[{"data":1,"prerenderedAt":485},["ShallowReactive",2],{"slug-3d-bioprinting-overview":3},{"post":4,"relatedPosts":245,"relatedBooks":395},{"id":5,"date":6,"date_gmt":7,"guid":8,"modified":10,"modified_gmt":11,"slug":12,"status":13,"type":14,"link":15,"title":16,"content":18,"excerpt":21,"author":23,"featured_media":24,"comment_status":25,"ping_status":25,"sticky":26,"template":27,"format":28,"meta":29,"categories":30,"tags":39,"project_category":71,"contact_email_category":78,"yst_prominent_words":79,"class_list":95,"better_featured_image":147,"acf":180,"yoast_meta":189,"_links":192},21115,"2022-05-19T10:00:00","2022-05-19T08:00:00",{"rendered":9},"http:\u002F\u002Fmedicalfuturist.com\u002F","2022-06-01T14:55:46","2022-06-01T12:55:46","3d-bioprinting-overview","publish","post","https:\u002F\u002Fmedicalfuturist.com\u002F3d-bioprinting-overview",{"rendered":17},"3D Bioprinting: Eradicating Transplantation Waiting Lists And Testing Drugs On Living Tissues",{"rendered":19,"protected":20},"\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">From time to time, news arises about 3D-printed organs.\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\"> On such occasions, people usually think that a machine can already create readily available, implantable human organs. However, the reality is far from this optimistic image.\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\"> \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Researchers worldwide are working on possible solutions: from a group that printed a \u003C\u002Fspan>\u003Ca href=\"http:\u002F\u002Fwww.xinhuanet.com\u002Fenglish\u002F2020-11\u002F24\u002Fc_139540203.htm\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">miniature kidney,\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> through technological solutions like BioAssemblyBot \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fposts\u002Fbioprinting-hand-36609058\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">we wrote about earlier, \u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">to entirely \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002F3dprintingindustry.com\u002Fnews\u002Fcarnegie-researchers-develop-fresh-new-method-of-3d-bioprinting-fully-sized-human-heart-models-179829\u002F\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">new methods\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> that can lead to patient-specific heart tissue printing. The list is long and set in a clinical setting.\u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\"> We checked out where the technology stands today and where it might lead us in healthcare tomorrow.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">\u003Cstrong>3D bioprinting can be the response to worldwide organ shortages and the increasing reluctance to test new cosmetic, chemical, and pharmaceutical products on animals.\u003C\u002Fstrong> Whether it will become a reality anytime soon is not certain, although research efforts have grown rapidly over the past years. As seen in \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=vqveljTzypM&feature=emb_imp_woyt\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">this video\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, the technology behind bioprinting is getting better and (much) faster. However, this hydrogen-based technology is still not bioprinting – it is not the content but the printing technology itself. However, a breakthrough might be just around the corner. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Here’s how bioprinting will break into healthcare revolutionising organ donations and animal testing.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003C!--more-->\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What is bioprinting?\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Put the term bioprinting next to Earth-invader androids, shiny spaceships in a post-apocalyptic setting, and you’ll get the next Hollywood blockbuster. However, as opposed to malevolent aliens, bioprinting not only exists in sci-fi movies, but it will also transform healthcare in the following decades. Before going into details, though, let’s dissect the technology itself.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\u003Cp>\u003Ciframe loading=\"lazy\" title=\"What Is 3D Bioprinting? - The Medical Futurist\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002F7Rnd2CGUQag?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>Three-dimensional (3D) bioprinting is a state-of-the-art technology that means creating living tissues, such as blood vessels, bones, heart or skin, via the \u003Ca rel=\"noopener\" href=\"https:\u002F\u002F3dprinting.com\u002Fwhat-is-3d-printing\u002F\" target=\"_blank\">additive manufacturing\u003C\u002Fa>\u003C\u002Fstrong>\u003Cspan style=\"font-weight: 400;\">\u003Cstrong> technology of 3D printing.\u003C\u002Fstrong> Traditional 3D printing implies the production of three-dimensional solid objects from a digital file, using a layering process. In its most common version, a source material, such as plastic, is liquefied, and then the machine adds layer after layer to the platform until you have a fully formed object.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Needless to say, printing organs is a “little bit” more complicated. In the early 2000s \u003C\u002Fspan>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fwww.economist.com\u002Fscience-and-technology\u002F2017\u002F01\u002F28\u002Fprinted-human-body-parts-could-soon-be-available-for-transplant\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">researchers discovered\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> that living cells could be sprayed through the nozzles of inkjet printers without damaging them. However, it is not enough to have the cells themselves, they need a nurturing environment to stay alive: food, water, and oxygen. Nowadays, these conditions are \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fhealth.howstuffworks.com\u002Fmedicine\u002Fmodern-technology\u002F3-d-bioprinting3.htm\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">provided by a microgel\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> – think of gelatin enriched with vitamins, proteins, and other life-sustaining compounds. Moreover, to create conditions fostering the fastest and most efficient cell growth, researchers plant the cells around 3D scaffolds made of biodegradable polymers or collagen so they can grow into fully functional tissue.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">How to 3D print an organ\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Let’s take the example of the bladder, a simpler organ consisting of only two types of cells. At first, researchers scan the patient’s organ to determine personalised size and shape. Then they create a scaffold to give cells something to grow on in three dimensions and add cells from the patient to this scaffold. That’s painstakingly\u003C\u002Fspan>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fhealth.howstuffworks.com\u002Fmedicine\u002Fmodern-technology\u002F3-d-bioprinting4.htm\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\"> labour-intensive work\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> and could take as long as eight weeks. Finally, a bioreactor creates the optimal environment for the cells to grow into an organ. When doctors finally place the organ in the patient, the scaffold has already disappeared or it disappears soon after surgery.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">This description cannot demonstrate how difficult and time-consuming the entire process is.\u003C\u002Fspan> \u003Cspan style=\"font-weight: 400;\">We are a long way, even decades away, from bioprinting fully functioning, complex organs; however, 3D bioprinting is already used to generate model tissues for research and is also used in \u003C\u002Fspan>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fwww.researchgate.net\u002Fpublication\u002F315500645_3D_bioprinting_technology_for_regenerative_medicine_applications\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">regenerative medicine\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">What can we print now?\u003C\u002Fh3>\n\n\n\n\u003Cp>Bioprinting has developed with incredible speed in recent years. Currently, it is possible to print \u003C\u002Fp>\n\n\n\n\u003Cul class=\"wp-block-list\">\u003Cli>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.nature.com\u002Farticles\u002Fs41413-022-00192-2\" target=\"_blank\">bones\u003C\u002Fa>\u003C\u002Fli>\u003Cli>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.frontiersin.org\u002Farticles\u002F10.3389\u002Ffbioe.2021.746564\u002Ffull\" target=\"_blank\">cartilage\u003C\u002Fa>\u003C\u002Fli>\u003Cli>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002F3dprintingindustry.com\u002Fnews\u002Fresearchers-successful-in-healing-deep-wounds-using-3d-bioprinted-skin-201912\u002F\" target=\"_blank\">skin\u003C\u002Fa>\u003C\u002Fli>\u003Cli>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002F3dprintingindustry.com\u002Fnews\u002Ftr-biofab-pulls-off-breakthrough-3d-bioprinted-liver-tissue-transplant-192682\u002F\" target=\"_blank\">liver tissue\u003C\u002Fa> – in theory\u003C\u002Fli>\u003C\u002Ful>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">From shapeshifters to microfuilds, these are the latest breakthroughs\u003C\u002Fh3>\n\n\n\n\u003Cp>Following the news of the bioprinting industry, we have come across 4 exciting new ideas\u002Fprojects that hold great promise for the future. These are:\u003C\u002Fp>\n\n\n\n\u003Cp>1. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.medgadget.com\u002F2022\u002F04\u002F3d-bioprinted-constructs-change-shape-over-time.html\" target=\"_blank\">3D Bioprinted Constructs Changing Shape Over Time\u003C\u002Fa>\u003C\u002Fp>\n\n\n\n\u003Cp>Researchers at the University of Illinois Chicago have developed a method to create 3D printed cell-loaded bioink constructs that can change shape over time, just like tissues in the body do. Incorporating crosslinking molecules into the printed hydrogels, some of which are UV light-sensitive, allows the constructs to undergo shape changes after printing. The technique could help scientists model the development of tissues that also undergo shape changes in response to external stimuli, such as bone or cartilage, or during healing and development. \u003C\u002Fp>\n\n\n\n\u003Cp>2. \u003Ca href=\"https:\u002F\u002F3dprintingindustry.com\u002Fnews\u002Fresearchers-turn-to-microfluidics-in-hopes-of-3d-printing-human-organs-208554\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">Microfluidics-based 3D bioprinting\u003C\u002Fa>\u003C\u002Fp>\n\n\n\n\u003Cp>A bioprinter based on microfluidics would operate by precisely manipulating liquids through tiny channels and could print structures measuring just tens of microns across. This is more akin to the single cellular scale and is reportedly what’s needed if we’re ever to make 3D printed organs a reality.\u003C\u002Fp>\n\n\n\n\u003Cp>3. \u003Ca href=\"https:\u002F\u002F3dprintingindustry.com\u002Fnews\u002Fboston-universitys-new-3d-printed-mini-human-heart-beats-on-its-own-208314\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">The 3D printed mini heart that beats on its own\u003C\u002Fa>\u003C\u002Fp>\n\n\n\n\u003Cp>The device was created using a combination of stem cell-derived human heart cells and micro-scale 3D printed acrylic parts, and it doesn’t rely on external power source, it beats on its own. Researchers hope it can be used to track how the heart grows in an embryo, how heart tissue is affected by diseases, and how effective new medications are in treating said diseases, all without the need for human testing.\u003C\u002Fp>\n\n\n\n\u003Cp>4. \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002F3dprintingindustry.com\u002Fnews\u002Fcollplant-to-trial-3d-bioprinted-breast-implants-in-breakthrough-animal-study-207127\u002F\" target=\"_blank\">3D bioprinted breast implant\u003C\u002Fa>\u003C\u002Fp>\n\n\n\n\u003Cp>CollPlant announced that the 3D bioprinted breast tissues it’s developing will enter in-vivo testing from Q2 2022. These grafts are designed to gradually degrade and be replaced by native tissues, in a safer alternative to breast augmentation procedures. \u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">A solution for organ shortages\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">The solution to alarming worldwide organ shortages comes from technology. 3D bioprinting is the response of technology to critical tissue shortages hampering medical professionals’ tasks and endangering many lives. In the U.S., a new person is added to the waiting list of organ donors \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.organdonor.gov\u002Fstatistics-stories\u002Fstatistics.html\" target=\"_blank\" rel=\"noreferrer noopener\">every 9 minutes\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">. The number of patients \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.organdonor.gov\u002Fstatistics-stories\u002Fstatistics\u002Fdata.html\" target=\"_blank\" rel=\"noreferrer noopener\">waiting for an organ donor\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> has multiplied five-fold in the last 26 years. \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.organdonor.gov\u002Fstatistics-stories\u002Fstatistics.html\" target=\"_blank\" rel=\"noreferrer noopener\">17 people die\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> every day due to the lack of available organs in the U.S. alone.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Other countries are not better off either. In 2018, over 150 000 patients \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.europarl.europa.eu\u002FRegData\u002Fetudes\u002FBRIE\u002F2020\u002F649363\u002FEPRS_BRI(2020)649363_EN.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">in Europe\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> were registered on organ waiting lists. In the U.K., \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.independent.co.uk\u002Flife-style\u002Fhealth-and-families\u002Forgan-donor-law-england-opt-out-register-children-max-keira-a9524216.html\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">408 patients\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> died while waiting for an organ in 2019. In 2020, the U.K.’s organ donation policy changed to an \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.theguardian.com\u002Fsociety\u002F2020\u002Fmay\u002F19\u002Fdeceased-uk-adults-to-be-deemed-organ-donors-in-opt-out-system#:~:text=All%20adults%20in%20England%20will,or%20the%20individual%20opts%20out.&text=Opt%2Dout%20has%20been%20a,has%20been%20law%20since%202015.\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">opt-in system\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, meaning every adult agrees to become an organ donor when they die unless they state that they do not wish to donate. This has remarkably decreased the waiting lines in the country.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cdiv class=\"wp-block-image wp-image-33357 size-full is-style-default\">\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"1000\" height=\"625\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Forgan-transplant-myths-1.jpg\" alt=\"\" class=\"wp-image-33357\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Forgan-transplant-myths-1.jpg 1000w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Forgan-transplant-myths-1-768x480.jpg 768w\" sizes=\"auto, (max-width: 1000px) 100vw, 1000px\" \u002F>\u003Cfigcaption>An illustration of several organs to answer common myths about organ donation.\u003C\u002Ffigcaption>\u003C\u002Ffigure>\u003C\u002Fdiv>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Closing the gaps\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">A team of researchers at Carnegie Mellon University have created a 3D bioprinting technique called  “Freeform Reversible Embedding of Suspended Hydrogels” (FRESH). During a panel discussion on the virtual \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fadditivemanufacturingstrategies.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">AMS Summit\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> in March 2021, the project’s team leader, Professor Adam Feinberg, noted that “\u003C\u002Fspan>\u003Ci>\u003Cspan style=\"font-weight: 400;\">we could have a bioprinted heart in an animal in 12 years\u003C\u002Fspan>\u003C\u002Fi>\u003Cspan style=\"font-weight: 400;\">.” Talking further about the \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002F3dprint.com\u002F278969\u002Fams-2021-deconstructing-the-timeline-to-bioprinted-organs\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">possible future\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> timeline for the technology, another expert, Katie Weimer, VP of Regenerative Medicine at \u003Ca href=\"https:\u002F\u002Fwww.3dsystems.com\u002Fbioprinting\" target=\"_blank\" rel=\"noreferrer noopener\">3D Systems\u003C\u002Fa>, said the issue is merely “\u003C\u002Fspan>\u003Ci>\u003Cspan style=\"font-weight: 400;\">an engineering problem\u003C\u002Fspan>\u003C\u002Fi>\u003Cspan style=\"font-weight: 400;\">.” \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003Cspan style=\"font-weight: 400;\">In a recent interview for our Patreon site, Erik Gatenholm, CEO of \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.cellink.