposes.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Image Navigation’s \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fimage-navigation.com\u002Fhome-page\u002Fdentsim\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">DentSim Simulator\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> pairs AR with a mannequin on which students can perform procedures while receiving immediate feedback as their movements are tracked. This helps them identify faster where they should improve and develop their skills in the process. It’s already in by 8,500 students in dental schools around the world.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image is-style-default\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"1080\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Faugmented-reality-in-dentistry-with-logo.png\" alt=\"\" class=\"wp-image-30911\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Faugmented-reality-in-dentistry-with-logo.png 1920w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Faugmented-reality-in-dentistry-with-logo-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Faugmented-reality-in-dentistry-with-logo-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Faugmented-reality-in-dentistry-with-logo-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002Faugmented-reality-in-dentistry-with-logo-2048x1152.png 2048w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \u002F>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Cp class=\"has-text-align-left\">\u003Cspan style=\"font-weight: 400;\">In dental practice, the technology is more prevalent in reconstructive and aesthetic procedures in order to help patients know what they will look like after the treatment. \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fsmartteksas.com\u002Faugmented-reality-smile-application\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">SmartTek\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> developed an AR app that uses a phone or tablet’s camera to overlay virtual depictions of the improved set of teeth prior to the procedure. This allows patients and dentists to configure features of their teeth such as height and spacing to their liking before they even enter the surgery room.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cstrong>4. Virtual Reality in dentistry\u003C\u002Fstrong>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Not to be confused with AR, Virtual Reality (VR) completely closes off the outside world with a dedicated headset and immerses the user in a virtual environment. By slipping such a headset on their head, students and aspiring dental surgeons \u003Ca href=\"https:\u002F\u002Fwww.voanews.com\u002Fa\u002Fepisode_absence-person-classes-dentistry-courses-use-virtual-reality-4725316\u002F6117310.html\" target=\"_blank\" rel=\"noreferrer noopener\">can be transported to the OR from their couch\u003C\u002Fa>; while patients can visualise a calming landscape while seated at the dreaded dentist’s chair to improve their experience.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Today, only a few students can peek over the shoulder of the surgeon during an operation and it is challenging to learn the tricks of the trade like that. With a virtual reality camera, surgeons can stream operations globally and allow medical students to actually be there in the OR using their VR goggles. Dentistry even outpaced other fields of medicine in adopting this method. Back in 2015, Nobel Biocare \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fvrscout.com\u002Fnews\u002Fdental-surgery-virtual-reality\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">held the first dental surgery\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> filmed through VR and allowed observers to virtually assist the whole procedure from the surgeon’s perspective. In comparison, the first VR-recorded surgery was performed at \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.theguardian.com\u002Ftechnology\u002F2016\u002Fapr\u002F14\u002Fcutting-edge-theatre-worlds-first-virtual-reality-operation-goes-live\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">the Royal London Hospital\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> in 2016. The technology can further be used to help dentists \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002F5-ways-medical-vr-is-changing-healthcare\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">build on their empathy skills\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> through simulations putting them in the shoes of their patients or in challenging situations. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image is-style-default\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1440\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F09\u002F105_Do-scalable-simulations-prepare-for-medical-realities-scaled.gif\" alt=\"medical virtual simulation\" class=\"wp-image-24685\"\u002F>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">On the patient side, VR might be the solution to our dentist’s office anxiety. \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fjournals.plos.org\u002Fplosone\u002Farticle?id=10.1371%2Fjournal.pone.0091276\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">An experiment showed\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> that VR can be used as an effective distraction tool in dentistry. Patients wore goggles which displayed calming natural scenes, and remembered the treatments more positively afterwards. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cstrong>5. Teledentistry\u003C\u002Fstrong>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">If you are reluctant to go to the dentist, imagine how hard it is for children, patients with special needs or the elderly in nursing homes. Another issue is distance: people living in rural areas rarely get access to a dentist and hardly ever have the possibility of choice. This can change significantly with the spread of teledentistry. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Teledentistry services offered by companies like \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.theteledentists.com\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">The Teledenists\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> and \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.mouthwatch.com\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">MouthWatch\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> provide easier access to oral and dental care; are significantly cheaper for patients; shift towards cheaper prevention practices; and allow patients to consult with otherwise unavailable medical professionals. For instance, MouthWatch’s TeleDent service offers an all-in-one teledentistry platform allowing patients to capture images, send relevant information to a dentist remotely, and do a live consult. The dentist might start a video chat with the patient and the caregiver so that the medical professional can actually see and talk to the patient, build rapport, help connect them and bring them into the office (if necessary).\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image is-style-default\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"1080\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F0625_berlin_teledentistry.png\" alt=\"\" class=\"wp-image-30913\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F0625_berlin_teledentistry.png 1920w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F0625_berlin_teledentistry-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F0625_berlin_teledentistry-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F0625_berlin_teledentistry-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F0625_berlin_teledentistry-2048x1152.png 2048w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \u002F>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Cp class=\"has-text-align-left\">\u003Cspan style=\"font-weight: 400;\">The American Dental Association issued \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.ada.org\u002Fabout\u002Fgovernance\u002Fcurrent-policies\u002Fada-policy-on-teledentistry\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">a policy on teledentistry\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> that offers guidance on the modalities that such services can follow. This sets the pace in making teledentistry a general practice.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cstrong>6. Computer-assisted design and 3D-printing \u003C\u002Fstrong>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">3D printing does not need any introduction considering the buzz it generated in healthcare a while ago with \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" style=\"\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002F3d-printing-in-medicine-and-healthcare\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">the technology’s potential to print\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> medicines, prosthetics and even organ replicas. Its importance was \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" style=\"\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fdigital-health-tech-here-to-stay-after-covid-19\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">also highlighted during the COVID-19 crisis\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> to bypass supply chains to meet hospitals’ demands. As the technology is set to become an integral part of healthcare practice, it will also become incorporated into dental labs.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Computer-assisted design (CAD) and computer-assisted manufacture (CAM), including 3D-printing, are \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">already revolutionising the sector; \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">they are turning them into low-cost, more effective digital labs. Traditionally, when a patient needs a crown, a dentist must make a mould of the tooth and fashion a temporary crown, then wait for the dental laboratory to make a permanent one.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image is-style-default\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"1080\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo.png\" alt=\"\" class=\"wp-image-30915\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo.png 1920w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-2048x1152.png 2048w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \u002F>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">With \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.webmd.com\u002Foral-health\u002Fadvances-in-dental-care-whats-new-at-the-dentist#2\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">CAD\u002FCAM technology\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, the tooth is drilled to prepare it for the crown and a picture is taken with a computer. This image is then relayed to a machine that manufactures the crown right in the office. With a 3D printer doing the hard work, dental labs eliminate the bottleneck of manual modelling and let the business grow. \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.stratasys.com\u002Findustries\u002Fdental\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Stratasys\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fhealth.desktopmetal.com\u002Fdental-3d-printing\u002F\" target=\"_blank\">Desktop Health,\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> or \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fformlabs.com\u002Fblog\u002F3d-printed-teeth\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">FormLabs\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> offer such high-tech solutions for dental labs.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">3D printers \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fdental.formlabs.com\u002Feu\u002Fblog\u002Fdigital-dentistry-dental-3d-printing\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">are also able to produce\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> orthodontic models, surgical guides, aligners, retainers and more dental equipment faster and more precisely; tasks that would take longer with traditional methods. This helps improve workflows, reducing error and the amount of labor needed, which ultimately endows the technology with time and cost-efficiency.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cstrong>7. Intra-oral camera\u003C\u002Fstrong>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">One of the greatest inconveniences\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\"> while being seated in\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\"> the dentists’ chair is \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">that sometimes, no matter how wide you open your mouth, the dentist still\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\"> cannot see what they would like to see, even by using the \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">trusty \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">dental mirror. \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">Such situations are not only uncomfortable \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">for both the patient and the doctor\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">, but also painful. However, the advent of\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\"> intra-oral cameras \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">can remedy\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\"> this exact problem.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.mouthwatch.com\u002Fintraoral-cameras\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">MouthWatch\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.duerrdental.com\u002Fen\u002Fproducts\u002Fimaging\u002Fvistacam-intraoral-camera-systems\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Dürrdental\u003C\u002Fspan>\u003C\u002Fa> \u003Cspan style=\"font-weight: 400;\">and \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.carestreamdental.com\u002Fus\u002Fen\u002Fintraoralcamera\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Carestream Dental\u003C\u002Fspan>\u003C\u002Fa> \u003Cspan style=\"font-weight: 400;\">are some of the many companies to have launched intra-oral cameras on the market. The cameras’ unique liquid lens technology works like the human eye to ensure effortless image capture to deliver clear, detailed images patients can really understand.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cb>8. Regenerative dentistry\u003C\u002Fb>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">We’ve come to expect to have our teeth fall off with age or with damage and have them replaced by prostheses. However, \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fsj.bdj.2014.961\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">regenerative dentistry\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> challenges this preconceived idea with developments that can lead to self-healing teeth and biological therapy for damaged teeth. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>A Japanese startup, Toregem Biopharma will launch clinical trials in September of what is believed to be the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fasia.nikkei.com\u002FBusiness\u002FPharmaceuticals\u002FWorld-s-first-tooth-regenerating-drug-to-enter-testing-in-Japan\" target=\"_blank\">first-ever treatment that can regrow teeth\u003C\u002Fa>. The drug is designed to help patients missing some or all of their teeth from birth – a condition named congenital anodontia. However, the Kyoto University-affiliated startup hopes to eventually offer a solution to patients who lost their teeth later in life as well. \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Previously, researchers from the University of Nottingham and Harvard University\u003C\u002Fspan> \u003Ca href=\"http:\u002F\u002Feurope.newsweek.com\u002Fdental-fillings-heal-teeth-stem-cells-harvard-cavities-477415?rm=eu\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">developed dental fillings\u003C\u002Fspan>\u003C\u002Fa> \u003Cspan style=\"font-weight: 400;\">that allow teeth to heal themselves. These fillings stimulate stem cells to promote the growth of dentin, or the main constituent of our teeth. This effectively enables patients to regrow teeth damaged through dental disease and potentially eliminate the need for root canals!\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Discoveries from researchers at Karolinska Institutet \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fscitechdaily.com\u002Fregenerative-dentistry-breakthrough-biological-therapy-for-damaged-teeth\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">can accelerate development\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> in the field of regenerative medicine. They were able to map the differentiation pathways of the cells that make up human teeth. They also discovered new cell types and cell layers in teeth that can impact tooth sensitivity.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Isn’t it exciting to think that you might not need to have false teeth to replace your own when you are old, but you might grow new ones? The tooth fairy will be very excited for sure!\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cstrong>9. CRISPR\u003C\u002Fstrong>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">CRISPR is a ground-breaking genome editing method offered by Mother Nature herself, but researchers have discovered its immense potential only recently. As explored in our dedicated articles, it might \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fcrispr\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">become the ultimate weapon against cancer\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> or, more controversially, \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhat-could-crisprcas9-do-tomorrow\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">help design babies in the future\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">. And the field of dentistry will also benefit from the technology as well.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image size-full wp-image-22535 is-style-default\">\n\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"491\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F12\u002FCRISPR_Gene-Editing.jpg\" alt=\"digital health technologies\" class=\"wp-image-22535\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F12\u002FCRISPR_Gene-Editing.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F12\u002FCRISPR_Gene-Editing-370x208.jpg 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F12\u002FCRISPR_Gene-Editing-768x433.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F12\u002FCRISPR_Gene-Editing-512x289.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.verdict.co.uk\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">So what could CRISPR achieve in dentistry? Well quite a lot, in fact. Chinese researchers \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.todaysrdh.com\u002Fwhat-is-crispr-and-how-could-it-change-dentistry\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">are conducting studies\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> with the technology to isolate and switch off oral cancer-associated genes. Other researchers are \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fpubmed.ncbi.nlm.nih.gov\u002F30329221\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">using CRISPR\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> to alter the functioning of bacteria responsible for plaque formation. Their endeavour could even lead to the reduction or outright prevention of dental caries and periodontal disease. But please don’t give up on brushing your teeth just yet!\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">\u003Cb>The bright future of dental medicine\u003C\u002Fb>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">It is amazing how more and more disruptive innovations will be at our disposal – either for improving oral health (and getting rid of the dentist-related fear and anxiety) as a patient or upgrading your practice as a professional. Our task at The Medical Futurist is to follow the latest innovations and keep pace with the growing possibilities in healthcare.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Be sure to pick up a copy of \u003Ca href=\"https:\u002F\u002Fleanpub.com\u002Ffuture-of-medical-specialties\" target=\"_blank\" rel=\"noreferrer noopener\">our e-book\u003C\u002Fa> to learn more about the technological future of medical specialties!\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"1920\" height=\"1080\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2019\u002F05\u002F0415_tmfs_mockup.png\" alt=\"future of medical specialties\" class=\"wp-image-23819\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F05\u002F0415_tmfs_mockup.png 1920w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F05\u002F0415_tmfs_mockup-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F05\u002F0415_tmfs_mockup-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F05\u002F0415_tmfs_mockup-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F05\u002F0415_tmfs_mockup-2048x1152.png 2048w\" sizes=\"auto, (max-width: 1920px) 100vw, 1920px\" \u002F>\u003C\u002Ffigure>\n",{"rendered":686,"protected":16},"\u003Cp>One of the most common human fears is going to the dentist, although we all know  how crucial oral health is and how strongly it is connected to our overall health. Let’s see what new technologies can do to  revolutionise dentistry – and our attitudes.\u003C\u002Fp>\n",30915,{"_acf_changed":16,"footnotes":64},[690,691,280,692,441,281,5,693,694,695,696],498,504,491,496,516,494,514,[698,699,700,701,702,703,82,704,88,705,706,446,707],130,598,134,671,145,206,275,445,517,597,[709,710,711,452,453],947,948,949,[],[714,592,715,101,716,717],1725,2261,1715,1719,[719,53,116,117,118,119,120,720,721,314,722,461,315,123,723,724,725,726,727,728,729,730,731,732,135,733,141,734,735,465,736,737,738,739,470,471],"post-14484","category-3d-printing","category-artificial-intelligence","category-empowered-patients","category-health-sensors-trackers","category-medical-education","category-telemedicine","category-virtual-reality","tag-3d-printing-2","tag-oral-health","tag-ai","tag-machine-learning","tag-augmented-reality-2","tag-digital","tag-healthcare","tag-virtual-reality","tag-gc1","tag-dentistry","project_category-company","project_category-developers","project_category-educators",{"id":687,"alt_text":64,"caption":64,"description":741,"media_type":149,"media_details":742,"post":672,"source_url":762},"An armada of new technologies from virtual reality through A.I. to CRISPR will revolutionise dentistry in the future. ",{"width":332,"height":333,"file":743,"sizes":744,"image_meta":761},"2016\u002F11\u002F3d-printing-dentistry-with-logo.png",{"medium":745,"large":748,"thumbnail":751,"medium_large":754,"1536x1536":755,"2048x2048":758},{"file":746,"width":179,"height":180,"mime-type":338,"source_url":747},"3d-printing-dentistry-with-logo-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-370x208.png",{"file":749,"width":182,"height":183,"mime-type":338,"source_url":750},"3d-printing-dentistry-with-logo-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-768x432.png",{"file":752,"width":177,"height":177,"mime-type":338,"source_url":753},"3d-printing-dentistry-with-logo-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-150x150.png",{"file":749,"width":182,"height":183,"mime-type":338,"source_url":750},{"file":756,"width":349,"height":350,"mime-type":338,"source_url":757},"3d-printing-dentistry-with-logo-1536x864.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-1536x864.png",{"file":759,"width":354,"height":355,"mime-type":338,"source_url":760},"3d-printing-dentistry-with-logo-2048x1152.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo-2048x1152.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F11\u002F3d-printing-dentistry-with-logo.png",{"related_posts":16,"related_posts_footer":764,"cta_type":364,"cta_color":64,"subtitle":64,"related_books":768,"key_takeaways":771},[765,766,767],13061,13172,13916,[769,770,509],30419,24762,[772,774],{"title":773},"\u003Cp>Disruptive innovations will have a huge impact on how dentistry will be practiced and how patients will take care of their oral health in the future.\u003C\u002Fp>\n",{"title":775},"\u003Cp>These technologies will result in better and more personalized care, faster solutions, often at lower costs than today.\u003C\u002Fp>\n",{"yoast_wpseo_title":682,"yoast_wpseo_metadesc":777,"yoast_wpseo_canonical":680},"Let's look at the top digital technologies from virtual reality through A.I. to CRISPR that will revolutionise dentistry in the future.",{"self":779,"collection":784,"about":786,"author":788,"replies":790,"version-history":793,"predecessor-version":797,"wp:featuredmedia":801,"wp:attachment":804,"wp:term":807,"curies":818},[780],{"href":781,"targetHints":782},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F14484",{"allow":783},[27],[785],{"href":220},[787],{"href":223},[789],{"embeddable":41,"href":226},[791],{"embeddable":41,"href":792},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=14484",[794],{"count":795,"href":796},66,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F14484\u002Frevisions",[798],{"id":799,"href":800},58855,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F14484\u002Frevisions\u002F58855",[802],{"embeddable":41,"href":803},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F30915",[805],{"href":806},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=14484",[808,810,812,814,816],{"taxonomy":11,"embeddable":41,"href":809},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=14484",{"taxonomy":248,"embeddable":41,"href":811},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=14484",{"taxonomy":251,"embeddable":41,"href":813},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=14484",{"taxonomy":254,"embeddable":41,"href":815},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=14484",{"taxonomy":257,"embeddable":41,"href":817},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=14484",[819],{"name":39,"href":40,"templated":41},{"id":821,"date":822,"date_gmt":823,"guid":824,"modified":826,"modified_gmt":827,"slug":828,"status":52,"type":53,"link":829,"title":830,"content":832,"excerpt":834,"author":61,"featured_media":836,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":837,"categories":838,"tags":845,"project_category":869,"contact_email_category":872,"yst_prominent_words":873,"class_list":877,"better_featured_image":910,"acf":931,"yoast_meta":945,"_links":948},12808,"2025-04-22T09:06:47","2025-04-22T07:06:47",{"rendered":825},"http:\u002F\u002Fthemedicalfuturist.melkweg.hu\u002F?p=12808","2025-04-22T13:09:28","2025-04-22T11:09:28","technologies-that-will-shape-the-future-of-cancer-care","https:\u002F\u002Fmedicalfuturist.com\u002Ftechnologies-that-will-shape-the-future-of-cancer-care",{"rendered":831},"13 Technologies That Will Shape The Future Of Cancer Care",{"rendered":833,"protected":16},"\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Cancer is \u003C\u002Fspan>a \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.who.int\u002Fnews-room\u002Ffact-sheets\u002Fdetail\u002Fcancer\" target=\"_blank\">leading cause of death worldwide\u003C\u002Fa>, accounting for nearly 10 million deaths annually, or nearly one in six deaths\u003Cspan style=\"font-weight: 400;\">. It poses a physical, emotional and financial burden on individuals, families, societies and governments.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Cancer research is one of the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-digital-health-future-of-oncology\u002F\" target=\"_blank\">most significant areas of research\u003C\u002Fa> in healthcare worldwide. The inventions that led to the rapid COVID-19 vaccine developments originally were aimed at curing cancer – \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fmrna-vaccines-from-tackling-pandemic-to-treating-cancer\" target=\"_blank\">the mRNA technology\u003C\u002Fa>, for example. Today, it has become a forward-looking concept for cancer immunotherapy, and researchers \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmolecular-cancer.biomedcentral.com\u002Farticles\u002F10.1186\u002Fs12943-021-01335-5\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">expect the field to grow\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> convincingly in the future. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">The three essential levels in cancer care are \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cspan style=\"font-weight: 400;\">prevention and diagnosis, \u003C\u002Fspan>\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cspan style=\"font-weight: 400;\">treatment,\u003C\u002Fspan>\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cspan style=\"font-weight: 400;\">and monitoring of the disease\u003C\u002Fspan>\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cp>can help beat cancer for good. The technologies we list below are separated according to these phases.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cb>Prevention and diagnosis \u003C\u002Fb>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Cancer diagnosis must be early and accurate. Many cancer types cannot yet be detected early enough, while others are caught in time but treated too severely. This notion requires excellent healthcare facilities, new diagnosis technologies, and the proactivity of patients. We’ll see the following fields to earn additional momentum in the coming years.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">1. Liquid biopsy\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.cancer.gov\u002Fpublications\u002Fdictionaries\u002Fcancer-terms\u002Fdef\u002Fliquid-biopsy\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Liquid biopsy\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> is the analysis of tumours using biomarkers circulating in fluids such as the blood. It can be used for the early detection of cancer. During cancer treatments, re-biopsies are needed to adjust the treatment plan. It means taking a new sample from the ever-changing tumour to define the next step of the therapy. With the current invasive biopsy techniques, this is a considerable challenge for patients and medical professionals alike. Fluid biopsy extracts cancer cells from a simple blood sample. The use of \u003Ca href=\"https:\u002F\u002Fwww.nature.com\u002Fsearch?q=liquid%20biopsy&date_range=last_year&order=relevance\" target=\"_blank\" rel=\"noreferrer noopener\">biomarkers in the blood is transforming\u003C\u002Fa> cancer diagnosis \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fd41586-020-00844-5\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">already\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, and I firmly believe the method should be the primary process for all biopsies where possible.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">2. Real-time cancer diagnostics\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">There are multiple exciting technologies for the diagnosis of tumours during surgery. A large-scale \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fpubmed.ncbi.nlm.nih.gov\u002F31342360\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">study in 2019 found\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> that over 20% of women who had breast cancer had to undergo a second operation because malignant cells had been left undetected the first time. A new tool that \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.massdevice.com\u002Fthis-imaging-device-could-be-a-breakthrough-for-breast-cancer-treatment\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">got the FDA breakthrough\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> device designation in October 2020 aims to solve this issue. OncoRes Medical’s imaging device provides essential intraoperative information available to surgeons during a lumpectomy. The handheld device uses AI to assist with identifying tumour and healthy tissue, thereby \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fddebaa16-b003-4ac2-b05d-06b4e7c28ad4.filesusr.com\u002Fugd\u002F611b88_f20c26e047c3496e8096ef84f0933557.pdf\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">substantially improving\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> outcomes in breast-conserving surgery and reducing repeat operations for women with breast cancer.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">3. Understanding genetic and lifestyle causes of diseases\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">By getting some explicit knowledge about what genetic and environmental factors lead to the different types of cancers, including the given patient’s genetic makeup; it would be possible to catch cancer in its infancy. This requires process innovation in healthcare and more precise and specific cancer biomarkers supported by \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fsearch\u002F?term=DNA%20test\" target=\"_blank\">better screening technologies\u003C\u002Fa>. For example, when I took the \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fatlas-biomed-genetic-test-review\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Atlas Biomed genetic test\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, I learnt a lot about my own body and how it works, and by knowing the risk factors, I was able to design a preventive plan with my primary care physicians and my genetic counsellor. On the downside, Atlas doesn’t examine the gene variants for complex cancer risks. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F02\u002Ftmf_article_243-01-768x432.png\" alt=\"\" class=\"wp-image-32629\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F02\u002Ftmf_article_243-01-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F02\u002Ftmf_article_243-01-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F02\u002Ftmf_article_243-01-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F02\u002Ftmf_article_243-01.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">However, another company, \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fi-got-my-whole-genome-sequenced-heres-what-i-learned\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Dante Labs \u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">does so. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=HOEMj3J_BrU&t=1s\" target=\"_blank\">Their \u003C\u002Fa>DNA package contains a hereditary cancer report with risks, e.g. for colorectal or prostate cancer, but I must warn you to take these results with caution: risks and actual diseases are two different things.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cb>Treatment\u003C\u002Fb>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Cancer treatment varies from surgery and various therapies to destroy any malignant cells in the body, targeted therapies and stem cell transplants. Biomarkers can help determine what kind of therapy would work best. Precision oncology helps find the available targeted therapies. The price of new drugs is going up steeply, and personalised drugs cost even more – but they bear the promise of being more effective than generic medications. As medical and technological innovations expand cancer treatment, the possibility for super-focused drugs is \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC6352312\u002F\">\u003Cspan style=\"font-weight: 400;\">getting nearer\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> in oncology treatments.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">4. Next-generation targeted therapies\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">There are drugs that can block cancer growth or spread by interfering with specific molecules involved in the development, progression, and spread of cancer. Such \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.cancer.gov\u002Fabout-cancer\u002Ftreatment\u002Ftypes\u002Ftargeted-therapies\u002Ftargeted-therapies-fact-sheet\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">targeted therapies\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> are designed only to stop cancerous cells, using information about a person’s genes and proteins. Such precision drugs can \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC6352312\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">contribute to the prevention\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, diagnosis and treatment of the disease, resulting in unbounded patient benefits. Next-generation targeted therapies have already gained momentum in the past couple of years. I expect the field to take off rapidly as the costs of the technology will inevitably go down as the technology will be more available, therefore more affordable.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">5. Molecular cancer diagnostics\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Matching the right targeted therapy to the right patient based on the individual molecular genetic alterations in each cancer patient’s tumour is a promising and attractive precision oncology approach. \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.oncompassmedicine.com\u002F\">\u003Cspan style=\"font-weight: 400;\">Oncompass Medicine\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> uses AI-based algorithms to match genetic mutations found in patients’ tumour samples with effective targeted cancer therapies. This way, patients can receive precisely targeted treatments specific to the kind of cancerous tissue they have. Their RealTime Oncology Treatment Calculator can significantly improve the selection of the right targeted therapy for each cancer patient based on the individual molecular genetic profile of their cancer.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">6. AI-based therapy design\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Even if we can extract tumour cells from blood and sequence their DNA as fast as possible, deciding on the treatment is still a struggle. No oncologist can see through the millions of studies and thousands of clinical trials by keeping all of the patient’s parameters and mutations in mind. However, artificial intelligence algorithms can. In the U.K., Addenbrooke’s Hospital in Cambridge uses \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.healthcareitnews.com\u002Fnews\u002Femea\u002Fuk-hospital-first-use-ai-cancer-treatment-tool\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Project InnerEye\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, an AI deep-learning tool supporting the treatment of cancer patients. The AI analyses hospital data to identify tumours on patient scans. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-768x432.png\" alt=\"AI medical coding doctor, hospital, clinic, man, laptop, computer\" class=\"wp-image-51069\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-2048x1152.png 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">And it’s amazingly reliable, cutting CT processing times and treatment planning by up to 90%. Dutch researchers developed an evolutionary algorithm with intelligent search behaviour to generate better solutions at an ever-increasing speed. The AI created \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.cwi.nl\u002Fnews\u002Fblogs\u002Fai-calculates-best-treatment-plan\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">“\u003Cem>better plans and more insight\u003C\u002Fem>\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">\u003Cem> than the doctors thought possible\u003C\u002Fem>.”\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">7. In silico trials\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">In principle, clinical trials take years and cost more than 2 billion dollars for every approved treatment. The number of failed drug candidates is enormous, so spending years and millions on a clinical trial is no guarantee to lead to an approved treatment. However, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-future-of-clinical-trials-artificial-patients-synthetic-data-and-real-time-analysis\" target=\"_blank\">the world of clinical trials is changing\u003C\u002Fa>. Trials should unquestionably use more data and AI models. \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fpharmaphorum.com\u002Fdigital\u002Fnow-what-the-future-of-clinical-trials-after-the-pandemic\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">It is inevitable\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> to build the right skill sets to implement new technologies. Novel approaches like in silico trials with advanced biological networks, organs-on-a-chip or even network medicine will then help choose the right drug candidates within seconds.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">8. DNA cages\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Most cancer treatments today destroy not only cancerous cells but also healthy ones. The ultimate goal is to deliver drugs only to cells that need to be treated. Using DNA cages holding medications might be the answer. Cancer cells can trigger the \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.frontiersin.org\u002Farticles\u002F10.3389\u002Ffphar.2019.01585\u002Ffull\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">DNA cage\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> to open, and thus the drug could only impact those cells, but not the healthy ones. The next level of this targeted therapy is \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.imperial.ac.uk\u002Fnews\u002F218893\u002Fcancer-drugs-could-delivered-molecular-cages\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">investigated\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> at The Imperial College London, where researchers used light as a trigger to open the cage and release the drug inside.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">9. Precision surgery\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Surgeons using surgical robots such as DaVinci are capable of performing operations with previously unachievable precision. By making the robot an extension of the surgeon’s mind and skills, operating tumours in early stages or tumours close to sensitive organs might become more feasible than ever. \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-technological-future-of-surgery\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Surgical robots today\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> have 3D cameras that can \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.nytimes.com\u002F2021\u002F04\u002F30\u002Ftechnology\u002Frobot-surgery-surgeon.html\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">record operations\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> and stream at the same time. The robot’s added value is to \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.wsj.com\u002Farticles\u002Fautonomous-robots-are-coming-to-the-operating-room-11599786000?mod=article_inline\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">assist the surgeon\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> in suturing, dissecting and retracting tissue, leading to more precision in surgery than ever.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002Ftmf_article_342-01_digital-health-hospital-768x432.png\" alt=\"hospital, digital health, device, doctor TMF, cancer care\" class=\"wp-image-48231\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002Ftmf_article_342-01_digital-health-hospital-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002Ftmf_article_342-01_digital-health-hospital-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002Ftmf_article_342-01_digital-health-hospital-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002Ftmf_article_342-01_digital-health-hospital.png 1800w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cb>Monitoring and providing care\u003C\u002Fb>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">A cancer diagnosis is a traumatic event for everyone. Although patients meet their caregivers in person many times, they are often left to cope with chronic pain or powerful side effects for the rest of the treatment and recovery process. New technologies could improve their experience – as well as the experience of their loved ones around them.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">10. Embedded, implanted and digestible sensors\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">In many cases, measuring health parameters at home would be a huge addition to cancer care. Measuring body temperature, for example, is key in monitoring the effects of chemotherapy. What if a sensor on the patient’s skin could constantly measure body temperature and notify the patient when the fever goes up? Digestible pillcams could be used to perform non-invasive routine checkups on the digestive system at home. Implanted sensors or digital tattoos could monitor every important vital sign, triggering an alarm to both the patient and the caregiver, so interventions can be planned as quickly as possible.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">While there’s a large set of wearables \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC7688381\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">oncology patients could use\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> for at-home monitoring of vital signs or physical activities, these devices aren’t used much for this purpose. Both studies on the issue and medical education are missing. However, embedded or implanted sensors (like in a \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.contactlensjournal.com\u002Farticle\u002FS1367-0484(21)00021-7\u002Ffulltext\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">contact lens\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, where the tear film is suited to detect cancer biomarkers) have a huge potential in the future.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">11. Measuring lab markers at home\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">The pandemic has pushed healthcare to use\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-rise-of-at-home-lab-tests\" target=\"_blank\"> at-home lab tests\u003C\u002Fa> more \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fdiy-blood-draw-could-patients-collect-blood-at-home\" target=\"_blank\">widely\u003C\u002Fa>. During chemotherapy, blood markers, especially white blood cell count, must be checked routinely to make sure the patient’s immune system is still intact. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002F5.-controversial-Tasso-768x432.png\" alt=\"\" class=\"wp-image-48431\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002F5.-controversial-Tasso-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002F5.-controversial-Tasso-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002F5.-controversial-Tasso.png 1066w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Cancer patients with easily compromised immune systems face more challenges in this regard when visiting busy hospitals. \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fthepathologist.com\u002Fsubspecialties\u002Fhome-based-tests-for-cancer-patients\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Point-of-care testing\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> (POCT) can provide a viable option. At-home testing and diagnostic options will \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedcitynews.com\u002F2020\u002F07\u002Fthe-role-of-home-based-blood-diagnostics-in-future-cancer-care\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">keep patients safe\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> and their immune systems intact.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">12. Patient networks\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Networking sites such as \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.smartpatients.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">SmartPatients\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> (originally a cancer patient empowering site) were designed to help patients find and support each other. These channels offer a lively community where patients, families and caregivers learn from each other about treatments, clinical trials or the latest science. The feeling of community and seeing others cope with the same hardships can boost not just the mental but also the physical well-being of cancer patients.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">13. Pain management\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Cancer and its treatments can induce extreme, chronic pain. In the past, cancer patients were relegated to continuous, increasing doses of painkillers and opioids. Companies are now developing devices that help ease symptoms and side effects. A good example is \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fclinicaltrials.gov\u002Fct2\u002Fshow\u002FNCT02809846\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">Quell\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, a wearable technology with intensive nerve stimulation clinically proven to help manage chronic pain. It’s FDA-approved and clinically proven to relieve chronic pain. Another technology, \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.sciencedirect.com\u002Fscience\u002Farticle\u002Fabs\u002Fpii\u002FS1524904220301168\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">virtual reality\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, can also serve cancer patients in pain reduction by distracting the patients. Although the \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC7226660\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">effectiveness of adjunctive therapy\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> is not entirely measurable, respondents found the therapy to be beneficial.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>\u003Cb>These technologies show a glimpse into the future – and in some cases, that future is here already. We need to keep on pushing the limits to get to a stage where the diagnosis of cancer is not a life-altering event that often brings an untimely end to a patient’s life, but at least a manageable, chronic condition\u003C\u002Fb>.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n\n\n\n\u003Cp>\u003C\u002Fp>\n",{"rendered":835,"protected":16},"\u003Cp>We listed devices and technologies with the promise of curing cancer or transforming it into a manageable chronic disease. \u003C\u002Fp>\n",34685,{"_acf_changed":16,"footnotes":64},[839,840,691,280,841,692,441,5,693,842,694,843,442,844,695,696],6479,6261,798,499,507,497,[80,846,847,848,849,850,851,852,853,854,855,856,857,858,859,860,861,862,863,864,865,866,867,868],7161,7163,7165,545,7167,567,7169,606,7171,976,6041,658,7173,1137,7175,1463,821,7177,163,6999,7179,259,7157,[709,710,711,452,453,870,871],952,953,[],[456,107,874,457,585,875,876,101],2255,5499,1621,[878,53,116,117,118,119,120,879,880,721,314,881,722,461,123,723,882,724,883,462,884,725,726,133,885,886,887,888,889,890,891,892,893,894,895,896,897,898,899,900,901,902,903,904,905,906,907,737,738,739,470,471,908,909],"post-12808","category-covid-19","category-forecast","category-digital-health-research","category-healthcare-design","category-nanotechnology","category-portable-diagnostics","tag-joe-biden","tag-cancer-moonshot","tag-barack-obama","tag-sensors","tag-fluid-biopsy","tag-in-silico-trials","tag-targeted-therapies","tag-prevention","tag-molecular-diagnostics","tag-biomarkers","tag-covid-19","tag-oncology","tag-oncompass","tag-dante-labs","tag-dna-cages","tag-atlas-biomed","tag-a-i","tag-precision-surgery","tag-cancer-2","tag-mrna","tag-quell","tag-genetic-testing","tag-poct","project_category-policy-makers","project_category-researchers",{"id":836,"alt_text":64,"caption":64,"description":911,"media_type":149,"media_details":912,"post":929,"source_url":930},"The future of cancer care",{"width":332,"height":333,"file":913,"sizes":914,"image_meta":928},"2021\u002F06\u002Ftmf_article_273-01.png",{"medium":915,"large":918,"thumbnail":921,"medium_large":924,"1536x1536":925},{"file":916,"width":179,"height":180,"mime-type":338,"source_url":917},"tmf_article_273-01-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F06\u002Ftmf_article_273-01-370x208.png",{"file":919,"width":182,"height":183,"mime-type":338,"source_url":920},"tmf_article_273-01-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F06\u002Ftmf_article_273-01-768x432.png",{"file":922,"width":177,"height":177,"mime-type":338,"source_url":923},"tmf_article_273-01-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F06\u002Ftmf_article_273-01-150x150.png",{"file":919,"width":182,"height":183,"mime-type":338,"source_url":920},{"file":926,"width":349,"height":350,"mime-type":338,"source_url":927},"tmf_article_273-01-1536x864.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F06\u002Ftmf_article_273-01-1536x864.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},34659,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F06\u002Ftmf_article_273-01.png",{"subtitle":64,"cta_type":364,"cta_color":64,"related_posts_footer":932,"related_posts":16,"related_books":936,"key_takeaways":940},[933,934,935],24858,51747,51875,[937,938,939],47427,34151,24764,[941,943],{"title":942},"\u003Cp>Early and precise cancer detection is being revolutionized through innovations like liquid biopsy and AI-powered tools.\u003C\u002Fp>\n",{"title":944},"\u003Cp>These technologies are pushing towards making cancer a chronic, rather than life-ending, condition.\u003C\u002Fp>\n",{"yoast_wpseo_title":946,"yoast_wpseo_metadesc":947,"yoast_wpseo_canonical":829},"13 Technologies That Will Shape The Future of Cancer Care","The devices and technologies with the promise of curing cancer or transforming it into a manageable chronic disease. Here are 13 promising technologies.",{"self":949,"collection":954,"about":956,"author":958,"replies":960,"version-history":963,"predecessor-version":967,"wp:featuredmedia":971,"wp:attachment":974,"wp:term":977,"curies":988},[950],{"href":951,"targetHints":952},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F12808",{"allow":953},[27],[955],{"href":220},[957],{"href":223},[959],{"embeddable":41,"href":226},[961],{"embeddable":41,"href":962},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=12808",[964],{"count":965,"href":966},40,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F12808\u002Frevisions",[968],{"id":969,"href":970},58693,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F12808\u002Frevisions\u002F58693",[972],{"embeddable":41,"href":973},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F34685",[975],{"href":976},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=12808",[978,980,982,984,986],{"taxonomy":11,"embeddable":41,"href":979},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=12808",{"taxonomy":248,"embeddable":41,"href":981},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=12808",{"taxonomy":251,"embeddable":41,"href":983},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=12808",{"taxonomy":254,"embeddable":41,"href":985},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=12808",{"taxonomy":257,"embeddable":41,"href":987},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=12808",[989],{"name":39,"href":40,"templated":41},{"id":991,"date":992,"date_gmt":993,"guid":994,"modified":996,"modified_gmt":997,"slug":998,"status":52,"type":53,"link":999,"title":1000,"content":1002,"excerpt":1004,"author":61,"featured_media":1006,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1007,"categories":1008,"tags":1009,"project_category":1019,"contact_email_category":1020,"yst_prominent_words":1021,"class_list":1037,"better_featured_image":1048,"acf":1075,"yoast_meta":1087,"_links":1090},15713,"2024-08-29T09:30:17","2024-08-29T07:30:17",{"rendered":995},"http:\u002F\u002Fmedicalfuturist.com\u002F?p=15713","2024-08-29T17:02:09","2024-08-29T15:02:09","top-companies-genomics","https:\u002F\u002Fmedicalfuturist.com\u002Ftop-companies-genomics",{"rendered":1001},"Top Companies in Genomics",{"rendered":1003,"protected":16},"\n\u003Cp>From portable genome sequencers to genetic tests revealing distant relations with Thomas Jefferson, genomics represents a fascinatingly innovative area of healthcare. As the price of genome sequencing has been in free fall for years, the start-up scene is bursting with transformative power. Let’s look at some of the most amazing genomics companies!\u003C\u002Fp>\n\n\n\n\u003Cp>Important note: I first created a similar list seven years ago. It is very visible that companies in this sector come and go. Regulatory hurdles are complex, and the markets themselves are still learning how to fully harness the power of genetic information. In many cases, the potential applications of genomic data remain unclear, creating uncertainty about the best ways to integrate this knowledge into healthcare and daily life.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">The amazing journey of genome sequencing\u003C\u002Fh2>\n\n\n\n\u003Cp>Genome sequencing has been on an amazing scientific as well as economic journey for the last three decades. The \u003Ca href=\"https:\u002F\u002Funlockinglifescode.org\u002Ftimeline?tid=4\">Human Genome Project\u003C\u002Fa> began in 1990 with the aim of mapping the whole structure of the human genome and sequencing it. The bold and daring project took 13 years and an insanely huge amount of money, approximately $2.7 billion for the US government, to complete. Since then, the volume of genetic information has multiplied exponentially, and the ability to access that data has become widely available to consumers. Today, people can order genetic tests online to learn about their ancestry, health predispositions, and even have their entire genome sequenced—all for a fraction of what it once cost.\u003C\u002Fp>\n\n\n\n\u003Cp>The landscape has evolved significantly since 2015 when DeCode Genetics in Iceland \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.technologyreview.com\u002Fs\u002F536096\u002Fgenome-study-predicts-dna-of-the-whole-of-iceland\u002F\" target=\"_blank\">collected full DNA sequences\u003C\u002Fa> on 10,000 individuals, allowing them to extrapolate the genetic makeup of nearly the entire Icelandic population. This feat, once considered mind-blowing, has been surpassed by more recent achievements. \u003C\u002Fp>\n\n\n\n\u003Cp>For instance, the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ukbiobank.ac.uk\u002Fenable-your-research\u002Fabout-our-data\" target=\"_blank\">UK Biobank\u003C\u002Fa> has sequenced the genomes of 500,000 participants, while the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fallofus.nih.gov\u002F\" target=\"_blank\">All of Us Research Program\u003C\u002Fa> in the US aims to gather genetic data from one million people.\u003C\u002Fp>\n\n\n\n\u003Cp>The cost of sequencing has continued to decrease. In January 2017, DNA sequencing giant \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.illumina.com\u002Fsystems\u002Fsequencing-platforms\u002Fnovaseq\u002Fintroduction.html#.WHVn1LYrKqA\" target=\"_blank\">Illumina\u003C\u002Fa> \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Ftechcrunch.com\u002F2017\u002F01\u002F10\u002Fillumina-wants-to-sequence-your-whole-genome-for-100\u002F\" target=\"_blank\">unveiled a new machine\u003C\u002Fa> that the company says is “expected one day” to order up your whole genome for less than $100 As of 2023, some companies offer whole-genome sequencing for around $200, with projections of sub-$100 sequencing on the horizon. Furthermore, the applications of genomics have expanded beyond ancestry and health predictions. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-state-of-crispr-clinical-trials-and-their-future-potentials\" target=\"_blank\">CRISPR gene-editing technology\u003C\u002Fa> has opened new frontiers in treating genetic diseases, and pharmacogenomics is revolutionizing personalized medicine.\u003C\u002Fp>\n\n\n\n\u003Cp>Considering all that, did you arrive at the thought of establishing a genomics start-up right now? Well, before doing so, it is generally advised to analyze the market and your future competition, so here is my list of the most successful genomics companies!\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"Everything About Genetic Testing \u002F Episode 1 - The Medical Futurist\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FOzjbfRkhsEo?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">1) Personal genomics\u003C\u002Fh2>\n\n\n\n\u003Cp>I had several genetic tests in my life: you can read about my experiences with Navigenics, Pathway Genomics, Gentle Labs, and Futura Genetics here. For me, as a geneticist, it is simply amazing that I can order a genetic test online, and within a few weeks, I can hold the results in my hand. The basic assumption is that with the possibility of direct-to-consumer (DTC) genetic testing anyone can order a test from home, and learn about their risks for medical conditions. The testing process is everywhere more or less the same. The companies send you a kit to collect your sample. After you send it back, they examine it; and after quite some time you get your genuine report online.\u003C\u002Fp>\n\n\n\n\u003Cp>Despite \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.raps.org\u002Fnews-and-articles\u002Fnews-articles\u002F2015\u002F11\u002Ffda-warns-three-companies-over-dtc-genetic-tests\" target=\"_blank\">some regulatory issues with the FDA\u003C\u002Fa>, more and more personal genomics companies were trying to bring genomics to the hands of patients in the past decade, but it also came with great fluctuation. Many of the companies I tried in the past few years (like Pathway Genomics, Navigenics or the Belgian Gentle Labs) disappeared, and many changed profiles. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">a)\u003Cstrong> \u003C\u002Fstrong>\u003Ca href=\"https:\u002F\u002Fmediacenter.23andme.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">23andme\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The most popular and one of the “oldest” personal genetics company, established in 2006, offers easy and affordable access to genetic information. Its name comes from the fact that human DNA is organized into 23 pairs of chromosomes. The Mountainview-based 23andme has already built up the biggest database of patients’ DNA information with more than 5,000,000 customers and one billion phenotypic data points!\u003C\u002Fp>\n\n\n\n\u003Cp>Originally, the company offered services to tell anyone their likelihood to get certain diseases, as well as information about their family tree, however, in 2014 the FDA restricted 23andme’s operations saying that the health information services were not clear or complete enough for customers. So, the genetic testing company scaled back its activity mostly to provide data about ancestry. They have also \u003Ca href=\"http:\u002F\u002Fwww.greensboro.com\u002Fnews\u002Flocal_news\u002Fsisters-find-each-other-through-dna-analysis\u002Farticle_e280fbab-74ab-50c0-b327-20770f646f42.html\">linked together long-lost family members\u003C\u002Fa> and have built family trees. In April 2017, however, \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002F2017\u002F04\u002F23andme-won-back-right-foretell-diseases\u002F\">the FDA re-approved 23andme’s services\u003C\u002Fa>, which aim to tell people to which diseases they are susceptible. Confusingly enough, the company still only offers ancestry information to most global clients, although you can order the health info if you are a US, UK, Canadian, Danish, Finnish, Swedish, Dutch or Irish. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"23andMe: Incredible You\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002Fzeo7zPzZwIk?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">b)\u003Cstrong> \u003C\u002Fstrong>\u003Ca href=\"http:\u002F\u002Ffuturagenetics.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Futura Genetics\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The Prague-based company established in 2014 originally offered a DNA test on predisposition for 28 most common diseases such as lung cancer, lupus, melanoma, migraine, Alzheimer’s disease, breast or bladder cancer. When I tried their services, Futura Genetics found that I have a higher risk of melanoma and basal cell carcinoma. So, they recommended I wear sunscreen all the time when I’m out there.\u003C\u002Fp>\n\n\n\n\u003Cp>Fast forward a few years and the company has changed focus, now they help insurance companies use people’s genetic and lifestyle information to create personalized health plans.  They use people’s genetic information to help them live healthier and longer lives, and, at the same time, it gives insurance companies useful data about their customers’ health risks, without breaking any laws or revealing private genetic information.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">c) \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.veritasgenetics.com\u002F\" target=\"_blank\">Veritas Genetics\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The Massachusetts-based company established in 2014 was co-founded by the guru of modern genomics, George Church. One year later, he made whole-genome sequencing available to about 5,000 participants in the Personal Genome Project (PGP) at Harvard Medical School. Veritas runs its tests in a CLIA-certified lab and it also requires an order from your doctor first before sequencing your genome.\u003C\u002Fp>\n\n\n\n\u003Cp>Veritas Genetics has been \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.xconomy.com\u002Fboston\u002F2016\u002F10\u002F17\u002Fveritas-genetics-lands-30m-for-1000-genome-sequencing\u002F\" target=\"_blank\">ha\u003C\u002Fa>iled as the first company to be able to sequence, analyze, and interpret the human genome for less than $1,000 –  well to be precise for $999, to properly feed the marketing machines as well. In 2016, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Ftechcrunch.com\u002F2016\u002F03\u002F08\u002Fyou-can-now-pull-up-your-entire-genome-for-under-1000-on-your-smartphone\u002F\" target=\"_blank\">Veritas sa\u003C\u002Fa>id to Techcrunch that its myGenome product would even go one step further: it promised to bring the entire set of DNA test results to your smartphone. The cost includes test results and the benefit of genetic counseling to help you decipher what those results mean for your health.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"815\" height=\"430\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fveritas-genetics_george-church_genomics.jpg\" alt=\"Veritas Genetics - George Church\" class=\"wp-image-15715\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fveritas-genetics_george-church_genomics.jpg 815w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fveritas-genetics_george-church_genomics-768x405.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fveritas-genetics_george-church_genomics-512x270.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fveritas-genetics_george-church_genomics-458x242.jpg 458w\" sizes=\"auto, (max-width: 815px) 100vw, 815px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>As of now, you can access their tests through your doctor’s prescription, although they website encourages everyone without a prescribing doctor to contact them as they will still be able to help. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">d) \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmyriad.com\u002F\" target=\"_blank\">Myriad\u003C\u002Fa> (formerly Counsyl)\u003C\u002Fh3>\n\n\n\n\u003Cp>The \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.technologyreview.com\u002Flists\u002Fcompanies\u002F2015\u002F#counsyl\" target=\"_blank\">MIT Technology Review said\u003C\u002Fa> 3.6% of all wannabe parents in the US used Counsyl’s genetic test before trying to have a baby in 2015. This was amazing statistical data for the company, which started to sell DTC genetic tests a decade earlier and was established by a group of friends at Stanford. The South San Francisco-based \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.nytimes.com\u002F2010\u002F01\u002F29\u002Fbusiness\u002F29gene.html\" target=\"_blank\">Counsyl was selling a test \u003C\u002Fa>they claimed could tell couples whether they are at risk of having children with a range of inherited diseases, including cystic fibrosis, Tay-Sachs, spinal muscular atrophy, sickle cell disease, and Pompe disease. Once informed, Counsyl said, couples can take steps like using in vitro fertilization with genetic testing of the embryos, to avoid bearing children who would have the diseases, many of which are incurable and fatal in childhood.\u003C\u002Fp>\n\n\n\n\u003Cp>A lot has changed in the past ten years, Myriad Genetics acquired Counsyl in 2018, and you can’t buy their tests directly anymore, you need a prescribing physician as a main rule. Although they offer a self-paying process for cancer risks for example, it includes multiple virtual appointments for almost 200 dollars each, so maybe it’s best to look for a doctor.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"353\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcounsyl_genetics.jpg\" alt=\"genomics companies\" class=\"wp-image-15717\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcounsyl_genetics.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcounsyl_genetics-768x312.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcounsyl_genetics-512x208.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcounsyl_genetics-458x186.jpg 458w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">2) Pharmacogenomics\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC2014592\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Pharmacogenetics\u003C\u002Fa> is defined as the study of variability in drug response due to the genetic code. It argues that despite general sentiments, medications do not have the same effect on people. It is the answer to why some people cannot drink coffee after 6 pm otherwise they cannot sleep; and why others might have some double espresso at 11 pm and sleep around midnight as if nothing happened. Pharmacogenomics is viewed as a highly important area for improving drug therapy and prescriptions in the future. As the research on the effect of genetics on drug response is intensifying, so is the number of start-ups, who are leveraging on the results.