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">CELLINK\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, estimated the same. He said, “\u003C\u002Fspan>\u003Ci>\u003Cspan style=\"font-weight: 400;\">we will see fully functioning organs within the next decade or so.” \u003C\u002Fspan>\u003C\u002Fi>\u003Cspan style=\"font-weight: 400;\">Gatenholm added, “\u003C\u002Fspan>\u003Ci>\u003Cspan style=\"font-weight: 400;\">scientists have been able to bioprint hearts, lungs, kidneys, skin, corneas and more throughout the last 5 years and are currently working towards developing full functioning organs. As of now, the industry is progressing at a steady pace due to the democratisation of 3D bioprinting technology.” \u003C\u002Fspan>\u003C\u002Fi>\u003C\u002Fp>\n\n\n\n\u003Cdiv class=\"wp-block-image wp-image-33359 size-full is-style-default\">\u003Cfigure class=\"aligncenter\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"900\" height=\"435\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002F3d-bioprinting-tissue-organs.jpg\" alt=\"\" class=\"wp-image-33359\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002F3d-bioprinting-tissue-organs.jpg 900w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002F3d-bioprinting-tissue-organs-768x371.jpg 768w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \u002F>\u003Cfigcaption>Source: from \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.sigmaaldrich.com\u002FUS\u002Fen\u002Ftechnical-documents\u002Ftechnical-article\u002Fcell-culture-and-cell-culture-analysis\u002F3d-cell-culture\u002F3d-bioprinting-bioinks\" target=\"_blank\">https:\u002F\u002Fwww.sigmaaldrich.com\u002FUS\u002Fen\u002Ftechnical-documents\u002Ftechnical-article\u002Fcell-culture-and-cell-culture-analysis\u002F3d-cell-culture\u002F3d-bioprinting-bioinks\u003C\u002Fa>\u003C\u002Ffigcaption>\u003C\u002Ffigure>\u003C\u002Fdiv>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">Bioprinting making waves on the market\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">At the AMS Summit, industry leaders went into an in-depth discussion on the commercialisation of 3D bioprinting. \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002F3dprint.com\u002F278969\u002Fams-2021-deconstructing-the-timeline-to-bioprinted-organs\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Several companies\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> that focus on bioprinting tissues or implants rather than organs themselves already have go-to-market products – like \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fparticle3d.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Particle3D\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.aspectbiosystems.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Aspect Biosystems\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Frokithealthcare.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Rokit Healthcare\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.viscientbiosciences.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Viscient Biosciences\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.dimensioninx.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Dimension Inx\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, and \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fpoietis.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Poietis\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">. But of course, major players on the field like Swedish \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.cellink.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">CELLINK\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> or US-based \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Forganovo.com\u002F\" target=\"_blank\" rel=\"noreferrer noopener\">\u003Cspan style=\"font-weight: 400;\">Organovo\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> also have their technologies on the market already. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cdiv class=\"wp-block-image is-style-default\">\u003Cfigure class=\"aligncenter\">\u003Ca class=\"img\" href=\"https:\u002F\u002Fwww.3dprintingmedia.network\u002Fwp-content\u002Fuploads\u002F2021\u002F02\u002F3dpbm-Map-of-Bioprinting-Technologies-and-Companies-February-2021-8.svg\" rel=\"noopener\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"549\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002FScreen-Shot-2021-03-10-at-12.26.58-768x549.png\" alt=\"\" class=\"wp-image-33361\"\u002F\u003C\u002Fa srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002FScreen-Shot-2021-03-10-at-12.26.58-768x549.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002FScreen-Shot-2021-03-10-at-12.26.58.png 1229w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \u002F>\u003C\u002Fa>\u003Cfigcaption>See enlarged image \u003Ca href=\"https:\u002F\u002Fwww.3dprintingmedia.network\u002Fwp-content\u002Fuploads\u002F2021\u002F02\u002F3dpbm-Map-of-Bioprinting-Technologies-and-Companies-February-2021-8.svg\" target=\"_blank\" rel=\"noopener\">here\u003C\u002Fa>\u003C\u002Ffigcaption>\u003C\u002Ffigure>\u003C\u002Fdiv>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">The pioneers of 3D bioprinting\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">\u003Cstrong>The most well-known tissue engineering company is the San Diego-based company, \u003Ca href=\"https:\u002F\u002Forganovo.com\u002F\" target=\"_blank\" rel=\"noopener\">Organovo\u003C\u002Fa>.\u003C\u002Fstrong> It has been actively developing a line of human tissues for use in medical research and drug discovery. They create highly customised 3D human tissues as dynamic models of healthy and diseased human biology for drug development and recently have been in the news for creating miniature \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.sciencedaily.com\u002Freleases\u002F2020\u002F11\u002F201124190532.htm\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">human kidneys\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> in the lab, together with the Murdoch Children’s Research Institute.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Today the company still lacks the much-talked-about FDA approval for its technology. It focuses on replacing animals in testing processes, novel drug discovery and custom disease models, as well as single-cell RNA sequencing. Organovo seeks to have multiple IND filings with the FDA by the end of 2025.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>And as printing tissues is a revolutionary approach, Organovo has also hit the wall with some of its projects. The company announced to kill its ‘liver patch’ project in 2019,  an initiative that seemed very promising for years, and which must have burned a good amount of funding along the way. \u003C\u002Fp>\n\n\n\n\u003Cp class=\"has-text-align-left\">\u003Cstrong>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fwww.cellink.com\u002F\" target=\"_blank\">CELLINK\u003C\u002Fa>\u003C\u002Fstrong>\u003Cspan style=\"font-weight: 400;\">\u003Cstrong> has been doing great over the past years.\u003C\u002Fstrong> The company develops both bioprinters and bioprinting materials for providing ready-to-print or use models for researchers and healthcare providers to enable 3D cell culture, personalised medicine, and enhanced therapeutics. Their approach helped to decrease the price of bioprinting devices enormously, which allowed more and more research or education institutions and organisations to buy one of these machines – and this inevitably led to even more research and more breakthrough in the industry. Through \u003C\u002Fspan>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fnews.cision.com\u002Fcellink-ab\u002Fr\u002Fcellink-has-entered-into-an-agreement-to-acquire-the-advanced-robotics-and-diagnostics-automation-co,c3286729\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">acquisitions\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> and \u003C\u002Fspan>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fwww.news-medical.net\u002Fnews\u002F20200515\u002FCELLINK-announces-partnership-with-AstraZeneca-to-provide-advanced-3D-bioprinted-liver-organoids.aspx\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">cooperations\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, CELLINK indeed became a bioconvergence \u003C\u002Fspan>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fwww.3dprintingmedia.network\u002Fcytena-readies-to-launch-new-system-for-single-cell-bioprinting\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">powerhouse\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>The two pioneers – Organovo and Cellink – have recently \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002F3dprintingcenter.net\u002Fthe-first-patent-war-in-the-world-of-3d-bioprinting-organovo-vs-cellink-aka-bico\u002F\" target=\"_blank\">clashed in a legal battle\u003C\u002Fa>, both accusing the other of the use of their own patented technologies. The companies eventually \u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fir.organovo.com\u002Fnews-releases\u002Fnews-release-details\u002Fupdate-organovo-and-bico-cellink-reach-licensing-agreement\" target=\"_blank\">came to an agreement \u003C\u002Fa>in March 2022. \u003C\u002Fp>\n\n\n\u003Cblockquote class=\"twitter-tweet\" data-width=\"550\" data-dnt=\"true\">\n\u003Cp lang=\"en\" dir=\"ltr\">Researchers figured out how to make clear human organs \u003Ca href=\"https:\u002F\u002Ft.co\u002F4T7IBGIyLu\">pic.twitter.com\u002F4T7IBGIyLu\u003C\u002Fa>\u003C\u002Fp>\n\u003Cp>— Seeker by The Verge (@Seeker) \u003Ca href=\"https:\u002F\u002Ftwitter.com\u002FSeeker\u002Fstatus\u002F1354498155635744773?ref_src=twsrc%5Etfw\">January 