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">a) \u003Ca href=\"https:\u002F\u002Fwww.mydna.life\u002F\">MyDNA\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The Australian genetics company previously known as GenesFX was founded in 2007 by Leslie Sheffield, who has been researching pharmacogenomics since the 1980s. The company’s medication test promises to help you and your doctor personalize your treatment by selecting the most appropriate medications based on how your body metabolizes drugs, and the doses that might work best with you. Anyone is able to \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.mydna.life\u002Forder-online\u002F\" target=\"_blank\">order a test online\u003C\u002Fa> for $198.\u003C\u002Fp>\n\n\n\n\u003Cp>I already shared my experience with the test \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fmydna-review\u002F\" target=\"_blank\">here\u003C\u002Fa>. It turned out that if I have to take Codeine (an opiate used to treat pain); fluvoxamine (used to treat obsessive-compulsive disorder); or simvastatin (used to lower cholesterol), I will have major side effects from cardiomyopathy to liver problems.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"497\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fmydna_pharmacogenomics_genomics.jpg\" alt=\"genomics companies\" class=\"wp-image-15718\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fmydna_pharmacogenomics_genomics.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fmydna_pharmacogenomics_genomics-768x439.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fmydna_pharmacogenomics_genomics-512x292.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fmydna_pharmacogenomics_genomics-438x250.jpg 438w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Ca href=\"\">\u003C\u002Fa>3) Genomics combined with Artificial Intelligence\u003C\u002Fh2>\n\n\n\n\u003Cp>The genomics companies below use deep learning to mine vast amounts of genetic information for new clues about disease, diagnosis or treatment and combine the amazing potential in AI and genetics for opening new horizons in healthcare.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">a) \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.deepgenomics.com\u002F\" target=\"_blank\">Deep Genomics\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>Brendan Frey’s company promises to solve the biggest puzzle in genetics. To get to know exactly what information most of the genome could provide. For doing so, Deep Genomics is \u003Ca href=\"http:\u002F\u002Fwww.businessinsider.com\u002Fhow-deep-genomics-is-using-ai-to-solve-genetic-mysteries-2015-9\" target=\"_blank\" rel=\"noreferrer noopener\">leveraging AI, specifically deep learning to help decode the meaning of the genome\u003C\u002Fa>. Their learning software is developing the ability to try and predict the effects of a particular mutation based on its analyses of hundreds of thousands of examples of other mutations; even if there’s not already a record of what those mutations do.\u003C\u002Fp>\n\n\n\n\u003Cp>So far, Deep Genomics has used their computational system to develop a database that provides predictions for how more than 300 million genetic variations could affect a genetic code. For this reason, their findings are used for genome-based therapeutic development, molecular diagnostics, targeting biomarker discovery and assessing risks for genetic disorders.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"359\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdeep-genomics.jpg\" alt=\"Deep Genomics\" class=\"wp-image-15719\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdeep-genomics.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdeep-genomics-768x317.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdeep-genomics-512x211.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdeep-genomics-458x189.jpg 458w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">b) \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.vergegenomics.com\" target=\"_blank\">Verge Genomics\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The San Francisco-based company was originally established to find cures first of all for brain diseases with the help of genetic data. Verge Genomics \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Ftechcrunch.com\u002F2015\u002F11\u002F03\u002Fverge-genomics-on-a-quest-to-solve-neurodegenerative-disorders-picks-up-4m-seed\u002F\" target=\"_blank\">worked on creating algorithms that make pharmaceutical creation far more efficient\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cp>However, the company has changed its approach and has become a drug discovery platform. Their first drug, called VRG50635, has entered the clinic for amyotrophic lateral sclerosis (ALS). It was discovered by Converge, the company’s AI-powered platform, moving from research to clinic in just four years. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.vergegenomics.com\u002Fpipeline\" target=\"_blank\">Other running projects\u003C\u002Fa> are targeting potential treatments for Parkinson’s Disease, Schizophrenia, and Crohn’s Disease among others\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">c) \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fverily.com\u002F\" target=\"_blank\">Verily Life Sciences\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fverily.com\u002F\" target=\"_blank\">Verily Life Sciences\u003C\u002Fa>, formerly known as Google Life Sciences was founded in 2015 under the auspices of Google’s umbrella corporation, Alphabet. It is \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Ffortune.com\u002F2016\u002F04\u002F22\u002Fjessica-mega-google-medical-verily\u002F\" target=\"_blank\">working on its genetic data-collecting initiative\u003C\u002Fa>, the Baseline Study. It aims to use some of the same algorithms that power Google’s famous search button in order to analyse what makes people healthy.\u003C\u002Fp>\n\n\n\n\u003Cp>In January 2017, the company received $800 million investment from a Singapore-based investment company, Temasek for successfully continuing its research in areas such as the Personalized Parkinson’s Project, which is investigating patterns in the disease’s progression and identifying the building blocks for a potential cure. While Verily is involved in various sensor and healthcare tool platform projects, it also works on projects such as the DeepVariant. In the latter, Verily and Google are working together so that you can run the DeepVariant germline variant calling algorithm on human whole genome sequencing data on \u003Ca href=\"https:\u002F\u002Fcloud.google.com\u002Fgenomics\" target=\"_blank\" rel=\"noreferrer noopener\">Google Genomics\u003C\u002Fa>, powered by the \u003Ca href=\"https:\u002F\u002Fcloud.google.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Google Cloud Platform\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>In 2023 the company \u003Ca href=\"https:\u002F\u002Fverily.com\u002Fperspectives\u002Fverily-viewpoint-workbench-accelerate-biomedical-research\" target=\"_blank\" rel=\"noreferrer noopener\">launched Viewpoint Workbench\u003C\u002Fa>, a new enterprise-grade platform to unify multimodal data and accelerate biomedical research. It is a collaborative environment for data generators, research, and biopharma organizations to govern and analyze their data..\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">d) \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.decode.com\u002F\" target=\"_blank\">DeCODE\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The Reykjavík-based DeCODE, founded in 1996, has discovered genetic risk factors for dozens of diseases, ranging from cardiovascular disease to cancer, as well as collected full DNA sequences on 10,000 individuals living on the island. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"434\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdecode-genetics_genomics.jpg\" alt=\"DeCode Genetics\" class=\"wp-image-15720\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdecode-genetics_genomics.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdecode-genetics_genomics-768x383.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdecode-genetics_genomics-512x255.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fdecode-genetics_genomics-458x229.jpg 458w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>However, the road to success was far from easy. By the end of 2009, \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002F2009\u002F08\u002Fdecode-genetics-on-the-brink-of-insolvency\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">the enterprise was on the brink of insolvency\u003C\u002Fa> and had to fight for survival. In 2012, DeCODE’s financial situation was resolved as biotech pioneer Amgen Inc., in a bid for a big edge in using people’s genetic information to find better ways to attack diseases, bought up the company for $415 million.\u003C\u002Fp>\n\n\n\n\u003Cp>In the past decade, deCODE has discovered key genetic risk factors for dozens of common diseases ranging from \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.decode.com\u002Fvariants-in-the-genome-interact-with-each-other-and-with-the-environment-to-affect-risk-of-cardiovascular-disease\u002F\" target=\"_blank\">cardiovascular disease\u003C\u002Fa> to \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.decode.com\u002Frare-sequence-variants-that-are-associated-with-a-high-risk-of-parkinsons-disease\u002F\" target=\"_blank\">Parkinson’s disease\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">4) Precision Oncology\u003C\u002Fh2>\n\n\n\n\u003Cp>According to the \u003Ca href=\"https:\u002F\u002Fghr.nlm.nih.gov\u002Fprimer\u002Fprecisionmedicine\u002Fdefinition\" target=\"_blank\" rel=\"noreferrer noopener\">National Institutes of Health (NIH)\u003C\u002Fa>, precision oncology is “an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment and lifestyle for each person.” This approach will allow doctors and researchers to predict more accurately which treatment and prevention strategies for a particular disease will work in which groups of people. \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fprecision-medicine-best-hope-fight-cancer\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Precision medicine is our best hope against cancer\u003C\u002Fa>, and the following genomics companies will enable it.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">a) \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.foundationmedicine.com\u002F\" target=\"_blank\">Foundation Medicine\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The Massachusetts-based molecular information company develops, manufactures and sells genomic analysis diagnostics for solid and circulating cancers. Foundation Medicine \u003Ca href=\"http:\u002F\u002Fwww.businesswire.com\u002Fnews\u002Fhome\u002F20170206005255\u002Fen\" target=\"_blank\" rel=\"noreferrer noopener\">offers a full suite of comprehensive genomic profiling assays\u003C\u002Fa> to identify the molecular alterations in a patient’s cancer and match them with relevant targeted therapies, immunotherapies and clinical trials. The venture’s molecular information platform aims to improve day-to-day care for patients by serving the needs of clinicians, academic researchers and drug developers to help advance the science of molecular medicine in cancer.\u003C\u002Fp>\n\n\n\n\u003Cp>Foundation Medicine went public in August 2013, and two years later \u003Ca href=\"http:\u002F\u002Fwww.reuters.com\u002Farticle\u002Fus-foundation-roche-idUSKBN0KL0D420150112\" target=\"_blank\" rel=\"noreferrer noopener\">Roche Holding acquired majority stake in the company\u003C\u002Fa>, signaling its determination to expand in cancer immunotherapy as well as the viability of precision medicine for the future of cancer treatment.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">b) \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.color.com\u002F\" target=\"_blank\">Color Genomics\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The Silicon Valley start-up, Color Genomics aims to democratize access to DNA testing through affordable and clinical-grade genetic tests. It focuses on testing for mutations that can lead to a higher risk for cancers, like ovarian, breast, prostate, and colon cancer. The company charges $249 for their extended common hereditary cancers test which also includes the risk assessment for common hereditary heart conditions and a medication response genetic test. \u003C\u002Fp>\n\n\n\n\u003Cp>It was a huge step forward when in 2017 \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.color.com\u002Fblog\u002Fa-big-step-forward-in-helping-people-understand-their-genes\" target=\"_blank\">Color began accepting insurance for patients\u003C\u002Fa>, so the clinical-grade genetic test, the Color Test was covered by some of the largest insurance companies in the US, collectively representing more than 100 million people. Now the company works with not only direct consumers but also with employers, unions, and health plans. They partnered with the American Cancer Society to improve access and uptake for recommended cancer screenings in 2023.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"We are much more similar than we are different\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FVdetAEuyjA4?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">c) \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.questdiagnostics.com\u002Fhome.html\" target=\"_blank\">Quest Diagnostics\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The Fortune 500 company is one of the oldest clinical laboratory developing together with medical technology throughout the decades. The New Jersey-based Quest Diagnostics was originally established in 1967 as Metropolitan Pathology Laboratory, and by now it has more than 40,000 employees. It offers access to diagnostic testing services for cancer, cardiovascular disease, infectious disease and neurological disorders.\u003C\u002Fp>\n\n\n\n\u003Cp>In the last decade, \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fnewsroom.questdiagnostics.com\u002F2016-05-26-Quest-Diagnostics-Launches-Three-Genetic-Test-Panels-for-Predicting-Hereditary-Cancer-Risk\" target=\"_blank\">Quest Diagnostics gradually moved into precision diagnostics\u003C\u002Fa>, and developed a number of genetic tests from individual risks of hereditary cancers to cardiognetic testing. The company also provides services in pharmacogenomics: their \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.questdiagnostics.com\u002Fhealthcare-professionals\u002Fabout-our-tests\u002Fcardiovascular\u002Fnon-lipid-markers-cvd\u002Fimportant-genotyping\" target=\"_blank\">AccuType CP\u003C\u002Fa> test was the first cardiovascular disease test to identify a patient’s response to an anti-clotting drug.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"Quest Diagnostics 50th Anniversary: 1967-2017\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FLhI5NZK3fBo?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">5) Genetic ancestry\u003C\u002Fh2>\n\n\n\n\u003Cp>One of the most fun areas of genomics is to get to know where your family comes from. Are you a distant relative of Helen of Troy? Was your grand-grand-grandfather fighting together with Garibaldi for the Republic of Italy? Was your grand-grandmother listening to Gandhi’s talks in India? According to my Pathway Genomics genetic test, I am distantly related to Benjamin Franklin, which is kind of cool. So, let’s see the genomics companies exclusively occupied with telling you your very own history.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">a) \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ancestry.com\u002F\" target=\"_blank\">Ancestry\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>It is one of the largest genealogy companies in the world: as of 2014, \u003Ca href=\"http:\u002F\u002Fwww.baselinemag.com\u002Fanalytics-big-data\u002Fmanaging-securing-data-for-the-worlds-families.html#sthash.2qtoStwA.dpuf\" target=\"_blank\" rel=\"noreferrer noopener\">it had a 10 petabyte database with 13 billion structured and unstructured records\u003C\u002Fa> going back to the 1300s. A number that grew by 1.2 billion documents in 2013. Three years ago, the database had DNA from more than 300,000 people, who got information on which of the 26 regions of the world their ancestors came from, and these numbers are surely growing exponentially ever since.\u003C\u002Fp>\n\n\n\n\u003Cp>Originally \u003Ca href=\"https:\u002F\u002Fen.wikipedia.org\u002Fwiki\u002FAncestry.com\">starting as a genealogy newsletter in 1983\u003C\u002Fa>, and a year later as an established publishing company, by now it also offers genealogical DNA tests through AncestryDNA. You can trace your family tree, figure out which region your family comes from or where do your distant relatives live.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"Momondo: The DNA Journey | Ancestry\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFw7FhU-G1_Q?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">b) \u003Ca href=\"https:\u002F\u002Fwww.myheritage.com\u002Fdna\" target=\"_blank\" rel=\"noreferrer noopener\">MyHeritage\u003C\u002Fa> \u003C\u002Fh3>\n\n\n\n\u003Cp>The company offers a comprehensive DNA test that helps individuals explore their family history, uncover distant relatives, and trace their ethnic origins. The test provides insights into over 2,100 geographic regions worldwide, making it a valuable tool for those seeking to understand their roots. MyHeritage’s platform also integrates with an extensive database of historical records, enabling users to build detailed family trees and discover new connections with relatives from across the globe.\u003C\u002Fp>\n\n\n\n\u003Cp>At the time of writing, it \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.myheritage.com\u002Fdna\" target=\"_blank\">was also super affordable\u003C\u002Fa>: the test only cost EUR 35 plus shipping, probably one of the most cost-effective DNA testing available. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">6) Bioinformatics and technology enabling genome sequencing\u003C\u002Fh2>\n\n\n\n\u003Cp>I already mentioned that the cost of genome sequencing has been in free fall ever since the completion of the Human Genome Project, but I have not yet talked about the genomics companies pushing down that very cost by developing better and better biomedical equipment or making the bioinformatics process more and more accurate.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">a) \u003Ca href=\"https:\u002F\u002Fwww.illumina.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Illumina\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>By far the biggest player on the technological side of the genome sequencing market is Illumina. The MIT Technology Review named it the world’s smartest company in 2014. It provides a line of products and services that serve the genome sequencing, genotyping and gene expression markets helping to drop the price by many zeros. \u003C\u002Fp>\n\n\n\n\u003Cp>Beyond offering genome sequencers as well as whole genome sequencing through healthcare professionals, the San Diego-based company, established in 1998, also \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.illumina.com\u002Fproducts\u002Fby-area\u002Foncology.html?tags=&pageSize=20&pageNumber=1&sortBy=title\" target=\"_blank\">offers\u003C\u002Fa> precision oncology solutions, such as the examination of known mutations in cancer-related genes. The company also formed a spin-off called \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.bio-itworld.com\u002F2016\u002F1\u002F11\u002Fillumina-spinoff-grail-trial-liquid-biopsies-early-detection-cancer.html\" target=\"_blank\">GRAIL to experiment with liquid biopsy\u003C\u002Fa>, a blood test to detect all types of cancer from a very early stage. In 2023, the final results from the Pathfinder multi-cancer early detection blood test \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fgrail.com\u002Fpress-releases\u002Ffinal-results-from-pathfinder-study-of-grails-multi-cancer-early-detection-blood-test-published-in-the-lancet\u002F\" target=\"_blank\">were published in the Lancet\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"Envisioning how genomics will improve human health | Illumina Video\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002F6an5U-Fpc5o?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">b) \u003Ca href=\"https:\u002F\u002Fnanoporetech.com\u002F\">Nanopore Technologies\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The UK-based start-up, \u003Ca href=\"https:\u002F\u002Fnanoporetech.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Oxford Nanopore Technologies\u003C\u002Fa> does not settle for comfortable genetic testing carried out in laboratories, but it promises to make genome sequencing mobile and portable with the help of nanopore technology. It offers real-time, out-of-the-lab DNA sequencing, as Nanopore’s team has developed the world’s first and only DNA sequencer. The device is in use by a thriving community of scientists in more than 50 countries, which for example made possible to \u003Ca href=\"https:\u002F\u002Fnanoporetech.com\u002Fresource-centre\u002Freal-time-dna-sequencing-antarctic-dry-valleys-using-oxford-nanopore-sequencer\" target=\"_blank\" rel=\"noreferrer noopener\">carry out offline DNA sequencing of environmental samples on Antarctica\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>The company, established in 2005 as a spin-out from the University of Oxford now has over a thousand employees, and apart from the Oxford Science Park HQ, it has satellite offices in Cambridge (UK), New York, Cambridge, San Francisco (US), Singapore, Shanghai, Beijing, and commercial presence in Japan, Germany, France and India. The company sells to more than 120 countries.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">c) \u003Ca href=\"https:\u002F\u002Fwww.bgi.com\u002Fglobal\" target=\"_blank\" rel=\"noreferrer noopener\">BGI\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The biggest Chinese conglomerate aiming to elevate genome sequencing and bioinformatics to a whole new level. The company is headquartered in Shenzhen, China, with branches and medical laboratories all over Europe, North America and the Asia Pacific region. BGI, short for Beijing Genomics Institute prior to 2008, currently operates in more than 100 countries and regions and works with more than 3000 medical institutions and more than 300 hospitals.\u003C\u002Fp>\n\n\n\n\u003Cp>Beyond offering human, plant, and animal DNA sequencing services to empower genomics research, BGI developed its own sequencing platforms.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"653\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fbgi-china_genomics.jpg\" alt=\"BGI China_Genomics companies\" class=\"wp-image-15722\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fbgi-china_genomics.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fbgi-china_genomics-768x576.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fbgi-china_genomics-512x384.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fbgi-china_genomics-333x250.jpg 333w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">7) CRISPR\u003C\u002Fh2>\n\n\n\n\u003Cp>CRISPR is the newest, most efficient and most accurate method to edit a cell’s genome – it was only invented in 2012! However, as it opens up a myriad of wonderful opportunities as well as frightening ethical challenges in healthcare, there are already numerous start-ups experimenting with it. (I summarized its revolutionary potential \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhat-can-you-achieve-with-crispr-therapy\u002F\" target=\"_blank\">here\u003C\u002Fa> and we also analyzed the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-state-of-crispr-clinical-trials-and-their-future-potentials\u002F\" target=\"_blank\">state and potential of ongoing CRISPR trials\u003C\u002Fa> as of the end of 2023.) In 2016, CRISPR got a green light for clinical trials from the US National Institutes of Health, and in November 2023 the first CRISPR gene editing therapy, called Casgevy was approved for the treatment of patients with transfusion-dependent β-thalassemia and the treatment of sickle cell disease. \u003C\u002Fp>\n\n\n\n\u003Cp>In the future, it might become the ultimate weapon against cancer, malaria or genetic disorders. Let’s look at the genomics companies working for a better, more disease-free future.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">a) \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.crisprtx.com\u002F\" target=\"_blank\">CRISPR Therapeutics\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>The Swiss company was co-founded in 2013 by Emmanuelle Charpentier, whose research unveiled the key mechanisms of the CRISPR\u002FCas9 technology. CRISPR Therapeutics established strategic collaborations with Bayer AG and Vertex Pharmaceuticals to develop CRISPR-based treatments for diseases with high unmet need.\u003C\u002Fp>\n\n\n\n\u003Cp>The research team announced almost a decade ago that they are working on using CRISPR technology in the treatment of beta-thalassemia, sickle cell disease, Hurler syndrome, severe combined immunodeficiency (SCID), immuno-oncology, haemophilia, cystic fibrosis or Duchenne muscular dystrophy. And they were \u003Ca href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fd41587-023-00016-6\" target=\"_blank\" rel=\"noreferrer noopener\">the first to cross the finishing line with Casgevy\u003C\u002Fa>, which is, as we already mentioned, the first regulatory-approved CRISPR therapy. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">b) \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.intelliatx.com\" target=\"_blank\">Intellia Therapeutics\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>Intellia is a leading genome editing company currently in the discovery phase, focused on the development of proprietary, potentially curative therapeutics using the CRISPR\u002FCas9 system to treat people living with severe and life-threatening diseases. The name of the company derives from the Greek word, Entelia, meaning a situation of excellence; without any faults. Considering the fact that Jennifer Doudna, the researcher having led the team that developed the application of CRISPR\u002FCas9 and its use as a tool for genome engineering, is the initiator of Intellia, the start-up will probably live up to its name.\u003C\u002Fp>\n\n\n\n\u003Cp>The company has a pipeline of several ongoing projects, the most advanced is the therapy for Transthyretin Amyloidosis in \u003Ca href=\"https:\u002F\u002Fwww.intelliatx.com\u002Fpipeline\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">late-stage clinical trials\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"508\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fintellia-therapeutics_genomics.jpg\" alt=\"Intellia Therapeutics\" class=\"wp-image-15723\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fintellia-therapeutics_genomics.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fintellia-therapeutics_genomics-768x448.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fintellia-therapeutics_genomics-512x299.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fintellia-therapeutics_genomics-428x250.jpg 428w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">c)\u003Cstrong> \u003C\u002Fstrong>\u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.editasmedicine.com\" target=\"_blank\">Editas Medicine\u003C\u002Fa>\u003C\u002Fh3>\n\n\n\n\u003Cp>In 2013, several of the scientists credited with discovering and developing CRISPR joined forces to establish what is now called Editas Medicine, for example, Feng Zhang, George Church or Jennifer Doudna. It is Zhang, who has ownership over the CRISPR patent, but \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.researchgate.net\u002Ffigure\u002FTimeline-of-the-CRISPR-Cas9-patent-dispute-A-10-year-timeline-of-fundamental-scientific_fig1_364149815\" target=\"_blank\">there is a huge dispute\u003C\u002Fa> about the whole issue \u003Ca href=\"https:\u002F\u002Fipwatchdog.com\u002F2024\u002F05\u002F06\u002Fcrispr-battle-lens-international-patent-harmonization\u002Fid=176202\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">for over a decade\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>Katrine Bosley, CEO of Editas Medicine said that because CRISPR can “repair broken genes” it holds promise for treating several thousand inherited disorders caused by gene mistakes, most of which, like Huntington’s disease and cystic fibrosis, have no cure. In 2015, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.technologyreview.com\u002Fs\u002F543181\u002Fcrispr-gene-editing-to-be-tested-on-people-by-2017-says-editas\u002F\" target=\"_blank\">the company announced that\u003C\u002Fa> it was planning a clinical trial in 2017 using CRISPR gene editing techniques to treat Leber’s congenital amaurosis, a rare genetic illness that causes blindness. Although the company announced \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fir.editasmedicine.com\u002Fnews-releases\u002Fnews-release-details\u002Feditas-medicine-announces-clinical-data-demonstrating-proof\" target=\"_blank\">favorable progress\u003C\u002Fa>, this project is not listed \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.editasmedicine.com\u002Fgene-editing-pipeline\u002F\" target=\"_blank\">in their pipeline\u003C\u002Fa>. According to that, their most advanced project is a treatment for Sickle cell disease in late-stage clinical trials.  \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"580\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcrispr-therapeutics.jpg\" alt=\"CRISPR Therapeutics\" class=\"wp-image-15724\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcrispr-therapeutics.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcrispr-therapeutics-768x512.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcrispr-therapeutics-512x341.jpg 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F05\u002Fcrispr-therapeutics-375x250.jpg 375w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Genomics is a huge field that advances fast. The real questions will not be whether we can sequence genomes basically for free or whether we can edit diseases „out” but how we will deal with such profound ethical questions as the \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhat-could-crisprcas9-do-tomorrow\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">one around designer babies\u003C\u002Fa> and affecting evolution on the long term.\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",{"rendered":1005,"protected":16},"\u003Cp>From portable genome sequencers until genetic tests revealing distant relations with Thomas Jefferson, genomics represents a fascinatingly innovative area of healthcare. As the price of genome sequencing has been in free fall for years, the start-up scene is bursting from transformative power. Let’s look at some of the most amazing genomics companies!\u003C\u002Fp>\n",22433,{"_acf_changed":16,"footnotes":64},[5,442],[80,82,1010,700,1011,1012,1013,864,1014,75,1015,1016,1017,1018],522,608,144,655,694,695,213,696,218,[],[],[109,1022,1023,1024,1025,1026,1027,1028,1029,106,1030,1031,1032,1033,1034,1035,1036],3033,1981,3035,2035,3043,2045,3561,2657,2935,3019,3023,3025,3029,1727,3031,[1038,53,116,117,118,119,120,123,462,133,135,1039,729,1040,1041,1042,903,1043,128,1044,1045,1046,1047],"post-15713","tag-gc3","tag-precision-medicine","tag-artificial-intelligence","tag-genome-sequencing","tag-personal-genomics","tag-bioinformatics","tag-dna-testing","tag-genetic-disorders","tag-dtc",{"id":1006,"alt_text":1049,"caption":64,"description":1050,"media_type":149,"media_details":1051,"post":1073,"source_url":1074},"TMF, pharmacogenomics","TMF, pharmacogenomics, drug, dna, personalized medicine, man",{"width":598,"height":442,"file":1052,"sizes":1053,"image_meta":1071},"2018\u002F11\u002F053-pharmacogenomics.png",{"medium":1054,"large":1057,"thumbnail":1060,"medium_large":1063,"large_old_512x288":1064,"thumbnail_old_150x150":1067,"medium_old_370x208":1068,"medium_large_old_768x432":1069,"large_old_512x288_old_512x288":1070},{"file":1055,"width":157,"height":158,"mime-type":338,"source_url":1056},"053-pharmacogenomics-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F053-pharmacogenomics-370x208.png",{"file":1058,"width":163,"height":164,"mime-type":338,"source_url":1059},"053-pharmacogenomics-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F053-pharmacogenomics-768x432.png",{"file":1061,"width":168,"height":168,"mime-type":338,"source_url":1062},"053-pharmacogenomics-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F053-pharmacogenomics-150x150.png",{"file":1058,"width":163,"height":164,"mime-type":338,"source_url":1059},{"file":1065,"width":173,"height":174,"mime-type":338,"source_url":1066},"053-pharmacogenomics-512x288.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F053-pharmacogenomics-512x288.png",{"file":1061,"width":177,"height":177,"mime-type":338,"source_url":1062},{"file":1055,"width":179,"height":180,"mime-type":338,"source_url":1056},{"file":1058,"width":182,"height":183,"mime-type":338,"source_url":1059},{"file":1065,"width":185,"height":186,"mime-type":338,"source_url":1066},{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188,"keywords":1072},[],22423,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F053-pharmacogenomics.png",{"related_posts":16,"related_posts_footer":1076,"cta_type":364,"cta_color":64,"subtitle":64,"related_books":1078,"key_takeaways":1080},[422,620,1077],17884,[367,1079,939],24761,[1081,1083,1085],{"title":1082},"\u003Cp>This is a cutting-edge field where groundbreaking announcements happen daily, often blurring the lines between reality and sci-fi utopias.\u003C\u002Fp>\n",{"title":1084},"\u003Cp>I’ve examined this segment and picked the key players who have truly made significant contributions in recent years.\u003C\u002Fp>\n",{"title":1086},"\u003Cp>Here are the leading companies across seven segments, from personal genomics to precision oncology and CRISPR.\u003C\u002Fp>\n",{"yoast_wpseo_title":1088,"yoast_wpseo_metadesc":1089,"yoast_wpseo_canonical":999},"Top 23 Companies in Genomics & Genetics - The Medical Futurist","Top 23 Genomics Companies in Personal genomics, Pharmacogenomics, Genetic ancestry, CRISPR: ✅23andme ✅Futura Genetics ✅Veritas Genetics",{"self":1091,"collection":1096,"about":1098,"author":1100,"replies":1102,"version-history":1105,"predecessor-version":1108,"wp:featuredmedia":1112,"wp:attachment":1115,"wp:term":1118,"curies":1129},[1092],{"href":1093,"targetHints":1094},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15713",{"allow":1095},[27],[1097],{"href":220},[1099],{"href":223},[1101],{"embeddable":41,"href":226},[1103],{"embeddable":41,"href":1104},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=15713",[1106],{"count":396,"href":1107},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15713\u002Frevisions",[1109],{"id":1110,"href":1111},57835,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15713\u002Frevisions\u002F57835",[1113],{"embeddable":41,"href":1114},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F22433",[1116],{"href":1117},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=15713",[1119,1121,1123,1125,1127],{"taxonomy":11,"embeddable":41,"href":1120},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=15713",{"taxonomy":248,"embeddable":41,"href":1122},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=15713",{"taxonomy":251,"embeddable":41,"href":1124},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=15713",{"taxonomy":254,"embeddable":41,"href":1126},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=15713",{"taxonomy":257,"embeddable":41,"href":1128},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=15713",[1130],{"name":39,"href":40,"templated":41},{"id":620,"date":1132,"date_gmt":1133,"guid":1134,"modified":1136,"modified_gmt":1137,"slug":1138,"status":52,"type":53,"link":1139,"title":1140,"content":1142,"excerpt":1144,"author":61,"featured_media":578,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1146,"categories":1147,"tags":1148,"project_category":1157,"contact_email_category":1158,"yst_prominent_words":1159,"class_list":1176,"better_featured_image":1186,"acf":1200,"yoast_meta":1210,"_links":1212},"2024-07-29T13:54:53","2024-07-29T11:54:53",{"rendered":1135},"https:\u002F\u002Fmedicalfuturist.com\u002F","2024-07-29T12:58:29","2024-07-29T10:58:29","i-got-my-whole-genome-sequenced-heres-what-i-learned","https:\u002F\u002Fmedicalfuturist.com\u002Fi-got-my-whole-genome-sequenced-heres-what-i-learned",{"rendered":1141},"I Got My Whole Genome Sequenced. Here’s What I Learned.",{"rendered":1143,"protected":16},"\n\u003Cp class=\"has-text-align-left\">Dante Labs sent me their Full DNA whole genome sequencing package, and I went through a roller-coaster of feelings: I was excited to know every secret of my DNA, but I was afraid of getting to know my hereditary cancer risks and worried what else I might find. As in my case, (scientific) curiosity usually overrides fear, I jumped into the unknown and I’m eager to share my results here.\u003C\u002Fp>\n\n\n\u003Cp>\u003Ciframe loading=\"lazy\" title=\"What happens when I get my genome sequenced - The Medical Futurist\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FRrTzi6C05lw?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003C\u002Fp>\n\n\n\n\u003C!--more-->\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Whole genome sequencing is available to anyone. So what?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp class=\"has-text-align-left\">The human genome is the blueprint for building a person. When the \u003Ca href=\"https:\u002F\u002Fwww.genome.gov\u002F12011238\u002Fan-overview-of-the-human-genome-project\u002F\">Human Genome Project\u003C\u002Fa> was completed in 2006, and the DNA double spiral uncovered its secrets for the very first time, scientists agreed that it’s just as a revolutionary moment for mankind as Neil Armstrong stepping on the Moon. \u003Ca href=\"https:\u002F\u002Fghr.nlm.nih.gov\u002Fprimer\u002Fhgp\u002Fdescription\">Researchers said\u003C\u002Fa> that learning about the functions of genes and proteins will have a major impact in the fields of medicine, biotechnology, and life sciences.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Although \u003Cstrong>the technical conditions, \u003C\u002Fstrong>\u003Cstrong>\u003Ca href=\"https:\u002F\u002Fpdfs.semanticscholar.org\u002F0e38\u002F7bd00952c8450deefcdbcdebf5c946c20f54.pdf\">the time and the cost of sequencing genomes were reduced by a factor of 1 million in less than 10 years\u003C\u002Fa>\u003C\u002Fstrong>\u003Cstrong>, the revolution lags behind. Before you start worrying, I can assure you: it will come\u003C\u002Fstrong>. When the price of genome sequencing reaches that of a blood test – it is already dropping below $1000 – and the data analysis will happen according to layers (and special pricing according to the various batches of information!), we will see how many areas of our lives genetic information impacts. \u003Cstrong>It affects pharmaceutical decisions, lifestyle and dietary choices, disease prevention plans, the human aging process and life expectancy in general.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">However, the latter has been questioned over time for the advantage of environmental factors. In the 1990s, scientists estimated that genetics has a 20 percent say in the human life expectancy, however, it was already \u003Ca href=\"https:\u002F\u002Fghr.nlm.nih.gov\u002Fprimer\u002Fhgp\u002Fdescription\">reduced to 15 percent in a study conducted in 2011\u003C\u002Fa>, while \u003Ca href=\"http:\u002F\u002Fscience.sciencemag.org\u002Fcontent\u002F360\u002F6385\u002F171\">a research published this year also concluded\u003C\u002Fa> that human relationships and the environment, in general, have an overwhelmingly more dominant effect on the lifespan of individuals than genetic inheritance.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Still, bearing all the limitations in mind, I was absolutely over the Moon that \u003Ca href=\"https:\u002F\u002Fwww.dantelabs.com\">Dante Labs\u003C\u002Fa> sent me their \u003Ca href=\"https:\u002F\u002Fwww.dantelabs.com\u002Fproducts\u002Fwhole-genome-sequencing\">Full DNA whole genome sequencing package\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone wp-image-22361 size-full\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"585\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FGenetic-Testing.jpg\" alt=\"\" class=\"wp-image-22361\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FGenetic-Testing.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FGenetic-Testing-768x516.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FGenetic-Testing-512x344.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.fortune.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Expectations as high as the Mount Everest\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp class=\"has-text-align-left\">Over the years, I have already gathered a lot of experience regarding genetic testing – with Navigenics, Pathway Genomics, My Gentle Labs, Futura Genetics, just to name a few. I have learned what medication would have a side effect on me; what major conditions I’m at risk for; why I have certain features such as the inability to run marathons and what I can expect from the future. Our team even reviewed \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fhow-does-a-brca-genetic-test-work\">the BRCA test produced by Dante Labs\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">However, the difference between genetic tests and whole genome sequencing is like that of a seat on the bus or having your own car. With the first, your route is kinda determined and you only have one seat – it’s partial. With a car, you have infinite chances where to go and you own the entire vehicle. The majority of direct-to-consumer genetic tests determine various single nucleotide polymorphisms (or SNPs). These can \u003Ca href=\"https:\u002F\u002Fghr.nlm.nih.gov\u002Fprimer\u002Fgenomicresearch\u002Fsnp\">act as biological markers, helping scientists locate genes that are associated with a disease.\u003C\u002Fa> When SNPs occur within a gene or in a regulatory region near a gene, they may play a more direct role in disease by affecting the gene’s function. In the end, however, SNPs are only indicators of health risks, and a great deal of information remains hidden in the genome.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Thus, I expected that Dante Labs, which is working with leading genetic labs in the United States, Europe, and Asia; and partnered with Harvard University, Amazon, the Global Alliance for Genomics & Health or Privacy Shield Framework, will offer me \u003Cstrong>a crystal-clear overview of my chances for a healthy life. I wished to see what conditions I could prevent, what medications I should avoid – and what does my body carry in general. \u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003Cstrong>As the DNA package contains a hereditary cancer report with risks, e.g. for \u003C\u002Fstrong>\u003Cstrong>\u003Ca href=\"https:\u002F\u002Fwww.dantelabs.com\u002Fproducts\u002Fwhole-genome-sequencing\">colorectal or prostate cancer\u003C\u002Fa>\u003C\u002Fstrong>\u003Cstrong>, I was nervous for weeks what they might find\u003C\u002Fstrong>. However, I do believe that \u003Ca href=\"https:\u002F\u002Fwww.dantelabs.com\u002Fproducts\u002Fwhole-genome-sequencing\">you have to think proactively and that it’s better to know the risks\u003C\u002Fa> and to ensure preventive measures than bury your head in the sand, so after a while I let my fears go and started to become rather curious what I will know. Perhaps naively, I had the sense that I can add a significant chunk of new information to the familial health landscape – since I can uncover such genetic health risks as no one ever before.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"653\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs-Kit.jpg\" alt=\"Dante Labs DNA package\" class=\"wp-image-22397\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs-Kit.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs-Kit-768x576.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs-Kit-512x384.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>The sampling process was as familiar as stampedes around Black Friday\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp class=\"has-text-align-left\">There is a commonly known sampling process when it comes to genetic tests, and it is almost the same in the case of the Dante Labs whole genome sequencing package. Same old, same old. Just as you would expect crazy crowds on Black Friday in shopping malls, you can prepare for a saliva test here.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">You cannot eat, drink, smoke or chew gum for half an hour before you do the sampling, and then you are instructed to give some saliva into a tube. You screw on the cap, which will release the DNA preserving liquid, you mix the materials and then seal the container. As it is a biological sample, you have some administrative work to do, but there was truly no difference compared to other tests. Actually, the process is so standardized by now that you can \u003Ca href=\"https:\u002F\u002Fwww.dnagenotek.com\u002FROW\u002Fproducts\u002Fcollection-human\u002Foragene-dna\u002F500-series\u002FOG-500.html\">buy a kit online to collect “superior samples” at home\u003C\u002Fa>. Oh, capitalism, you have an investor for everything.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"Taking a Dante Labs Full DNA Test - The Medical Futurist\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FrP42QBhgmHo?start=18&feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>The waiting period was as nerve-racking as filling the time until the final season of GoT\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp class=\"has-text-align-left\">Two months. Eight weeks to be precise. That’s \u003Ca href=\"https:\u002F\u002Fwww.pedigree.com\u002Fdog-care\u002Fdog-age-calculator\">two years for an Anatolian shepherd dog\u003C\u002Fa>! \u003Ca href=\"https:\u002F\u002Ffromtone.com\u002Fchinas-ghost-cities\u002F\">China is even building cities in the size of Rome\u003C\u002Fa> every two months for the last decade… so while I had to wait for the results, Chinese construction workers established a new (ghost) city somewhere in the mainland. Nevertheless, the situation was not that miserable, as I could follow it on the online platform whether my sample arrived, where the processing stands and what I could expect.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Thus, I waited. As you could imagine, that’s NOT among my favorite activities. What could I do to pass the time? I went to my primary care physician to tell her that I expect such a sample (side note: she hasn’t gone through the results yet, I’ll let you know as soon as she does so) and asked her to help me in interpreting the results. Besides, I also checked what kind of reports they will send me. I was expecting a thorough \u003Ca href=\"https:\u002F\u002Fwww.dantelabs.com\u002Fproducts\u002Fwhole-genome-sequencing\">health and wellness report and an overview of my risks regarding genetic diseases\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22364\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"532\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDNA-Sequencing.jpg\" alt=\"whole genome sequencing\" class=\"wp-image-22364\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDNA-Sequencing.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDNA-Sequencing-768x470.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDNA-Sequencing-512x313.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.dnatestingchoice.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Joy and happiness: the results arrived!\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp class=\"has-text-align-left\">Finally, \u003Cstrong>my report of altogether 163 pages and my raw data was available. Dante Labs sequenced all the 3,095,677,412 base pairs that I possess and gave me a thorough overview of myself. That’s fascinating and weird at the same time.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">At first, I was baffled by the size of the document and I was afraid that I’ll have \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fhow-to-overcome-being-cyberchondriac\">cyberchondriac\u003C\u002Fa> tendencies. However, the report supports interpretation with several “crutches”: they emphasize the likelihood of the risks, they include various illustrations and scales to visualize the results, and they also divide the outcome based on the prevalence of evidence. Thus, there is a difference between having a risk based on one study or fifty – more evidence certainly gives more weight to a risk and it helps the tester to put the results into perspective.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Bearing these in mind, I went through the report. Although I already knew some of the results from previous genetic tests, the majority of the findings was entirely new for me, and I understood a lot more about myself. In some instances, I even found the explanation for my inclination towards activities. For example, I read sentences like your genes indicate you are likely to excel at power-based sports and training, but less likely to be good at endurance sporting activities. For all my life, I have been aware of the fact that I’m not a long-distance runner, but now also understand why I had the tendency to choose sprints and why I’m better at running fast for short distances. Nevertheless, on the same page, I was also glad to read that I don’t have sickle cell trait or that I’m not predisposed to an abnormal amount of exercise-induced fatigue.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">I was also informed that I have a moderate risk for melanoma, which I already knew from previous genetic tests. They informed me that tanning beds or sunburns are highly avoidable for me – although I did that pretty much for my entire life. Another previously known fact about myself was my predisposition to thrombosis. They detailed that I have a Factor V Leiden mutation and a Factor V R2 mutation. The report said that means I have a slightly elevated risk for abnormal blood clots forming in my veins.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"331\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FWhole-Genome-Sequencing-Test-Results.png\" alt=\"whole genome sequencing\" class=\"wp-image-22362\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FWhole-Genome-Sequencing-Test-Results.png 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FWhole-Genome-Sequencing-Test-Results-768x292.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FWhole-Genome-Sequencing-Test-Results-512x195.png 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Pharmacogenomic findings and the need for advice\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp class=\"has-text-align-left\">The report had a special section devoted to \u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC2014592\u002F\">pharmacogenomics\u003C\u002Fa>, which deals with the variability in drug response due to the genetic code. It argues that despite general sentiments, medications do not have the same effect on people. Some doctors already highly \u003Ca href=\"https:\u002F\u002Fwww.pharmgkb.org\u002Fguideline\u002FPA166104949\">recommend genetic testing before any prescription of, e.g.\u003C\u002Fa> Warfarin, a type of anti-blood clotting drug takes place. Dante Labs also tests for Warfarin, and it turned out I have a slight resistance towards that.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Nevertheless, I received information about how my body metabolizes more than a hundred drugs, which is incredibly useful. For example, my cholesterol level is usually higher than the reference value, however, I would definitely have severe side effects if I took prescription pills for high levels of cholesterol. That means a risk for cardiomyopathy, for example. Moreover, the test revealed that I have a risk to develop lactose intolerance as an adult – and I already suspected that, and now the report confirmed it.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">However, I had no idea before that I have a high risk for knee arthritis and moderate ones for hip and wrist arthritis, so I should rather not gain weight during the years and I should not wear high heels quite often. That latter came as a real shocker. But jokes aside, I’m glad that I know about these risks alongside with the risk for atrial fibrillation, cardiovascular disease, colorectal cancer or brain aneurysm.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003Cstrong>All-in-all, I was very curious and fascinated to read the overview. I also thought that as a geneticist, I will not have any problem even with the most stringent medical explanation. However, when I went through the entire report, I had to face the truth: I need a genetic counselor to make the right conclusions\u003C\u002Fstrong>. So I turned to Dante Labs and my primary care physician.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"567\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FPharmacogenomic-results.png\" alt=\"whole genome sequencing\" class=\"wp-image-22399\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FPharmacogenomic-results.png 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FPharmacogenomic-results-768x500.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FPharmacogenomic-results-512x334.png 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Pieces of advice from a genetic counselor\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp class=\"has-text-align-left\">In the quest to understand my genetic code, I asked Dante Labs whether they have a genetic counselor. It turned out they cooperate with the \u003Ca href=\"https:\u002F\u002Fwww.dnafeed.com\u002F\">DNAfeed.com\u003C\u002Fa> team, but they don’t have an advisor on their own. When you go to the site, you provide your e-mail address and upload the raw data, then a smart algorithm analyzes it and compares it to the latest scientific findings, and in the end, you have the chance to talk your results through with a specialist.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003Cstrong>I had \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-genomic-data-challenges-of-the-future\">many privacy concerns about whether or not I should share my genomic information\u003C\u002Fa>\u003C\u002Fstrong>\u003Cstrong> with the team. I started to do my research, and it turned out that the service is HIPAA-compliant, information sharing is protected and encrypted, so I took a deep breath and uploaded my sample\u003C\u002Fstrong>. And then I asked. Tons of questions.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">I was curious whether I had any significant risk that I should definitely be aware of and take into consideration when making lifestyle choices. I wanted to know whether I had certain risks against which I could individually act or whether I possess a genetic factor that I should always keep in the back of my mind.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">The clinician calmed me by saying I don’t have any mutations in any of the known genes that may substantially increase my risk of hereditary cancer, for example, BRCA. The counselor mentioned the slightly increased risks for melanoma and colorectal cancer, but also explained the steps to take to prevent them: proper skin protection from sun exposure and consider periodic skin checks with a doctor; getting the recommended screening with colonoscopies to catch any potential tumors early.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Moreover, the physician explained that I have a Factor V Leiden mutation, which is a specific gene mutation that results in thrombophilia. That gives me a slightly increased tendency to form abnormal blood clots that can block blood vessels. Nevertheless, he also added the much-needed context: this is a common mutation that 3-8% of people may have, and most people with this mutation never develop clots.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">That’s the primary reason why I decided for genetic counseling. You need to hear from a clinician that if you have a gene mutation or SNP, how likely it is going to cause you any problems later on and how likely its prevalence is in the population. In the case of thrombosis risk, I will also do everything to avoid it: I do what it takes not to gain weight and I regularly do sports.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22367\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"580\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FGenetic-Testing-Counseling.jpg\" alt=\"whole genome sequencing\" class=\"wp-image-22367\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FGenetic-Testing-Counseling.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FGenetic-Testing-Counseling-768x512.jpg 768w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.healthblog.uofmhealth.org\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>The digital afterlife of my DNA data\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp class=\"has-text-align-left\">I am content that all \u003Cstrong>these pieces of valuable information are available for me – and my future self. However, the data set is also at the disposal of the company – and many people are afraid to have a genomic test mainly due to concerns of misuse of personal data. So I asked Dante Labs what happens with my sample and DNA after the testing procedure\u003C\u002Fstrong>. They told me they discard the saliva samples after the delivery of the results. However, customers can ask the enterprise to keep the DNA if they wish to do that.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Dante Labs stores the genetic reports in their database so that customers can always have access to them. On the other hand, they don’t share data with friends, family, healthcare professionals or other individuals – that’s up to the customers.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">As the majority of genetic testing companies, Dante Labs also asks everyone whether they consent to the use of data for scientific research. Recently, it turned out that \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-genomic-data-challenges-of-the-future\">pharma companies invest heavily in direct-to-consumer genetic testing firms\u003C\u002Fa>, thus I inquired about the nature of research done by Dante Labs. They told me that they run internal research for advancing science in the field of precision medicine. However, if the customer wants to opt-out, there’s an option for that, too.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22368\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"455\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDNA-Sample.png\" alt=\"whole genome sequencing\" class=\"wp-image-22368\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDNA-Sample.png 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDNA-Sample-768x402.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDNA-Sample-512x268.png 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Source: www.futurism.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Cp class=\"has-text-align-left\">For me, the whole genome sequencing report turned out to be liberating on the one hand and gave me much to process on the other side. After I learned all the risks that my body carries for the future, I went to my primary care physician to discuss how I’m going to fight the battles with my genes. As she has my entire medical history, she is the most appropriate medical professional to discuss the way forward for me. She suggested yearly dermatological exams, and she also drew my attention to the fact that if I ever have to go to the hospital and lay in bed for 1-2 days, I have to receive anticoagulants. As she was also concerned about the colorectal cancer risk, she promised me to go after more relevant studies and will get back to me soon.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">While the information encoded in our DNA is unalterable (\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhat-could-crisprcas9-do-tomorrow\">for the moment, at least\u003C\u002Fa>), the environmental factors depend pretty much on us, humans. And as scientific research proved, that has a lot more impact on a person’s life expectancy, for example, than genetics.\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">Thus, as a next step, I will pack up my health sensors and trackers, go to the specialists and make a plan on how to avoid my genetic risks. Fortunately, I’m not alone in my fight – and you are also aided. By technology and great medical professionals. That’s why I advise you to have your whole genome sequenced. I already ordered two further kits – one for my wife and one for my daughter, Mira, too. So, you can prepare for your own future in time – to get from chance to choice.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>A 2024 update\u003C\u002Fstrong>: Since this article, I’ve received a lot of e-mails and comments from other users of this service complaining about customer service and how much they had to wait for their results. I didn’t have the same experience but I wanted to mention it to provide an objective review.\u003C\u002Fp>\n\n\n\n\u003Cp>Here are the pros & cons of  Dante Labs’ Full DNA Whole Genome Sequencing:  \u003C\u002Fp>\n\n\n\u003Cdiv class=\"wp-block-image\">\n\u003Cfigure class=\"alignleft\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"870\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs_Whole-Genome-Sequencing.png\" alt=\" Dante Labs Full DNA Whole Genome Sequencing\" class=\"wp-image-22405\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs_Whole-Genome-Sequencing.png 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs_Whole-Genome-Sequencing-768x768.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs_Whole-Genome-Sequencing-150x150.png 150w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDante-Labs_Whole-Genome-Sequencing-512x512.png 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\u003C\u002Fdiv>\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",{"rendered":1145,"protected":16},"\u003Cp>Dante Labs sent me their Full DNA whole genome sequencing package, and I went through a roller-coaster of feelings: I was excited to know every secret of my DNA, but I was afraid of getting to know my hereditary cancer risks and worried what else I might find. As in my case, (scientific) curiosity usually overrides fear, I jumped into the unknown and I’m eager to share my results here.\u003C\u002Fp>\n",{"_acf_changed":16,"footnotes":64},[280,5,442],[72,1013,75,90,78,1149,1150,91,704,1151,84,1152,1153,859,1154,1155,1156],1102,271,1135,1136,373,382,1138,1139,[],[],[1160,109,1161,1023,1162,1163,1164,1025,1165,1166,1167,1168,1169,1170,1171,1172,1173,1027,1174,1175],2049,2051,2053,2033,2055,2057,2037,2059,2039,2061,2041,2063,2043,2065,2067,2047,[1177,53,116,117,118,119,120,314,123,462,125,1042,128,143,131,1178,1179,144,733,1180,137,1181,1182,898,1183,1184,1185],"post-22360","tag-genomic-data","tag-health","tag-whole-genome-sequencing","tag-genomic-testing","tag-research","tag-science","tag-health-risks","tag-health-science",{"id":578,"alt_text":596,"caption":64,"description":64,"media_type":149,"media_details":1187,"post":620,"source_url":17},{"width":598,"height":442,"file":599,"sizes":1188,"image_meta":1198},{"medium":1189,"large":1190,"thumbnail":1191,"medium_large":1192,"large_old_512x288":1193,"thumbnail_old_150x150":1194,"medium_old_370x208":1195,"medium_large_old_768x432":1196,"large_old_512x288_old_512x288":1197},{"file":602,"width":157,"height":158,"mime-type":338,"source_url":603},{"file":605,"width":163,"height":164,"mime-type":338,"source_url":606},{"file":608,"width":168,"height":168,"mime-type":338,"source_url":609},{"file":605,"width":163,"height":164,"mime-type":338,"source_url":606},{"file":612,"width":173,"height":174,"mime-type":338,"source_url":613},{"file":608,"width":177,"height":177,"mime-type":338,"source_url":609},{"file":602,"width":179,"height":180,"mime-type":338,"source_url":603},{"file":605,"width":182,"height":183,"mime-type":338,"source_url":606},{"file":612,"width":185,"height":186,"mime-type":338,"source_url":613},{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188,"keywords":1199},[],{"related_posts":16,"related_posts_footer":1201,"cta_type":64,"cta_color":64,"subtitle":64,"related_books":16,"key_takeaways":1205},[1202,1203,1204],22156,14029,17644,[1206,1208],{"title":1207},"\u003Cp>I got my genome sequences back in 2018 to learn about disease risks, medication sensitivities and maybe even more.\u003C\u002Fp>\n",{"title":1209},"\u003Cp>Working with a genetic counselor, I could access a lot of data and draw meaningful conclusions from that to improve my lifestyle and health managemenet with the supervision of my primary care physician.\u003C\u002Fp>\n",{"yoast_wpseo_title":1141,"yoast_wpseo_metadesc":1211,"yoast_wpseo_canonical":1139},"Dante Labs sent me their Full DNA whole genome sequencing package. Here's everything I learned from my whole genome sequencing report.",{"self":1213,"collection":1218,"about":1220,"author":1222,"replies":1224,"version-history":1227,"predecessor-version":1231,"wp:featuredmedia":1235,"wp:attachment":1237,"wp:term":1240,"curies":1251},[1214],{"href":1215,"targetHints":1216},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F22360",{"allow":1217},[27],[1219],{"href":220},[1221],{"href":223},[1223],{"embeddable":41,"href":226},[1225],{"embeddable":41,"href":1226},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=22360",[1228],{"count":1229,"href":1230},23,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F22360\u002Frevisions",[1232],{"id":1233,"href":1234},57261,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F22360\u002Frevisions\u002F57261",[1236],{"embeddable":41,"href":654},[1238],{"href":1239},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=22360",[1241,1243,1245,1247,1249],{"taxonomy":11,"embeddable":41,"href":1242},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=22360",{"taxonomy":248,"embeddable":41,"href":1244},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=22360",{"taxonomy":251,"embeddable":41,"href":1246},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=22360",{"taxonomy":254,"embeddable":41,"href":1248},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=22360",{"taxonomy":257,"embeddable":41,"href":1250},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=22360",[1252],{"name":39,"href":40,"templated":41},{"id":1254,"date":1255,"date_gmt":1256,"guid":1257,"modified":1259,"modified_gmt":1260,"slug":1261,"status":52,"type":53,"link":1262,"title":1263,"content":1265,"excerpt":1267,"author":61,"featured_media":1269,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1270,"categories":1271,"tags":1272,"project_category":1279,"contact_email_category":1280,"yst_prominent_words":1281,"class_list":1284,"better_featured_image":1292,"acf":1315,"yoast_meta":1328,"_links":1331},56163,"2024-05-23T09:30:00","2024-05-23T07:30:00",{"rendered":1258},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=56163&_wpnonce=d85dc5f64a&status=auto-draft&type=post","2024-05-23T08:08:27","2024-05-23T06:08:27","the-promise-of-crispr-gpt-specialized-chatgpts-could-transform-medicine","https:\u002F\u002Fmedicalfuturist.com\u002Fthe-promise-of-crispr-gpt-specialized-chatgpts-could-transform-medicine",{"rendered":1264},"The Promise Of CRISPR GPT: Specialised ChatGPTs Could Transform Medicine",{"rendered":1266,"protected":16},"\n\u003Cp>We’ve recently \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fd41586-024-01243-w\" target=\"_blank\">come across\u003C\u002Fa> some \u003Ca href=\"https:\u002F\u002Farxiv.org\u002Fpdf\u002F2404.18021\">fascinating\u003C\u002Fa> developments in the field of gene editing: CRISPR GPT, a large language model agent designed to automate the design of gene-editing experiments. This got us thinking: what other ‘\u003Cem>specialty GPTs\u003C\u002Fem>‘ could we think of? What highly specific applications might there be for large language models (LLMs)?\u003C\u002Fp>\n\n\n\n\u003Cp>CRISPR GPT is a large language model similar to ChatGPT, but it’s been trained on a very specialised dataset focused on gene editing and CRISPR technology. This makes it exceptionally effective in that specific area, understanding the nuances of gene editing, identifying potential errors or risks, and suggesting optimal experimental designs. However, unlike ChatGPT, which is designed to handle a broad range of general questions, CRISPR GPT may not perform well on general queries outside its gene-editing domain. \u003C\u002Fp>\n\n\n\n\u003Cp>The genius of this idea is using a large language model’s ability to handle vast amounts of data in gene editing. Researchers must sift through massive databases to identify suitable gene sequences, understand potential side effects, and optimise the CRISPR system. An LLM like GPT can analyse this data, identify patterns, and make suggestions, significantly accelerating and enhancing the research process.\u003C\u002Fp>\n\n\n\n\u003Cp>So, what other fields could benefit from this technology? Where else in medicine do professionals need to interact with, analyse, and interpret enormous amounts of complex data?\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">At pharmaceutical companies\u003C\u002Fh2>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for drug discovery\u003C\u002Fh3>\n\n\n\n\u003Cp>Drug-GPTs could quickly go through massive datasets of molecular structures, chemical properties, and biological activity to predict how different molecules might interact with potential drug targets. This could significantly speed up identifying promising drug candidates and optimising their structures, accelerating the development of new medications.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for protein engineering\u003C\u002Fh3>\n\n\n\n\u003Cp>Protein engineering is another field ripe for innovation with GPT. These models can assist in developing new proteins with specific functions, which are crucial in biotechnology and therapeutic applications. By simulating protein folding and interactions, GPT can help design proteins that perform desired tasks, potentially leading to breakthroughs in medical treatments and industrial processes.