27, 2021\u003C\u002Fa>\u003C\u002Fp>\u003C\u002Fblockquote>\n\u003Cp>\u003Cscript async src=\"https:\u002F\u002Fplatform.twitter.com\u002Fwidgets.js\" charset=\"utf-8\">\u003C\u002Fscript>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Biotech veteran, US-based \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.unither.com\u002F\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">United Therapeutics\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> develops pharmaceuticals to treat vascular diseases and cancer. The company started \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.3dnatives.com\u002Fen\u002Fcollplant-united-therapeutics-kidney-bioprinting-051020204\u002F\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">bioprinting kidneys\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, together with Israeli CollPlant, to use the latter’s unique bioink technology and human collagen in \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.prnewswire.com\u002Fil\u002Fnews-releases\u002Fcollplant-and-united-therapeutics-announce-exercise-of-option-that-will-expand-their-collaboration-to-include-3d-bioprinting-of-human-kidneys-for-transplant-301134527.html\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">the process\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> that aims to reduce worldwide organ shortages.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">With 3D bioprinting against testing drugs on animals\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002F3d-bioprinting-overview\u002F\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">Bioprinting\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> can also help eliminate the need for testing new drugs on animals. Replacing lengthy and expensive clinical trials, which often have no results, is a good market opportunity whereby pharma companies could save billions of dollars. Testing medication on mice, rabbits or other animals is in many cases not efficient as the particular drug could still have a different effect on people.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">On the other hand, 3D printed tissue \u003Ca rel=\"noreferrer noopener\" class=\"img\" href=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Fmachine-learning-in-healthcare.png\" target=\"_blank\"\u003C\u002Fa>proves to be\u003C\u002Fa> an effective means of testing \u003C\u002Fspan>\u003Ca rel=\"noreferrer noopener\" href=\"https:\u002F\u002Fwww.med-technews.com\u002Fnews\u002Flatest-medtech-news\u002Facademia-and-business-to-develop-3d-printed-pancreas-for-tes\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">new pharmaceuticals\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, meaning that drugs can be thoroughly assessed and brought to market more quickly, all without harming animal test subjects. Moreover, as testing cosmetics on animals has always been even more controversial than testing for medical purposes, with the emergence of \u003C\u002Fspan>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002Fwww.youtube.com\u002Fwatch?v=ilzynZvZm3c\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">3D printing human skin\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">, testing cosmetics on animals could disappear once and for all.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone wp-image-21123 size-full is-style-default\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"580\" src=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F07\u002Ftesting-drugs-on-animals.png\" alt=\"Bioprinting\" class=\"wp-image-21123\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F07\u002Ftesting-drugs-on-animals.png 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F07\u002Ftesting-drugs-on-animals-768x512.png 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F07\u002Ftesting-drugs-on-animals-512x341.png 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption>Source: www.nabr.org\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">In situ bioprinting\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">The solution means 3D printing tissues directly at the point of injury – no matter whether it’s about bones, tissues or skin. In the next decade, doctors may, therefore, be able to scan wounds and spray on layers of cells to heal them very rapidly. The first results are already out: \u003C\u002Fspan>\u003Cspan style=\"font-weight: 400;\">Australian researchers from UNSW Sydney \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fnewsroom.unsw.edu.au\u002Fnews\u002Fhealth\u002Fscientists-use-novel-ink-3d-print-%E2%80%98bone%E2%80%99-living-cells-0\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">developed\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> a ceramic-based ink that can print bone-like structures without the use of chemicals or radiation. This technology may help surgeons to 3D print bone parts with living cells – practically to print a replacement bone, including living cells, directly inside a patient’s body.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">Scientists in China are also working on “in vivo in situ” solutions and \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.genengnews.com\u002Fnews\u002Fbioprinting-in-vivo-offers-potential-therapy-for-gastric-wounds\u002F\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">developed\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> a tool that can carry out tissue repair inside the body, used on patients with gastric wounds.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\u003Cp>\u003Ciframe loading=\"lazy\" title=\"In-situ contour bioprinting of skin tissue on a mouse\" width=\"640\" height=\"360\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FGFIDKGY3y5I?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen>\u003C\u002Fiframe>\u003C\u002Fp>\n\n\n\n\u003Ch3 class=\"wp-block-heading\">The challenges of 3D bioprinting\u003C\u002Fh3>\n\n\n\n\u003Cp>\u003Cstrong>The Medical Futurist doesn’t like to ruin optimistic and positive visions for the future, but bioprinting faces severe challenges from technological, financial, and regulatory perspectives.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">\u003Cstrong>The most burning issue is the question of regulation.\u003C\u002Fstrong> Leaving the market unregulated might lead to a thriving black market. As soon as scaffolds are available and methods are open source, people worldwide might be tempted to start printing unregulated and untested biomaterials and sell them to desperate people. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">The FDA has a \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.fda.gov\u002Fmedical-devices\u002Fproducts-and-medical-procedures\u002F3d-printing-medical-devices\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">short segment\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> on 3D bioprinting, but it does not explicitly cover living cells. Those applications are due to \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.sme.org\u002Ftechnologies\u002Farticles\u002F2020\u002Fapril\u002Fscience-precedes-regulations-in-bioprinting\u002F\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">go through\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> the FDA’s Center for Biologics Evaluation and Research. As the FDA does not regulate bioprinting but the \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.fda.gov\u002Fmedical-devices\u002Fproducts-and-medical-procedures\u002F3d-printing-medical-devices\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">medical devices \u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\">and solutions \u003C\u002Fspan>\u003Ci>\u003Cspan style=\"font-weight: 400;\">coming out\u003C\u002Fspan>\u003C\u002Fi>\u003Cspan style=\"font-weight: 400;\"> of the printers, \u003C\u002Fspan>\u003Ca href=\"https:\u002F\u002Fwww.pewtrusts.org\u002Fen\u002Fresearch-and-analysis\u002Fissue-briefs\u002F2020\u002F10\u002Fwhat-is-medical-3d-printing-and-how-is-it-regulated\" target=\"_blank\" rel=\"noopener\">\u003Cspan style=\"font-weight: 400;\">regulations\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> still lag behind the technology’s speed. \u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cspan style=\"font-weight: 400;\">A 2020 October decision to give \u003C\u002Fspan>\u003Ca rel=\"noopener\" href=\"https:\u002F\u002F3dprint.com\u002F273977\u002Ffda-says-a-d-a-m-s-3d-printed-bones-are-eligible-for-510k-clearance\u002F\" target=\"_blank\">\u003Cspan style=\"font-weight: 400;\">510k clearance\u003C\u002Fspan>\u003C\u002Fa>\u003Cspan style=\"font-weight: 400;\"> to A.D.A.M., a Ukrainian company to work on 3D printed bone implants out of bioceramics, however, indicated that the regulatory body is about to speed up in the field. A.D.A.M. is already in the testing phase and expected to be on the market in 2022 – after getting the FDA approval.