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F11\u002Ftmf_article_299-01-768x432.png\" alt=\"drug, drug design, pharma\" class=\"wp-image-36791\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F11\u002Ftmf_article_299-01-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F11\u002Ftmf_article_299-01-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F11\u002Ftmf_article_299-01-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F11\u002Ftmf_article_299-01.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for antibody design\u003C\u002Fh3>\n\n\n\n\u003Cp>Antibody-GPTs could generate novel antibody sequences for therapeutic use, enhancing the immune response or targeting specific pathogens with high precision. This capability could lead to the rapid development of new treatments for various infectious and autoimmune diseases.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for clinical trial design\u003C\u002Fh3>\n\n\n\n\u003Cp>Trial-GPT can streamline the design of clinical trials by analysing biomedical literature and patient data to identify optimal trial designs, patient cohorts, and potential biomarkers. Which means faster development of new treatments and improved efficiency of clinical research.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">In medical practices and hospitals\u003C\u002Fh2>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for personalised medicine\u003C\u002Fh3>\n\n\n\n\u003Cp>Doctor-GPTs digest patient data in seconds, including genetic information, medical history, lifestyle factors, and environmental exposures. This can help identify individual risk factors, predict disease susceptibility, and tailor treatment plans to each patient’s unique genetic makeup. With such a personalised approach, patients could receive the most effective therapies based on their genetic and health profiles. Thinking a bit ahead, such LLMs could help us move medicine towards prevention, instead of treatments.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for 3D printing in medicine\u003C\u002Fh3>\n\n\n\n\u003Cp>Special 3D-printing LLMs could help design intricate scaffolds for tissue engineering, optimize printing parameters for different materials, and even predict how printed structures will interact with biological tissues. This could lead to more precise and personalised medical devices and potentially even accelerate the development of bioprinted organs for transplantation.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01-768x432.png\" alt=\"3D printing\" class=\"wp-image-33403\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for cancer genomics\u003C\u002Fh3>\n\n\n\n\u003Cp>A Cancer-GPT could analyse large-scale genomic data from cancer patients to identify the specific mutations driving tumor growth and predict how tumors will respond to different treatments. This could lead to more targeted therapies and improve the chances of successful treatment for cancer patients.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for surgical planning\u003C\u002Fh3>\n\n\n\n\u003Cp>Surgeon-GPTs could assist surgical planning for complex procedures. They could analyse patient data and medical imaging, simulate different surgical approaches, determine the best strategies, minimize risks, and improve patient outcomes.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">For everyone\u003C\u002Fh2>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for neural network simulations\u003C\u002Fh3>\n\n\n\n\u003Cp>LLMs could be used to create detailed simulations of neural circuits, helping researchers understand how neurons communicate, how neural networks process information, and how different brain regions interact. These simulations could also help identify how disruptions in neural circuits lead to neurological disorders like Alzheimer’s, Parkinson’s, and epilepsy. Ultimately, this could lead to new treatments for these debilitating conditions.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for nutritional science\u003C\u002Fh3>\n\n\n\n\u003Cp>A Nutrition-GPT could assist in nutritional science by analysing dietary data, medical history, and genetic information to create personalised nutrition plans. This can help individuals achieve better health outcomes through tailored dietary recommendations based on their specific needs and conditions. What \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhy-is-nutrigenomics-the-biggest-flop-in-digital-health\u002F\">nutrigenomics\u003C\u002Fa> currently lacks to deliver on its promises could maybe come from large language models. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-768x432.png\" alt=\"nutrigenomics\" class=\"wp-image-48473\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-2048x1152.png 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">GPT for epidemiology\u003C\u002Fh3>\n\n\n\n\u003Cp>The Covid-pandemic was \u003Ca href=\"https:\u002F\u002Fdeptmedicine.utoronto.ca\u002Fnews\u002Ftracking-coronavirus-pandemic-ai-bluedot-featured-60-minutes\">first spotted by Bluedot\u003C\u002Fa>, an AI company in Toronto. As the AI arena just got more advanced in the past few years, the field of epidemiology can handsomely benefit from its development. Pandemic-GPT could analyse data from various sources to predict disease outbreaks, track the spread of infectious diseases, and evaluate the effectiveness of public health interventions. This can help public health officials make informed decisions and implement timely measures to control epidemics.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Specialised GPTs are easier to image than to create\u003C\u002Fh2>\n\n\n\n\u003Cp>These are just a few examples of the many ways in which large language models could help medicine. Of course, imagining these specialised GPTs is far easier than creating them and ensuring they work reliably enough for use in healthcare. Rigorous testing, validation, and regulatory approval will be essential before these models can be deployed in real-world medical settings.\u003C\u002Fp>\n\n\n\n\u003Cp>However, thinking about potential use cases is never a waste of time. Such thought experiments highlight that there will hardly be a stone left unturned in healthcare by these changes. The new potential brought by specialised GPTs will improve the care patients can receive, enhance the work doctors can do, advance medical research, and streamline the logistics behind healthcare.\u003C\u002Fp>\n",{"rendered":1268,"protected":16},"\u003Cp>Specifically trained GPTs, like CRISPR GPT, won’t be good in general chat but will excel in analyzing DNA, designing personalized nutrition. or helping surgical planning.\u003C\u002Fp>\n",47667,{"_acf_changed":16,"footnotes":64},[440,691,5,442],[1273,446,1274,1275,1276,1277,1278],7671,7673,7741,7807,7943,7945,[710,452,871],[],[875,103,1282,1283,106],1807,3357,[1285,53,116,117,118,119,120,460,721,123,462,1286,465,1287,1288,1289,1290,1291,738,470,909],"post-56163","tag-ai-in-healthcare","tag-ai-in-medicine","tag-large-language-models","tag-gpt-in-healthcare","tag-specialzed-gpts","tag-crispr-gpt",{"id":1269,"alt_text":1293,"caption":64,"description":64,"media_type":149,"media_details":1294,"post":1313,"source_url":1314},"tmf dna sequence",{"width":1295,"height":1296,"file":1297,"sizes":1298,"image_meta":1312},1800,1012,"2022\u002F10\u002Ftmf_DNA-sequence.png",{"medium":1299,"large":1302,"thumbnail":1305,"medium_large":1308,"1536x1536":1309},{"file":1300,"width":179,"height":180,"mime-type":338,"source_url":1301},"tmf_DNA-sequence-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_DNA-sequence-370x208.png",{"file":1303,"width":182,"height":183,"mime-type":338,"source_url":1304},"tmf_DNA-sequence-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_DNA-sequence-768x432.png",{"file":1306,"width":177,"height":177,"mime-type":338,"source_url":1307},"tmf_DNA-sequence-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_DNA-sequence-150x150.png",{"file":1303,"width":182,"height":183,"mime-type":338,"source_url":1304},{"file":1310,"width":349,"height":350,"mime-type":338,"source_url":1311},"tmf_DNA-sequence-1536x864.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_DNA-sequence-1536x864.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},15142,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_DNA-sequence.png",{"cta_type":364,"cta_color":64,"related_posts_footer":1316,"related_posts":16,"related_books":1319,"subtitle":64,"key_takeaways":1321},[363,1317,1318],17898,55481,[367,1320,1079],37033,[1322,1324,1326],{"title":1323},"\u003Cp>Large language models could be surprisingly efficient in various medical areas – not just for problems including human conversations, but data and network analyses too.\u003C\u002Fp>\n",{"title":1325},"\u003Cp>Pharma companies like Roche have already started deploying their own ChatGPT-like tools in practice, there are untapped potentials in specific research areas.\u003C\u002Fp>\n",{"title":1327},"\u003Cp>As CRISPR GPT paved the way, here are a few examples that might as well become reality in the coming years.\u003C\u002Fp>\n",{"yoast_wpseo_title":1329,"yoast_wpseo_metadesc":1330,"yoast_wpseo_canonical":1262},"The Promise Of CRISPR GPT: Specialized ChatGPTs In Medicine","Specifically trained GPTs, like CRISPR GPT, won't be good in general chat but will excel in analyzing DNA or designing personalized nutrition.",{"self":1332,"collection":1337,"about":1339,"author":1341,"replies":1343,"version-history":1346,"predecessor-version":1350,"wp:featuredmedia":1354,"wp:attachment":1357,"wp:term":1360,"curies":1371},[1333],{"href":1334,"targetHints":1335},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F56163",{"allow":1336},[27],[1338],{"href":220},[1340],{"href":223},[1342],{"embeddable":41,"href":226},[1344],{"embeddable":41,"href":1345},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=56163",[1347],{"count":1348,"href":1349},7,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F56163\u002Frevisions",[1351],{"id":1352,"href":1353},56221,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F56163\u002Frevisions\u002F56221",[1355],{"embeddable":41,"href":1356},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F47667",[1358],{"href":1359},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=56163",[1361,1363,1365,1367,1369],{"taxonomy":11,"embeddable":41,"href":1362},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=56163",{"taxonomy":248,"embeddable":41,"href":1364},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=56163",{"taxonomy":251,"embeddable":41,"href":1366},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=56163",{"taxonomy":254,"embeddable":41,"href":1368},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=56163",{"taxonomy":257,"embeddable":41,"href":1370},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=56163",[1372],{"name":39,"href":40,"templated":41},{"id":1374,"date":1375,"date_gmt":1376,"guid":1377,"modified":1379,"modified_gmt":1380,"slug":1381,"status":52,"type":53,"link":1382,"title":1383,"content":1385,"excerpt":1387,"author":61,"featured_media":1389,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1390,"categories":1391,"tags":1395,"project_category":1401,"contact_email_category":1402,"yst_prominent_words":1403,"class_list":1410,"better_featured_image":1421,"acf":1442,"yoast_meta":1455,"_links":1457},32197,"2023-11-21T10:00:00","2023-11-21T09:00:00",{"rendered":1378},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=32197&_wpnonce=33632050e7&status=auto-draft&type=post","2023-11-23T11:57:25","2023-11-23T10:57:25","superhumans","https:\u002F\u002Fmedicalfuturist.com\u002Fsuperhumans",{"rendered":1384},"Will We All Have To Become Biologically Enhanced Superhumans?",{"rendered":1386,"protected":16},"\n\u003Cp>Okay, hands up who can tell who’s the most famous biologically enhanced superhuman in the world? True, it’s a quite close call between Captain America and The Incredible Hulk (sorry Spidey, you’re not even close). But are human-invented superhumans just a thing of a \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fen.wikipedia.org\u002Fwiki\u002FStan_Lee\" target=\"_blank\">Stan Lee comic\u003C\u002Fa>, or is it an actual scientific idea from a real laboratory?\u003C\u002Fp>\n\n\n\n\u003Cp>As a matter of fact, enhancing human capabilities has been on the minds of people for ages, but it has come a long way from ancient training methods to exoskeletons. Enhancing our abilities, be it permanently or temporarily is a tempting but risky matter. Will it be possible in the not-too-far future to gear up superhuman powers so we don’t lag behind the others? Let’s dive in and see how (and if) we can be our better selves.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"489\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F09\u002FSuperhero.png\" alt=\"\" class=\"wp-image-21851\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F09\u002FSuperhero.png 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F09\u002FSuperhero-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F09\u002FSuperhero-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F09\u002FSuperhero-512x288.png 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption class=\"wp-element-caption\">Superhuman – with the help of technology\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">A brief history of human enhancement\u003C\u002Fh2>\n\n\n\n\u003Cp>First, we need to ask what ‘enhancement’ exactly is. Throughout history, the enhancement of humans by various tools from physical addendums (remember \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.primaryancientgreeks.com\u002Fcontent\u002Fdaidalos-ikaros\" target=\"_blank\">Icaros\u003C\u002Fa>?) to drugs (from ferocious Viking “\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.historyextra.com\u002Fperiod\u002Fviking\u002Fthe-truth-about-viking-berserkers\u002F\" target=\"_blank\">berserkers\u003C\u002Fa>” to the Nazi army or East German swimmers – or many of the cyclists still today), or even love (just google ‘\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fen.wikipedia.org\u002Fwiki\u002FSacred_Band_of_Thebes\" target=\"_blank\">Sacred Band of Thebes\u003C\u002Fa>’) have been on the minds of leaders, military chiefs or inventors alike. Or \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=bxiKqA-u8y4&ab_channel=TheSchoolofLife\" target=\"_blank\">philosophers\u003C\u002Fa>, as a matter of fact. \u003C\u002Fp>\n\n\n\n\u003Cp>The urge to live forever has not passed with our predecessors, let’s take a look at Bryan Johnson’s Blueprint project with its straightforward goal: \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fprotocol.bryanjohnson.com\u002F\" target=\"_blank\">don’t die\u003C\u002Fa>. Granted, most of us don’t have 30 doctors and \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.bloomberg.com\u002Fnews\u002Ffeatures\u002F2023-01-25\u002Fanti-aging-techniques-taken-to-extreme-by-bryan-johnson?accessToken=eyJhbGciOiJIUzI1NiIsInR5cCI6IkpXVCJ9.eyJzb3VyY2UiOiJTdWJzY3JpYmVyR2lmdGVkQXJ0aWNsZSIsImlhdCI6MTY3NDc1MjE5MiwiZXhwIjoxNjc1MzU2OTkyLCJhcnRpY2xlSWQiOiJSUDFGV0xEV1JHRzQwMSIsImJjb25uZWN0SWQiOiJFNUUzM0M0NzlCOTA0MjU2OTRGRTU1NTg5OTQ4N0FBOSJ9.cWlkQxMxDlCY3A2nkIt6Fy2fciMLM0nsY8uS2T7Vhug&sref=nPlhheXZ\" target=\"_blank\">millions of dollars\u003C\u002Fa> to spend on enhancing ourselves in all possible ways. On top of that, I feel a slight contrast between his efforts and the initiative to sell extra virgin olive oil as the omnipotent elixir to the less fortunate. But we can’t deny he has gone the extra mile in every possible way to make the most of what money and science offer today and I truly appreciate the dedication here. \u003C\u002Fp>\n\n\n\n\u003Cp>However, biological enhancement is a much deeper issue.  \u003C\u002Fp>\n\n\n\n\u003Cp>The dawn of digital health brought an era of technological advancements and within, the recreation of the human body or body parts or -functions came within reach. It started as a restoration of a certain human function, like \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.asrs.org\u002Fretina-times\u002Fdetails\u002F131\u002Ffda-approves-world-first-artificial-retina\" target=\"_blank\">eyesight\u003C\u002Fa> or \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.uclhospitals.brc.nihr.ac.uk\u002Fresearch\u002Fprogrammes\u002Fdeafness-hearing-problems\" target=\"_blank\">hearing\u003C\u002Fa>, or the replacement of a missing limb. Technologies like CRISPR gene editing, nanotechnology and even the revolution of wearables and sensors brought new possibilities in human enhancement, and although longevity is still far away for many, living longer and possibly healthier is a de facto case for the human race. (That is, if we survive the climate catastrophe we created.) \u003C\u002Fp>\n\n\n\n\u003Cp>The science of it also has a philosophical backing called \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fen.wikipedia.org\u002Fwiki\u002FTranshumanism\" target=\"_blank\">transhumanism\u003C\u002Fa>; a movement that “\u003Cem>advocates the enhancement of the human condition by developing and making widely available sophisticated technologies that can greatly enhance longevity and cognition.\u003C\u002Fem>” The concept states that humankind will evolve into a new intelligent species. That is yet to be seen, however: current affairs indicate no such evolution. But \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.bbc.com\u002Fnews\u002Fuk-scotland-49893869\" target=\"_blank\">transhumanists\u003C\u002Fa> live and\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.forbes.com\u002Fsites\u002Fcalumchace\u002F2023\u002F02\u002F01\u002Fpioneering-transhumanism-a-conversation-with-natasha-vita-more\u002F\" target=\"_blank\"> strive among us\u003C\u002Fa>. And sometimes episodes of the series \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-future-of-our-brains-health-in-black-mirror\" target=\"_blank\">Black Mirror\u003C\u002Fa> have more links to reality than we wish. To know more, read our \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fzoltan-istvan-and-the-jesus-singularity\u002F\" target=\"_blank\">in-depth interview\u003C\u002Fa> with one of the world’s most influential transhumanists, Zoltan Istvan!\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"489\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F039_blackmirror-1.png\" alt=\"Black Mirror\" class=\"wp-image-22306\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F039_blackmirror-1.png 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F039_blackmirror-1-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F039_blackmirror-1-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002F039_blackmirror-1-512x288.png 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>There is a variety of fields where a superhuman feature could potentially be created. And that will not be the result of a single discipline but of the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fobamawhitehouse.archives.gov\u002Fsites\u002Fdefault\u002Ffiles\u002Fmicrosites\u002Fostp\u002Fbioecon-%28%23%20023SUPP%29%20NSF-NBIC.pdf\" target=\"_blank\">convergence\u003C\u002Fa> of multiple scientific fields. Currently, these have a restorative focus rather than a developmental one, although each can evolve towards that in the future. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Ffrom-human-to-cyborg\" target=\"_blank\">In this article\u003C\u002Fa>, we split the possible directions into 3 main categories:\u003C\u002Fp>\n\n\n\n\u003Col class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Removable cyborg extensions\u003C\u002Fstrong> – the tools enhancing the individual can easily be put away at the end of use\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Cyborg-humans\u003C\u002Fstrong> – technologies causing lasting, but not irreversible transformation like prosthetic limbs, digital tattoos and bionic implants\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Technologies changing humans forever\u003C\u002Fstrong> – genetic editing (such as CRISPR) is the one that raises the most ethical and \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-most-pressing-issues-in-bioethics\" target=\"_blank\" rel=\"noreferrer noopener\">moral questions\u003C\u002Fa>.\u003C\u002Fli>\n\u003C\u002Fol>\n\n\n\n\u003Cp>\u003Cstrong>This time we categorize the possibilities for enhancements horizontally and have a look at 5 fields where human enhancements would be possible.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">1. Brainpower\u003C\u002Fh2>\n\n\n\n\u003Cp>A microchip in the brain that will enhance our cognitive functions by a zillion – how we all could use such a thing during exams! The concept was first raised back in 1968 by architect Nicholas Negroponte at MIT, and it has come a long way since. Hacking the human brain is more difficult than we could imagine and cannot be solved with a single microchip implant. \u003C\u002Fp>\n\n\n\n\u003Cp>But Elon Musk’s \u003Cem>other\u003C\u002Fem> company, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fneuralink.com\u002Fapproach\u002F\" target=\"_blank\">Neuralink\u003C\u002Fa> aims to do just that. The idea is to have a chip implanted in one’s brain; that neural implant will let you control a computer or mobile device anywhere you go. A lot of water has passed under the bridge since Musk \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=CLUWDLKAF1M\" target=\"_blank\">presented the pigs with the implants\u003C\u002Fa> and in 2023 the company is \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.theverge.com\u002F2023\u002F9\u002F19\u002F23880861\u002Fneuralink-human-clinical-trial-n1-implant\" target=\"_blank\">recruiting human candidates\u003C\u002Fa> with quadriplegia for a six-year clinical trial. \u003C\u002Fp>\n\n\n\n\u003Cp>But seeing what Elon Musk did to that poor pig, it did not at all look like the future. We at The Medical Futurist often say that before the digital health transformation, a cultural shift is inevitable. But having a neural implant somehow gives me the creeps – even if it could give me superpowers.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">2. Brain-computer interface\u003C\u002Fh2>\n\n\n\n\u003Cp>With less media hype, Synchron, a company that has developed a minimally invasive brain-computer interface is further along the way. Their implant actually has been working in at least two patients for quite a long time and has now enrolled six patients with severe quadriparesis. The current trial runs in three clinical trial sites in the US. The Synchron implant does not require open brain surgery as it is implanted in the blood vessel on the surface of the motor cortex of the brain via the jugular vein, through a minimally-invasive endovascular procedure. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"A Brain Implant That Turns Your Thoughts Into Text | Tom Oxley | TED\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002F7Fiaew7nDmE?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Once implanted, it is designed to detect and wirelessly transmit motor intent out of the brain, intended to restore the capability for severely paralysed patients to control personal devices with hands-free point-and-click.\u003C\u002Fp>\n\n\n\n\u003Cp>Researchers have been investigating the possibilities of brain-computer interfaces or BCIs for quite a while now. At first, these were thought to be tools on one hand to provide constant monitoring of the brain’s electrical activity; this could support a wide range of applications from monitoring epilepsy or ADHD to pain management and sleep assessment. On the other hand, the concept was thought to be a \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fhbr.org\u002F2020\u002F10\u002Fwhat-brain-computer-interfaces-could-mean-for-the-future-of-work\" target=\"_blank\">solution for paralysed people\u003C\u002Fa> to move and control things around them with only thoughts… Taking it onto the next level, such an implant could also be used as an external hard drive for the mind.\u003C\u002Fp>\n\n\n\n\u003Cp>Enhancing cognitive performance would be able to change the lives of millions suffering from memory loss, and neurological or psychological disorders. Restorative processes like stroke rehabilitation would also gain from the technology. Or, as a matter of fact, these can help reduce the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.frontiersin.org\u002Farticles\u002F10.3389\u002Ffnins.2020.00692\u002Ffull\" target=\"_blank\">cognitive effects of ageing\u003C\u002Fa>. No wonder there are many studies that focus on the possibilities such technology can provide \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC7339951\u002F\" target=\"_blank\">for seniors\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">3. Muscle strength and robotic exoskeletons\u003C\u002Fh2>\n\n\n\n\u003Cp>There is a huge cultural acceptance issue with technological solutions for restoration vs. tech for boosting performance. According to a \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fblogs.scientificamerican.com\u002Fobservations\u002Fwhat-americans-think-of-human-enhancement-technologies\u002F\" target=\"_blank\">study on the matter\u003C\u002Fa>, the public almost unanimously agrees with technological enhancement if it’s used for restorative purposes: 95% support physical restorative applications, and 88% support cognitive restorative applications. But when it comes to the enhancement of human capabilities for the reason of boosting performance – well, that’s a big no-no, according to the study. Only 35% of respondents agree with the concept.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"Paralysed Man Completes London Marathon 2018\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FaB0pfAL6MdU?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Robotic exoskeletons are also becoming more and more common. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.sciencedirect.com\u002Ftopics\u002Fengineering\u002Fexoskeleton-robotics\" target=\"_blank\">Paralyzed\u003C\u002Fa> people or those who lost a limb have now the chance to move again with such technological advancements. Certain industries like \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fdozr.com\u002Fblog\u002Fconstruction-exoskeletons\u002F\" target=\"_blank\">construction\u003C\u002Fa> also make use of the extra power robotics can give. The next step will be the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-future-of-prosthetics-depends-on-a-i\u002F\" target=\"_blank\">AI-powered prosthesis\u003C\u002Fa>; or ones that can supplement healthy individuals with additional limbs. Not to mention a future where we \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fyoutu.be\u002FWTdfTupF7fs\" target=\"_blank\">share bodies and senses\u003C\u002Fa> with machines.\u003C\u002Fp>\n\n\n\n\u003Cp>But what are advanced technologies worth if only the wealthiest can afford them? That has been the case with many exoskeletons therefore it’s so great to see \u003Ca href=\"https:\u002F\u002Fwww.therobotreport.com\u002Frewalk-robotics-announces-solidified-medicare-coverage-for-personal-exoskeleton\u002F\">more and more covered by health insurance\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cp>In 2023 October ReWalk Robotics, Inc. announced that the Centers for Medicare & Medicaid Services (CMS) finalized a rule benefitting its exoskeleton technology. “Earlier this year, CMS released a proposal aiming to establish new regulatory definition of “brace.” Adding the definition of brace would expedite coverage and payment for newer technology and powered devices, according to CMS. This potentially enables faster access to the newer technologies, like those made by ReWalk and Myomo as well.”\u003C\u002Fp>\n\n\n\n\u003Cp>The new CMS proposal includes personal exoskeletons in the Medicare benefit category for braces meaning that benefits would extend to exoskeletons which allow paralyzed patients to stand and walk. This follows a \u003Ca href=\"https:\u002F\u002Fwww.therobotreport.com\u002Fexoskeletons-qualify-for-direct-disability-compensation-in-germany\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">similar announcement from Germany\u003C\u002Fa> from 2022. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">4. Enhancing the senses\u003C\u002Fh2>\n\n\n\n\u003Cp>What if technology could aid humans to have better hearing than bats? What if we could filter out the smell of urban decay and only experience pleasant odours? Or what if implants could let us see microscopic objects? Or special features, such as the heat map of an abandoned terrain? These questions led us to list how technology could help augment human senses in our previous article. One exciting example of this was the AI-supported hearing aid presented at the 2021 CES. This device features an onboard deep neural network that gives people with hearing loss a better experience. And there are many more examples of that.\u003C\u002Fp>\n\n\n\n\u003Cp>Supercharging human senses with \u003Ca href=\"https:\u002F\u002Fwww.medgadget.com\u002F2023\u002F11\u002Fglasses-provide-audible-prompts-for-blind-wearers.html\" target=\"_blank\" rel=\"noreferrer noopener\">technology for the blind\u003C\u002Fa> or the deaf are entirely feasible enhancements. When a person loses a sense, the area of the brain that was responsible for handling that sensory information does not go unused. The \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.jneurosci.org\u002Fcontent\u002F32\u002F28\u002F9626.abstract?sid=554f9c9c-ec7e-4c33-87a0-3f2416e52e24\" target=\"_blank\">brain rewires itself\u003C\u002Fa> and uses that area to process other senses. This is \u003Cem>neuroplasticity\u003C\u002Fem>, the ability of the brain to change with experience. Researchers “just” need to find out how to use this natural superpower.\u003C\u002Fp>\n\n\n\n\u003Cp>Temporary or long-term sensory enhancements are also not limited to the ones with certain disabilities: the technology goes beyond that. In the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Flink.springer.com\u002Freferenceworkentry\u002F10.1007%2F978-94-007-4707-4_106\" target=\"_blank\">Handbook of Neuroethics\u003C\u002Fa>, the authors explain that the enhancement tools “\u003Cem>could be implemented in mainly two ways: either via the application of digital technology or by genetic engineering of the human body\u003C\u002Fem>.” \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ericsson.com\u002Fen\u002Fblog\u002F2018\u002F7\u002Faugmented-reality-gives-us-super-human-abilities-and-a-sixth-sense\" target=\"_blank\">Augmented reality\u003C\u002Fa> just takes this realm a step further.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"One-minute Challenge: Augmented Reality - The Medical Futurist\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FxUaBrgsHkPs?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Augmented reality is not only \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Faugmented-reality-in-healthcare-will-be-revolutionary\u002F\" target=\"_blank\">revolutionary\u003C\u002Fa> but can also give us real superpowers. It is one of the most promising digital health technologies, from \u003Ca href=\"https:\u002F\u002Fwww.timesofisrael.com\u002Fin-global-first-shaare-zedek-spine-surgeon-combines-augmented-reality-with-robotics\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">operations\u003C\u002Fa> to providing \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fyoutu.be\u002FWg6jN-audEM\" target=\"_blank\">information\u003C\u002Fa> and \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fyoutu.be\u002FPzPKdlFbvYM\" target=\"_blank\">education\u003C\u002Fa>. Heightened capabilities of our vision by AR, VR, digital contact lenses or even retina chips have been bugging the minds of researchers for the past decade. And although many of the concepts \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Ffrom-theranos-to-google-glass-the-biggest-flops-in-digital-health\u002F\" target=\"_blank\">have failed\u003C\u002Fa> (remember Google’s glass or glucose-level measuring contact lenses?), these flops don’t necessarily mean the concepts are wrong.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">5. Genetic engineering – a brave new world?\u003C\u002Fh2>\n\n\n\n\u003Cp>A lot of research is underway in gene therapies. CRISPR editing was a huge step in this direction. While its original vision, to serve as a tool offering \u003Ca href=\"https:\u002F\u002Fwww.technologyreview.com\u002F2023\u002F03\u002F07\u002F1069475\u002Fforget-designer-babies-heres-how-crispr-is-really-changing-lives\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">gene therapies for patients\u003C\u002Fa> is noble and just, there is a significant, primarily moral and ethical resistance against the method. For example, researchers in Oxford’s Nuffield Laboratory of Ophthalmology \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fwww.ox.ac.uk\u002Fresearch\u002Fresearch-impact\u002Frestoring-sight-gene-therapy\" target=\"_blank\">help restore eyesight\u003C\u002Fa> to patients with genetic vision defects with gene therapy, which seems acceptable as a method; while genetic engineering \u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fnuffieldbioethics.org\u002F\" target=\"_blank\">on an embryo-level\u003C\u002Fa> is more of a moral issue than a scientific one.\u003C\u002Fp>\n\n\n\n\u003Cp>While CRISPR therapies are still considered experimental, and none have been approved, and some even have been unsuccessful, we’ve also seen \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.technologyreview.com\u002F2023\u002F03\u002F10\u002F1069619\u002Fmore-than-200-people-treated-with-experimental-crispr-therapies\u002F\" target=\"_blank\">some success stories\u003C\u002Fa> and several \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.technologyreview.com\u002F2023\u002F10\u002F25\u002F1082306\u002Fgene-editing-crispr-hiv-experiment\u002F\" target=\"_blank\">creepier announcements\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cp>Editing DNA can become a powerful tool in the diagnosis and the treatment of diseases. The European Union is trying to add the ethical component on the first level of its scientific programme in the genetic engineering leg of its human enhancement project. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fsienna-project.eu\u002Fgenomics\u002F\" target=\"_blank\">Sienna\u003C\u002Fa>, and other such organisations and projects also raise and include ethical issues in their projects. However, with such technologies becoming more available, cases like the creation of first \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.wsj.com\u002Farticles\u002Fhow-a-chinese-scientist-broke-the-rules-to-create-the-first-gene-edited-babies-11557506697\" target=\"_blank\">designer babies in China\u003C\u002Fa> appear. After this scandal, the WHO launched a global registry to track research on human genome editing.