\u003C\u002Fspan>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>3D Bioprinting is an overly complicated technology, and so are its many technological, and biological challenges; ethical and regulatory issues can already be seen from this brief introduction. It won’t be applied in practice overnight, but it’s going to be a reality to deal with within a decade.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs?hl=en&cc_lang_pref=en&cc=1\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",false,{"rendered":22,"protected":20},"\u003Cp>Full overview of how 3D bioprinting will break into healthcare revolutionizing organ donations & animal testing.\u003C\u002Fp>\n",6,33403,"closed",true,"","standard",{"_acf_changed":20,"footnotes":27},[31,32,33,34,35,36,37,38],498,504,500,798,521,490,499,800,[40,41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68,69,70],6803,236,6783,6805,246,6785,6807,271,6787,963,6809,289,551,6789,964,6811,355,667,6791,1199,375,6793,383,6795,425,6797,6799,130,6801,152,6781,[72,73,74,75,76,77],947,948,949,950,952,953,[],[80,81,82,83,84,85,86,87,88,89,90,91,92,93,94],3201,3341,3391,3397,3415,3451,1719,3457,1883,3459,2133,3461,2903,4491,2947,[96,14,97,98,99,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,123,124,125,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,145,146],"post-21115","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-3d-printing","category-artificial-intelligence","category-biotechnology","category-digital-health-research","category-future-medicine","category-future-of-pharma","category-healthcare-design","category-healthcare-policy","tag-rokit-healthcare","tag-fda-2","tag-bioassemblybot","tag-viscient-biosciences","tag-future","tag-additive-manufacturing","tag-poietis","tag-health","tag-microgel","tag-organ","tag-united-therepautics","tag-innovation","tag-organs","tag-carnegie","tag-organ-donation","tag-animal-testing","tag-personalized-medicine","tag-tissue-engineering","tag-ams","tag-organovo","tag-rna","tag-regenerative-medicine","tag-science-fiction","tag-fresh","tag-technology-2","tag-cellink","tag-particle3d","tag-3d-printing-2","tag-aspect-biosystems","tag-bioprinting","tag-kidney","project_category-company","project_category-developers","project_category-educators","project_category-medical-professionals","project_category-policy-makers","project_category-researchers",{"id":24,"alt_text":148,"caption":27,"description":149,"media_type":150,"media_details":151,"post":5,"source_url":179},"3D printing","3D bioprinting","image",{"width":152,"height":153,"file":154,"sizes":155,"image_meta":177},1920,1080,"2021\u002F03\u002Ftmf_article_249-01.png",{"medium":156,"large":162,"thumbnail":167,"medium_large":171,"1536x1536":172},{"file":157,"width":158,"height":159,"mime-type":160,"source_url":161},"tmf_article_249-01-370x208.png","370","208","image\u002Fpng","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01-370x208.png",{"file":163,"width":164,"height":165,"mime-type":160,"source_url":166},"tmf_article_249-01-768x432.png","768","432","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01-768x432.png",{"file":168,"width":169,"height":169,"mime-type":160,"source_url":170},"tmf_article_249-01-150x150.png","150","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01-150x150.png",{"file":163,"width":164,"height":165,"mime-type":160,"source_url":166},{"file":173,"width":174,"height":175,"mime-type":160,"source_url":176},"tmf_article_249-01-1536x864.png","1536","864","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01-1536x864.png",{"aperture":178,"credit":27,"camera":27,"caption":27,"created_timestamp":178,"copyright":27,"focal_length":178,"iso":178,"shutter_speed":178,"title":27,"orientation":178},"0","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2021\u002F03\u002Ftmf_article_249-01.png",{"related_posts":20,"related_posts_footer":181,"cta_type":185,"cta_color":27,"subtitle":27,"related_books":186},[182,183,184],17898,43409,22374,"subscribe",[187,188],31417,24761,{"yoast_wpseo_title":190,"yoast_wpseo_metadesc":191,"yoast_wpseo_canonical":15},"3D Bioprinting - Overview of How Bioprinting Will Break Into Healthcare","3D Bioprinting: Full overview of how 3D bioprinting will break into healthcare revolutionizing organ donations & animal testing.",{"self":193,"collection":199,"about":202,"author":205,"replies":208,"version-history":211,"predecessor-version":215,"wp:featuredmedia":219,"wp:attachment":222,"wp:term":225,"curies":241},[194],{"href":195,"targetHints":196},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F21115",{"allow":197},[198],"GET",[200],{"href":201},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts",[203],{"href":204},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftypes\u002Fpost",[206],{"embeddable":26,"href":207},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fusers\u002F6",[209],{"embeddable":26,"href":210},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcomments?post=21115",[212],{"count":213,"href":214},48,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F21115\u002Frevisions",[216],{"id":217,"href":218},46607,"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fposts\u002F21115\u002Frevisions\u002F46607",[220],{"embeddable":26,"href":221},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia\u002F33403",[223],{"href":224},"https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fmedia?parent=21115",[226,229,232,235,238],{"taxonomy":227,"embeddable":26,"href":228},"category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcategories?post=21115",{"taxonomy":230,"embeddable":26,"href":231},"post_tag","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Ftags?post=21115",{"taxonomy":233,"embeddable":26,"href":234},"project_category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fproject_category?post=21115",{"taxonomy":236,"embeddable":26,"href":237},"contact_email_category","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fcontact_email_category?post=21115",{"taxonomy":239,"embeddable":26,"href":240},"yst_prominent_words","https:\u002F\u002Fapi.medicalfuturist.com\u002Fwp-json\u002Fwp\u002Fv2\u002Fyst_prominent_words?post=21115",[242],{"name":243,"href":244,"templated":26},"wp","https:\u002F\u002Fapi.w.org\u002F{rel}",[246],{"id":184,"date":247,"date_gmt":248,"guid":249,"modified":251,"modified_gmt":252,"slug":253,"status":13,"type":14,"link":254,"title":255,"content":257,"excerpt":259,"author":23,"featured_media":261,"comment_status":25,"ping_status":25,"sticky":26,"template":27,"format":28,"meta":262,"categories":263,"tags":266,"project_category":279,"contact_email_category":280,"yst_prominent_words":281,"class_list":286,"better_featured_image":302,"acf":341,"yoast_meta":350,"_links":353},"2018-11-22T14:00:44","2018-11-22T12:00:44",{"rendered":250},"https:\u002F\u002Fmedicalfuturist.com\u002F","2022-05-27T10:06:39","2022-05-27T08:06:39","can-money-buy-you-longevity-and-health","https:\u002F\u002Fmedicalfuturist.com\u002Fcan-money-buy-you-longevity-and-health",{"rendered":256},"Can Money Buy You Longevity And Health?",{"rendered":258,"protected":20},"\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"5px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp style=\"color: #555;font-size: 12px;line-height: 14px\">THIS ARTICLE HAS NOT BEEN UPDATED SINCE 2018. THE INFORMATION SHARED IN THE ARTICLE WAS ACCURATE AT THE TIME OF ITS PUBLICATION, BUT IT MAY BE OUT OF DATE NOW. \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fmagazine\">BROWSE OUR LATEST ARTICLES HERE\u003C\u002Fa>\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\u003C\u002Ftbody>\u003C\u002Ftable>\n\n\n\n\u003Cp>Better treatment options, dietary conditions and (perhaps) less stress could make the life of the rich also healthier. However, when it comes to longevity and aging, do they really have better chances? Can the upper 0.1 percent secure their health for long decades or even reverse the process of growing old? Could society somehow also benefit from the quest of the richest for longevity?\u003C\u002Fp>\n\n\n\n\u003C!--more-->\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Are health and longevity on the shopping list?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>You can have an awful lot of things with money. For a starter, you can buy ice cream or Nutella, which are synonymous to self-love, so the Beatles was only partly right in singing that you can’t buy love. If you’re stuffed with cash, you might \u003Ca href=\"https:\u002F\u002Fmoneyinc.com\u002F20-expensive-things-world\u002F\">afford your very own parking space in downtown Manhattan\u003C\u002Fa>, it will cost you $1 million, but who counts that if you want to secure a place for your newest Gold Plated Bugatti Veyron? That little toy would cost you $10 million, but that’s still peanuts compared to the History Supreme Yacht that went on the market for $4.5 billion. That’s the \u003Ca href=\"https:\u002F\u002Ftradingeconomics.com\u002Fcountry-list\u002Fgdp\">entire GDP of Barbados and Latvia\u003C\u002Fa>, although to be fair to the Baltic country, it was in its least well performing year.\u003C\u002Fp>\n\n\n\n\u003Cp>Nevertheless, my personal favorite is the \u003Ca href=\"https:\u002F\u002Fdornob.com\u002Ffor-real-1-6-million-dollar-magnetic-hover-bed-floats-on-air\u002F\">magnetic hover bed that floats in air\u003C\u002Fa>. Who says the future is not nigh? For a dirt cheap $1.6 million, you can sleep several inches above the ground. Whatever you dream about, someone will sell that for you. \u003Cstrong>There’s an abundance of unique cars, art pieces, islands or crystals to purchase if you are a billionaire. But whom do you pay if you want to live forever? Or just a few decades more, perhaps?\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22376\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"653\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDagobert-Duck.jpg\" alt=\"longevity\" class=\"wp-image-22376\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDagobert-Duck.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDagobert-Duck-768x576.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FDagobert-Duck-512x384.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption>Source: www.aminoapps.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Up to a point, money does matter\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>Both staying healthy and healing from a condition cost enormous sums of money (well, for the average person, not the Bugatti-buying 0.1 percent). Americans are even worse off than other developed nations as the US spent 17.8 percent of its GDP on health care in 2016. Meanwhile, the average spending of 11 high-income countries assessed in a report published in the \u003Ca href=\"https:\u002F\u002Fjamanetwork.com\u002Fjournals\u002Fjama\u002Ffullarticle\u002F2674671\">Journal of the American Medical Association\u003C\u002Fa> — Canada, Germany, Australia, the U.K, Japan, Sweden, France, the Netherlands, Switzerland, Denmark, and the U.S. — was only 11.5 percent.\u003C\u002Fp>\n\n\n\n\u003Cp>Moreover, the \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fis-crowdfunding-the-grim-future-of-health-insurance\">average cost of hospital stays for cancer patients in 2015 was $31,390\u003C\u002Fa>, according to government figures — about half that year’s median household income. Moreover, \u003Ca href=\"https:\u002F\u002Fwww.ncbi.nlm.nih.gov\u002Fpmc\u002Farticles\u002FPMC3273528\u002F\">medical expenses are the leading cause of bankruptcy in the United States, according to a study that\u003C\u002Fa> indicated about 62 percent of personal bankruptcies in 2007 were reportedly due to medical bills, even though most of those people had insurance — up from about 46 percent in 2001.\u003C\u002Fp>\n\n\n\n\u003Cp>It is even reported widely that the differences in the financial background of people cause visible biological differences. Dr. David Himmelstein, the co-founder of the Physicians for a National Health Program and a lecturer in medicine at Harvard Medical School, told Healthline that \u003Cstrong>the \u003Ca href=\"https:\u002F\u002Fwww.healthline.com\u002Fhealth-news\u002Fcan-money-determine-how-long-you-live#2\">gap between the wealthiest and poorest Americans is about 10 years for women and 15 for men\u003C\u002Fa>, so there is a big spread with more affluent people living much longer than the poorer masses. And some are even expecting the widening of the chasm\u003C\u002Fstrong>.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22375\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"653\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FLife-expectancy-gap.jpg\" alt=\"longevity\" class=\"wp-image-22375\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FLife-expectancy-gap.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FLife-expectancy-gap-768x576.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FLife-expectancy-gap-512x384.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption>Source: www.independent.co.uk\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>You may lose the battle against cancer regardless of your resources\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>Still, diseases, especially cancer, seem to take down even the most resourceful and entrepreneurial minds, unfortunately. Steve Jobs, just to mention one of the most brilliant. The iconic Apple CEO died seven years ago from pancreatic cancer. \u003Ca href=\"https:\u002F\u002Fwww.livescience.com\u002F16414-steve-jobs-pancreatic-cancer-deadly.html\">He was reportedly treated for a rare form of the disease\u003C\u002Fa>, pancreatic neuroendocrine tumor. \u003Ca href=\"http:\u002F\u002Fwww.myhealthnewsdaily.com\u002Fpancreatic-cancer-radiation-chemotherapy-treatment-0256\u002F\">Pancreatic cancers\u003C\u002Fa> come with a meager survival rate: 75 percent of patients die in less than a year after diagnosis, and 94 percent die within five years, according to PCAN.\u003C\u002Fp>\n\n\n\n\u003Cp>Paul Allen, Co-Founder of Microsoft, and billionaire investor \u003Ca href=\"https:\u002F\u002Fwww.washingtonpost.com\u002Flocal\u002Fobituaries\u002Fpaul-allen-microsoft-co-founder-and-billionaire-investor-dies-at-xx\u002F2018\u002F10\u002F15\u002F17884968-d0c6-11e8-8c22-fa2ef74bd6d6_story.html?noredirect=on&utm_term=.38764c0b3a81\">died in October 2018\u003C\u002Fa>. He battled non-Hodgkin’s lymphoma previously in 2009 successfully, but he announced approximately 15 days before his death that his lymphoma had returned. The aggressive disease had taken him down too quickly.\u003C\u002Fp>\n\n\n\n\u003Cp>It is not commonplace to emphasize that debilitating medical conditions and death are unfortunately universal: they can affect anyone, regardless of wealth or social standing. Billionaires and their families are not immune to cancer, dyslexia, diabetes – or aging and death for that matter. Although they put a lot of hope into science to change that.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22377\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"457\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FCancer-Chemotherapy.jpg\" alt=\"longevity\" class=\"wp-image-22377\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FCancer-Chemotherapy.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FCancer-Chemotherapy-768x403.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FCancer-Chemotherapy-512x269.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption>Source: www.usatoday.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Billionaires get in the fight \u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>More than anyone else, billionaires want to stay healthy and live as long as possible. Preferably forever. \u003Cstrong>They usually pursue two strategies here: some are willing to pay ungodly sums of money to undergo various therapies – even experiments – which promise to make them younger, while others are pouring their dollars countlessly into research on longevity, aging or curing diseases.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>However, as \u003Ca href=\"https:\u002F\u002Fwww.newyorker.com\u002Fmagazine\u002F2017\u002F04\u002F03\u002Fsilicon-valleys-quest-to-live-forever\">The New Yorker’s journalist on the quest to understand the buzz about research on longevity and aging in the Silicon Valley remarked\u003C\u002Fa>, if we cured cancer we would add only 3.3 years to an average life; solving heart disease could get us an extra four. If we eliminated all diseases, the average lifespan might extend into the nineties. Thus, several billionaires go instead for financing research on how to slow aging and make humans live way beyond 100 while keeping them healthy. Seems just as easy as falling off a log.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Stem cells and blood transfusions?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>The anti-aging arsenal is vast and filled everything from face creams through fasting to \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002Fare-you-going-to-wake-up-from-cryosleep\">cryotherapies\u003C\u002Fa>, enthusiasts have even been \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Fpeter-diamandis-is-the-latest-tech-futurist-betting-on-stem-cells\u002F\">organizing a “Longevity Soiree” in San Francisco\u003C\u002Fa> every year for a decade now. However, one of the creepiest methods seems to be young-blood transfusions.  The bizarre concept invokes vampires, the middle ages, and human sacrifice. For example, in the 1700s, Countess Erzsebet Bathory was the ruler of a massive estate in Upper Hungary, and according to the legend she killed dozens of young virgins to drink their blood to stay young and be loved by her husband. Historians say that the Habsburg dynasty was eager to get their hands on the estate, so they spread around some nasty gossips and put her on a show trial with several forced confessions against her. Nevertheless, the story shows that the idea of older individuals getting new energy from the young has been around for centuries.