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Transhumanists predict that with the convergence of new technologies in science, we could create healthier, smarter and stronger humans. They think it’s our duty to evolve into something beyond ourselves. But as much as I love science, my idea of a happier life does not begin with being faster and stronger. It begins with the core values of humankind: empathy, tolerance and kindness. And if we can cure something or someone with the help of science, we should do that. But my brave new world shall not take place in \u003Cem>Gattaca\u003C\u002Fem>. \u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Ch5 class=\"wp-block-heading\">\u003Cstrong>Read more about these concepts in my book \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.amazon.com\u002FMy-Health-Revolutionary-Technologies-Healthier\u002Fdp\u002F6158026107\" target=\"_blank\">My Health Upgraded\u003C\u002Fa>, elaborating on where health care and medicine is heading in the future. \u003C\u002Fstrong>\u003C\u002Fh5>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Ca class=\"img\" href=\"https:\u002F\u002Fwww.amazon.com\u002FMy-Health-Revolutionary-Technologies-Healthier\u002Fdp\u002F6158026107\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"350\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F05\u002Flive-better-with-technology-myhealthupgraded-promo-768x350.png\" alt=\"Live better using technology - Buy My Health Upgraded\" class=\"wp-image-13211\"\u002F\u003C\u002Fa srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F05\u002Flive-better-with-technology-myhealthupgraded-promo-768x350.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F05\u002Flive-better-with-technology-myhealthupgraded-promo-512x233.png 512w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2016\u002F05\u002Flive-better-with-technology-myhealthupgraded-promo.png 870w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Fa>\u003Cfigcaption class=\"wp-element-caption\">Get it on Amazon\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Cp>\u003C\u002Fp>\n",{"rendered":1388,"protected":16},"\u003Cp>Enhancing human capabilities has been on the mind of people for ages, but superhumans came a long way from ancient training methods to exoskeletons. \u003C\u002Fp>\n",32183,{"_acf_changed":16,"footnotes":64},[840,691,1392,68,280,69,841,692,5,693,1393,694,173,1394,696],493,800,515,[1396,1397,1398,1399,1400],1120,1332,6525,231,639,[452,871],[],[1404,1405,1406,590,1407,1408,717,1409,302],2329,2541,3347,1617,1681,2017,[1411,53,116,117,118,119,120,880,721,1412,121,314,122,881,722,123,723,1413,724,1414,1415,726,1416,1417,1418,1419,1420,470,909],"post-32197","category-augmented-reality","category-healthcare-policy","category-robotics","category-science-fiction","tag-bci","tag-transhumanism","tag-neuralink","tag-exoskeleton","tag-brain-computer-interface",{"id":1389,"alt_text":64,"caption":64,"description":1422,"media_type":149,"media_details":1423,"post":1440,"source_url":1441},"Becoming superhuman ",{"width":332,"height":333,"file":1424,"sizes":1425,"image_meta":1439},"2021\u002F01\u002Ftmf_article_236-01.png",{"medium":1426,"large":1429,"thumbnail":1432,"medium_large":1435,"1536x1536":1436},{"file":1427,"width":179,"height":180,"mime-type":338,"source_url":1428},"tmf_article_236-01-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F01\u002Ftmf_article_236-01-370x208.png",{"file":1430,"width":182,"height":183,"mime-type":338,"source_url":1431},"tmf_article_236-01-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F01\u002Ftmf_article_236-01-768x432.png",{"file":1433,"width":177,"height":177,"mime-type":338,"source_url":1434},"tmf_article_236-01-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F01\u002Ftmf_article_236-01-150x150.png",{"file":1430,"width":182,"height":183,"mime-type":338,"source_url":1431},{"file":1437,"width":349,"height":350,"mime-type":338,"source_url":1438},"tmf_article_236-01-1536x864.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F01\u002Ftmf_article_236-01-1536x864.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},32095,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F01\u002Ftmf_article_236-01.png",{"cta_type":364,"cta_color":64,"subtitle":64,"related_posts_footer":1443,"related_posts":16,"related_books":1447,"key_takeaways":1448},[1444,1445,1446],53187,52933,53089,[366,939,1079],[1449,1451,1453],{"title":1450},"\u003Cp>Human enhancement has evolved from ancient methods to advanced technologies like exoskeletons and genetic editing, blurring the lines between science fiction and reality.\u003C\u002Fp>\n",{"title":1452},"\u003Cp>Current advancements in human enhancement, such as brain-computer interfaces and sensory augmentation, promise to revolutionize not just health but everyday human capabilities.\u003C\u002Fp>\n",{"title":1454},"\u003Cp>The ethical and philosophical considerations of human enhancement, especially in transhumanism, highlight the need to balance technological progress with fundamental human values and moral.\u003C\u002Fp>\n\u003Cp> \u003C\u002Fp>\n",{"yoast_wpseo_title":1384,"yoast_wpseo_metadesc":1456,"yoast_wpseo_canonical":1382},"Enhancing human capabilities has been on the mind of people for ages, but superhumans came a long way from ancient training methods to exoskeletons.",{"self":1458,"collection":1463,"about":1465,"author":1467,"replies":1469,"version-history":1472,"predecessor-version":1476,"wp:featuredmedia":1480,"wp:attachment":1483,"wp:term":1486,"curies":1497},[1459],{"href":1460,"targetHints":1461},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F32197",{"allow":1462},[27],[1464],{"href":220},[1466],{"href":223},[1468],{"embeddable":41,"href":226},[1470],{"embeddable":41,"href":1471},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=32197",[1473],{"count":1474,"href":1475},45,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F32197\u002Frevisions",[1477],{"id":1478,"href":1479},53721,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F32197\u002Frevisions\u002F53721",[1481],{"embeddable":41,"href":1482},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F32183",[1484],{"href":1485},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=32197",[1487,1489,1491,1493,1495],{"taxonomy":11,"embeddable":41,"href":1488},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=32197",{"taxonomy":248,"embeddable":41,"href":1490},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=32197",{"taxonomy":251,"embeddable":41,"href":1492},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=32197",{"taxonomy":254,"embeddable":41,"href":1494},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=32197",{"taxonomy":257,"embeddable":41,"href":1496},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=32197",[1498],{"name":39,"href":40,"templated":41},{"id":1500,"date":1501,"date_gmt":1502,"guid":1503,"modified":1505,"modified_gmt":1506,"slug":1507,"status":52,"type":53,"link":1508,"title":1509,"content":1511,"excerpt":1513,"author":61,"featured_media":1515,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1516,"categories":1517,"tags":1519,"project_category":1527,"contact_email_category":1528,"yst_prominent_words":1529,"class_list":1533,"better_featured_image":1543,"acf":1564,"yoast_meta":1577,"_links":1580},20749,"2023-10-26T10:00:00","2023-10-26T08:00:00",{"rendered":1504},"http:\u002F\u002Fmedicalfuturist.com\u002F?p=20749","2023-10-24T20:08:44","2023-10-24T18:08:44","googles-masterplan-for-healthcare","https:\u002F\u002Fmedicalfuturist.com\u002Fgoogles-masterplan-for-healthcare",{"rendered":1510},"Google’s Masterplan For Healthcare",{"rendered":1512,"protected":16},"\n\u003Cdiv class=\"wp-block-group\">\u003Cdiv class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n\u003Cdiv class=\"wp-block-group\">\u003Cdiv class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n\u003Cdiv class=\"wp-block-group\">\u003Cdiv class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n\u003Cdiv class=\"wp-block-group\">\u003Cdiv class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n\u003Cp>With \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.telegraph.co.uk\u002Ftechnology\u002F2019\u002F03\u002F10\u002Fgoogle-sifting-one-billion-health-questions-day\u002F\" target=\"_blank\">7% of Google searches\u003C\u002Fa> – or 70,000 per minute – being health-related a good number of years ago, it was only a matter of time before the search giant aimed to be a healthcare giant. Google hasn’t been particularly shy at expressing these ambitions: it \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fgoogles-acquisition-of-fitbit-boon-or-doom-for-the-fitness-tracking-industry\u002F\" target=\"_blank\">purchased Fitbit for $2.1 billion\u003C\u002Fa> and has a \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fdeepmind.com\u002Fblog\u002Fannouncements\u002Fdeepmind-health-joins-google-health\" target=\"_blank\">dedicated healthcare offshoot\u003C\u002Fa> from its AI branch, Deepmind. It is also the first company that publicly announced the development of a dedicated healthcare-specified AI model, called Med-PaLM. And as the variety of listed solutions on the \u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fhealth.google\u002F\" target=\"_blank\">Google Health page\u003C\u002Fa> shows, the company has something to offer to everyone, from patients and caregivers to communities, and researchers.  \u003C\u002Fp>\n\n\n\n\u003Cp>In this series exploring the latest moves by tech giants into healthcare, we recently analysed \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Famazon-in-healthcare-disruption-data-nightmares-and-digital-health-dreams\" target=\"_blank\">Amazon\u003C\u002Fa> and provided insights into the trends they are adopting. For now, let’s turn our focus on Google’s plan for the future of healthcare. Of note, we will treat Google, Alphabet, and Verily under the same umbrella. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">AI here, AI there, AI everywhere\u003C\u002Fh2>\n\n\n\n\u003Cp>Google is probably best known for the algorithmic prowess of its search engine. But since it acquired DeepMind, it has intended to expand this expertise elsewhere, \u003Ca href=\"https:\u002F\u002Fdeepmind.com\u002Fblog\u002Fannouncements\u002Fdeepmind-health-joins-google-health\" target=\"_blank\" rel=\"noreferrer noopener\">including healthcare\u003C\u002Fa>. And its efforts are showing promise.\u003C\u002Fp>\n\n\n\n\u003Cp>In August 2020, they \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fai.googleblog.com\u002F2020\u002F08\u002Fusing-machine-learning-to-detect.html\" target=\"_blank\">introduced C2D2\u003C\u002Fa>, a machine learning-based approach to improving colonoscopy screening. In the ensuing months, Google further put its AI as well as cloud computing expertise to use in new partnerships. In 2021, HCA Healthcare and Alphabet’s Google Cloud \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.cnbc.com\u002F2021\u002F05\u002F26\u002Fjim-cramer-googles-new-health-care-venture-is-reason-to-buy-alphabet.html\" target=\"_blank\">announced a collaboration\u003C\u002Fa> to develop algorithms to mine insights into patient records from the provider to improve efficiency and patient outcomes.\u003C\u002Fp>\n\n\n\n\u003Cp>Also launched in 2020, Google’s mammography AI system starts bringing in \u003Ca href=\"https:\u002F\u002Fwww.zdnet.com\u002Farticle\u002Fgoogle-health-expands-ai-powered-breast-cancer-screenings-integration\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">tangible results\u003C\u002Fa> by now. Recent studies show that using AI to support radiologists in breast cancer screening \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.zdnet.com\u002Farticle\u002Fai-can-conduct-breast-cancer-screenings-in-less-time-than-humans-but-just-as-well-study-finds\u002F\" target=\"_blank\">can significantly reduce screen reading workload\u003C\u002Fa> with comparable cancer detection efficiency as standard double-reading. \u003C\u002Fp>\n\n\n\n\u003Cp>But of course, in 2023 all eyes are on \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fgenerative-ai-explained-its-impact-and-future-in-healthcare\" target=\"_blank\">generative AI\u003C\u002Fa>. While Google may have seemed a little quiet during the ChatGPT craze, the company has set its focus on developing specialized models, like Med-PaLM, a large language model \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fmedpalm-new-ai-medical-chatbots-will-soon-be-better-than-waiting-for-a-doctor\u002F\">specifically designed to work in healthcare settings\u003C\u002Fa> and showing jaw-dropping \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fyoutu.be\u002F3Ud-BMOCkDI?si=w2aSDr_uykaMzz8x&t=279\" target=\"_blank\">improvements in accuracy\u003C\u002Fa> in its new, Med-PaLM 2 iteration.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-768x432.png\" alt=\"AI medical coding doctor, hospital, clinic, man, laptop, computer\" class=\"wp-image-51069\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365-2048x1152.png 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F06\u002Ftmf_article_365.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The model was not released to the general public. In the first round, it was accessible to Google Cloud customers in the healthcare and life sciences segment, such as HCA Healthcare, Mayo Clinic and Meditech. A while ago Google announced they are expanding this access to a\u003Ca href=\"https:\u002F\u002Fwww.healthcaredive.com\u002Fnews\u002Fgoogle-med-palm-ai-expansion-healthcare\u002F691677\u002F\" target=\"_blank\" rel=\"noreferrer noopener\"> wider circle of healthcare players\u003C\u002Fa>.  \u003C\u002Fp>\n\n\n\n\u003Cp>In October 2023 Google also revealed a new \u003Ca href=\"https:\u002F\u002Fwww.fiercehealthcare.com\u002Fhealth-tech\u002Fhlth23-google-cloud-rolls-out-new-generative-ai-search-tools-doctors-life-sciences\" target=\"_blank\" rel=\"noreferrer noopener\">AI-powered search tool designed for doctors and nurses\u003C\u002Fa>. According to the company, the medically-tuned generative AI-powered search is able to mine various data sources, including FHIR data, patients’ clinical notes, and other medical information.\u003C\u002Fp>\n\n\n\n\u003Cp>While Med-PaLM currently seems to be the most advanced of large language models in terms of healthcare accuracy, Google faces stiff competition. Microsoft, for instance, has secured its place in clinics with Nuance’s Dax and Dragon AI systems, tools used by hundreds of thousands of US doctors. When it comes to the cloud market, Google ranks fourth, trailing Amazon, Microsoft, and Alibaba. Nevertheless, the generative AI in healthcare race is still wide open, and \u003Ca href=\"https:\u002F\u002Fwww.forbes.com\u002Fsites\u002Fkatiejennings\u002F2023\u002F08\u002F29\u002Fgoogle-healthcare-generative-ai\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Google has lots of tricks\u003C\u002Fa> in its sleeves.  \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Google in the cloud\u003C\u002Fh2>\n\n\n\n\u003Cp>Maybe not the largest player in the cloud market, but Google has promising initiatives, like this one,\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.healthcareitnews.com\u002Fnews\u002Fgoogle-cloud-teams-carecloud-bring-generative-ai-small-practices\" target=\"_blank\"> lending much-needed processing power to smaller healthcare practices\u003C\u002Fa>. We already \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fcloud-gaming-can-bring-artificial-intelligence-to-the-doctors-office\u002F\" target=\"_blank\">discussed in great detail\u003C\u002Fa> how smaller healthcare entities will need cloud solutions to access advanced AI features as they won’t have the means to invest in cutting-edge hardware that is able to run state-of-the-art algorithms. Instead of expensive hardware upgrades, the processing power is handled remotely, thus physicians can ask complex clinical questions and gain deeper insights, with evidence-based recommendations derived from analysing datasets.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F05\u002Ftmf_article_362_AI_doctor_robot-768x432.png\" alt=\"\" class=\"wp-image-50863\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F05\u002Ftmf_article_362_AI_doctor_robot-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F05\u002Ftmf_article_362_AI_doctor_robot-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F05\u002Ftmf_article_362_AI_doctor_robot-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F05\u002Ftmf_article_362_AI_doctor_robot.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.healthcareitnews.com\u002Fnews\u002Fgoogle-cloud-teams-carecloud-bring-generative-ai-small-practices\" target=\"_blank\">Google-CareCloud cooperation\u003C\u002Fa> does exactly that: “By using Google’s offerings such as Vertex AI and Generative AI App Builder, the company is developing tools to bring physicians at smaller practices the same AI-enabled capabilities that are increasingly available at large hospitals and health systems.”\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Research endeavours\u003C\u002Fh2>\n\n\n\n\u003Cp>As it carried out research with its AI algorithms in healthcare, Google seems to have grown interested in broader, population-level medical research. In 2020, the tech giant launched Google Health Studies, an app dedicated to medical research. It allows any user to participate by reporting their symptoms, the steps they are taking to prevent getting ill, and if they’ve had relevant tests. Their first study was focusing on respiratory diseases like the flu and COVID-19.\u003C\u002Fp>\n\n\n\n\u003Cp>This approach can help provide researchers with more relevant patient data and from a larger pool. But it also raises privacy concerns over the handling of such data. Also, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fplay.google.com\u002Fstore\u002Fapps\u002Fdetails?id=com.google.android.apps.health.research.studies&hl=en&gl=US&pli=1\" target=\"_blank\">recent user reviews\u003C\u002Fa> are very far from enthusiastic. \u003C\u002Fp>\n\n\n\n\u003Cp>Nevertheless, Google seems determined to move forward with medical research. They \u003Ca href=\"https:\u002F\u002Fwww.fiercebiotech.com\u002Fmedtech\u002Fverily-taps-former-fda-deputy-commissioner-abernethy-to-lead-clinical-research-business\" target=\"_blank\" rel=\"noreferrer noopener\">appointed Dr. Amy Abernethy\u003C\u002Fa>, the FDA’s former principal deputy commissioner, as president of its Verily branch’s clinical research business in 2021. \u003Ca href=\"https:\u002F\u002Fwww.linkedin.com\u002Fin\u002Famyabernethy\u002Frecent-activity\u002Fall\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">She leads the development of a platform for clinical trials\u003C\u002Fa> and real-world evidence studies; as well as oversees Verily’s ongoing clinical research projects.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Point-of-care technologies projects\u003C\u002Fh2>\n\n\n\n\u003Cp>Just like Apple has a strong focus on turning patients into the point of care, Google is working on similar projects. In March 2021, Verily \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.fiercehealthcare.com\u002Fpayer\u002Falphabet-s-verily-joins-highmark-google-cloud-project-living-health\" target=\"_blank\">announced its partnership\u003C\u002Fa> with Highmark Health for the Living Health Initiative. The latter aims to redesign healthcare delivery with a focus on patients. This collaboration will employ Verily’s digitally-enabled tools for personalized chronic care management of conditions like congestive heart failure and chronic obstructive pulmonary disease.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F04\u002Ftmf_article_357-768x432.png\" alt=\"TMF, medical student, AI, doctor, data, computer\" class=\"wp-image-50547\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F04\u002Ftmf_article_357-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F04\u002Ftmf_article_357-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F04\u002Ftmf_article_357-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F04\u002Ftmf_article_357-2048x1152.png 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F04\u002Ftmf_article_357.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>In a rather unexpected move, Google decided to revisit a healthcare area it previously failed to pierce into: health records. In April 2021, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.statnews.com\u002F2021\u002F04\u002F09\u002Fgoogle-health-records-app-care-studio\u002F\" target=\"_blank\">\u003Cem>Stat News\u003C\u002Fem> reported\u003C\u002Fa> that the tech giant is working on \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.healthcaredive.com\u002Fnews\u002Fgoogle-user-testing-personal-health-record\u002F636667\u002F\" target=\"_blank\">a consumer-facing medical records tool\u003C\u002Fa> to make it easier for patients to see, organise, and share their health data.\u003C\u002Fp>\n\n\n\n\u003Cp>The move was rather unexpected because the company already had a similar venture that was \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.theverge.com\u002F2021\u002F4\u002F12\u002F22379846\u002Fgoogle-health-record-data-app-android\" target=\"_blank\">shut down in 2012\u003C\u002Fa>. Again, this is a field that has multiple tech companies’ interest, for example, Apple has been working on the electronic medical records-health app integration \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.informationweek.com\u002Fit-leadership\u002Fapple-partners-with-epic-mayo-clinic-for-healthkit\" target=\"_blank\">for a few years\u003C\u002Fa>, with mixed results.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">Regulatory setback and refocus \u003C\u002Fh2>\n\n\n\n\u003Cp>Like its competitors, Google has also faced some setbacks in the past few years. The FDA \u003Ca href=\"https:\u002F\u002Fwww.healthcaredive.com\u002Fnews\u002Ffda-rejects-verily-filing-for-wrist-worn-parkinsons-clinical-trial-device-google\u002F602015\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">rejected Verily’s request\u003C\u002Fa> to use its wearable in a clinical trial to monitor alterations in motor symptoms of patients with Parkinson’s. The regulatory body \u003Ca href=\"https:\u002F\u002Fwww.healthcaredive.com\u002Fnews\u002Ffda-rejects-verily-filing-for-wrist-worn-parkinsons-clinical-trial-device-google\u002F602015\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">did clear Verily’s device\u003C\u002Fa> to monitor ECG and irregular pulse but rejected the request for this new feature. FDA \u003Ca href=\"https:\u002F\u002Fwww.healthcaredive.com\u002Fnews\u002Ffda-rejects-verily-filing-for-wrist-worn-parkinsons-clinical-trial-device-google\u002F602015\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">said that\u003C\u002Fa> the device and associated motor examination “are limited in their capacity to evaluate meaningful aspects of concepts of interest that are relevant to the patients’ ability to function in day-to-day life.” \u003C\u002Fp>\n\n\n\n\u003Cp>Business Insider \u003Ca href=\"https:\u002F\u002Fwww.businessinsider.com\u002Fgoogle-health-splitting-reorganization-sending-employees-fitbit-search-2021-6?r=US&IR=T\" target=\"_blank\" rel=\"noreferrer noopener\">released an exclusive report\u003C\u002Fa> in 2021 detailing how the company has moved Google Health employees to other groups within the company. The Google Health branch will no longer focus on consumer tech, as this is \u003Ca href=\"https:\u002F\u002Fwww.mobihealthnews.com\u002Fnews\u002Fgoogle-downsizes-health-division-reorganizes-consumer-health-team\" target=\"_blank\" rel=\"noreferrer noopener\">mainly driven by the Fitbit team\u003C\u002Fa>. With Google revisiting old projects, refocusing its health team’s efforts and announcing new partnerships, it seems like the tech giant’s healthcare plans are all over the place. But this might be because Google indeed wants to be everywhere in healthcare.\u003C\u002Fp>\n\n\n\n\u003Cp>However, the latest developments indicate that the most promising avenues for the company are AI, remote monitoring software, and cloud computing. But Google is also notorious for pulling the plug on even the most ambitious projects of its projects. The \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fkilledbygoogle.com\u002F\" target=\"_blank\">Google Graveyard\u003C\u002Fa> is a testament to that.\u003C\u002Fp>\n\n\n\n\u003Cp>So, it’s safe to say that we shouldn’t get too attached to a project set forth by Google, even if it could revolutionise healthcare. But we can expect the tech giant to keep branching out in various areas of healthcare as it aims to have a strong foothold on the market.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cem>Written by Dr. Bertalan Meskó & Dr. Pranavsingh Dhunnoo\u003C\u002Fem>\u003C\u002Fp>\n\u003C\u002Fdiv>\u003C\u002Fdiv>\n\u003C\u002Fdiv>\u003C\u002Fdiv>\n\u003C\u002Fdiv>\u003C\u002Fdiv>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n\u003C\u002Fdiv>\u003C\u002Fdiv>\n",{"rendered":1514,"protected":16},"\u003Cp>AI for medical use, cloud services for healthcare practices, apps for research – Google is everywhere in the digital health field. But the competition is fierce, and the race is still wide open. \u003C\u002Fp>\n",35327,{"_acf_changed":16,"footnotes":64},[691,841,441,281,5,693,844,1518],799,[82,1520,1521,1522,1523,704,84,1153,1524,88,862,700,83,1012,1525,1526,78,80],6055,266,7279,531,806,936,207,[709,453,871],[],[590,101,591,105,1530,1531,592,107,1532,1030],1729,1797,2351,[1534,53,116,117,118,119,120,721,881,461,315,123,723,884,1535,135,1536,1537,1538,1539,733,137,1182,1540,141,901,729,136,1041,1541,1542,131,133,737,471,909],"post-20749","category-security-privacy","tag-deepmind","tag-google-2","tag-alphabet","tag-google-deepmind","tag-tech","tag-verily","tag-digital-health",{"id":1515,"alt_text":64,"caption":64,"description":1544,"media_type":149,"media_details":1545,"post":1562,"source_url":1563},"Google’s Masterplan for Healthcare",{"width":332,"height":333,"file":1546,"sizes":1547,"image_meta":1561},"2021\u002F08\u002Ftmf_article_281-02.png",{"medium":1548,"large":1551,"thumbnail":1554,"medium_large":1557,"1536x1536":1558},{"file":1549,"width":179,"height":180,"mime-type":338,"source_url":1550},"tmf_article_281-02-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F08\u002Ftmf_article_281-02-370x208.png",{"file":1552,"width":182,"height":183,"mime-type":338,"source_url":1553},"tmf_article_281-02-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F08\u002Ftmf_article_281-02-768x432.png",{"file":1555,"width":177,"height":177,"mime-type":338,"source_url":1556},"tmf_article_281-02-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F08\u002Ftmf_article_281-02-150x150.png",{"file":1552,"width":182,"height":183,"mime-type":338,"source_url":1553},{"file":1559,"width":349,"height":350,"mime-type":338,"source_url":1560},"tmf_article_281-02-1536x864.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F08\u002Ftmf_article_281-02-1536x864.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},34907,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F08\u002Ftmf_article_281-02.png",{"related_posts":16,"related_posts_footer":1565,"subtitle":64,"cta_type":364,"cta_color":64,"related_books":1569,"key_takeaways":1570},[1566,1567,1568],52901,42091,47151,[1079,509],[1571,1573,1575],{"title":1572},"\u003Cp>Google is intensifying its focus on healthcare, leveraging its AI capabilities, with significant advancements like the Med-PaLM model and a new AI-powered search tool specifically designed for medical professionals.\u003C\u002Fp>\n",{"title":1574},"\u003Cp>Despite its efforts, Google faces stiff competition in multiple healthcare segments, preventing it from being unequivocally declared as the leader in any specific area.\u003C\u002Fp>\n",{"title":1576},"\u003Cp>Google’s track record of discontinuing projects warrants caution, suggesting that while its ambitions are vast, not all ventures may have enduring impacts.\u003C\u002Fp>\n",{"yoast_wpseo_title":1578,"yoast_wpseo_metadesc":1579,"yoast_wpseo_canonical":1508},"Google's Masterplan For Healthcare - The Medical Futurist","Google in healthcare: with about 70,000 health-related searches per minute, the tech giant knows what people want. And it's ready to give them.",{"self":1581,"collection":1586,"about":1588,"author":1590,"replies":1592,"version-history":1595,"predecessor-version":1599,"wp:featuredmedia":1603,"wp:attachment":1606,"wp:term":1609,"curies":1620},[1582],{"href":1583,"targetHints":1584},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F20749",{"allow":1585},[27],[1587],{"href":220},[1589],{"href":223},[1591],{"embeddable":41,"href":226},[1593],{"embeddable":41,"href":1594},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=20749",[1596],{"count":1597,"href":1598},50,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F20749\u002Frevisions",[1600],{"id":1601,"href":1602},53147,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F20749\u002Frevisions\u002F53147",[1604],{"embeddable":41,"href":1605},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F35327",[1607],{"href":1608},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=20749",[1610,1612,1614,1616,1618],{"taxonomy":11,"embeddable":41,"href":1611},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=20749",{"taxonomy":248,"embeddable":41,"href":1613},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=20749",{"taxonomy":251,"embeddable":41,"href":1615},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=20749",{"taxonomy":254,"embeddable":41,"href":1617},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=20749",{"taxonomy":257,"embeddable":41,"href":1619},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=20749",[1621],{"name":39,"href":40,"templated":41},{"id":933,"date":1623,"date_gmt":1624,"guid":1625,"modified":1627,"modified_gmt":1628,"slug":1629,"status":52,"type":53,"link":1630,"title":1631,"content":1633,"excerpt":1635,"author":61,"featured_media":1637,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1638,"categories":1639,"tags":1640,"project_category":1648,"contact_email_category":1649,"yst_prominent_words":1650,"class_list":1654,"better_featured_image":1663,"acf":1686,"yoast_meta":1698,"_links":1700},"2023-08-17T10:00:00","2023-08-17T08:00:00",{"rendered":1626},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=24858&_wpnonce=7146ccf2fa&status=auto-draft&type=post","2023-08-17T09:36:42","2023-08-17T07:36:42","top-companies-using-a-i-in-drug-discovery-and-development","https:\u002F\u002Fmedicalfuturist.com\u002Ftop-companies-using-a-i-in-drug-discovery-and-development",{"rendered":1632},"Top 6 Companies Using AI In Drug Discovery And Development",{"rendered":1634,"protected":16},"\n\u003Cdiv class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n\u003Cdiv class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:100%\">\n\u003Cp>What if coming up with a new drug could be measured in days rather than years? What if new medication would cost thousands instead of billions of dollars? Just look at how an AI pharma start-up \u003Ca href=\"https:\u002F\u002Fwww.technologyreview.com\u002Ff\u002F614251\u002Fan-ai-system-identified-a-potential-new-drug-in-just-46-days\u002F\">developed a potential new drug in 46 days\u003C\u002Fa>! Artificial intelligence technologies \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-future-of-clinical-trials-artificial-patients-synthetic-data-and-real-time-analysis\" target=\"_blank\">promise to speed up the process\u003C\u002Fa> of drug discovery and development and make it more cost-effective. As the market is flourishing, and it takes time and effort to separate the wheat from the chaff, we collected the most promising AI pharma companies out there.\u003C\u002Fp>\n\n\n\n\u003Cp>Drug design is a key area AI is revolutionizing. In one of our latest database projects, we decided to venture into this territory and collect the companies that use artificial intelligence for this purpose. To add more value than what’s already available, our goal was not only to list these but also to determine their fields of operation, their target group and other, so far unmapped details.\u003C\u002Fp>\n\u003C\u002Fdiv>\n\u003C\u002Fdiv>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>The future is about speed and savings\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>New drugs are approved through human clinical trials: rigorous,\nyear-long procedures starting in animal trials and gradually moving to\npatients. They typically cost billions of dollars and take many years to\ncomplete, sometimes more than a decade. Plus, patients in trials are exposed to\nside effects that cannot be predicted or expected. And even if the trial is\nsuccessful, it has to go through a regulatory approval: it may or may not\nreceive the nod of the respective regulatory agency, e.g. the US Food and Drugs\nAdministration (FDA).\u003C\u002Fp>\n\n\n\n\u003Cp>Luckily, there’s an abundance of technologies and companies that want to change the status quo. One way to \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Ffuture-of-clinical-trials\" target=\"_blank\">modernise the drug testing process\u003C\u002Fa> is applying technologies to the traditional framework, for example, through online platforms to seek out participants; while an alternative way is to use \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwyss.harvard.edu\u002Ftechnology\u002Fhuman-organs-on-chips\u002F\" target=\"_blank\">human organs-on-chips\u003C\u002Fa> or \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fin-silico-trials-are-the-future\u002F\" target=\"_blank\">in silico trials\u003C\u002Fa>. These all aim to speed up the process, save thousands of dollars and unburden patients. \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>However, when looking at all these technologies, artificial intelligence is the most advanced and most multifaceted. The technology helps companies aggregate and synthesize a lot of information that’s needed for clinical trials, thus shortening the drug development process. It can also help understand the mechanisms of the disease, establish biomarkers, generate data, models, or novel drug candidates, design or redesign drugs, run preclinical experiments, design and run clinical trials, and even analyse the real-world experience\u003C\u002Fstrong>. \u003C\u002Fp>\n\n\n\n\u003Cp>The number of already existing AI companies in drug development reflects the manifold usage of the technology: they are many and increasing day by day. \u003C\u002Fp>\n\n\n\n\u003Cp>Nevertheless, we managed to choose our six favorites, so here you go!\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">1) The company that mines clinical trials: \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.antidote.me\u002F\" target=\"_blank\">Antidote\u003C\u002Fa>\u003C\u002Fh2>\n\n\n\n\u003Cp>US and UK-based Antidote is focusing on matching patients and medical researchers in clinical trials so they could work together more easily. \u003Cstrong>The platform allows patients to find the most suitable clinical trials, helps researchers stream their latest study information to millions of patients, and even connects them with members of the medical community directly\u003C\u002Fstrong>. It’s basically a very efficient online platform for enhancing access to clinical trials.\u003C\u002Fp>\n\n\n\n\u003Cp>By combining proprietary technologies, data, and well-established business models, the company is transforming the way patients and researchers connect so that breakthroughs can happen faster. The company was launched under the name of TrialReach in 2010, but it got rebranded to Antidote in 2016. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">2) The company with tangible results: \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.atomwise.com\u002F\" target=\"_blank\">Atomwise\u003C\u002Fa>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cstrong>The most well-known company in drug discovery aims to reduce the costs of medicine development by using supercomputers to predict from a database of molecular structures in advance which potential medicines will work, and which won’t\u003C\u002Fstrong>. Their deep convolutional neural network, AtomNet, screens more than 100 million compounds each day.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F09\u002Ftmf_article_291_A-02-768x432.png\" alt=\"\" class=\"wp-image-36305\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F09\u002Ftmf_article_291_A-02-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F09\u002Ftmf_article_291_A-02-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F09\u002Ftmf_article_291_A-02-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F09\u002Ftmf_article_291_A-02.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>In 2015, Atomwise launched a virtual search for safe, existing medicines that could be redesigned to treat the Ebola virus. They found two drug candidates predicted by the company’s AI technology which may significantly reduce Ebola infectivity. This analysis, which typically would have taken months or years, was completed in less than one day! Imagine how efficient drug creation would become if such clinical trials could be run at the “ground zero” level of health care, namely in pharmacies.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">3) The company that concentrates on cancer drugs: \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.welcome.ai\u002Fturbine-ai\" target=\"_blank\">Turbine.AI\u003C\u002Fa>\u003C\u002Fh2>\n\n\n\n\u003Cp>A dedicated team of A.I. developers, medical professionals, and bioinformaticians has spent 6 years researching and building an artificial intelligence solution to design personalised treatments for any cancer type or patient faster than any traditional healthcare service. \u003Cstrong>The technology models cell biology on the molecular level, it can identify the best drug to target a specific tumor with; moreover, it identifies complex biomarkers and design combination therapies by performing millions of simulated experiments each day.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\">\u003Cdiv class=\"wp-block-embed__wrapper\">\n\u003Ciframe loading=\"lazy\" title=\"AI Case Studies In Pharmaceutical Drug Design  - Live Q&A With The Medical Futurist\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FcSrwgtEAzLQ?start=1045&feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\n\u003C\u002Fdiv>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The key to Turbine’s uniqueness is its molecular model of cancer biology guided by an AI to identify the biomarkers that signal sensitivity to treatment. As a result, the technology is already used in collaborations with Bayer, the University of Cambridge and top Hungarian research groups to find new cancer cures, speed up the time to market them and save the lives of patients suffering from currently incurable forms of the lethal disease.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">4) The company with a comprehensive structure from genomic to clinical data\u003Cstrong>: \u003C\u002Fstrong>\u003Ca rel=\"noreferrer noopener\" href=\"http:\u002F\u002Fprecisionlife.com\u002F\" target=\"_blank\">Row Analytics\u003C\u002Fa>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cstrong>The Oxford-based data analytics company operating since 2013 specializes in digital health, precision medicine, genomics, and semantic search\u003C\u002Fstrong>. It is delivering a range of highly innovative data analytics platforms, for example, PrecisionLife for drug discovery.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>The platform combines AI methods and data analytics to look at multiple genetic variants in combinations across a range of diseases\u003C\u002Fstrong>. As they are able to complete the process in weeks instead of months, even for large disease populations with tens of thousands of patients, this enables the rapid identification of novel drug candidates and potential drugs to repurpose. \u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">5) The company with research excellence in in-silico genomics: \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.deepgenomics.com\u002F\" target=\"_blank\">Deep Genomics\u003C\u002Fa>\u003C\u002Fh2>\n\n\n\n\u003Cp>Brendan Frey’s company promises \u003Cstrong>to solve the biggest puzzle in genetics: to get to know exactly what information the genome could provide for patients, medical professionals, and researchers. For doing so, Deep Genomics is \u003Ca href=\"http:\u002F\u002Fwww.businessinsider.com\u002Fhow-deep-genomics-is-using-ai-to-solve-genetic-mysteries-2015-9\" target=\"_blank\" rel=\"noreferrer noopener\">leveraging AI, specifically deep learning to help decode the meaning of the genome\u003C\u002Fa>\u003C\u002Fstrong>.\u003C\u002Fp>\n\n\n\n\u003Cp>So far, the company has used its computational system to develop a database that provides predictions for more than 300 million genetic variations that could affect the genetic code. For this reason, their findings are used for genome-based therapeutic development, molecular diagnostics, targeting biomarker discovery and assessing risks for genetic disorders.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">6) The company with drug discovery in 46 days: \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Finsilico.com\u002F\" target=\"_blank\">Insilico Medicine\u003C\u002Fa>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cstrong>As an artificial intelligence company for drug discovery, biomarker development, and ageing research, Insilico Medicine aims to cover the entire process of drug discovery, clinical trials analysis, and digital medicine\u003C\u002Fstrong>. It is pursuing internal drug discovery programs in cancer, dermatological diseases, fibrosis, Parkinson’s Disease, Alzheimer’s Disease, ALS, diabetes, sarcopenia, and ageing.\u003C\u002Fp>\n\n\n\n\u003Cp>The company, working with researchers at the University of Toronto, \u003Cstrong>made headlines lately with the announcement that the process of developing a new drug candidate lasted just 46 days with the help of its smart algorithm\u003C\u002Fstrong>. At first, it took \u003Ca href=\"https:\u002F\u002Fwww.technologyreview.com\u002Ff\u002F614251\u002Fan-ai-system-identified-a-potential-new-drug-in-just-46-days\u002F\">21 days for the team to create 30,000 designs for molecules\u003C\u002Fa> that target a protein linked with fibrosis (tissue scarring). They synthesized six of these molecules in the lab and then tested two in cells, the most promising one was tested in mice. The researchers concluded it was potent against the protein and showed “drug-like” qualities. The research was published in\u003Ca href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fs41587-019-0224-x\"> Nature Biotechnology\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n\n\n\n\u003Cp>\u003C\u002Fp>\n",{"rendered":1636,"protected":16},"\u003Cp>What if coming up with a new drug could be measured in days rather than years? What if new medication would cost thousands instead of billions of dollars? Artificial intelligence technologies promise to speed up the process of drug discovery and make it more cost-effective. As the market is flourishing, and it takes time and effort to separate the wheat from the chaff, we collected the most promising AI pharma companies out there.\u003C\u002Fp>\n",52039,{"_acf_changed":16,"footnotes":64},[691,281,5],[1641,700,1642,1012,286,1643,1644,295,1645,82,1646,1647,1153],566,568,173,1471,1472,1473,356,[],[],[1651,716,1652,592,107,1030,308,1653,876,101],1635,1739,1607,[1655,53,116,117,118,119,120,721,315,123,1656,729,1657,1041,319,1658,1659,328,1660,135,1661,1662,1182],"post-24858","tag-clinical-trials","tag-drug-development","tag-clinical","tag-drug-discovery","tag-drug-research","tag-cure","tag-pharma-2",{"id":1637,"alt_text":64,"caption":64,"description":64,"media_type":149,"media_details":1664,"post":1684,"source_url":1685},{"width":1665,"height":1666,"file":1667,"filesize":1668,"sizes":1669,"image_meta":1682},1500,844,"2023\u002F08\u002Ftmf_article_382-2-s.png",598938,{"medium":1670,"large":1674,"thumbnail":1678,"medium_large":1681},{"file":1671,"width":157,"height":158,"mime-type":338,"filesize":1672,"source_url":1673},"tmf_article_382-2-s-370x208.png",56575,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F08\u002Ftmf_article_382-2-s-370x208.png",{"file":1675,"width":163,"height":164,"mime-type":338,"filesize":1676,"source_url":1677},"tmf_article_382-2-s-768x432.png",168332,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F08\u002Ftmf_article_382-2-s-768x432.png",{"file":1679,"width":168,"height":168,"mime-type":338,"filesize":1500,"source_url":1680},"tmf_article_382-2-s-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F08\u002Ftmf_article_382-2-s-150x150.png",{"file":1675,"width":163,"height":164,"mime-type":338,"filesize":1676,"source_url":1677},{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188,"keywords":1683},[],null,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F08\u002Ftmf_article_382-2-s.png",{"related_posts_footer":1687,"related_posts":16,"cta_type":364,"cta_color":1691,"subtitle":64,"related_books":1692,"key_takeaways":1693},[1688,1689,1690],14131,15585,46538,"green",[939,770,1079],[1694,1696],{"title":1695},"\u003Cp>AI promises to disrupt drug discovery, radically speeding up the process and making it significantly cheaper\u003C\u002Fp>\n",{"title":1697},"\u003Cp>We collected the flagship companies of the field and also introduce our latest database project analysing this realm\u003C\u002Fp>\n",{"yoast_wpseo_title":1632,"yoast_wpseo_metadesc":1699,"yoast_wpseo_canonical":1630},"AI promises to speed up and make drug discovery and development more cost-effective. Here, we collected the most promising AI pharma companies.",{"self":1701,"collection":1706,"about":1708,"author":1710,"replies":1712,"version-history":1715,"predecessor-version":1719,"wp:featuredmedia":1723,"wp:attachment":1726,"wp:term":1729,"curies":1740},[1702],{"href":1703,"targetHints":1704},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F24858",{"allow":1705},[27],[1707],{"href":220},[1709],{"href":223},[1711],{"embeddable":41,"href":226},[1713],{"embeddable":41,"href":1714},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=24858",[1716],{"count":1717,"href":1718},29,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F24858\u002Frevisions",[1720],{"id":1721,"href":1722},52065,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F24858\u002Frevisions\u002F52065",[1724],{"embeddable":41,"href":1725},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F52039",[1727],{"href":1728},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=24858",[1730,1732,1734,1736,1738],{"taxonomy":11,"embeddable":41,"href":1731},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=24858",{"taxonomy":248,"embeddable":41,"href":1733},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=24858",{"taxonomy":251,"embeddable":41,"href":1735},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=24858",{"taxonomy":254,"embeddable":41,"href":1737},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=24858",{"taxonomy":257,"embeddable":41,"href":1739},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=24858",[1741],{"name":39,"href":40,"templated":41},{"id":1743,"date":1744,"date_gmt":1745,"guid":1746,"modified":1748,"modified_gmt":1749,"slug":1750,"status":52,"type":53,"link":1751,"title":1752,"content":1754,"excerpt":1756,"author":61,"featured_media":1758,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1759,"categories":1760,"tags":1761,"project_category":1765,"contact_email_category":1766,"yst_prominent_words":1767,"class_list":1770,"better_featured_image":1775,"acf":1804,"yoast_meta":1810,"_links":1813},48467,"2023-01-03T10:00:00","2023-01-03T09:00:00",{"rendered":1747},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=48467&_wpnonce=8e4788e6a4&status=auto-draft&type=post","2023-01-02T18:17:18","2023-01-02T17:17:18","the-global-nutrigenomics-landscape","https:\u002F\u002Fmedicalfuturist.com\u002Fthe-global-nutrigenomics-landscape",{"rendered":1753},"The Global Nutrigenomics Landscape",{"rendered":1755,"protected":16},"\n\u003Cp>Nutrigenomics – the DNA-backed science of what one should\u002Fshould not eat – is one of the most exciting promises in digital health. It has been, in fact, one of the most exciting promises \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fnutrigenomics\u002F\" target=\"_blank\">for at least five years\u003C\u002Fa>, if not more. And despite the expectations and advancement of DNA analysis, it still couldn’t live up to the high hopes. The field struggles to gain momentum and become a mainstream service used by the masses.\u003C\u002Fp>\n\n\n\n\u003Cp>There are a number of reasons why it is so, we \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fwhy-is-nutrigenomics-the-biggest-flop-in-digital-health\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">explained four factors in this article\u003C\u002Fa>. So where do we stand now? This was the main driving question behind one of our latest data projects: mapping out the nutrigenomics landscape.\u003C\u002Fp>\n\n\n\n\u003Cp>Our analyst colleague collected as much data as possible about available nutrigenomics service providers to paint an overview of what is available, where and for what price. You can dive deep into the details \u003Ca class=\"img\" href=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Fnutrigenomics-final_small.png\" target=\"_blank\" rel=\"noreferrer noopener\"\u003C\u002Fa>with our new infographic\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-style-default\">\u003Ca class=\"img\" href=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Fnutrigenomics-final_small.png\" target=\"_blank\" rel=\"noreferrer noopener\"\u003C\u002Fa>\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"1257\" height=\"1080\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F01\u002Fnutrigenomics-final_small.png\" alt=\"The Global Nutrigenomics Landscape 2022 TMF\" class=\"wp-image-48529\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F01\u002Fnutrigenomics-final_small.png 1257w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F01\u002Fnutrigenomics-final_small-768x660.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2023\u002F01\u002Fnutrigenomics-final_small-1536x1320.png 1536w\" sizes=\"auto, (max-width: 1257px) 100vw, 1257px\" \u002F>\u003C\u002Fa>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The goal was to find companies offering genetic tests and dietary information, advice and insights based on the genetic results. We found 41 providers selling dietary advice based on genetic results around the world. \u003C\u002Fp>\n\n\n\n\u003Cp>Not surprisingly, North-American customers are best served: 19 providers are located on the continent (17 in the USA and 2 in Canada). This is followed by Europe with 11 companies, located in the UK, Spain, Belgium, Ukraine and Finland. Asia has 5 providers in India, Malaysia and China. Three of the four African companies are located in South Africa, and one is in Egypt. Oceania and the Middle East have one provider each, in New Zealand and Israel respectively. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">So what can you expect from nutrigenomics now?\u003C\u002Fh3>\n\n\n\n\u003Cp>To provide a glimpse of what the field has to offer now, I’ve chosen 3 examples of the above 41. Here they are. \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Genopalate – you can upload your existing DNA test\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.genopalate.com\u002Fpages\u002Fgenobase\" target=\"_blank\" rel=\"noreferrer noopener\">Genopalate\u003C\u002Fa> is located in the US. The reason for picking them as an example is that they allow their users to upload the results of their existing genetics tests (from 23andMe and AncestryDNA). Although you can also take a test with them, using your already existing analysis will save you around 50% of the price. \u003C\u002Fp>\n\n\n\n\u003Cp>Their services are similar to other nutrigenomics companies: nutritional insights on 23 different nutrients (macronutrients and vitamins & minerals), the likelihood of gluten & lactose sensitivities, metabolism speed on alcohol & caffeine, a list of “genetics superfoods” (a recommendation list to find the ingredients that best match your DNA profile). They also promise that you will learn about your eating predispositions (like stress eating, various cravings, flavour preferences and your ideal breakfast time), and also how you can better manage stress levels with diet- and lifestyle-related decisions. \u003C\u002Fp>\n\n\n\n\u003Cp>Consultation with a registered dietitian is also available, but it’s not part of the basic packages, you need to purchase it as an extra, and it costs more than the actual test. The service is only available in the US. \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>DNAfit also works with existing DNA test results and you can check the sample nutrition report\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>With the UK-based \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.dnafit.com\u002Fstore\u002Fdietfit.asp\" target=\"_blank\">DNAfit\u003C\u002Fa> it’s not necessary to get an actual test done, as it also works with reports from the same two companies as above, and for a very low price. For under £30 you can get your report in under 30 minutes – they say. I haven’t tried it yet, but I would probably opt for the extended package (£50-ish) which promises diet, exercise and lifestyle recommendations based on the results of my existing DNA test.\u003C\u002Fp>\n\n\n\n\u003Cp>But back to the nutrigenomics offer. You can also start from scratch and have your DNA tested with them, and will receive the following info. \u003C\u002Fp>\n\n\n\n\u003Cp>Diet insight – 11 reports – to personalise how you eat. This includes data on sensitivities (carbohydrate, fat, salt, caffeine), data on coeliac predisposition, and alcohol response, among others. You will also get nutritional insights – 13 reports – focusing on vitamins and minerals. And you will receive a personalised meal plan, which is supposed to offer you recipes and shopping lists based on your genetics and personal preferences. \u003C\u002Fp>\n\n\n\n\u003Cp>According to the available data, they don’t offer in-person counselling, not even as an extra. Bonus: available in countries that many “big-name” providers don’t cover.  \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>CircleDNA comes with counselling\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>Hongkong-based \u003Ca href=\"https:\u002F\u002Fcircledna.com\u002Fvital\" target=\"_blank\" rel=\"noreferrer noopener\">CircleDNA\u003C\u002Fa> has an interesting take: their test is slightly more expensive than the other two above – and a lot cheaper than many on our list -, but it comes with a free 1-hour counselling session and it is based on whole genome sequencing. While an hour may not seem like a big thing, I more than once mentioned that genetic results can be tricky to interpret even for me – and I have a PhD in genetics. Thus products that come with counselling always get some bonus points from me. \u003C\u002Fp>\n\n\n\n\u003Cp>Their Diet-Lifestyle-Exercise packages include 125 reports, of which 15 are diet-related. The things they offer are very similar to the ones I listed above (alcohol\u002Fcaffeine\u002Ffat\u002Fsalt\u002Fcarbohydrate sensitivity, various intolerances, predispositions, optimal diet type). Another 20 offers nutritional info, mainly on vitamins and minerals. The rest of the reports come from other areas, such as fitness potential, and ancestral roots & genetic traits.\u003C\u002Fp>\n\n\n\n\u003Cp>If you are located in one of the less-fortunate countries of the world – like I am, services of major DNA testing companies are just not available in Hungary, my home country – worldwide shipping can be a big plus.  \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">It’s still challenging to decide what value you get\u003C\u002Fh3>\n\n\n\n\u003Cp>A relatively new advancement in the field is that more and more companies started working with already existing genetic test results. It is a viable business model given how tens of millions of people have already taken a test in the past few years. Offering new insights based on the existing data is a good take. \u003C\u002Fp>\n\n\n\n\u003Cp>If you’re looking for a general takeaway regarding nutrigenomics, here is what I see now. \u003C\u002Fp>\n\n\n\n\u003Cp>First, it is still challenging to determine what exactly you get for your money. While there are dozens of companies on the market selling these services, regulatory frameworks are not clear. Even the FDA, which is typically the first to set up such a framework for digital health inventions, lags behind. Thus users are pretty much left in the dark regarding the actual value of these offerings. At the moment there is no clear way to decide if you are spending money on meaningful health insights or well-crafted marketing messages.\u003C\u002Fp>\n\n\n\n\u003Cp>Secondly, although there are \u003Ca href=\"https:\u002F\u002Fscholar.google.hu\u002Fscholar?as_ylo=2022&q=nutrigenomics&hl=en&as_sdt=0,5\" target=\"_blank\" rel=\"noreferrer noopener\">growing numbers of scientific studies\u003C\u002Fa> on nutrigenomics, these don’t reflect the user’s point of view. \u003C\u002Fp>\n\n\n\n\u003Cp>And last, I can’t, at this moment, declare a clear takeaway on what you can and can’t learn from taking such a test. I will continue to keep an eye on the field and hope to see advancements on the regulatory side. \u003C\u002Fp>\n",{"rendered":1757,"protected":16},"\u003Cp>Despite the expectations and advancement of DNA analysis, nutrigenomics still struggles to gain momentum and become a mainstream service used by the masses.\u003C\u002Fp>\n",48473,{"_acf_changed":16,"footnotes":64},[440,5],[1016,82,1762,1763,1764],578,7693,7723,[452,453],[],[299,1407,103,109,1768,1033,588,1769],1973,4745,[1771,53,116,117,118,119,120,460,123,1045,135,1772,1773,1774,470,471],"post-48467","tag-nutrigenomics","tag-dna-test","tag-nutrigenomics_landscape",{"id":1758,"alt_text":1776,"caption":64,"description":1776,"media_type":149,"media_details":1777,"post":1743,"source_url":1803},"nutrigenomics",{"width":332,"height":333,"file":1778,"filesize":1779,"sizes":1780,"image_meta":1802},"2022\u002F12\u002Ftmf_article_345-01.png",66882,{"medium":1781,"large":1785,"thumbnail":1789,"medium_large":1793,"1536x1536":1794,"2048x2048":1798},{"file":1782,"width":179,"height":180,"mime-type":338,"filesize":1783,"source_url":1784},"tmf_article_345-01-370x208.png","29704","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-370x208.png",{"file":1786,"width":182,"height":183,"mime-type":338,"filesize":1787,"source_url":1788},"tmf_article_345-01-768x432.png","71664","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-768x432.png",{"file":1790,"width":177,"height":177,"mime-type":338,"filesize":1791,"source_url":1792},"tmf_article_345-01-150x150.png","14009","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-150x150.png",{"file":1786,"width":182,"height":183,"mime-type":338,"filesize":1787,"source_url":1788},{"file":1795,"width":349,"height":350,"mime-type":338,"filesize":1796,"source_url":1797},"tmf_article_345-01-1536x864.png","161650","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-1536x864.png",{"file":1799,"width":354,"height":355,"mime-type":338,"filesize":1800,"source_url":1801},"tmf_article_345-01-2048x1152.png","226457","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01-2048x1152.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F12\u002Ftmf_article_345-01.png",{"cta_type":364,"cta_color":64,"related_books":1805,"related_posts_footer":1806,"related_posts":16,"subtitle":64},[509,508,939],[1807,1808,1809],46621,21392,24840,{"yoast_wpseo_title":1811,"yoast_wpseo_metadesc":1812,"yoast_wpseo_canonical":1751},"The Global Nutrigenomics Landscape - The Medical Futurist","Dozens of companies sell nutrigenomics services, but there's no clear way to decide if you are spending money on health insights or marketing messages.",{"self":1814,"collection":1819,"about":1821,"author":1823,"replies":1825,"version-history":1828,"predecessor-version":1832,"wp:featuredmedia":1836,"wp:attachment":1839,"wp:term":1842,"curies":1853},[1815],{"href":1816,"targetHints":1817},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F48467",{"allow":1818},[27],[1820],{"href":220},[1822],{"href":223},[1824],{"embeddable":41,"href":226},[1826],{"embeddable":41,"href":1827},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=48467",[1829],{"count":1830,"href":1831},11,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F48467\u002Frevisions",[1833],{"id":1834,"href":1835},48557,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F48467\u002Frevisions\u002F48557",[1837],{"embeddable":41,"href":1838},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F48473",[1840],{"href":1841},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=48467",[1843,1845,1847,1849,1851],{"taxonomy":11,"embeddable":41,"href":1844},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=48467",{"taxonomy":248,"embeddable":41,"href":1846},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=48467",{"taxonomy":251,"embeddable":41,"href":1848},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=48467",{"taxonomy":254,"embeddable":41,"href":1850},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=48467",{"taxonomy":257,"embeddable":41,"href":1852},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=48467",[1854],{"name":39,"href":40,"templated":41},{"id":1856,"date":1857,"date_gmt":1858,"guid":1859,"modified":1861,"modified_gmt":1862,"slug":1863,"status":52,"type":53,"link":1864,"title":1865,"content":1867,"excerpt":1869,"author":61,"featured_media":1871,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1872,"categories":1873,"tags":1874,"project_category":1880,"contact_email_category":1881,"yst_prominent_words":1882,"class_list":1885,"better_featured_image":1892,"acf":1909,"yoast_meta":1919,"_links":1922},48099,"2022-11-24T10:00:00","2022-11-24T09:00:00",{"rendered":1860},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=48099&_wpnonce=91e96b224b&status=auto-draft&type=post","2024-01-11T18:04:26","2024-01-11T17:04:26","gene-pathway-analysis-in-action-3x4-dna-test-review","https:\u002F\u002Fmedicalfuturist.com\u002Fgene-pathway-analysis-in-action-3x4-dna-test-review",{"rendered":1866},"Gene Pathway Analysis In Action – 3×4 DNA Test Review",{"rendered":1868,"protected":16},"\n\u003Cp>In the past couple of years, I have taken at least 10 genetic tests, including this latest DNA test from\u003Ca href=\"https:\u002F\u002Fwww.3x4genetics.com\u002F\"> 3×4 Genetics\u003C\u002Fa>. This may seem excessive, but I have my reasons. I graduated from medical school as a genetic specialist and completed my PhD as a clinical genomics researcher, and although I turned to medical futurism, my original field never ceases to fascinate me. I’m very curious about how these tests advance and hope I might be able to provide insights for patients worldwide about what they can expect to learn from such tests and what those tests can really deliver.\u003C\u002Fp>\n\n\n\n\u003Cp>Thus, I didn’t hesitate for a second to get yet another test and try the pathway analysis 3×4 Genetics offers. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-resized is-style-default\">\u003Cimg decoding=\"async\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002FTMF-disclaimer-1-768x106.jpg\" alt=\"\" class=\"wp-image-48109\" width=\"800\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002FTMF-disclaimer-1-768x106.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002FTMF-disclaimer-1.jpg 991w\" sizes=\"(max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What is a pathway analysis?\u003C\u002Fh3>\n\n\n\n\u003Cp>“Traditional’ DNA tests typically offer you percentage values of disease risks, saying things like “you have 34% diabetes risk”. Even if that is an accurate estimate, it’s challenging to figure out what to do with that number, especially if the test provider’s control population may significantly differ from yours. In my case, living in the middle of Europe, such values would tell more if they were compared to the Caucasian population in Central Europe – which they are not. Therefore while you receive quantified results, it’s really hard to use those results in your health or disease management\u003C\u002Fp>\n\n\n\n\u003Cp>Pathway analysis tries a different approach, focusing not on single genes, but on the “functions” of those genes. \u003Ca href=\"https:\u002F\u002Fwww.frontiersin.org\u002Farticles\u002F10.3389\u002Ffphys.2015.00383\u002Ffull\">Pathway Analysis\u003C\u002Fa> (PA) aims to detect relevant groups of related genes and seeks to overcome the problem of interpreting overwhelmingly large lists of important but isolated genes detached from context. \u003C\u002Fp>\n\n\n\n\u003Cp>In plain English, PA aims to analyse the ways our bodies work and find the ones in which we may have problems. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">How to do the DNA test\u003C\u002Fh3>\n\n\n\n\u003Cp>The 3×4 test didn’t differ significantly from other tests. You collect your sample with a cheek swab and send the package back to the company. It then will be analysed in a lab, and you get the results in about a month.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"756\" height=\"408\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002FBerci-3x4DNA-3.jpg\" alt=\"DNA test results 3x4 Genetics\" class=\"wp-image-48103\"\u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>During this time you are asked to fill out a questionnaire that provides some background info. It includes your basic metrics, like age and weight, lifestyle questions about how you eat and how much you exercise, and some basic questions about your general health and mood, among others. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">The report on 36 pathways\u003C\u002Fh3>\n\n\n\n\u003Cp>3×4 Genetics was the first provider offering to send the final report in an encrypted mail, which I think is a big plus. The report evaluated my results in 36 pathways. These come from 6 \u003Cstrong>main categories\u003C\u002Fstrong> (and several sub-categories):\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>\u003Cstrong>Cellular \u003C\u002Fstrong>(Methylation, Inflammation, Oxidative stress, Detoxification)\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Systems \u003C\u002Fstrong>(Mood & behavior, Collagen & joints, Bone health, Glucose & insulin, Memory & brain health, Histamine overload, Hormone balance)\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Cardiovascular health\u003C\u002Fstrong> (Vascular health, Cholesterol, Blood clotting, Blood pressure)\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Energy\u003C\u002Fstrong> (Adipogenesis, Weight gain & weight loss resistance, Exercise response, Pro-inflammatory fat, Energy expenditure, Appetite\u002FSatiety\u002FIntake)\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Activity\u003C\u002Fstrong> (Power, Injury, Recovery, Training response, Endurance)\u003C\u002Fli>\n\n\n\n\u003Cli>\u003Cstrong>Nutritients\u003C\u002Fstrong> (Caffeine, Choline, Folate, Vitamin B12, Vitamin D, Fatty acids, Gluten, Vitamin C, Salt, Iron overload)\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cp>The workings of my 36 pathways were evaluated on a 4-grade scale (low-medium-high-very high), showing how close\u002Ffar I am from the optimal, with low being the closest to the ideal. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">The counselling was excellent\u003C\u002Fh3>\n\n\n\n\u003Cp>The follow-up counselling session is a crucial part of all genetic tests, I would never suggest anyone take a DNA test without professional support to analyse the results. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"751\" height=\"467\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002FBerci-3x4DNA-2.jpg\" alt=\"\" class=\"wp-image-48105\"\u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>This was by far the most useful counselling session I’ve ever had, offering methods, dietary and supplements advice to counter my problematic tendencies. I learned, for example, how not paying attention to proper resting can turn into anxiety, or how foods high in histamine might affect my psychological well-being. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">I did learn some new things, and they make sense\u003C\u002Fh3>\n\n\n\n\u003Cp>The report contained lots of things I was already aware of from my previous genetic tests, but it also offered some interesting new inputs. \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>It highlighted that I’m “highly resistant in releasing fat from stores”, which is in line with my extended family being unanimously obese. Without very carefully managing my weight, I would be overweight too. Fortunately, my lifestyle has kept my BMI under 23 for my entire life and I plan to keep on doing so.\u003C\u002Fli>\n\n\n\n\u003Cli>The report also explained why I was always good in sprint runs and terrible in long-distance runs: I am on the lower end of the endurance scale. On the other hand, I do particularly well in power sports. I also learned that I recover from exercises somewhat slowly, and need to support the process in several different ways.\u003C\u002Fli>\n\n\n\n\u003Cli>“As a slow metabolizer,” I also need to limit my caffeine intake – another insight that reinforces what I learned by experience. Drinking coffee after 3 pm will make me sleep unwell. Now I can be sure I’m not just imagining it. \u003C\u002Fli>\n\n\n\n\u003Cli>I also scored “very high” on the mood&balance scale, meaning I may be highly susceptible to an imbalance (anxiety, depression and related behaviours). As someone with a dopamine reuptake disorder, this also makes a lot of sense and explains my novelty-seeking nature, and why I constantly need to get into something new, like chess and baseball and so on. The counsellor also explained how important it is for me to find balance, to make sure my adventure-seeking would not cause anxiety.\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Pros and cons\u003C\u002Fh3>\n\n\n\n\u003Cp>All in all, I was happy with the process and the results, the company provided great customer support, although I think it would be impossible to properly interpret the report without the counselling session.