\u003C\u002Fp>\n\n\n\n\u003Cp>At the turn of the 20\u003Csup>th\u003C\u002Fsup> century, a Russian physician experimented with young-blood transfusions, but \u003Ca href=\"https:\u002F\u002Fwww.newyorker.com\u002Fmagazine\u002F2017\u002F04\u002F03\u002Fsilicon-valleys-quest-to-live-forever\">he died when injected himself with blood from a student who had both malaria and tuberculosis\u003C\u002Fa>. In 2005, a Stanford lab announced that heterochronic parabiosis, or an exchange of blood between older and younger mice, rejuvenated the livers and muscles of the older ones. Currently, \u003Cstrong>a Silicon Valley company, Ambrosia Medical, charges $8,000 to fill the veins of people with blood serum from donors aged 16 to 25 to get a fresh dose of rejuvenating energy.\u003C\u002Fstrong> The highly popular enterprise recently finished its \u003Ca href=\"https:\u002F\u002Fwww.businessinsider.com\u002Fyoung-blood-transfusions-aging-disease-ambrosia-2017-1\">first clinical trial\u003C\u002Fa> and plans to launch its first clinic in New York City at the end of this year.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22378\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"435\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FYoung-Blood.jpg\" alt=\"longevity\" class=\"wp-image-22378\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FYoung-Blood.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FYoung-Blood-768x384.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FYoung-Blood-512x256.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption>Source: www.newsweek.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Cp>Others wishing to defy aging place their bets on young plasma, stem cells or super pills. Peter Diamandis, the father of \u003Ca href=\"https:\u002F\u002Fwww.humanlongevity.com\u002F\">Human Longevity Inc\u003C\u002Fa>, a biotechnology company he co-founded with \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002F2004\u002F08\u002Fventer\u002F\">genomics guru Craig Venter\u003C\u002Fa>, went on to establish \u003Cstrong>\u003Ca href=\"https:\u002F\u002Fwww.celularity.com\u002F\">Celularity,\u003C\u002Fa> a $250 million company, together with stem cell pioneer Robert Hariri. They are devoted to \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Fpeter-diamandis-is-the-latest-tech-futurist-betting-on-stem-cells\u002F\">using stem cells to turn back the clock on aging\u003C\u002Fa>. \u003C\u002Fstrong>That’s not the only company promising longevity through stem cells. A number of affluent individuals pay for \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Funtested-stem-cell-clinics-get-free-ads-at-clinicaltrialsgov\u002F\">somewhat shady stem cell clinical trials\u003C\u002Fa>, which the FDA want to put an end to in the short run.\u003C\u002Fp>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Pills to take for a long life?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>Some put their faith in the power of simple, swallowable medicine. The father of singularity, Ray Kurzweil takes around 100 supplements a day to keep him fresh and energized. He says that \u003Ca href=\"https:\u002F\u002Fwww.newyorker.com\u002Fmagazine\u002F2017\u002F04\u002F03\u002Fsilicon-valleys-quest-to-live-forever\">around the 2030s, small nanobots will roam around in our bodies and the brain to clean up all the damage that aging has done\u003C\u002Fa>. By 2045, he plans to upload his entire consciousness into the cloud and unite with artificial intelligence.\u003C\u002Fp>\n\n\n\n\u003Cp>Others experiment with powerful drugs, such as metformin. It is a diabetes drug that may extend healthy lifespan. Stem cell pioneer, Hariri, swears by the medication. The most daring are rumored to use \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002F2015\u002F04\u002Fdrug-testing-on-dogs\u002F\">rapamycin\u003C\u002Fa>, a \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Fsilicon-valleys-immortalists-will-help-us-all-stay-healthy\u002F\">powerful drug that prevents organ transplant rejection\u003C\u002Fa>. Rapamycin inhibits a key metabolic pathway called mTOR that caloric restriction shuts down, initiating a process where dysfunctional cellular components are degraded and recycled.\u003C\u002Fp>\n\n\n\n\u003Cp>In spite of every nice-sounding and trendy looking attempts at slowing aging, Maria Konovalenko, a PhD student in the joint program on Biology of Aging between the Buck Institute and University of Southern California, investigating also the role of mTOR signaling in aging and the differentiation of epithelial stem cells in the airway as part of one of her projects, told The Medical Futurist that the two most potent existing solutions are still – diet and exercise. \u003Cem>Existing research, for instance, of Luigi Fontana at the University of Washington in St. Louis, suggests that reducing calorie intake can improve certain health parameters in people. Janet Lord from the University of Birmingham, UK, demonstrated the longevity benefits of exercise, \u003C\u002Fem>she explained. So far, no drug or young-blood transfusion therapy could undermine this thesis – but what if we only need time and money for that?\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22380\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"696\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FLive-Longer.jpg\" alt=\"longevity\" class=\"wp-image-22380\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FLive-Longer.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FLive-Longer-768x614.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FLive-Longer-512x410.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption>Source: www.time.com\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Longevity and immortality research lights up the Silicon Valley\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>\u003Cstrong>Billionaires who started to fund research projects into aging and death seem to at least accept the fact that they cannot solve this issue from one day to another. Nevertheless, they are confident in saying they will have a solution – only the above mentioned two components are necessary: time and money.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>The co-founder of Google, Larry Page, and Sergey Brin established \u003Ca href=\"https:\u002F\u002Fwww.calicolabs.com\u002F\">Calico\u003C\u002Fa> to figure out the secret to a long, healthy life by studying the genes of animals which live far longer than humans. However, the company is extremely secretive. \u003Ca href=\"https:\u002F\u002Fwww.newyorker.com\u002Fmagazine\u002F2017\u002F04\u002F03\u002Fsilicon-valleys-quest-to-live-forever\">The New Yorker said all that’s known is\u003C\u002Fa> that it’s tracking a thousand mice from birth to death to try to determine “biomarkers” of aging. These are biochemical substances whose levels predict morbidity; that it has a colony of naked mole rats, which live for thirty years and are amazingly ugly; and that it has invested in drugs that may prove helpful with diabetes and Alzheimer’s.\u003C\u002Fp>\n\n\n\n\u003Cp>Jeff Bezos and Peter Thiel are funding \u003Ca href=\"https:\u002F\u002Funitybiotechnology.com\u002F\">Unity Biotechnology\u003C\u002Fa>, a Brisbane-based company \u003Ca href=\"https:\u002F\u002Fwww.cnbc.com\u002F2018\u002F08\u002F29\u002F-jeff-bezos-is-backing-this-scientist-who-is-working-on-a-cure-for-aging.html\">focusing in particular on senescent cells\u003C\u002Fa> — older cells that have stopped dividing and appear to be one of the causes of the onset of the diseases associated with aging. Unity keeps on designing drugs and treatments that can make a person functional and free of the diseases related to aging for as long as possible – starting with osteoarthritis as the first condition to tackle. The anti-aging pioneer, \u003Ca href=\"https:\u002F\u002Fwww.ft.com\u002Fcontent\u002F238cc916-e935-11e6-967b-c88452263daf\">Aubrey deGrey\u003C\u002Fa>, also focuses on an “engineering” approach designed to keep the process of aging below the threshold at which it turns into life-threatening disease. In order to step up efforts, even more, Joon Yun, a healthcare hedge fund investor launched \u003Ca href=\"http:\u002F\u002Fpaloaltoprize.com\u002F\">The Palo Alto Prize\u003C\u002Fa>, a $1 million competition to solve aging. He believes it’s only a matter of time until someone “hacks the code of aging.”\u003C\u002Fp>\n\n\n\n\u003Cp>In spite of the publicity and interest among the investor community in aging-related biotech start-ups, though, Konovalenko believes that support has been quite modest so far. \u003Cem>The main problem is that the aging research field has only just become ready for translating its first low hanging fruit. There’s plenty more fruit, but it hangs quite a lot higher. In order to get to it, there has to be more funding for basic research. Obviously, people want rejuvenation therapies as soon as possible, but those may be several decades away, \u003C\u002Fem>she added.\u003C\u002Fp>\n\n\n\n\u003Cfigure class=\"wp-block-image alignnone size-full wp-image-22381\">\u003Cimg loading=\"lazy\" decoding=\"async\" width=\"870\" height=\"653\" src=\"https:\u002F\u002F1712507217.rsc.cdn77.org\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FTelomeres.jpg\" alt=\"longevity\" class=\"wp-image-22381\" srcset=\"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FTelomeres.jpg 870w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FTelomeres-768x576.jpg 768w, https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FTelomeres-512x384.jpg 512w\" sizes=\"auto, (max-width: 870px) 100vw, 870px\" \u002F>\u003Cfigcaption>Source: www.med.stanford.edu\u003C\u002Ffigcaption>\u003C\u002Ffigure>\n\n\n\n\u003Ch2 class=\"wp-block-heading\">\u003Cstrong>Can you make death a choice?\u003C\u002Fstrong>\u003C\u002Fh2>\n\n\n\n\u003Cp>Thus, despite research efforts and plenty of ideas what genes, cells or processes could take part in aging and which need to be manipulated to reverse the clock – the research community doesn’t seem to be close to a breakthrough yet. And to dampen Silicon Valley’s optimism, we have to recognize that we \u003Ca href=\"https:\u002F\u002Fwww.wired.com\u002Fstory\u002Fsilicon-valleys-immortalists-will-help-us-all-stay-healthy\u002F\">haven’t made much progress in extending the outer limit of the human lifespan so far.\u003C\u002Fa> Yes, more people are living longer because we’ve gotten better at nutrition, curing acute conditions such as infections, and treating a handful of chronic diseases. \u003Cstrong>But the maximum reported age at death has plateaued at around 115 years.\u003C\u002Fstrong>\u003C\u002Fp>\n\n\n\n\u003Cp>\u003Cstrong>At the moment, humanity is much better at ideas presented in sci-fi movies or series than in realistic achievements\u003C\u002Fstrong>. We are dreaming about \u003Ca href=\"https:\u002F\u002Fmedicalfuturist.com\u002F3d-bioprinting-overview\">3D-printed tissues or even organs\u003C\u002Fa> replacing failing inner bodily structures in the future; or about cloning humans for filthy rich individuals to keep them healthy (The Island) or uploading their consciousness into the cloud while finding happiness in a virtual reality (Black Mirror – San Junipero). Although Konovalenko believes that the first idea about bioprinted organs might help restore damaged or diseased organs in the distant future and as a result, healthspan might increase in people.\u003C\u002Fp>\n\n\n\n\u003Cp>However, for the moment it seems that the rich aren’t getting closer to eternal youth and immortality either – no matter how optimistic they are. Konovalenko thinks that they still have to wait at least for another 10 years. \u003Cem>The first therapies would be developed against very particular diseases, that’s already on the horizon. I think it’s safe to predict that the first ones can be approved within the next 10 years. It is a possibility that systemic interventions into mechanisms of aging can be developed within the next couple of decades, but they will also be approved against a particular age-related disease, \u003C\u002Fem>she explained.\u003C\u002Fp>\n\n\n\n\u003Cp>And what can you do to cheat fate a little bit and gain healthier years? If you are a billionaire, start investing heavily in basic research into the mechanisms of aging. In such a way, scientists could figure out the secrets of longevity earlier and the entire society would benefit from the new knowledge. This way, Konovalenko says that money can even buy longevity for real. Wouldn’t that be better than purchasing your next luxury car?\u003C\u002Fp>\n\n\n\n\u003Cp>Nevertheless, if you have a little less money to spend on science, as a starter, quit smoking if you haven’t done that already. That means 10 years of your life on average! Then, make sure you go to college. Jay Olshanky, professor of public health at the University of Illinois at Chicago \u003Ca href=\"http:\u002F\u002Ftime.com\u002Fmoney\u002F2973691\u002Fretirement-planning-longer-life-annuity\u002F\">suggested\u003C\u002Fa> that better-educated Americans – those with four or more years of college – tend to live two to five years longer than the national averages. Beyond that – we cannot say anything you haven’t known already: healthy diet, doing sports and plenty of sleep.\u003C\u002Fp>\n\n\n\n\u003Ctable style=\"width: 100%; border-collapse: collapse; background-color: #eee; border-top: 4px solid #444;\" cellpadding=\"10px\">\n\u003Ctbody>\n\u003Ctr>\n\u003Ctd style=\"width: 100%;\">\n\u003Cp>\u003Cstrong>At The Medical Futurist, we are building a community for making a bold vision about the future of healthcare reality today.\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Ciframe loading=\"lazy\" width=\"560\" height=\"315\" src=\"https:\u002F\u002Fwww.youtube.com\u002Fembed\u002FFIbMejImnxs\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture\" allowfullscreen=\"\">\u003C\u002Fiframe>\n\u003Cp>If you’d like to support this mission, we invite you to \u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">join The Medical Futurist Patreon Community\u003C\u002Fa>. A community of empowered patients, future-oriented healthcare professionals, concerned health policymakers, sensible health tech developers, and enthusiastic medical students. If there were ever a time to join us, it is now. Every contribution, however big or small, powers our research and sustains our future.\u003C\u002Fp>\n\u003Cp>\u003Ca href=\"https:\u002F\u002Fwww.patreon.com\u002Fthemedicalfuturist\">\u003Cstrong style=\"background-color: #e71d3299; color: #000;\">Click here to support The Medical Futurist from as little as $3\u003C\u002Fstrong>\u003C\u002Fa> – it only takes a minute. Thank you.\u003C\u002Fp>\n\u003C\u002Ftd>\n\u003C\u002Ftr>\n\u003C\u002Ftbody>\n\u003C\u002Ftable>\n\u003Cp> \u003C\u002Fp>\n",{"rendered":260,"protected":20},"\u003Cp>Better treatment options, dietary conditions and (perhaps) less stress could make the life of the rich also healthier. However, when it comes to longevity and aging, do they really have better chances? Can the upper 0.1 percent secure their health for long decades or even reverse the process of growing old? Could society somehow also benefit from the quest of the richest for longevity?\u003C\u002Fp>\n",22382,{"_acf_changed":20,"footnotes":27},[264,265,35],511,506,[267,268,269,270,271,272,273,274,51,275,276,277,278],1145,669,924,925,927,1140,260,1141,1142,373,1143,1144,[],[],[282,283,284,88,285],1571,1583,1723,3585,[287,14,97,98,99,100,101,288,289,106,290,291,292,293,294,295,296,297,121,298,299,300,301],"post-22374","category-bioethics","category-cyborgization","tag-stem-cell","tag-blood","tag-longevity","tag-immortality","tag-aging","tag-age","tag-genetics","tag-aging-research","tag-life-sciences","tag-research","tag-silicon-valley","tag-eternal-life",{"id":261,"alt_text":303,"caption":304,"description":27,"media_type":150,"media_details":305,"post":184,"source_url":340},"longevity","Source: www.inhabitat.com",{"width":306,"height":36,"file":307,"sizes":308,"image_meta":338},870,"2018\u002F11\u002FAnti-Aging-Pill.jpg",{"medium":309,"large":315,"thumbnail":320,"medium_large":324,"large_old_512x288":325,"thumbnail_old_150x150":330,"medium_old_370x208":331,"medium_large_old_768x432":332,"large_old_512x288_old_512x288":335},{"file":310,"width":311,"height":312,"mime-type":313,"source_url":314},"Anti-Aging-Pill-370x208.jpg",370,208,"image\u002Fjpeg","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FAnti-Aging-Pill-370x208.jpg",{"file":316,"width":317,"height":318,"mime-type":313,"source_url":319},"Anti-Aging-Pill-768x433.jpg",768,433,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FAnti-Aging-Pill-768x433.jpg",{"file":321,"width":322,"height":322,"mime-type":313,"source_url":323},"Anti-Aging-Pill-150x150.jpg",150,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FAnti-Aging-Pill-150x150.jpg",{"file":316,"width":317,"height":318,"mime-type":313,"source_url":319},{"file":326,"width":327,"height":328,"mime-type":313,"source_url":329},"Anti-Aging-Pill-512x288.jpg",512,288,"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FAnti-Aging-Pill-512x288.jpg",{"file":321,"width":169,"height":169,"mime-type":313,"source_url":323},{"file":310,"width":158,"height":159,"mime-type":313,"source_url":314},{"file":333,"width":164,"height":165,"mime-type":313,"source_url":334},"Anti-Aging-Pill-768x432.jpg","https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FAnti-Aging-Pill-768x432.jpg",{"file":326,"width":336,"height":337,"mime-type":313,"source_url":329},"512","288",{"aperture":178,"credit":27,"camera":27,"caption":27,"created_timestamp":178,"copyright":27,"focal_length":178,"iso":178,"shutter_speed":178,"title":27,"orientation":178,"keywords":339},[],"https:\u002F\u002Fcdn.medicalfuturist.com\u002Fwp-content\u002Fuploads\u002F2018\u002F11\u002FAnti-Aging-Pill.jpg",{"related_posts":342,"related_posts_footer":346,"cta_type":27,"cta_color":27,"subtitle":27,"related_books":20},[343,344,345],11980,13151,22071,[347,348,349],20749,21879,22332,{"yoast_wpseo_title":351,"yoast_wpseo_metadesc":352,"yoast_wpseo_canonical":254},"Can Money Buy You Longevity And Health? - The Medical Futurist","When it comes to longevity, do the rich have better chances? Can the upper 0.1% secure their health for long decades or even reverse the process of 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