\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Pros\u003C\u002Fstrong>:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>focus on genetic pathways\u003C\u002Fli>\n\n\n\n\u003Cli>excellent counselling session\u003C\u002Fli>\n\n\n\n\u003Cli>strong privacy measures\u003C\u002Fli>\n\u003C\u002Ful>\n\n\n\n\u003Cp>\u003Cstrong>Cons\u003C\u002Fstrong>:\u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\n\u003Cli>it was challenging to interpret the results without genetic counselling\u003C\u002Fli>\n\n\n\n\u003Cli>no online dashboard for the report, just a static PDF\u003C\u002Fli>\n\u003C\u002Ful>\n",{"rendered":1870,"protected":16},"\u003Cp>I tried the pathway analysis DNA test by 3×4 Genetics. This method offers a lot if you are looking for results you can actually use in health\u002Fdisease management. \u003C\u002Fp>\n",48159,{"_acf_changed":16,"footnotes":64},[5,442],[1763,1875,1876,1877,1016,1878,867,1879],7695,7697,7699,258,623,[452,453],[],[590,109,1768,1023,1033,1883,1884,588,589],3281,3877,[1886,53,116,117,118,119,120,123,462,1773,1887,1888,1889,1045,1890,906,1891,470,471],"post-48099","tag-dna-test-review","tag-3x4-genetics","tag-pathway-analysis","tag-genetic-test","tag-review",{"id":1871,"alt_text":1893,"caption":64,"description":64,"media_type":149,"media_details":1894,"post":1856,"source_url":1908},"Genetic test DNA test, genes",{"width":151,"height":152,"file":1895,"sizes":1896,"image_meta":1907},"2022\u002F11\u002F3x4Genetics_2.png",{"medium":1897,"large":1900,"thumbnail":1903,"medium_large":1906},{"file":1898,"width":179,"height":180,"mime-type":338,"source_url":1899},"3x4Genetics_2-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002F3x4Genetics_2-370x208.png",{"file":1901,"width":182,"height":183,"mime-type":338,"source_url":1902},"3x4Genetics_2-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002F3x4Genetics_2-768x432.png",{"file":1904,"width":177,"height":177,"mime-type":338,"source_url":1905},"3x4Genetics_2-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002F3x4Genetics_2-150x150.png",{"file":1901,"width":182,"height":183,"mime-type":338,"source_url":1902},{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F11\u002F3x4Genetics_2.png",{"cta_type":364,"cta_color":64,"related_books":1910,"related_posts_footer":1911,"related_posts":16,"subtitle":64,"key_takeaways":1914},[770,769,937],[1912,1913,1203],34955,15120,[1915,1917],{"title":1916},"\u003Cp>The 3×4 Genetics DNA test offers a unique pathway analysis approach, focusing on gene functions rather than just disease risk percentages, providing more actionable insights for health and disease management\u003C\u002Fp>\n",{"title":1918},"\u003Cp>The follow-up counseling session is essential for interpreting the complex results effectively, underscoring the importance of professional guidance in understanding and applying genetic test insights to personal health and lifestyle choices\u003C\u002Fp>\n",{"yoast_wpseo_title":1920,"yoast_wpseo_metadesc":1921,"yoast_wpseo_canonical":1864},"Gene Pathway Analysis In Action - 3x4 DNA Test Review","I tried the pathway analysis DNA test by 3x4 Genetics. This method offers a lot if you are looking for results you can actually use in health management.",{"self":1923,"collection":1928,"about":1930,"author":1932,"replies":1934,"version-history":1937,"predecessor-version":1941,"wp:featuredmedia":1945,"wp:attachment":1948,"wp:term":1951,"curies":1962},[1924],{"href":1925,"targetHints":1926},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F48099",{"allow":1927},[27],[1929],{"href":220},[1931],{"href":223},[1933],{"embeddable":41,"href":226},[1935],{"embeddable":41,"href":1936},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=48099",[1938],{"count":1939,"href":1940},12,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F48099\u002Frevisions",[1942],{"id":1943,"href":1944},54425,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F48099\u002Frevisions\u002F54425",[1946],{"embeddable":41,"href":1947},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F48159",[1949],{"href":1950},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=48099",[1952,1954,1956,1958,1960],{"taxonomy":11,"embeddable":41,"href":1953},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=48099",{"taxonomy":248,"embeddable":41,"href":1955},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=48099",{"taxonomy":251,"embeddable":41,"href":1957},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=48099",{"taxonomy":254,"embeddable":41,"href":1959},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=48099",{"taxonomy":257,"embeddable":41,"href":1961},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=48099",[1963],{"name":39,"href":40,"templated":41},{"id":1313,"date":1965,"date_gmt":1966,"guid":1967,"modified":1969,"modified_gmt":1970,"slug":1971,"status":52,"type":53,"link":1972,"title":1973,"content":1975,"excerpt":1977,"author":61,"featured_media":1979,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":1980,"categories":1981,"tags":1982,"project_category":1985,"contact_email_category":1986,"yst_prominent_words":1987,"class_list":1989,"better_featured_image":1993,"acf":2013,"yoast_meta":2018,"_links":2020},"2022-10-18T10:00:00","2022-10-18T08:00:00",{"rendered":1968},"http:\u002F\u002Fmedicalfuturist.com\u002F?p=15142","2022-10-18T09:36:04","2022-10-18T07:36:04","cheap-genome-sequencing-now","https:\u002F\u002Fmedicalfuturist.com\u002Fcheap-genome-sequencing-now",{"rendered":1974},"What Could You Do With Cheap Genome Sequencing Now?",{"rendered":1976,"protected":16},"\n\u003Cp>Genome sequencing does definitely not equal fortune telling: it cannot predict how long you will live or what your body mass index will look like. However, it can tell you a lot about your sensitivity to drugs, your family history or whether you are a carrier of monogenic conditions.\u003C\u002Fp>\n\n\n\n\u003Cp>After the Human Genome Project was completed 20 years ago (for a whopping $2.7 billion), the dream was to be able to sequence a person’s genome for 1000 USD. After this became feasible, the next dream was to make it even cheaper: now it costs around 200 USD after\u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Fthe-era-of-fast-cheap-genome-sequencing-is-here\u002F\" target=\"_blank\" rel=\"noreferrer noopener\"> Illumina’s innovation came to life\u003C\u002Fa>. \u003C\u002Fp>\n\n\n\n\u003Cp>What is the next dream? To be able to analyse the data and draw clinical conclusions from that.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Wait, I can already have my genome sequenced for $100, can’t I? \u003C\u002Fh3>\n\n\n\n\u003Cp>Although it is often not trivial from the names of various service offerings, there is a difference between full genome sequencing and the sub-$100 offers that are based on “Genome-wide association studies” or GWAS in short. \u003C\u002Fp>\n\n\n\n\u003Cp>You can imagine the difference like this: your DNA is a thick book. \u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Full genome sequencing\u003C\u002Fstrong> is reading the book from cover to cover. Still, we are not necessarily understanding all of the content, but we are able to read all the letters and sentences. \u003C\u002Fp>\n\n\n\n\u003Cp>Meanwhile, \u003Cstrong>GWAS\u003C\u002Fstrong> services – like 23andMe, Ancestry and the like – look into the book here and there, reading some sentences at one point, looking for a letter at another point and then using studies to find statistically relevant correlations between your results and results documented scientifically. Let’s say, ideally they provide you with an executive summary of the full story. \u003C\u002Fp>\n\n\n\n\u003Cp>The real significance of the huge price drop in full-genome sequencing – from the short-term, consumer point of view – is that it drives down the prices of all other services. You can’t sell a GWAS result for 200 dollars if anyone can get their full genomes sequenced for the same price.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What are your genes worth?\u003C\u002Fh3>\n\n\n\n\u003Cp>Certainly, with the advancement of technology, the price dropped faster and more dramatically than the fame and fortune of the blood-testing start-up, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fthe-12-most-overhyped-technologies-in-healthcare\u002F\" target=\"_blank\">Theranos\u003C\u002Fa>. In 30 years, the price fell from billions of dollars to the millesimal of the original cost.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-768x432.jpg\" alt=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Fthe-era-of-fast-cheap-genome-sequencing-is-here\u002F\" class=\"wp-image-47569\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-768x432.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-370x208.jpg 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-1536x864.jpg 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-2048x1153.jpg 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002F2021_Sequencing_cost_per_Human_Genome-scaled.jpg 1919w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>That all sounds fantastic and very exciting for every science-savvy person out there, but what should the average person do with it? What could you find out with the help of cheap genome sequencing?\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What could you learn from your DNA if I gave you the data right now?\u003C\u002Fh3>\n\n\n\n\u003Cp>I have had several genetic tests in my life. Among a handful of others, I had \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fi-got-my-whole-genome-sequenced-heres-what-i-learned\u002F\" target=\"_blank\">my whole genome sequenced\u003C\u002Fa> by Dante Labs, had the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fatlas-biomed-genetic-test-review\u002F\" target=\"_blank\">genetic test from Atlas Biomed\u003C\u002Fa>, and \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fmydna-review\u002F\" target=\"_blank\">another test by MyDNA\u003C\u002Fa>. I learned valuable takeaways from all of these, helping me form a lifestyle that aims to counter my risks. Knowing that I have a higher-than-average risk of melanoma makes me especially conscious about regular dermatology checkups and minimizing the UV load on my skin. I try to fight my elevated chance of developing type 2 diabetes by eating healthy, exercising regularly, not smoking and minimising stress. The fact that I am at risk of knee arthritis is another factor in maintaining a healthy weight.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"768\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002FDNA-loads-the-gun-768x768.png\" alt=\"\" class=\"wp-image-47587\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002FDNA-loads-the-gun-768x768.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002FDNA-loads-the-gun-150x150.png 150w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2017\u002F03\u002FDNA-loads-the-gun.png 1080w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Let’s see some practical, useful info you can learn from your own test:\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">a) Sensitivity to drugs\u003C\u002Fh4>\n\n\n\n\u003Cp>The \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.mydna.life\u002F\" target=\"_blank\">myDNA genetic test\u003C\u002Fa> promises to help you and your doctor personalise your treatment by selecting the most appropriate medications based on how your body metabolizes drugs and the doses that may work best for you. As a consequence, your physician could improve your health outcomes, reduce the risk of side effects and you could also save a significant amount of money by avoiding ineffective medications. It is the best embodiment of \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC2014592\u002F\" target=\"_blank\">pharmacogenetics\u003C\u002Fa> to date. Based on the cheek swab sample I provided them, the company was able to show whether I have drug sensitivity for various basic drug ingredients, as well as whether I will have side effects when taking given types of medications. Truly useful information!\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">b) Genealogy\u003C\u002Fh4>\n\n\n\n\u003Cp>One of the most common uses of DNA testing is in uncovering family genealogy. Using consumer DNA testing services, you can uncover your family lines going back several generations. You can identify your racial makeup, familial ties and geographical background. For example, I found out that I am distantly related to Benjamin Franklin, which is kind of cool. At least, I can refer to my leadership skills as something I inherited from one of my famous ancestors (well, at least I’m going to claim that…). If you have a genetic test with \u003Ca href=\"http:\u002F\u002Fwww.23andme.com\" target=\"_blank\" rel=\"noreferrer noopener\">23andme\u003C\u002Fa>, \u003Ca href=\"https:\u002F\u002Fwww.ancestry.com\u002Fdna\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">AncestryDNA\u003C\u002Fa> or \u003Ca href=\"https:\u002F\u002Fwww.familytreedna.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">FTDNA\u003C\u002Fa>, they will definitely provide you with information about your unique family history and past relations.\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">c) Information about monogenic medical conditions\u003C\u002Fh4>\n\n\n\n\u003Cp>In primary school, I had a very nice biology teacher, who tried to explain genetics through the genes which determine your hair colour. If you have parents with blond hair, you are most likely to become a blonde. However, if your dad is the carrier of brown hair genes, you might end up being brown-haired. So we have more genetic possibilities stored in ourselves than what actually appears. Concerning your health, it is really useful to know whether you have “monogenic medical conditions”. For example, a genetic test can show you whether you have any such conditions, which you might transmit to your children; and if your partner also has it, even cause health problems for them.\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">d) Information about your multifactorial medical conditions\u003C\u002Fh4>\n\n\n\n\u003Cp>Generally, there are two types of diseases. One of them is called the multifactorial disease, where genetic components and environmental factors play significant roles. When you get your genome sequenced, you will get to know certain risk factors, which show you how much chance you have of getting a particular disease later in your life. Thus, you can get to know yourself better and get personalised solutions for preventing such diseases to get you. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What you could definitely not learn from your genetic test\u003C\u002Fh3>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">1) No prophecies on your fate\u003C\u002Fh4>\n\n\n\n\u003Cp>Many believe that the sequenced genome carries information about the person’s fate itself: what kind of diseases they may have, or when they are going to die. But that is simply not true. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-full is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fgene-editing.jpg\" alt=\"tmf\" class=\"wp-image-43425\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fgene-editing.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F04\u002Fgene-editing-370x208.jpg 370w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Genetic tests usually provide information about how likely it is for a given person to be taken ill by a given disease, percentages and ranges for various risks that are “written” into our genetic code. Sometimes it impacts your life, sometimes it does not. It depends pretty much on your lifestyle. If you are susceptible to diabetes, but you have a healthy lifestyle, perhaps you will never be aware of that fact. However, if there are no signs of the risk of diabetes in your genetic code, but you are overweight, don’t regularly do sports and have a stressful life, you might also end up diabetic.\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">2) No definitive answers on your due date\u003C\u002Fh4>\n\n\n\n\u003Cp>Many believe that the genetic code is something static and never-changing as if written in the stone of Ayers Rock in Australia or the Rock of Gibraltar. Unfortunately, I have to disappoint everyone who thought that the genome is a constant imprint of our fate. It is rather an ever-changing roadmap where various DNA “regions” impact each other in complex and sometimes incomprehensible ways, altering it continuously.\u003C\u002Fp>\n\n\n\n\u003Cp>However, for me, the most absurd idea concerning genome sequencing was that you might find out the date of your death if you do a genetic test. It is an outright falsehood: we are not programmed through our DNA and you cannot know what and when will things happen to you. I also believe it is better that way. Let the universe work in its own ways while you work in your own.\u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">3) Healthcare is not prepared for mass genome sequencing\u003C\u002Fh4>\n\n\n\n\u003Cp>Many assume that with the drop in prices and the time necessary for mapping a whole genome, the potential in genetics and genetically-related medicine is widely known in medical circles, moreover, it is leveraged by more and more medical professionals. However, I have to disappoint again. Healthcare is definitely not prepared for mass genome sequencing. Although it is not niche anymore, most general practitioners are still not prepared to make sense of your DNA report and include its findings in their everyday practices. \u003C\u002Fp>\n\n\n\n\u003Ch4 class=\"wp-block-heading\">4. No recipe for super-humans\u003C\u002Fh4>\n\n\n\n\u003Cp>A couple of years ago, \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.vice.com\u002Fen_us\u002Farticle\u002Fchinas-taking-over-the-world-with-a-massive-genetic-engineering-program\" target=\"_blank\">China apparently started a massive genetic engineering program\u003C\u002Fa>: they sequenced the genome of 2000 individuals chosen as the smartest people on the planet to find out the genes which determine human intelligence. They believe(d) if they find it, they will be able to allow parents to choose the most intelligent zygote as their future kid. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-768x432.png\" alt=\"artificial womb\" class=\"wp-image-24181\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050-2048x1152.png 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2019\u002F06\u002F093_will_we_born_in_2050.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>I believe it is sheer nonsense. As I mentioned before, your DNA cannot determine your exact future and it definitely cannot tell your particular characteristics down to the ground. You cannot figure out your weight, intelligence, mood or any other future trait from genome sequencing since the environment, lifestyle or eating habits have just too much of an impact. It’s the same with your risks for multifactorial medical conditions. There is no definitive percentage, there are too many factors influencing such health issues.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Genetics loads the gun, lifestyle pulls the trigger\u003C\u002Fh3>\n\n\n\n\u003Cp>So while we have no impact on what we inherit from our ancestors (although the \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fcrispr\u002F\" target=\"_blank\">CRISPR genome editing method\u003C\u002Fa> might bring some changes there in the future), lifestyle depends on our decisions. We can improve it with data, feedback and good technologies. Also, the more we can learn from our genome, the more precautions we can take to prevent diseases or catch them as soon as possible. \u003C\u002Fp>\n\n\n\n\u003Cp>So, do not hesitate to order a genetic test (but be careful when choosing one and do not buy an uncontrolled test), and try to make some adjustments to your lifestyle based on the results and their interpretation by a genetic counsellor or your own physician. And of course, if you have any doubts or questions, I’m more than happy to help as well! Reach out to me on \u003Ca href=\"https:\u002F\u002Fwww.facebook.com\u002Fmedicalfuturist\u002F\">Facebook\u003C\u002Fa> or \u003Ca href=\"https:\u002F\u002Ftwitter.com\u002FBerci\">Twitter\u003C\u002Fa>.\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",{"rendered":1978,"protected":16},"\u003Cp>Genome sequencing does definitely not equal with fortune telling: it cannot predict how long you will live or what your body mass index will look like. However, it can tell you a lot about your sensitivity to drugs, your family history or whether you are a carrier of monogenic conditions.\u003C\u002Fp>\n",47669,{"_acf_changed":16,"footnotes":64},[5,442],[1983,75,1010,1016,1013,867,80,1984,82,704,84],355,261,[453],[],[1027,1029,1032,1033,105,1035,107,109,1988],1995,[1990,53,116,117,118,119,120,123,462,1991,128,1039,1045,1042,906,133,1992,135,733,137,471],"post-15142","tag-personalized-medicine","tag-genome",{"id":1979,"alt_text":1994,"caption":64,"description":64,"media_type":149,"media_details":1995,"post":1313,"source_url":2012},"TMF DNA sequence",{"width":1295,"height":1296,"file":1996,"sizes":1997,"image_meta":2011},"2022\u002F10\u002Ftmf_article_335-v2-01.png",{"medium":1998,"large":2001,"thumbnail":2004,"medium_large":2007,"1536x1536":2008},{"file":1999,"width":179,"height":180,"mime-type":338,"source_url":2000},"tmf_article_335-v2-01-370x208.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01-370x208.png",{"file":2002,"width":182,"height":183,"mime-type":338,"source_url":2003},"tmf_article_335-v2-01-768x432.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01-768x432.png",{"file":2005,"width":177,"height":177,"mime-type":338,"source_url":2006},"tmf_article_335-v2-01-150x150.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01-150x150.png",{"file":2002,"width":182,"height":183,"mime-type":338,"source_url":2003},{"file":2009,"width":349,"height":350,"mime-type":338,"source_url":2010},"tmf_article_335-v2-01-1536x864.png","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01-1536x864.png",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188},"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F10\u002Ftmf_article_335-v2-01.png",{"related_posts":16,"related_posts_footer":2014,"cta_type":364,"cta_color":64,"subtitle":64,"related_books":2017},[1913,2015,2016],17450,47495,[366,769,937],{"yoast_wpseo_title":1974,"yoast_wpseo_metadesc":2019,"yoast_wpseo_canonical":1972},"Genome sequencing can tell you a lot about your sensitivity to drugs, your family history or whether you're a carrier of monogenic conditions. Check it out!",{"self":2021,"collection":2026,"about":2028,"author":2030,"replies":2032,"version-history":2035,"predecessor-version":2039,"wp:featuredmedia":2043,"wp:attachment":2046,"wp:term":2049,"curies":2060},[2022],{"href":2023,"targetHints":2024},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15142",{"allow":2025},[27],[2027],{"href":220},[2029],{"href":223},[2031],{"embeddable":41,"href":226},[2033],{"embeddable":41,"href":2034},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=15142",[2036],{"count":2037,"href":2038},44,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15142\u002Frevisions",[2040],{"id":2041,"href":2042},47663,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F15142\u002Frevisions\u002F47663",[2044],{"embeddable":41,"href":2045},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F47669",[2047],{"href":2048},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=15142",[2050,2052,2054,2056,2058],{"taxonomy":11,"embeddable":41,"href":2051},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=15142",{"taxonomy":248,"embeddable":41,"href":2053},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=15142",{"taxonomy":251,"embeddable":41,"href":2055},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=15142",{"taxonomy":254,"embeddable":41,"href":2057},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=15142",{"taxonomy":257,"embeddable":41,"href":2059},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=15142",[2061],{"name":39,"href":40,"templated":41},{"id":1807,"date":2063,"date_gmt":2064,"guid":2065,"modified":2067,"modified_gmt":2068,"slug":2069,"status":52,"type":53,"link":2070,"title":2071,"content":2073,"excerpt":2075,"author":61,"featured_media":2077,"comment_status":63,"ping_status":63,"sticky":41,"template":64,"format":65,"meta":2078,"categories":2079,"tags":2082,"project_category":2088,"contact_email_category":2089,"yst_prominent_words":2090,"class_list":2096,"better_featured_image":2105,"acf":2125,"yoast_meta":2132,"_links":2134},"2022-06-07T10:00:00","2022-06-07T08:00:00",{"rendered":2066},"https:\u002F\u002Fmedicalfuturist.com\u002F?post_id=46621&_wpnonce=432be13e01&status=auto-draft&type=post","2022-06-09T18:07:04","2022-06-09T16:07:04","why-is-nutrigenomics-the-biggest-flop-in-digital-health","https:\u002F\u002Fmedicalfuturist.com\u002Fwhy-is-nutrigenomics-the-biggest-flop-in-digital-health",{"rendered":2072},"Why Is Nutrigenomics The Biggest Flop In Digital Health?",{"rendered":2074,"protected":16},"\n\u003Cp>If somebody had told me five years ago that I’d sooner review an A.I. guided portable ultrasound device than a nutrigenomics test, I would have laughed so hard. Yet, \u003Ca href=\"https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=_MvImEQhUzM\">here we are\u003C\u002Fa>, this ultrasound test is almost a year old now, and where is a nutrigenomics test I could finally lay my hands on? Not even close.\u003C\u002Fp>\n\n\n\n\u003Cp>This is THE digital health technology I have been waiting for the longest and still had no chance to try. At the moment I can’t name a single service, a single direct-to-consumer (DTC) solution focusing on this area while being available and being backed by scientific evidence. \u003C\u002Fp>\n\n\n\n\u003Cp>Why is that? I can name four reasons.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">But first, let’s explore, what is nutrigenomics at all? \u003C\u002Fh3>\n\n\n\n\u003Cp>In simple terms, a science that aims to understand how specific humans react differently to specific nutrients due to their individual genetic characteristics, and how we can utilise this knowledge for each individual. \u003C\u002Fp>\n\n\n\n\u003Cp>In even simpler terms: a promise of an advancement that can provide you with scientifically backed data on what, how and when you should eat and what to avoid – based on your DNA. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"432\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F08\u002F192_tmf-01-768x432.png\" alt=\"\" class=\"wp-image-29501\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F08\u002F192_tmf-01-768x432.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F08\u002F192_tmf-01-370x208.png 370w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F08\u002F192_tmf-01-1536x864.png 1536w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F08\u002F192_tmf-01-2048x1152.png 2048w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2020\u002F08\u002F192_tmf-01.png 1920w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Ffigure>\n\n\n\n\u003Cp>The more scientific \u003Ca href=\"https:\u002F\u002Fwww.nature.com\u002Fsubjects\u002Fnutrigenomics#:~:text=Nutrigenomics%20is%20the%20study%20of,variations%20affect%20the%20nutritional%20environment.\">definition by Nature\u003C\u002Fa> goes like this: “nutrigenomics is the study of the effects of food and food constituents on gene expression, and how genetic variations affect the nutritional environment. It focuses on understanding the interaction between nutrients and other dietary bioactives with the genome at the molecular level, to understand how specific nutrients or dietary regimes may affect human health.”\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Reason 1: It is extremely challenging to learn nutritionally guiding principles from genetic tests \u003C\u002Fh3>\n\n\n\n\u003Cp>The first reason why we are not even close to fulfilling my dream about a tech providing omnipotent guidance for how and what I should (and should not) eat is that genetic test results tell us a million things, but we need something very specific here. \u003C\u002Fp>\n\n\n\n\u003Cp>For a reliably working nutrigenomics test, scientists should be able to draw definitive conclusions from our DNA regarding the specific metabolism-related effects this or that protein causes. \u003C\u002Fp>\n\n\n\n\u003Cp>We are getting somewhere with bordering areas of science, like food intolerance and food allergy tests – but these are not based on our genetics. Similarly, nutritional guidance can be based on our microbiome (the important collective of our gut bacteria), but then again, this is not focusing on our genes in this generalised way.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Reason 2: Pricing will be very tricky\u003C\u002Fh3>\n\n\n\n\u003Cp>Even if we had the scientific toolset to provide the genetically backed data we need for a reliably working nutrigenomics test, chances are it would not come at a price people would be willing to pay. \u003C\u002Fp>\n\n\n\n\u003Cp>Just as 23andMe had to offer its solution underpriced to build a wide enough customer base (and acquire enough data they can sell to pharma companies to make up for that fat red minus at the bottom of their earnings report), a reliably working nutrigenomics test would likely be way too expensive for us everyday folks.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Reason 3: Nutrigenomics will not offer easy fixes for fast results\u003C\u002Fh3>\n\n\n\n\u003Cp>Whether we like it or not, we live in an era of quick fixes. A nutrigenomics test would definitely not provide simple, easy-to-follow solutions offering striking results in just 7 days. Without efforts.\u003C\u002Fp>\n\n\n\n\u003Cp>I wonder how many customers would be happy to dive into a definite knowledge pack that almost certainly demanded lifestyle and nutritional changes, and adaptation of a dietary regime that could only offer benefits in the long run. \u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image size-large is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"584\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F06\u002Ffood-healthy-lifestyle-eating-Photo-credit-Mohamed-Hassan-768x584.jpg\" alt=\"\" class=\"wp-image-46622\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F06\u002Ffood-healthy-lifestyle-eating-Photo-credit-Mohamed-Hassan-768x584.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2022\u002F06\u002Ffood-healthy-lifestyle-eating-Photo-credit-Mohamed-Hassan.jpg 1421w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003Cfigcaption>Photo: Mohamed Hassan, Creative Commons\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Of course, we all know (deep down) that this is the way, for having the health benefits of eating healthily we should actually eat healthily for years and decades. For the benefits of being sporty, we should exercise multiple times a week for years and decades. \u003C\u002Fp>\n\n\n\n\u003Cp>But having it written once and for all, based on our DNA? That might not be a thing masses of people will internalise quickly and happily. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Reason 4: All you see is bogus, fake science everywhere\u003C\u002Fh3>\n\n\n\n\u003Cp>The online world is just full of bogus solutions, services, and products that at first seem scientific, and it would make even the most experienced researcher sweat to try and find a single credible solution in this mass offering of snake oil wonders. How could an everyday person see through this jungle? It certainly is not an easy feat.\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">All in all\u003C\u002Fh3>\n\n\n\n\u003Cp>Of course, we are not giving up hope to be among the first ones to test a reliably working, accessible, DTC nutrigenomics test. While this time arrives, I will figuratively put nutrigenomics on my shelf of flops, right next to my – very solid – 3D printed cast. \u003C\u002Fp>\n",{"rendered":2076,"protected":16},"\u003Cp>Four reasons why we still don’t have reliably working nutrigenomics tests, which could tell us what we should eat based on our dna. \u003C\u002Fp>\n",21409,{"_acf_changed":16,"footnotes":64},[440,2080,280,2081,5,442],4879,510,[2083,2084,2085,2086,2087,1762],7581,7582,7583,7584,240,[453],[],[590,109,1033,2091,2092,2093,2094,2095],3057,3361,3699,3889,5411,[2097,53,116,117,118,119,120,460,2098,314,2099,123,462,2100,2101,2102,2103,2104,1772,471],"post-46621","category-lifestyle-medicine","category-future-of-food","tag-nutritients","tag-how-to-eat","tag-dna-food-test","tag-dna-diet","tag-food",{"id":2077,"alt_text":64,"caption":64,"description":64,"media_type":149,"media_details":2106,"post":1808,"source_url":2124},{"width":598,"height":442,"file":2107,"sizes":2108,"image_meta":2122},"2018\u002F08\u002FNutrigenomics-3.jpg",{"medium":2109,"large":2112,"thumbnail":2115,"medium_large":2118,"large_old_512x288":2119},{"file":2110,"width":157,"height":158,"mime-type":159,"source_url":2111},"Nutrigenomics-3-370x208.jpg","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F08\u002FNutrigenomics-3-370x208.jpg",{"file":2113,"width":163,"height":164,"mime-type":159,"source_url":2114},"Nutrigenomics-3-768x432.jpg","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F08\u002FNutrigenomics-3-768x432.jpg",{"file":2116,"width":168,"height":168,"mime-type":159,"source_url":2117},"Nutrigenomics-3-150x150.jpg","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F08\u002FNutrigenomics-3-150x150.jpg",{"file":2113,"width":163,"height":164,"mime-type":159,"source_url":2114},{"file":2120,"width":173,"height":174,"mime-type":159,"source_url":2121},"Nutrigenomics-3-512x288.jpg","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F08\u002FNutrigenomics-3-512x288.jpg",{"aperture":188,"credit":64,"camera":64,"caption":64,"created_timestamp":188,"copyright":64,"focal_length":188,"iso":188,"shutter_speed":188,"title":64,"orientation":188,"keywords":2123},[],"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F08\u002FNutrigenomics-3.jpg",{"cta_type":364,"cta_color":64,"subtitle":64,"related_books":2126,"related_posts_footer":2128,"related_posts":16},[508,2127,938],24763,[2129,2130,2131],16570,13135,21800,{"yoast_wpseo_title":2072,"yoast_wpseo_metadesc":2133,"yoast_wpseo_canonical":2070},"Four reasons why we still don't have reliably working nutrigenomics tests, which could tell us what we should eat based on our dna.",{"self":2135,"collection":2140,"about":2142,"author":2144,"replies":2146,"version-history":2149,"predecessor-version":2152,"wp:featuredmedia":2156,"wp:attachment":2159,"wp:term":2162,"curies":2173},[2136],{"href":2137,"targetHints":2138},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F46621",{"allow":2139},[27],[2141],{"href":220},[2143],{"href":223},[2145],{"embeddable":41,"href":226},[2147],{"embeddable":41,"href":2148},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=46621",[2150],{"count":1348,"href":2151},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F46621\u002Frevisions",[2153],{"id":2154,"href":2155},46634,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F46621\u002Frevisions\u002F46634",[2157],{"embeddable":41,"href":2158},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F21409",[2160],{"href":2161},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=46621",[2163,2165,2167,2169,2171],{"taxonomy":11,"embeddable":41,"href":2164},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=46621",{"taxonomy":248,"embeddable":41,"href":2166},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=46621",{"taxonomy":251,"embeddable":41,"href":2168},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=46621",{"taxonomy":254,"embeddable":41,"href":2170},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=46621",{"taxonomy":257,"embeddable":41,"href":2172},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=46621",[2174],{"name":39,"href":40,"templated":41},[],[],1785956501056]